Advances in Amino Acid-based Chemistry (46 views)
Pharmaceuticals, 2023 Oct; 16: N/D-N/D.
Export to BibTeX Export to EndNote
Paper type: Editorial
Impact factor: 4.6, 5-year impact factor: 4.9
Url: https://www.mdpi.com/journal/pharmaceuticals
Keywords: Peptide, Synthesis, Nanomaterials, Therapeutics, Cosmetics, Vaccines, Nucleopeptide
Affiliations:
*** IBB - CNR ***
1 Institute of Biostructures and Bioimaging, Italian National Research Council (IBB-CNR), Via P. Castel-lino 111, 80131 Naples, Italy; rosanna.palumbo@cnr.it; giovanni.roviello@cnr.it 2 Yerevan State University, 1 Alex Manoogian Str., 0025 Yerevan, Armenia; hayarpi.simonyan@ysu.am * Correspondence: giovanni.roviello@cnr.it; Tel.: +390812203415
References:
Fik-Jaskółka, M. A.; Mkrtchyan, A. F.; Saghyan, A. S.; Palumbo, R.; Belter, A.; Hayriyan, L. A.; Simonyan, H.; Roviello, V.; Roviello, G. N., Spectroscopic and SEM evidences for G4-DNA binding by a synthetic alkyne-containing amino acid with anticancer activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2020, 229, 117884.
2. Vieira, A. D. C.; Medeiros, E. B.; Zabot, G. C.; de Souza Pereira, N.; do Nascimento, N. B.; Lidio, A. V.; Scheffer, Â. K.; Rempel, L. C. T.; Macarini, B. M. N.; de Aguiar Costa, M., Neuroprotective effects of combined therapy with memantine, donepezil, and vitamin D in ovariectomized female mice subjected to dementia model. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2023, 122, 110653.
3. Choi, S. H.; Tanzi, R. E., Adult neurogenesis in Alzheimer's disease. Hippocampus 2023, 33, (4), 307-321.
4. Wang, C.; Shao, S.; Li, N.; Zhang, Z.; Zhang, H.; Liu, B., Advances in Alzheimer’s Disease-Associated Aβ Therapy Based on Peptide. International Journal of Molecular Sciences 2023, 24, (17), 13110.
5. Cornelissen, F. M.; Markert, G.; Deutsch, G.; Antonara, M.; Faaij, N.; Bartelink, I.; Noske, D.; Vandertop, W. P.; Bender, A.; Westerman, B. A., Explaining Blood–Brain Barrier Permeability of Small Molecules by Integrated Analysis of Different Transport Mechanisms. Journal of Medicinal Chemistry 2023.
6. Yin, Y.; Liu, W.; Dai, Y., SOCS3 and its role in associated diseases. Human immunology 2015, 76, (10), 775-780.
7. Berishaj, M.; Gao, S. P.; Ahmed, S.; Leslie, K.; Al-Ahmadie, H.; Gerald, W. L.; Bornmann, W.; Bromberg, J. F., Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer. Breast Cancer Research 2007, 9, 1-8.
8. Fatima, G. N.; Fatma, H.; Saraf, S. K., Vaccines in Breast Cancer: Challenges and Breakthroughs. Diagnostics 2023, 13, (13), 2175.
9. Zhu, S.-Y.; Yu, K.-D., Breast cancer vaccines: disappointing or promising? Frontiers in Immunology 2022, 13, 828386.
10. Ghosh, S.; Ghosh, T.; Bhowmik, S.; Patidar, M. K.; Das, A. K., Nucleopeptide-coupled injectable bioconjugated guanosine-quadruplex hydrogel with inherent antibacterial activity. ACS Applied Bio Materials 2023, 6, (2), 640-651.
11. Hoschtettler, P.; Pickaert, G.; Carvalho, A.; Averlant-Petit, M.-C.; Stefan, L., Highly Synergistic Properties of Multicomponent Hydrogels Thanks to Cooperative Nucleopeptide Assemblies. Chemistry of Materials 2023.
12. Palumbo, R.; Omodei, D.; Vicidomini, C.; Roviello, G. N., Willardiine and its synthetic analogues: Biological aspects and implications in peptide chemistry of this nucleobase amino acid. Pharmaceuticals 2022, 15, (10), 1243.
13. Li, X.; Bian, S.; Zhao, M.; Han, X.; Liang, J.; Wang, K.; Jiang, Q.; Sun, Y.; Fan, Y.; Zhang, X., Stimuli-responsive biphenyl-tripeptide supramolecular hydrogels as biomimetic extracellular matrix scaffolds for cartilage tissue engineering. Acta Biomaterialia 2021, 131, 128-137.
14. Mazurowska, L.; Mojski, M., Biological activities of selected peptides: skin penetration ability of copper complexes with peptides. Journal of cosmetic science 2008, 59, (1), 59-69.
Pharmaceuticals, 2023 Oct; 16: N/D-N/D.
Export to BibTeX Export to EndNote
Paper type: Editorial
Impact factor: 4.6, 5-year impact factor: 4.9
Url: https://www.mdpi.com/journal/pharmaceuticals
Keywords: Peptide, Synthesis, Nanomaterials, Therapeutics, Cosmetics, Vaccines, Nucleopeptide
Affiliations:
*** IBB - CNR ***
1 Institute of Biostructures and Bioimaging, Italian National Research Council (IBB-CNR), Via P. Castel-lino 111, 80131 Naples, Italy; rosanna.palumbo@cnr.it; giovanni.roviello@cnr.it 2 Yerevan State University, 1 Alex Manoogian Str., 0025 Yerevan, Armenia; hayarpi.simonyan@ysu.am * Correspondence: giovanni.roviello@cnr.it; Tel.: +390812203415
References:
Fik-Jaskółka, M. A.; Mkrtchyan, A. F.; Saghyan, A. S.; Palumbo, R.; Belter, A.; Hayriyan, L. A.; Simonyan, H.; Roviello, V.; Roviello, G. N., Spectroscopic and SEM evidences for G4-DNA binding by a synthetic alkyne-containing amino acid with anticancer activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2020, 229, 117884.
2. Vieira, A. D. C.; Medeiros, E. B.; Zabot, G. C.; de Souza Pereira, N.; do Nascimento, N. B.; Lidio, A. V.; Scheffer, Â. K.; Rempel, L. C. T.; Macarini, B. M. N.; de Aguiar Costa, M., Neuroprotective effects of combined therapy with memantine, donepezil, and vitamin D in ovariectomized female mice subjected to dementia model. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2023, 122, 110653.
3. Choi, S. H.; Tanzi, R. E., Adult neurogenesis in Alzheimer's disease. Hippocampus 2023, 33, (4), 307-321.
4. Wang, C.; Shao, S.; Li, N.; Zhang, Z.; Zhang, H.; Liu, B., Advances in Alzheimer’s Disease-Associated Aβ Therapy Based on Peptide. International Journal of Molecular Sciences 2023, 24, (17), 13110.
5. Cornelissen, F. M.; Markert, G.; Deutsch, G.; Antonara, M.; Faaij, N.; Bartelink, I.; Noske, D.; Vandertop, W. P.; Bender, A.; Westerman, B. A., Explaining Blood–Brain Barrier Permeability of Small Molecules by Integrated Analysis of Different Transport Mechanisms. Journal of Medicinal Chemistry 2023.
6. Yin, Y.; Liu, W.; Dai, Y., SOCS3 and its role in associated diseases. Human immunology 2015, 76, (10), 775-780.
7. Berishaj, M.; Gao, S. P.; Ahmed, S.; Leslie, K.; Al-Ahmadie, H.; Gerald, W. L.; Bornmann, W.; Bromberg, J. F., Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer. Breast Cancer Research 2007, 9, 1-8.
8. Fatima, G. N.; Fatma, H.; Saraf, S. K., Vaccines in Breast Cancer: Challenges and Breakthroughs. Diagnostics 2023, 13, (13), 2175.
9. Zhu, S.-Y.; Yu, K.-D., Breast cancer vaccines: disappointing or promising? Frontiers in Immunology 2022, 13, 828386.
10. Ghosh, S.; Ghosh, T.; Bhowmik, S.; Patidar, M. K.; Das, A. K., Nucleopeptide-coupled injectable bioconjugated guanosine-quadruplex hydrogel with inherent antibacterial activity. ACS Applied Bio Materials 2023, 6, (2), 640-651.
11. Hoschtettler, P.; Pickaert, G.; Carvalho, A.; Averlant-Petit, M.-C.; Stefan, L., Highly Synergistic Properties of Multicomponent Hydrogels Thanks to Cooperative Nucleopeptide Assemblies. Chemistry of Materials 2023.
12. Palumbo, R.; Omodei, D.; Vicidomini, C.; Roviello, G. N., Willardiine and its synthetic analogues: Biological aspects and implications in peptide chemistry of this nucleobase amino acid. Pharmaceuticals 2022, 15, (10), 1243.
13. Li, X.; Bian, S.; Zhao, M.; Han, X.; Liang, J.; Wang, K.; Jiang, Q.; Sun, Y.; Fan, Y.; Zhang, X., Stimuli-responsive biphenyl-tripeptide supramolecular hydrogels as biomimetic extracellular matrix scaffolds for cartilage tissue engineering. Acta Biomaterialia 2021, 131, 128-137.
14. Mazurowska, L.; Mojski, M., Biological activities of selected peptides: skin penetration ability of copper complexes with peptides. Journal of cosmetic science 2008, 59, (1), 59-69.
Advances in Amino Acid-based Chemistry
Peptide-based therapies are of great importance in biomedicine for the treatment of pathologies with enormous societal impact, including cancer, neurodegeneration, and viral diseases, such as the COVID-19. Peptides can interact with biological macromolecules involved in important bi-ological pathways such as proteins and nucleic acids. Furthermore, once functionalized by DNA nucleic bases, they become powerful tools for targeting DNA and RNA, as evidenced by the sci-entific literature on peptide nucleic acids and nucleopeptides, endowed with a huge diagnostic and therapeutic potential. Moreover, peptide analogs of a different nature, with self-assembly properties leading to supramolecular assemblies and nanocomposites, are attracting increasing attention in nanomedicine and biotechnology. Peptides find also application in vaccines and cosmetics for sensitive skins. Herein, we focus on novel strategies using amino acid-derivatives and peptides whose development can improve the overall knowledge of amino acid-based chemistry at the interface between nanotechnology and human health-oriented applications.
Peptide-based therapies are of great importance in biomedicine for the treatment of pathologies with enormous societal impact, including cancer, neurodegeneration, and viral diseases, such as the COVID-19. Peptides can interact with biological macromolecules involved in important bi-ological pathways such as proteins and nucleic acids. Furthermore, once functionalized by DNA nucleic bases, they become powerful tools for targeting DNA and RNA, as evidenced by the sci-entific literature on peptide nucleic acids and nucleopeptides, endowed with a huge diagnostic and therapeutic potential. Moreover, peptide analogs of a different nature, with self-assembly properties leading to supramolecular assemblies and nanocomposites, are attracting increasing attention in nanomedicine and biotechnology. Peptides find also application in vaccines and cosmetics for sensitive skins. Herein, we focus on novel strategies using amino acid-derivatives and peptides whose development can improve the overall knowledge of amino acid-based chemistry at the interface between nanotechnology and human health-oriented applications.
Advances in Amino Acid-based Chemistry
Advances in Amino Acid-based Chemistry
Other filter: ([btitle,keywords] "Nanomaterials" OR [b ...
Scognamiglio PL, Vicidomini C, Roviello GN
* Dancing with Nucleobases: Unveiling the Self-Assembly Properties of DNA and RNA Base-Containing Molecules for Gel Formation (72 views)
Gels, 2023 Dec 23; 10: 16-16.
Impact Factor: 4.6
View Export to BibTeX Export to EndNote
Palumbo R, Simonyan H, Roviello GN
* Advances in Amino Acid-based Chemistry (28 views)
Pharmaceuticals, 2023 Oct; 16: 1490-1492.
Impact Factor: 4.6
View Export to BibTeX Export to EndNote
Palumbo R, Omodei D, Vicidomini C, Roviello GN
* Willardiine and Its Synthetic Analogues: Biological Aspects and Implications in Peptide Chemistry of This Nucleobase Amino Acid (41 views)
Pharmaceuticals, 2022 Oct 10; 15: 1243-1243.
Impact Factor: 5.2
View Export to BibTeX Export to EndNote
Musumeci D, Ullah S, Ikram A, Roviello GN
* Novel insights on nucleopeptide binding: a spectroscopic and in silico investigation on the interaction of a thymine-bearing tetrapeptide with a homoadenine DNA (196 views)
Journal Of Molecular Liquids, 2021 Dec; 117975: 14140-14148.
Impact Factor: 6.165
View Export to BibTeX Export to EndNote
Roviello V, Roviello GN
* Less COVID-19 deaths in southern and insular Italy explained by forest bathing, Mediterranean environment, and antiviral plant volatile organic compounds (72 views)
Environ Chem Lett (ISSN: 1610-3653linking), 2021 Nov; N/D: 1-11.
Impact Factor: 9.027
View Export to BibTeX Export to EndNote
La Manna S, Lopez-sanz L, Bernal S, Fortuna S, Mercurio FA, Leone M, Gomez-guerrero C, Marasco D
* Cyclic mimetics of kinase-inhibitory region of Suppressors of Cytokine Signaling 1: Progress toward novel anti-inflammatory therapeutics (146 views)
Eur J Med Chem (ISSN: 0223-5234linking, 1768-3254, 1768-3254electronic), 2021 Oct 5; 221: 113547-113547.
Impact Factor: 5.572
View Export to BibTeX Export to EndNote
Roviello V, Musumeci D, Mokhir A, Roviello GN
* Evidence of Protein Binding by a Nucleopeptide Based on a Thyminedecorated L-Diaminopropanoic Acid through CD and In Silico Studies (140 views) (PDF 27 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021 Jul; 28(24): 5004-5015.
Impact Factor: 4.53
View Export to BibTeX Export to EndNote
Scognamiglio PL, Platella C, Napolitano E, Musumeci D, Roviello GN
* From Prebiotic Chemistry to Supramolecular Biomedical Materials: Exploring the Properties of Self-Assembling Nucleobase-Containing Peptides (149 views)
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Jun 10; 26(12): 3558-3558.
Impact Factor: 4.411
View Export to BibTeX Export to EndNote
Riccardi C, Napolitano E, Platella C, Musumeci D, Melone MAB, Montesarchio D
* Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics (84 views)
Med Res Rev (ISSN: 0198-6325linking, 1098-1128electronic), 2021 Jan; 41(1): 464-506.
Impact Factor: 9.3
View Export to BibTeX Export to EndNote
Roviello V, Roviello GN
* Lower COVID-19 mortality in Italian forested areas suggests immunoprotection by Mediterranean plants (331 views)
Environ Chem Lett (ISSN: 1610-3653linking), 2021 Jan; 19: 699-710.
Impact Factor: 9.027
View Export to BibTeX Export to EndNote
Sivaccumar J, Sandomenico A, Vitagliano L, Ruvo M
* Monoclonal Antibodies: A Prospective and Retrospective View (182 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021; 28(3): 435-471.
Impact Factor: 4.184
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Musumeci D, Mokhir A, Roviello GN
* Synthesis and nucleic acid binding evaluation of a thyminyl L-diaminobutanoic acid-based nucleopeptide (200 views)
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2020 Jul; 100: 103862-103870.
Impact Factor: 4.831
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Doti N, Caporale A, Monti A, Sandomenico A, Selis F, Ruvo M
* A recent update on the use of microbial transglutaminase for the generation of biotherapeutics (162 views)
World J Microbiol Biotechnol (ISSN: 0959-3993linking), 2020 Mar 14; 36(4): 53-53.
Impact Factor: 2.477
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Musumeci D, Roviello V, Roviello GN
* DNA- and RNA-binding ability of oligoDapT, a nucleobase-decorated peptide, for biomedical applications (2360 views)
Int J Nanomed (ISSN: 1176-9114linking, 1178-2013electronic), 2018 May 1; 2018:13: 2613-2629.
Impact Factor: 4.3
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Squeglia F, Ruggiero A, De Simone A, Berisio R
* A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics (305 views)
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Feb; 27(2): 369-380.
Impact Factor: 2.523
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Oliveri V, Zimbone S, Giuffrida ML, Bellia F, Tomasello MF, Vecchio G
* Porphyrin Cyclodextrin Conjugates Modulate Amyloid Beta Peptide Aggregation and Cytotoxicity (660 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(24): 6349-6353.
Impact Factor: 5.476
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Pirtskhalava M, Egoyan A, Mirtskhulava M, Roviello GN
* A COMPUTER MODELING STUDY OF BINDING PROPERTIES OF CHIRAL NUCLEOPEPTIDE FOR BIOMEDICAL APPLICATIONS (487 views)
Georgian Med News (ISSN: 1512-0112print, 1512-0112linking), 2017 Dec; (273): 1123-1128.
Impact Factor: 0
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Camorani S, Hill BS, Fontanella R, Greco A, Gramanzini M, Auletta L, Gargiulo S, Albanese S, Lucarelli E, Cerchia L, Zannetti A
* Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRbeta Aptamer (780 views) (PDF 227 views)
Theranostics (ISSN: 1838-7640, 1838-7640electronic), 2017 Aug 22; 7(14): 3595-3607.
Impact Factor: 8.537
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D’andrea LD, De Rosa L, Vigliotti C, Cataldi M
* VEGF mimetic peptides: potential applications in central nervous system therapeutics (580 views)
New Horizons In Translational Medicine, 2017; 233: 225-225.
Impact Factor: 0
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D'Andrea LD, Rosa LD, Vigliotti C, Cataldi M
* VEGF mimic peptides: Potential applications in central nervous system therapeutics (955 views)
New Horizons Transl Med (ISSN: 2307-5023), 2017; 3(5): 233-251.
Impact Factor: 0
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Roviello GN, Musumeci D
* Synthetic approaches to nucleopeptides containing all the four nucleobases, and nucleic acid-binding studies on a mixed-sequence nucleo-oligolysine (583 views)
Rsc Adv (ISSN: 2046-2069, 2046-2069electronic), 2016 Jun; 6: 63578-63585.
Impact Factor: 3.108
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Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (590 views)
Rsc Adv (ISSN: 2046-2069, 2046-2069electronic), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
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Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
* CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics (588 views)
Medchemcomm (ISSN: 2040-2503), 2015; 6(1): 155-163.
Impact Factor: 2.319
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Roviello GN, Musumeci D, Roviello V, Pirtskhalava M, Egoyan A, Mirtskhulava M
* Natural and artificial binders of polyriboadenylic acid and their effect on RNA structure (496 views)
Beilstein J Nanotech (ISSN: 2190-4286), 2015; 6(1): 1338-1347.
Impact Factor: 2.778
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Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Binding ability of a thymine-functionalized oligolysine towards nucleic acids (401 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2014 Feb 1; 22(3): 997-1002.
Impact Factor: 2.793
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Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Synthesis of a thymine-functionalized nucleoamino acid for the solid phase assembly of cationic nucleopeptides (602 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2013 Oct; 45(4): 779-784.
Impact Factor: 3.653
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (561 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
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Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (629 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (621 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Evidences for supramolecular organization of nucleopeptides: Synthesis, spectroscopic and biological studies of a novel dithymine l-serine tetrapeptide (720 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 Apr; 7(4): 1073-1080.
Impact Factor: 3.534
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Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (512 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
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Roviello GN, Benedetti E, Pedone C, Bucci EM
* Nucleobase-containing peptides: An overview of their characteristic features and applications (998 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jun; 39(1): 45-57.
Impact Factor: 4.106
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Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (545 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
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Roviello GN, Musumeci D, Pedone C, Bucci EM
* Synthesis, Characterization And Hybridization Studies Of An Alternate Nucleo-Epsilon/Gamma-Peptide: Complexes Formation With Natural Nucleic Acids (699 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jan; 38(1): 103-111.
Impact Factor: 4.106
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Accardo A, Tesauro D, Aloj L, Tarallo L, Arra C, Mangiapia G, Vaccaro M, Pedone C, Paduano L, Morelli G
* Peptide-containing aggregates as selective nanocarriers for therapeutics (476 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2008 Apr; 3(4): 594-602.
Impact Factor: 3.15
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Roviello GN, Musumeci D, Moccia M, Castiglione M, Sapio R, Valente M, Bucci EM, Perretta G, Pedone C
* Dabpna: Design, Synthesis And Nucleic Acids Binding Studies (496 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1307-1310.
Impact Factor: 0.723
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Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (610 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
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* Dancing with Nucleobases: Unveiling the Self-Assembly Properties of DNA and RNA Base-Containing Molecules for Gel Formation (72 views)
Gels, 2023 Dec 23; 10: 16-16.
Impact Factor: 4.6
View Export to BibTeX Export to EndNote
Palumbo R, Simonyan H, Roviello GN
* Advances in Amino Acid-based Chemistry (28 views)
Pharmaceuticals, 2023 Oct; 16: 1490-1492.
Impact Factor: 4.6
View Export to BibTeX Export to EndNote
Palumbo R, Omodei D, Vicidomini C, Roviello GN
* Willardiine and Its Synthetic Analogues: Biological Aspects and Implications in Peptide Chemistry of This Nucleobase Amino Acid (41 views)
Pharmaceuticals, 2022 Oct 10; 15: 1243-1243.
Impact Factor: 5.2
View Export to BibTeX Export to EndNote
Musumeci D, Ullah S, Ikram A, Roviello GN
* Novel insights on nucleopeptide binding: a spectroscopic and in silico investigation on the interaction of a thymine-bearing tetrapeptide with a homoadenine DNA (196 views)
Journal Of Molecular Liquids, 2021 Dec; 117975: 14140-14148.
Impact Factor: 6.165
View Export to BibTeX Export to EndNote
Roviello V, Roviello GN
* Less COVID-19 deaths in southern and insular Italy explained by forest bathing, Mediterranean environment, and antiviral plant volatile organic compounds (72 views)
Environ Chem Lett (ISSN: 1610-3653linking), 2021 Nov; N/D: 1-11.
Impact Factor: 9.027
View Export to BibTeX Export to EndNote
La Manna S, Lopez-sanz L, Bernal S, Fortuna S, Mercurio FA, Leone M, Gomez-guerrero C, Marasco D
* Cyclic mimetics of kinase-inhibitory region of Suppressors of Cytokine Signaling 1: Progress toward novel anti-inflammatory therapeutics (146 views)
Eur J Med Chem (ISSN: 0223-5234linking, 1768-3254, 1768-3254electronic), 2021 Oct 5; 221: 113547-113547.
Impact Factor: 5.572
View Export to BibTeX Export to EndNote
Roviello V, Musumeci D, Mokhir A, Roviello GN
* Evidence of Protein Binding by a Nucleopeptide Based on a Thyminedecorated L-Diaminopropanoic Acid through CD and In Silico Studies (140 views) (PDF 27 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021 Jul; 28(24): 5004-5015.
Impact Factor: 4.53
View Export to BibTeX Export to EndNote
Scognamiglio PL, Platella C, Napolitano E, Musumeci D, Roviello GN
* From Prebiotic Chemistry to Supramolecular Biomedical Materials: Exploring the Properties of Self-Assembling Nucleobase-Containing Peptides (149 views)
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Jun 10; 26(12): 3558-3558.
Impact Factor: 4.411
View Export to BibTeX Export to EndNote
Riccardi C, Napolitano E, Platella C, Musumeci D, Melone MAB, Montesarchio D
* Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics (84 views)
Med Res Rev (ISSN: 0198-6325linking, 1098-1128electronic), 2021 Jan; 41(1): 464-506.
Impact Factor: 9.3
View Export to BibTeX Export to EndNote
Roviello V, Roviello GN
* Lower COVID-19 mortality in Italian forested areas suggests immunoprotection by Mediterranean plants (331 views)
Environ Chem Lett (ISSN: 1610-3653linking), 2021 Jan; 19: 699-710.
Impact Factor: 9.027
View Export to BibTeX Export to EndNote
Sivaccumar J, Sandomenico A, Vitagliano L, Ruvo M
* Monoclonal Antibodies: A Prospective and Retrospective View (182 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021; 28(3): 435-471.
Impact Factor: 4.184
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Musumeci D, Mokhir A, Roviello GN
* Synthesis and nucleic acid binding evaluation of a thyminyl L-diaminobutanoic acid-based nucleopeptide (200 views)
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2020 Jul; 100: 103862-103870.
Impact Factor: 4.831
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Doti N, Caporale A, Monti A, Sandomenico A, Selis F, Ruvo M
* A recent update on the use of microbial transglutaminase for the generation of biotherapeutics (162 views)
World J Microbiol Biotechnol (ISSN: 0959-3993linking), 2020 Mar 14; 36(4): 53-53.
Impact Factor: 2.477
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Musumeci D, Roviello V, Roviello GN
* DNA- and RNA-binding ability of oligoDapT, a nucleobase-decorated peptide, for biomedical applications (2360 views)
Int J Nanomed (ISSN: 1176-9114linking, 1178-2013electronic), 2018 May 1; 2018:13: 2613-2629.
Impact Factor: 4.3
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Squeglia F, Ruggiero A, De Simone A, Berisio R
* A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics (305 views)
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Feb; 27(2): 369-380.
Impact Factor: 2.523
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Oliveri V, Zimbone S, Giuffrida ML, Bellia F, Tomasello MF, Vecchio G
* Porphyrin Cyclodextrin Conjugates Modulate Amyloid Beta Peptide Aggregation and Cytotoxicity (660 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(24): 6349-6353.
Impact Factor: 5.476
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Pirtskhalava M, Egoyan A, Mirtskhulava M, Roviello GN
* A COMPUTER MODELING STUDY OF BINDING PROPERTIES OF CHIRAL NUCLEOPEPTIDE FOR BIOMEDICAL APPLICATIONS (487 views)
Georgian Med News (ISSN: 1512-0112print, 1512-0112linking), 2017 Dec; (273): 1123-1128.
Impact Factor: 0
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Camorani S, Hill BS, Fontanella R, Greco A, Gramanzini M, Auletta L, Gargiulo S, Albanese S, Lucarelli E, Cerchia L, Zannetti A
* Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRbeta Aptamer (780 views) (PDF 227 views)
Theranostics (ISSN: 1838-7640, 1838-7640electronic), 2017 Aug 22; 7(14): 3595-3607.
Impact Factor: 8.537
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D’andrea LD, De Rosa L, Vigliotti C, Cataldi M
* VEGF mimetic peptides: potential applications in central nervous system therapeutics (580 views)
New Horizons In Translational Medicine, 2017; 233: 225-225.
Impact Factor: 0
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D'Andrea LD, Rosa LD, Vigliotti C, Cataldi M
* VEGF mimic peptides: Potential applications in central nervous system therapeutics (955 views)
New Horizons Transl Med (ISSN: 2307-5023), 2017; 3(5): 233-251.
Impact Factor: 0
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Roviello GN, Musumeci D
* Synthetic approaches to nucleopeptides containing all the four nucleobases, and nucleic acid-binding studies on a mixed-sequence nucleo-oligolysine (583 views)
Rsc Adv (ISSN: 2046-2069, 2046-2069electronic), 2016 Jun; 6: 63578-63585.
Impact Factor: 3.108
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Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (590 views)
Rsc Adv (ISSN: 2046-2069, 2046-2069electronic), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
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Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
* CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics (588 views)
Medchemcomm (ISSN: 2040-2503), 2015; 6(1): 155-163.
Impact Factor: 2.319
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Roviello GN, Musumeci D, Roviello V, Pirtskhalava M, Egoyan A, Mirtskhulava M
* Natural and artificial binders of polyriboadenylic acid and their effect on RNA structure (496 views)
Beilstein J Nanotech (ISSN: 2190-4286), 2015; 6(1): 1338-1347.
Impact Factor: 2.778
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Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Binding ability of a thymine-functionalized oligolysine towards nucleic acids (401 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2014 Feb 1; 22(3): 997-1002.
Impact Factor: 2.793
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Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Synthesis of a thymine-functionalized nucleoamino acid for the solid phase assembly of cationic nucleopeptides (602 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2013 Oct; 45(4): 779-784.
Impact Factor: 3.653
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (561 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
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Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (629 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (621 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Evidences for supramolecular organization of nucleopeptides: Synthesis, spectroscopic and biological studies of a novel dithymine l-serine tetrapeptide (720 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 Apr; 7(4): 1073-1080.
Impact Factor: 3.534
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Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (512 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
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Roviello GN, Benedetti E, Pedone C, Bucci EM
* Nucleobase-containing peptides: An overview of their characteristic features and applications (998 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jun; 39(1): 45-57.
Impact Factor: 4.106
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Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (545 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
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Roviello GN, Musumeci D, Pedone C, Bucci EM
* Synthesis, Characterization And Hybridization Studies Of An Alternate Nucleo-Epsilon/Gamma-Peptide: Complexes Formation With Natural Nucleic Acids (699 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jan; 38(1): 103-111.
Impact Factor: 4.106
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Accardo A, Tesauro D, Aloj L, Tarallo L, Arra C, Mangiapia G, Vaccaro M, Pedone C, Paduano L, Morelli G
* Peptide-containing aggregates as selective nanocarriers for therapeutics (476 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2008 Apr; 3(4): 594-602.
Impact Factor: 3.15
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Roviello GN, Musumeci D, Moccia M, Castiglione M, Sapio R, Valente M, Bucci EM, Perretta G, Pedone C
* Dabpna: Design, Synthesis And Nucleic Acids Binding Studies (496 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1307-1310.
Impact Factor: 0.723
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Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (610 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
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37 Records (37 excluding Abstracts).
Total impact factor: 149.329 (149.329 excluding Abstracts).
Total 5 year impact factor: 133.471 (133.471 excluding Abstracts).
Total impact factor: 149.329 (149.329 excluding Abstracts).
Total 5 year impact factor: 133.471 (133.471 excluding Abstracts).
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