Differential abundances of AQP3 and AQP5 in reproductive tissues from dogs with and without cryptorchidism (41 views)
Anim Reprod Sci (ISSN: 0378-4320linking), 2021 May; 228: 106735-106735.
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Paper type: Journal Article,
Impact factor: 2.145, 5-year impact factor: 0
Url: Not available.
Keywords: Aquaporin, Cryptorchidism, Epididymis, Testis,
Affiliations:
*** IBB - CNR ***
Department of Veterinary Medicine and Animal Production, University of Naples "Federico II", Via Delpino 1, 80137, Naples, Italy.
Department of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy
Institute of Biostructures and Bioimages, National Research Council, Via De Amicis 95, 80131, Naples, Italy.
Institute for Anatomy and Cell Biology, Department of Medical Cell Biology Justus Liebig University Giessen, Aulweg 123, 35385, Giessen, Germany.
References:
Not available.
Anim Reprod Sci (ISSN: 0378-4320linking), 2021 May; 228: 106735-106735.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.145, 5-year impact factor: 0
Url: Not available.
Keywords: Aquaporin, Cryptorchidism, Epididymis, Testis,
Affiliations:
*** IBB - CNR ***
Department of Veterinary Medicine and Animal Production, University of Naples "Federico II", Via Delpino 1, 80137, Naples, Italy.
Department of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy
Institute of Biostructures and Bioimages, National Research Council, Via De Amicis 95, 80131, Naples, Italy.
Institute for Anatomy and Cell Biology, Department of Medical Cell Biology Justus Liebig University Giessen, Aulweg 123, 35385, Giessen, Germany.
References:
Not available.
Differential abundances of AQP3 and AQP5 in reproductive tissues from dogs with and without cryptorchidism
Aquaporins (AQPs) are integral transmembrane proteins facilitating transport of water and small solutes, such as glycerol and urea, between cells. In male reproductive tracts, AQPs maintain a milieu conducive for sperm formation, maturation, and storage. The aim of this study was to clarify effects of testicular and epidydimal function on male fertility by investigating localisation and abundances of AQP3 and AQP5 in testes and epididymal segments from dogs with and without unilateral cryptorchidism. Immunohistochemistry results indicated AQP3 and AQP5 have different distribution patterns in reproductive tissues of dogs with and without unilateral cryptorchidism. The AQP3, an aquaglyceroprotein, is present in different germ and Sertoli cells in testis of dogs without cryptorchidism. The AQP5 protein was not detected in germ cells but was present in Sertoli and Leydig cells and in endothelia of blood vessels. In cryptorchid dogs, AQP3 was detected in early-developing germ and Sertoli cells, and AQP5 had a distribution pattern similar to testes of dogs without cryptorchidism. In the epididymis, AQP3 and AQP5 were localised in epithelial cells of dogs with and without cryptorchidism in a cell-specific manner. The AQP3 and AQP5 protein was in larger abundance in the gonads from dogs with and without cryptorchidism. In contrast, AQP3 and AQP5 abundance increased in each segment of the cryptorchid epididymis, likely as a compensatory mechanism associated with the pathologic condition. These results indicate involvement of AQP3 and AQP5 in spermatogenesis and sperm maturation. Results from the present study indicate dogs are a useful for comparative reproductive biology studies.
Aquaporins (AQPs) are integral transmembrane proteins facilitating transport of water and small solutes, such as glycerol and urea, between cells. In male reproductive tracts, AQPs maintain a milieu conducive for sperm formation, maturation, and storage. The aim of this study was to clarify effects of testicular and epidydimal function on male fertility by investigating localisation and abundances of AQP3 and AQP5 in testes and epididymal segments from dogs with and without unilateral cryptorchidism. Immunohistochemistry results indicated AQP3 and AQP5 have different distribution patterns in reproductive tissues of dogs with and without unilateral cryptorchidism. The AQP3, an aquaglyceroprotein, is present in different germ and Sertoli cells in testis of dogs without cryptorchidism. The AQP5 protein was not detected in germ cells but was present in Sertoli and Leydig cells and in endothelia of blood vessels. In cryptorchid dogs, AQP3 was detected in early-developing germ and Sertoli cells, and AQP5 had a distribution pattern similar to testes of dogs without cryptorchidism. In the epididymis, AQP3 and AQP5 were localised in epithelial cells of dogs with and without cryptorchidism in a cell-specific manner. The AQP3 and AQP5 protein was in larger abundance in the gonads from dogs with and without cryptorchidism. In contrast, AQP3 and AQP5 abundance increased in each segment of the cryptorchid epididymis, likely as a compensatory mechanism associated with the pathologic condition. These results indicate involvement of AQP3 and AQP5 in spermatogenesis and sperm maturation. Results from the present study indicate dogs are a useful for comparative reproductive biology studies.
Differential abundances of AQP3 and AQP5 in reproductive tissues from dogs with and without cryptorchidism
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Differential abundances of AQP3 and AQP5 in reproductive tissues from dogs with and without cryptorchidism
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Squillacioti C, Mirabella N, Liguori G, Germano G, Pelagalli A
* Aquaporins Are Differentially Regulated in Canine Cryptorchid Efferent Ductules and Epididymis (60 views)
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Impact Factor: 2.7
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Squillacioti C, Pelagalli A, De Luca A, Liguori G, Ali S, Mirabella N
* Urocortinergic system in the epididymis of the normal and cryptorchid dogs (228 views)
Reprod Domest Anim (ISSN: 0936-6768linking), 2019 Apr 20; N/D: N/D-N/D.
Impact Factor: 1.638
View Export to BibTeX Export to EndNote
* Aquaporins Are Differentially Regulated in Canine Cryptorchid Efferent Ductules and Epididymis (60 views)
Animals (ISSN: 2076-2615linking, 2076-2615electronic), 2021 May 25; 11(6): N/D-N/D.
Impact Factor: 2.7
View Export to BibTeX Export to EndNote
Squillacioti C, Pelagalli A, De Luca A, Liguori G, Ali S, Mirabella N
* Urocortinergic system in the epididymis of the normal and cryptorchid dogs (228 views)
Reprod Domest Anim (ISSN: 0936-6768linking), 2019 Apr 20; N/D: N/D-N/D.
Impact Factor: 1.638
View Export to BibTeX Export to EndNote
2 Records (2 excluding Abstracts).
Total impact factor: 4.338 (4.338 excluding Abstracts).
Total 5 year impact factor: 0 (0 excluding Abstracts).
Total impact factor: 4.338 (4.338 excluding Abstracts).
Total 5 year impact factor: 0 (0 excluding Abstracts).
41 views. Last view on Friday 31 May 2024, 23:19:04
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