Synthesis and Investigation of Physicochemical Properties and Biocompatibility of Phosphate-Vanadate Hydroxyapatite Co-Doped with Tb(3+) and Sr(2+) Ions

Searching for biocompatible materials with proper luminescent properties is of fundamental importance, as they can be applied in fluorescent labeling and regenerative medicine. In this study, we obtained new phosphate-vanadate hydroxyapatites (abbr. HVps) co-doped with Sr(2+) and Tb(3+) ions via the hydrothermal method. We focused on examining the effect of various annealing temperatures (500, 600 and 700 °C) on the spectroscopic properties and morphology of the obtained HVps. To characterize their morphology, XRPD (X-ray powder diffraction), SEM-EDS (scanning electron microscopy-energy-dispersive spectrometry), FT-IR (Fourier transform infrared) spectroscopy and ICP-OES (inductively coupled plasma-optical emission spectrometry) techniques were used. A further study of luminescent properties and cytocompatibility showed that the obtained HVps co-doped with Sr(2+) and Tb(3+) ions are highly biocompatible and able to enhance the proliferation process and can therefore be potentially used as fluorescent probes or in regenerative medicine.

Synthesis and Investigation of Physicochemical Properties and Biocompatibility of Phosphate-Vanadate Hydroxyapatite Co-Doped with Tb(3+) and Sr(2+) Ions

Query:  [X]
Options:	AnyAllExact    Extended      IBB affiliation
	ORAND
Authors:  [X]
Paper type:  [X]
Start date:  [X]
End date:  [X]
Site:	All sitesNaples - De AmicisNaples - CastellinoTurin
	StaffResearch areasActivitiesBibliographyPapersCMSGeneric [Clear form]