Cell recruitment and transfection in gene activated collagen matrix (381 views)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2010 Jan; 31(3): 570-576.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 7.883, 5-year impact factor: 9.076
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-70449134628&partnerID=40&md5=9f08ebdda4ae3c1b8d880885059f6967
Keywords: Cell Migration, Cell Recruitment, Collagen, Dna Complexes Immobilization, Gene Activated Matrices, Non Viral Gene Delivery, Cell Transfection, Collagen Matrices, Control Of Gene Expression, Encoded Proteins, Gene-Activated Matrix, In-Vivo, New Approaches, Polyethylenimines, Time-Lapse Video Microscopy, Tissue Regeneration, Tissue Repair, Transfected Cells, Cytology, Employment, Fluorescence Microscopy, Gene Transfer, Nucleic Acids, Three Dimensional, Cell Immobilization, Avidin, Polyethyleneimine, Animal Cell, Article, Biotinylation, Cell Strain 3t3, Complex Formation, Conjugation, Controlled Study, Embryo, Fluorescence Activated Cell Sorting, Gene Activation, Gene Expression Regulation, Gene Targeting, Genetic Transfection, Internalization, Microenvironment, Mouse, Nonhuman, Priority Journal, Protein Modification, Cell Movement, Extracellular Matrix, Materials Testing, Molecular Structure, Nih 3t3 Cells, Spectrometry, Electrospray Ionization,
Affiliations:
*** IBB - CNR ***
Department of Materials and Production Engineering, University of Naples Federico II, Piazzale Tecchio 80, Naples, 80125, Italy
Interdisciplinary Research Centre on Biomaterials (CRIB), Italian Institute of Technology, IIT, Piazzale Tecchio 80, Naples, 80125, Italy
Department of Biological Science, section Biostructures, University of Naples Federico II, via Mezzocannone 16, Naples, 80134, Italy
References:
Cukierman, E., Pankov, R., Yamada, K.M., Cell interactions with three-dimensional matrices (2002) Curr Opin Cell Biol, 14, pp. 633-63
Kleinman, H.K., Ohilp, D., Hoffman, M.P., Role of the extracellular matrix in morphogenesis (2003) Curr Opin Biotechnol, 14, pp. 526-532
Schmeichel, K.L., Bissell, M.J., Modeling tissue-specific signalling and organ function in three dimensions (2003) J Cell Sci, 116, pp. 2377-2388
Peppas, N.A., Langer, R., New challenge in biomaterials (1994) Science, 263, pp. 1715-1720
Hubbell, J.A., Biomaterials in tissue engineering (1995) Biotechnology, 13 (6), pp. 565-576
Langer, R., Tirrell, D.A., Designing materials for biology and medicine (2004) Nature, 428, pp. 487-492
Lutolf, M.P., Hubbell, J.A., Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering (2005) Nat Biotechnol, 23, pp. 47-55
Hubbell, J.A., Matrix bound growth factors in tissue repair (2006) Swiss Med Wkly, 136, pp. 387-391
Lu, Y., Shansky, J., Del, T.M., Ferland, P., Wang, X., Vandenburgh, H., Recombinant vascular endothelial growth factor secreted from tissue engineered bioartificial muscles promotes localized angiogenesis (2001) Circulation, 104, pp. 594-599
Savarino, L., Baldini, N., Greco, M., Capitani, O., Pinna, S., Valentini, S., The performance of poly-epsiloncaprolacton scaffolds in a rabbit femur model with and without autologous stromal cells and BMP4 (2007) Biomaterials, 28, pp. 3101-3109
Shen, H., Tan, J., Saltzman, W.M., Surface-mediated gene transfer from nanocomposites of controlled texture (2004) Nat Mater, 3, pp. 569-574
Panyam, J., Zhou, W., Prabha, S., Sahoo, S.K., Labhasetwar, V., Rapid endo-lysosomal escape of poly(dl-lactide-co-glycolide) nanoparticles: implication for drug and gene delivery (2002) FASEB J, 16, pp. 1217-1226
Pannier, A.K., Shea, L.D., Controlled release systems for DNA delivery (2004) Mol Ther, 10 (1), pp. 19-24
Fang, J., Zhu, Y.Y., Bonadio, J., Rouleau, J., Goldstein, S., McCauley, L.K., Stimulation of new bone formation by direct transfer of osteogenic plasmid genes (1996) Proc Natl Acad Sci U S A, 93, pp. 5753-5759
Bonadio, J., Smiley, E., Patil, P., Goldstein, S., Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration (1999) Nat Med, 5, pp. 753-759
Bonadio, J., Goldstein, S.A., Levy, R.S., Gene therapy for tissue repair and regeneration (1998) Adv Drug Deliv Rev, 33, pp. 53-69
Shea, L.D., Smiley, E., Bonadio, J., Mooney, D.J., DNA delivery from polymer matrices for tissue engineering (1999) Nat Biotechnol, 17 (6), pp. 551-554
Bonadio, J., Tissue engineering via local gene delivery: Update and future prospects for enhancing the technology (2000) Adv Drug Deliv Rev, 44, pp. 185-194
Endo, M., Kuroda, S., Kondo, H., Maruoka, Y., Ohya, K., Kasugai, S., Bone regeneration by modified gene-activated matrix: effectiveness in segmental tibial defects in rats (2006) Tissue Eng, 12 (3), pp. 489-497
Guo, T., Zhao, J., Chang, J., Ding, Z., Hong, H., Chen, J., Porous chitosan-gelatin scaffold containing plasmid DNA encoding transforming growth factor-beta1 for chondrocytes proliferation (2006) Biomaterials, 27 (7), pp. 1095-1103
Chandler, L.A., Gu, D.L., Ma, C., Gonzalez, A.M., Doukas, J., Nguyen, T., Matrix-enabled gene transfer for cutaneous wound repair (2000) Wound Repair Regen, 8 (6), pp. 473-479
Segura, T., Chung, P.H., Shea, L.D., DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach (2005) Biomaterials, 26, pp. 1575-1584
Lau, Y.K., Gobin, A.M., West, J.L., Overexpression of lysyl oxidase to increase matrix crosslinking and improve tissue strength in dermal wound healing (2006) Ann Biomed Eng, 34, pp. 1239-1246
Peng, L., Cheng, X., Zhuo, R., Lan, J., Wang, Y., Shi, B., Novel gene-activated matrix with embedded chitosan/plasmid DNA nanoparticles encoding PDGF for periodontal tissue engineering (2009) J Biomed Mater Res A, 90 (2), pp. 564-576
Cao, L., Mooney, D.J., Spatiotemporal control over growth factor signaling for therapeutic neovascularization (2007) Adv Drug Deliv Rev, 59 (13), pp. 1340-1350
DeLong, S.A., Gobin, A.S., West, J.L., Covalent immobilization of RGDS on hydrogel surfaces to direct cell alignment and migration (2005) J Control Release, 109 (1-3), pp. 139-148
DeLong, S.A., Moon, J.J., West, J.L., Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration (2005) Biomaterials, 26, pp. 3227-3234
Boyden, S., The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes (1962) J Exp Med, 115, pp. 453-466
Nelson, R.D., Quie, P.G., Simmons, R.L., Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leucocytes and monocytes (1975) J Immunol, 115, pp. 1650-1656
Moghe, P.V., Nelson, R.D., Tranquillo, R.T., Cytokine-stimulated chemotaxis of human neutrophils in a 3-D conjoined fibrin gel assay (1995) J Immunol Methods, 180, pp. 193-211
Knapp, D.M., Helou, E.F., Tranquillo, R.T., A fibrin or collagen gel assay for tissue cell chemotaxis: assessment of fibroblast chemotaxis to RGDSP (1999) Exp Cell Res, 247, pp. 543-553
Kipper, M.J., Kleinman, H.K., Wang, F.W., New method for modeling connective-tissue cell migration: improved accuracy on motility parameters (2007) Biophys J, 93 (5), pp. 1797-1808
Maheshwari, G., Lauffenburger, D.A., Deconstructing (and reconstructing) cell migration (1998) Microsc Res Tech, 43, pp. 358-368
Distasi, C., Ariano, P., Zamburlin, P., Ferraro, M., In vitro analysis of neuron-glial cell interactions during cellular migration (2002) Eur Biophys J, 31, pp. 81-88
Smith, J.T., Tomfohr, J.K., Wells, M.C., Beebe, T.P., Kepler, T.B., Reichert, W.M., Measurement of cell migration on surface-bound fibronectin gradients (2004) Langmuir, 20, pp. 8279-8286
Myles, J.L., Burgess, B.T., Dickinson, R.B., Modification of the adhesive properties of collagen by covalent grafting with RGD peptides (2000) J Biomater Sci Polym Ed, 11, pp. 69-86
De Rosa, E., Urciuolo, F., Borselli, C., Gerbasio, D., Imparato, G., Netti, P.A., Time and space evolution of transport properties in agarose-chondrocyte constructs (2006) Tissue Eng, 12, pp. 2193-2201
Stokes, C.L., Lauffenburger, D.A., Williams, S.K., Migration of individual microvessel endothelial cells: stochastic model and parameter measurement (1991) J Cell Sci, 99, pp. 419-430
Jang, J.H., Houchin, T.L., Shea, L.D., Gene delivery from polymeric scaffolds for tissue engineering (2004) Expert Rev Med Devices, 1 (1), pp. 127-138
Nishimura, I., Garrell, R., Hedrick, M., Iida, K., Osher, S., Wu, B., Precursor tissue analogs as a tissue-engineering strategy (2003) Tissue Eng, 9 (1), pp. 77-89
Tranquillo, R.T., Self-organization of tissue-equivalents: the nature and role of contact guidance (1999) Biochem Soc Symp, 65, pp. 27-47
Segura, T., Volk, M.J., Shea, L.D., Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification (2003) J Control Release, 93 (1), pp. 69-84
Hagstrom, J.E., Self-assembling complexes for in vivo gene delivery (2000) Curr Opin Mol Ther, 2 (2), pp. 143-149
Schaffer, D.V., Fidelman, N.A., Dan, N., Lauffenberger, D.A., Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery (2000) Biotechnol Bioeng, 67 (5), pp. 598-606
Kleinman, H. K., Ohilp, D., Hoffman, M. P., Role of the extracellular matrix in morphogenesis (2003) Curr Opin Biotechnol, 14, pp. 526-532
Schmeichel, K. L., Bissell, M. J., Modeling tissue-specific signalling and organ function in three dimensions (2003) J Cell Sci, 116, pp. 2377-2388
Peppas, N. A., Langer, R., New challenge in biomaterials (1994) Science, 263, pp. 1715-1720
Hubbell, J. A., Biomaterials in tissue engineering (1995) Biotechnology, 13 (6), pp. 565-576
Lutolf, M. P., Hubbell, J. A., Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering (2005) Nat Biotechnol, 23, pp. 47-55
Hubbell, J. A., Matrix bound growth factors in tissue repair (2006) Swiss Med Wkly, 136, pp. 387-391
Pannier, A. K., Shea, L. D., Controlled release systems for DNA delivery (2004) Mol Ther, 10 (1), pp. 19-24
Fang, J., Zhu, Y. Y., Bonadio, J., Rouleau, J., Goldstein, S., McCauley, L. K., Stimulation of new bone formation by direct transfer of osteogenic plasmid genes (1996) Proc Natl Acad Sci U S A, 93, pp. 5753-5759
Shea, L. D., Smiley, E., Bonadio, J., Mooney, D. J., DNA delivery from polymer matrices for tissue engineering (1999) Nat Biotechnol, 17 (6), pp. 551-554
Chandler, L. A., Gu, D. L., Ma, C., Gonzalez, A. M., Doukas, J., Nguyen, T., Matrix-enabled gene transfer for cutaneous wound repair (2000) Wound Repair Regen, 8 (6), pp. 473-479
Lau, Y. K., Gobin, A. M., West, J. L., Overexpression of lysyl oxidase to increase matrix crosslinking and improve tissue strength in dermal wound healing (2006) Ann Biomed Eng, 34, pp. 1239-1246
DeLong, S. A., Gobin, A. S., West, J. L., Covalent immobilization of RGDS on hydrogel surfaces to direct cell alignment and migration (2005) J Control Release, 109 (1-3), pp. 139-148
DeLong, S. A., Moon, J. J., West, J. L., Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration (2005) Biomaterials, 26, pp. 3227-3234
Nelson, R. D., Quie, P. G., Simmons, R. L., Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leucocytes and monocytes (1975) J Immunol, 115, pp. 1650-1656
Moghe, P. V., Nelson, R. D., Tranquillo, R. T., Cytokine-stimulated chemotaxis of human neutrophils in a 3-D conjoined fibrin gel assay (1995) J Immunol Methods, 180, pp. 193-211
Knapp, D. M., Helou, E. F., Tranquillo, R. T., A fibrin or collagen gel assay for tissue cell chemotaxis: assessment of fibroblast chemotaxis to RGDSP (1999) Exp Cell Res, 247, pp. 543-553
Kipper, M. J., Kleinman, H. K., Wang, F. W., New method for modeling connective-tissue cell migration: improved accuracy on motility parameters (2007) Biophys J, 93 (5), pp. 1797-1808
Smith, J. T., Tomfohr, J. K., Wells, M. C., Beebe, T. P., Kepler, T. B., Reichert, W. M., Measurement of cell migration on surface-bound fibronectin gradients (2004) Langmuir, 20, pp. 8279-8286
Myles, J. L., Burgess, B. T., Dickinson, R. B., Modification of the adhesive properties of collagen by covalent grafting with RGD peptides (2000) J Biomater Sci Polym Ed, 11, pp. 69-86
Stokes, C. L., Lauffenburger, D. A., Williams, S. K., Migration of individual microvessel endothelial cells: stochastic model and parameter measurement (1991) J Cell Sci, 99, pp. 419-430
Jang, J. H., Houchin, T. L., Shea, L. D., Gene delivery from polymeric scaffolds for tissue engineering (2004) Expert Rev Med Devices, 1 (1), pp. 127-138
Tranquillo, R. T., Self-organization of tissue-equivalents: the nature and role of contact guidance (1999) Biochem Soc Symp, 65, pp. 27-47
Hagstrom, J. E., Self-assembling complexes for in vivo gene delivery (2000) Curr Opin Mol Ther, 2 (2), pp. 143-149
Schaffer, D. V., Fidelman, N. A., Dan, N., Lauffenberger, D. A., Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery (2000) Biotechnol Bioeng, 67 (5), pp. 598-606
Biomaterials (ISSN: 0142-9612, 1878-5905electronic, 0142-9612linking), 2010 Jan; 31(3): 570-576.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 7.883, 5-year impact factor: 9.076
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-70449134628&partnerID=40&md5=9f08ebdda4ae3c1b8d880885059f6967
Keywords: Cell Migration, Cell Recruitment, Collagen, Dna Complexes Immobilization, Gene Activated Matrices, Non Viral Gene Delivery, Cell Transfection, Collagen Matrices, Control Of Gene Expression, Encoded Proteins, Gene-Activated Matrix, In-Vivo, New Approaches, Polyethylenimines, Time-Lapse Video Microscopy, Tissue Regeneration, Tissue Repair, Transfected Cells, Cytology, Employment, Fluorescence Microscopy, Gene Transfer, Nucleic Acids, Three Dimensional, Cell Immobilization, Avidin, Polyethyleneimine, Animal Cell, Article, Biotinylation, Cell Strain 3t3, Complex Formation, Conjugation, Controlled Study, Embryo, Fluorescence Activated Cell Sorting, Gene Activation, Gene Expression Regulation, Gene Targeting, Genetic Transfection, Internalization, Microenvironment, Mouse, Nonhuman, Priority Journal, Protein Modification, Cell Movement, Extracellular Matrix, Materials Testing, Molecular Structure, Nih 3t3 Cells, Spectrometry, Electrospray Ionization,
Affiliations:
*** IBB - CNR ***
Department of Materials and Production Engineering, University of Naples Federico II, Piazzale Tecchio 80, Naples, 80125, Italy
Interdisciplinary Research Centre on Biomaterials (CRIB), Italian Institute of Technology, IIT, Piazzale Tecchio 80, Naples, 80125, Italy
Department of Biological Science, section Biostructures, University of Naples Federico II, via Mezzocannone 16, Naples, 80134, Italy
References:
Cukierman, E., Pankov, R., Yamada, K.M., Cell interactions with three-dimensional matrices (2002) Curr Opin Cell Biol, 14, pp. 633-63
Kleinman, H.K., Ohilp, D., Hoffman, M.P., Role of the extracellular matrix in morphogenesis (2003) Curr Opin Biotechnol, 14, pp. 526-532
Schmeichel, K.L., Bissell, M.J., Modeling tissue-specific signalling and organ function in three dimensions (2003) J Cell Sci, 116, pp. 2377-2388
Peppas, N.A., Langer, R., New challenge in biomaterials (1994) Science, 263, pp. 1715-1720
Hubbell, J.A., Biomaterials in tissue engineering (1995) Biotechnology, 13 (6), pp. 565-576
Langer, R., Tirrell, D.A., Designing materials for biology and medicine (2004) Nature, 428, pp. 487-492
Lutolf, M.P., Hubbell, J.A., Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering (2005) Nat Biotechnol, 23, pp. 47-55
Hubbell, J.A., Matrix bound growth factors in tissue repair (2006) Swiss Med Wkly, 136, pp. 387-391
Lu, Y., Shansky, J., Del, T.M., Ferland, P., Wang, X., Vandenburgh, H., Recombinant vascular endothelial growth factor secreted from tissue engineered bioartificial muscles promotes localized angiogenesis (2001) Circulation, 104, pp. 594-599
Savarino, L., Baldini, N., Greco, M., Capitani, O., Pinna, S., Valentini, S., The performance of poly-epsiloncaprolacton scaffolds in a rabbit femur model with and without autologous stromal cells and BMP4 (2007) Biomaterials, 28, pp. 3101-3109
Shen, H., Tan, J., Saltzman, W.M., Surface-mediated gene transfer from nanocomposites of controlled texture (2004) Nat Mater, 3, pp. 569-574
Panyam, J., Zhou, W., Prabha, S., Sahoo, S.K., Labhasetwar, V., Rapid endo-lysosomal escape of poly(dl-lactide-co-glycolide) nanoparticles: implication for drug and gene delivery (2002) FASEB J, 16, pp. 1217-1226
Pannier, A.K., Shea, L.D., Controlled release systems for DNA delivery (2004) Mol Ther, 10 (1), pp. 19-24
Fang, J., Zhu, Y.Y., Bonadio, J., Rouleau, J., Goldstein, S., McCauley, L.K., Stimulation of new bone formation by direct transfer of osteogenic plasmid genes (1996) Proc Natl Acad Sci U S A, 93, pp. 5753-5759
Bonadio, J., Smiley, E., Patil, P., Goldstein, S., Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration (1999) Nat Med, 5, pp. 753-759
Bonadio, J., Goldstein, S.A., Levy, R.S., Gene therapy for tissue repair and regeneration (1998) Adv Drug Deliv Rev, 33, pp. 53-69
Shea, L.D., Smiley, E., Bonadio, J., Mooney, D.J., DNA delivery from polymer matrices for tissue engineering (1999) Nat Biotechnol, 17 (6), pp. 551-554
Bonadio, J., Tissue engineering via local gene delivery: Update and future prospects for enhancing the technology (2000) Adv Drug Deliv Rev, 44, pp. 185-194
Endo, M., Kuroda, S., Kondo, H., Maruoka, Y., Ohya, K., Kasugai, S., Bone regeneration by modified gene-activated matrix: effectiveness in segmental tibial defects in rats (2006) Tissue Eng, 12 (3), pp. 489-497
Guo, T., Zhao, J., Chang, J., Ding, Z., Hong, H., Chen, J., Porous chitosan-gelatin scaffold containing plasmid DNA encoding transforming growth factor-beta1 for chondrocytes proliferation (2006) Biomaterials, 27 (7), pp. 1095-1103
Chandler, L.A., Gu, D.L., Ma, C., Gonzalez, A.M., Doukas, J., Nguyen, T., Matrix-enabled gene transfer for cutaneous wound repair (2000) Wound Repair Regen, 8 (6), pp. 473-479
Segura, T., Chung, P.H., Shea, L.D., DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach (2005) Biomaterials, 26, pp. 1575-1584
Lau, Y.K., Gobin, A.M., West, J.L., Overexpression of lysyl oxidase to increase matrix crosslinking and improve tissue strength in dermal wound healing (2006) Ann Biomed Eng, 34, pp. 1239-1246
Peng, L., Cheng, X., Zhuo, R., Lan, J., Wang, Y., Shi, B., Novel gene-activated matrix with embedded chitosan/plasmid DNA nanoparticles encoding PDGF for periodontal tissue engineering (2009) J Biomed Mater Res A, 90 (2), pp. 564-576
Cao, L., Mooney, D.J., Spatiotemporal control over growth factor signaling for therapeutic neovascularization (2007) Adv Drug Deliv Rev, 59 (13), pp. 1340-1350
DeLong, S.A., Gobin, A.S., West, J.L., Covalent immobilization of RGDS on hydrogel surfaces to direct cell alignment and migration (2005) J Control Release, 109 (1-3), pp. 139-148
DeLong, S.A., Moon, J.J., West, J.L., Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration (2005) Biomaterials, 26, pp. 3227-3234
Boyden, S., The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes (1962) J Exp Med, 115, pp. 453-466
Nelson, R.D., Quie, P.G., Simmons, R.L., Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leucocytes and monocytes (1975) J Immunol, 115, pp. 1650-1656
Moghe, P.V., Nelson, R.D., Tranquillo, R.T., Cytokine-stimulated chemotaxis of human neutrophils in a 3-D conjoined fibrin gel assay (1995) J Immunol Methods, 180, pp. 193-211
Knapp, D.M., Helou, E.F., Tranquillo, R.T., A fibrin or collagen gel assay for tissue cell chemotaxis: assessment of fibroblast chemotaxis to RGDSP (1999) Exp Cell Res, 247, pp. 543-553
Kipper, M.J., Kleinman, H.K., Wang, F.W., New method for modeling connective-tissue cell migration: improved accuracy on motility parameters (2007) Biophys J, 93 (5), pp. 1797-1808
Maheshwari, G., Lauffenburger, D.A., Deconstructing (and reconstructing) cell migration (1998) Microsc Res Tech, 43, pp. 358-368
Distasi, C., Ariano, P., Zamburlin, P., Ferraro, M., In vitro analysis of neuron-glial cell interactions during cellular migration (2002) Eur Biophys J, 31, pp. 81-88
Smith, J.T., Tomfohr, J.K., Wells, M.C., Beebe, T.P., Kepler, T.B., Reichert, W.M., Measurement of cell migration on surface-bound fibronectin gradients (2004) Langmuir, 20, pp. 8279-8286
Myles, J.L., Burgess, B.T., Dickinson, R.B., Modification of the adhesive properties of collagen by covalent grafting with RGD peptides (2000) J Biomater Sci Polym Ed, 11, pp. 69-86
De Rosa, E., Urciuolo, F., Borselli, C., Gerbasio, D., Imparato, G., Netti, P.A., Time and space evolution of transport properties in agarose-chondrocyte constructs (2006) Tissue Eng, 12, pp. 2193-2201
Stokes, C.L., Lauffenburger, D.A., Williams, S.K., Migration of individual microvessel endothelial cells: stochastic model and parameter measurement (1991) J Cell Sci, 99, pp. 419-430
Jang, J.H., Houchin, T.L., Shea, L.D., Gene delivery from polymeric scaffolds for tissue engineering (2004) Expert Rev Med Devices, 1 (1), pp. 127-138
Nishimura, I., Garrell, R., Hedrick, M., Iida, K., Osher, S., Wu, B., Precursor tissue analogs as a tissue-engineering strategy (2003) Tissue Eng, 9 (1), pp. 77-89
Tranquillo, R.T., Self-organization of tissue-equivalents: the nature and role of contact guidance (1999) Biochem Soc Symp, 65, pp. 27-47
Segura, T., Volk, M.J., Shea, L.D., Substrate-mediated DNA delivery: role of the cationic polymer structure and extent of modification (2003) J Control Release, 93 (1), pp. 69-84
Hagstrom, J.E., Self-assembling complexes for in vivo gene delivery (2000) Curr Opin Mol Ther, 2 (2), pp. 143-149
Schaffer, D.V., Fidelman, N.A., Dan, N., Lauffenberger, D.A., Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery (2000) Biotechnol Bioeng, 67 (5), pp. 598-606
Kleinman, H. K., Ohilp, D., Hoffman, M. P., Role of the extracellular matrix in morphogenesis (2003) Curr Opin Biotechnol, 14, pp. 526-532
Schmeichel, K. L., Bissell, M. J., Modeling tissue-specific signalling and organ function in three dimensions (2003) J Cell Sci, 116, pp. 2377-2388
Peppas, N. A., Langer, R., New challenge in biomaterials (1994) Science, 263, pp. 1715-1720
Hubbell, J. A., Biomaterials in tissue engineering (1995) Biotechnology, 13 (6), pp. 565-576
Lutolf, M. P., Hubbell, J. A., Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering (2005) Nat Biotechnol, 23, pp. 47-55
Hubbell, J. A., Matrix bound growth factors in tissue repair (2006) Swiss Med Wkly, 136, pp. 387-391
Pannier, A. K., Shea, L. D., Controlled release systems for DNA delivery (2004) Mol Ther, 10 (1), pp. 19-24
Fang, J., Zhu, Y. Y., Bonadio, J., Rouleau, J., Goldstein, S., McCauley, L. K., Stimulation of new bone formation by direct transfer of osteogenic plasmid genes (1996) Proc Natl Acad Sci U S A, 93, pp. 5753-5759
Shea, L. D., Smiley, E., Bonadio, J., Mooney, D. J., DNA delivery from polymer matrices for tissue engineering (1999) Nat Biotechnol, 17 (6), pp. 551-554
Chandler, L. A., Gu, D. L., Ma, C., Gonzalez, A. M., Doukas, J., Nguyen, T., Matrix-enabled gene transfer for cutaneous wound repair (2000) Wound Repair Regen, 8 (6), pp. 473-479
Lau, Y. K., Gobin, A. M., West, J. L., Overexpression of lysyl oxidase to increase matrix crosslinking and improve tissue strength in dermal wound healing (2006) Ann Biomed Eng, 34, pp. 1239-1246
DeLong, S. A., Gobin, A. S., West, J. L., Covalent immobilization of RGDS on hydrogel surfaces to direct cell alignment and migration (2005) J Control Release, 109 (1-3), pp. 139-148
DeLong, S. A., Moon, J. J., West, J. L., Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration (2005) Biomaterials, 26, pp. 3227-3234
Nelson, R. D., Quie, P. G., Simmons, R. L., Chemotaxis under agarose: a new and simple method for measuring chemotaxis and spontaneous migration of human polymorphonuclear leucocytes and monocytes (1975) J Immunol, 115, pp. 1650-1656
Moghe, P. V., Nelson, R. D., Tranquillo, R. T., Cytokine-stimulated chemotaxis of human neutrophils in a 3-D conjoined fibrin gel assay (1995) J Immunol Methods, 180, pp. 193-211
Knapp, D. M., Helou, E. F., Tranquillo, R. T., A fibrin or collagen gel assay for tissue cell chemotaxis: assessment of fibroblast chemotaxis to RGDSP (1999) Exp Cell Res, 247, pp. 543-553
Kipper, M. J., Kleinman, H. K., Wang, F. W., New method for modeling connective-tissue cell migration: improved accuracy on motility parameters (2007) Biophys J, 93 (5), pp. 1797-1808
Smith, J. T., Tomfohr, J. K., Wells, M. C., Beebe, T. P., Kepler, T. B., Reichert, W. M., Measurement of cell migration on surface-bound fibronectin gradients (2004) Langmuir, 20, pp. 8279-8286
Myles, J. L., Burgess, B. T., Dickinson, R. B., Modification of the adhesive properties of collagen by covalent grafting with RGD peptides (2000) J Biomater Sci Polym Ed, 11, pp. 69-86
Stokes, C. L., Lauffenburger, D. A., Williams, S. K., Migration of individual microvessel endothelial cells: stochastic model and parameter measurement (1991) J Cell Sci, 99, pp. 419-430
Jang, J. H., Houchin, T. L., Shea, L. D., Gene delivery from polymeric scaffolds for tissue engineering (2004) Expert Rev Med Devices, 1 (1), pp. 127-138
Tranquillo, R. T., Self-organization of tissue-equivalents: the nature and role of contact guidance (1999) Biochem Soc Symp, 65, pp. 27-47
Hagstrom, J. E., Self-assembling complexes for in vivo gene delivery (2000) Curr Opin Mol Ther, 2 (2), pp. 143-149
Schaffer, D. V., Fidelman, N. A., Dan, N., Lauffenberger, D. A., Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery (2000) Biotechnol Bioeng, 67 (5), pp. 598-606
Cell recruitment and transfection in gene activated collagen matrix
Realization of systems able to both recruit cells and influence their fate (affecting their processes) represents a new approach for tissue regeneration. We investigated the potency of gene activated matrix (CAM) and implemented the CAM strategy in order to achieve a control of gene expression, as well as a specific cell recruitment. To this aim we developed a 3D DNA bio-activated collagen matrix by Poly (ethylenimine) (PEI)/DNA complex immobilization in the matrix through biotin/avidin bond. Moreover, we realised a serum based chemotactic gradient within the matrix in order to directionally attract NIH3T3 cells. In this system, cells are recruited and forced to migrate through the matrix where they find the bound PEI/DNA complexes and are transfected. The transfected cells can act as local in vivo bioreactors, secreting plasmid encoded proteins that augment tissue repair and regeneration. 3D cell migration and cell transfection were monitored through time-lapse video microscopy and fluorescence microscopy. Cell transfection was also quantified through FACS analysis. Results show that our engineered matrix is able to recruit external cells and transfect them once internalized, therefore it could help in tissue repairing strategy. (C) 2009 Elsevier Ltd. All rights reserved.
Realization of systems able to both recruit cells and influence their fate (affecting their processes) represents a new approach for tissue regeneration. We investigated the potency of gene activated matrix (CAM) and implemented the CAM strategy in order to achieve a control of gene expression, as well as a specific cell recruitment. To this aim we developed a 3D DNA bio-activated collagen matrix by Poly (ethylenimine) (PEI)/DNA complex immobilization in the matrix through biotin/avidin bond. Moreover, we realised a serum based chemotactic gradient within the matrix in order to directionally attract NIH3T3 cells. In this system, cells are recruited and forced to migrate through the matrix where they find the bound PEI/DNA complexes and are transfected. The transfected cells can act as local in vivo bioreactors, secreting plasmid encoded proteins that augment tissue repair and regeneration. 3D cell migration and cell transfection were monitored through time-lapse video microscopy and fluorescence microscopy. Cell transfection was also quantified through FACS analysis. Results show that our engineered matrix is able to recruit external cells and transfect them once internalized, therefore it could help in tissue repairing strategy. (C) 2009 Elsevier Ltd. All rights reserved.
Cell recruitment and transfection in gene activated collagen matrix
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Cell recruitment and transfection in gene activated collagen matrix
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Zannetti A, Benga G, Brunetti A, Napolitano F, Avallone L, Pelagalli A
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Pisano M, De Paola I, Nieddu V, Sassu I, Cossu S, Galleri G, Del Gatto A, Budroni M, Cossu A, Saviano M, Palmieri G, Zaccaro L, Rozzo C
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* Role of Aquaporins in the Physiological Functions of Mesenchymal Stem Cells (54 views) (PDF 15 views)
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Impact Factor: 4.366
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Hill BS, Sarnella A, Capasso D, Comegna D, Del Gatto A, Gramanzini M, Albanese S, Saviano M, Zaccaro L, Zannetti A
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Impact Factor: 6.126
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Supuran CT, Alterio V, Di Fiore A, D'Ambrosio K, Carta F, Monti SM, De Simone G
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Impact Factor: 8.29
View Export to BibTeX Export to EndNote
Ugga L, Romeo V, Tedeschi E, Brunetti A, Quarantelli M
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J Neurosci Methods (ISSN: 0165-0270linking, 1872-678xelectronic), 2018 Jun 18; 310: 12-23.
Impact Factor: 2.668
View Export to BibTeX Export to EndNote
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L
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Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646.
Impact Factor: 5.008
View Export to BibTeX Export to EndNote
Ferrucci V, De Antonellis P, Pennino FP, Asadzadeh F, Virgilio A, Montanaro D, Galeone A, Boffa I, Pisano I, Scognamiglio I, Navas L, Diana D, Pedone E, Gargiulo S, Gramanzini M, Brunetti A, Danielson L, Carotenuto M, Liguori L, Verrico A, Quaglietta L, Errico ME, Del Monaco V, D'Argenio V, Tirone F, Mastronuzzi A, Donofrio V, Giangaspero F, Picard D, Remke M, Garzia L, Daniels C, Delattre O, Swartling FJ, Weiss WA, Salvatore F, Fattorusso R, Chesler L, Taylor MD, Cinalli G, Zollo M
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Brain (ISSN: 1460-2156electronic, 0006-8950linking), 2018 May 1; 141(5): 1300-1319.
Impact Factor: 9.915
View Export to BibTeX Export to EndNote
Meli R, Pirozzi C, Pelagalli A
* New Perspectives on the Potential Role of Aquaporins (AQPs) in the Physiology of Inflammation (260 views)
Front Physiol (ISSN: 1664-042xprint, 1664-042xlinking), 2018 Feb 16; 9(FEB): 101-101.
Impact Factor: 4.134
View Export to BibTeX Export to EndNote
Pelagalli A, Nardelli A, Lucarelli E, Zannetti A, Brunetti A
* Autocrine signals increase Ovine Mesenchymal Stem Cells migration through Aquaporin-1 and CXCR4 overexpression (659 views)
J Cell Physiol (ISSN: 1097-4652electronic, 0021-9541linking), 2018 Jan 18; 233(8): 6241-6249.
Impact Factor: 5.546
View Export to BibTeX Export to EndNote
Camorani S, Hill BS, Fontanella R, Greco A, Gramanzini M, Auletta L, Gargiulo S, Albanese S, Lucarelli E, Cerchia L, Zannetti A
* Inhibition of Bone Marrow-Derived Mesenchymal Stem Cells Homing Towards Triple-Negative Breast Cancer Microenvironment Using an Anti-PDGFRbeta Aptamer (691 views) (PDF 210 views)
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Impact Factor: 8.537
View Export to BibTeX Export to EndNote
Roviello GN, Iannitti R, Roviello V, Palumbo R, Simonyan H, Vicidomini C
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Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2017 Feb; 49(2): 327-335.
Impact Factor: 2.906
View Export to BibTeX Export to EndNote
Fontanella R, Pelagalli A, Nardelli A, D'Alterio C, Ierano C, Cerchia L, Lucarelli E, Scala S, Zannetti A
* A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion (931 views) (PDF 283 views)
Cancer Lett (ISSN: 0304-3835), 2015 Oct 27; 370(1): 100-107.
Impact Factor: 7.36
View Export to BibTeX Export to EndNote
Giacomelli C, Trincavelli ML, Satriano C, Hansson O, La Mendola D, Rizzarelli E, Martini C
* Copper (II) ions modulate Angiogenin activity in human endothelial cells (422 views)
Int J Biochem Cell B (ISSN: 1357-2725), 2015 Mar; 60: 185-196.
Impact Factor: 3.905
View Export to BibTeX Export to EndNote
Vincenzi M, Costantini S, Scala S, Tesauro D, Accardo A, Leone M, Colonna G, Guillon J, Portella L, Trotta AM, Ronga L, Rossi F
* Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4 (528 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2015; 16(6): 12159-12173.
Impact Factor: 3.257
View Export to BibTeX Export to EndNote
Perri F, Pacelli R, Della Vittoria Scarpati G, Cella L, Giuliano M, Caponigro F, Pepe S
* Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications (522 views)
Head Neck-J Sci Spec (ISSN: 1043-3074), 2015; 37(5): 763-770.
Impact Factor: 2.76
View Export to BibTeX Export to EndNote
Neve Polimeno M, Ierano C, D'Alterio C, Simona Losito N, Napolitano M, Portella L, Scognamiglio G, Tatangelo F, Maria Trotta A, Curley S, Costantini S, Liuzzi R, Izzo F, Scala S
* CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not (603 views)
Cell Mol Immunol (ISSN: 1672-7681), 2014 Nov 3; 12(4): 474-482.
Impact Factor: 4.112
View Export to BibTeX Export to EndNote
Formisano L, Nappi L, Rosa R, Marciano R, D'Amato C, D'Amato V, Damiano V, Raimondo L, Iommelli F, Scorziello A, Troncone G, Veneziani BM, Parsons SJ, De Placido S, Bianco R
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Breast Cancer Res Biomed Central Ltd (ISSN: 1465-5411), 2014; 16(3): R45-R45.
Impact Factor: 0.635
View Export to BibTeX Export to EndNote
Portella L, Vitale R, De Luca S, D'Alterio C, Ieranò C, Napolitano M, Riccio A, Polimeno MN, Monfregola L, Barbieri A, Luciano A, Ciarmiello A, Arra C, Castello G, Amodeo P, Scala S
* Preclinical Development of a Novel Class of CXCR4 Antagonist Impairing Solid Tumors Growth and Metastases (503 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Sep 13; 8(9): N/D-N/D.
Impact Factor: 3.534
View Export to BibTeX Export to EndNote
Romano S, Staibano S, Greco A, Brunetti A, Nappo G, Ilardi G, Martinelli R, Sorrentino A, Di Pace A, Mascolo M, Bisogni R, Scalvenzi M, Alfano B, Romano M
* FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential (430 views) (PDF 242 views)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2013 Apr 4; 4(6): e578-e578.
Impact Factor: 5.333
View Export to BibTeX Export to EndNote
Pisano M, De Paola I, Nieddu V, Sassu I, Cossu S, Galleri G, Del Gatto A, Budroni M, Cossu A, Saviano M, Palmieri G, Zaccaro L, Rozzo C
* In vitro activity of the alphavbeta3 integrin antagonist RGDechi-hCit on malignant melanoma cells (447 views)
Anticancer Res (ISSN: 0250-7005, 0250-0700, 1791-7530electronic), 2013 Mar; 33(3): 871-879.
Impact Factor: 1.045
View Export to BibTeX Export to EndNote
Galasso G, De Rosa R, Ciccarelli M, Sorriento D, Del Giudice C, Strisciuglio T, De Biase C, Luciano R, Piccolo R, Pierri A, Di Gioia G, Prevete N, Trimarco B, Piscione F, Iaccarino G
* β2-adrenergic receptor stimulation improves endothelial progenitor cell-mediated ischemic neoangiogenesis (471 views)
Circ Res (ISSN: 0009-7330, 1524-4571electronic, 0009-7330linking), 2013; 112(7): 1026-1034.
Impact Factor: 11.089
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Finetti F, Basile A, Capasso D, Di Gaetano S, Di Stasi R, Pascale M, Turco CM, Ziche M, Morbidelli L, D'Andrea LD
* Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis (603 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2012 Sep 1; 84(3): 303-311.
Impact Factor: 4.576
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Guarnieri D, De Capua A, Ventre M, Borzacchiello A, Pedone C, Marasco D, Ruvo M, Netti PA
* Covalently immobilized RGD gradient on PEG hydrogel scaffold influences cell migration parameters (572 views)
Acta Biomaterialia (ISSN: 1878-7568, 1742-7061), 2010 Jul; 6(7): 2532-2539.
Impact Factor: 4.824
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Carriero MV, Longanesi-cattani I, Bifulco K, Maglio O, Lista L, Barbieri A, Votta G, Masucci MT, Arra C, Franco R, De Rosa M, Stoppelli MP, Pavone V
* Structure-based design of an urokinase-type plasminogen activator receptor-derived peptide inhibiting cell migration and lung metastasis (490 views)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic, 1535-7163linking), 2009 Sep; 8(9): 2708-2717.
Impact Factor: 4.953
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D'Andrea LD, Del Gatto A, De Rosa L, Romanelli A, Pedone C
* Peptides targeting angiogenesis related growth factor receptors (14494 views)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1873-4286, 1381-6128), 2009 Jul; 15(21): 2414-2429.
Impact Factor: 4.414
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Ierano C, Giuliano P, D'Alterio C, Cioffi M, Mettivier V, Portella L, Napolitano M, Barbieri A, Arra C, Liguori G, Franco R, Palmieri G, Rozzo C, Pacelli R, Castello G, Scala S
* A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration (394 views)
Cell Cycle (ISSN: 1538-4101), 2009 Apr 15; 8(8): 1228-1237.
Impact Factor: 4.087
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Pavone V, Lista L, Maglio O, Longanesi-cattani I, Bifulco K, Arra C, V , Carriero M
* Sub-femtomolar activity of a new cell migration inhibitor (214 views)
Biopolymers, 2009; 92: 350-350.
Impact Factor: 0
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Gioia M, Monaco S, Van Den Steen PE, Sbardella D, Grasso G, Marini S, Overall CM, Opdenakker G, Coletta M
* The Collagen Binding Domain of Gelatinase A Modulates Degradation of Collagen IV by Gelatinase (458 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009; 386(2): 419-434.
Impact Factor: 3.871
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Bifulco K, Longanesi-cattani I, Gargiulo L, Maglio O, Cataldi M, De Rosa M, Stoppelli MP, Pavone V, Carriero MV
* An urokinase receptor antagonist that inhibits cell migration by blocking the formyl peptide receptor (380 views)
Febs Lett (ISSN: 0014-5793print, 0014-5793linking, 1873-3468electronic), 2008 Apr 2; 582(7): 1141-1146.
Impact Factor: 3.264
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Guarnieri D, Borzacchiello A, De Capua A, Marasco D, Ruvo M, Netti PA
* Dependence of cell migration parameters on steepness of RGD gradient slope (377 views)
World Biomater Congr (ISSN: 9781-6156), 2008; 1: 271-271.
Impact Factor: 0
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Sorriento D, Ciccarelli M, Santulli G, Campanile A, Altobelli GG, Cimini V, Galasso G, Astone D, Piscione F, Pastore L, Trimarco B, Iaccarino G
* The G-protein-coupled receptor kinase 5 inhibits NFκB transcriptional activity by inducing nuclear accumulation of IκBα (438 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2008; 105(46): 17818-17823.
Impact Factor: 9.38
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Bucci EM, Valente M, Musumeci D, Sapio R, Anrò V, Roviello GN, Moccia M
* ODN-based drugs for targeting of extracellular proteins (284 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1047-1050.
Impact Factor: 0.723
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D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
* Peptide-based molecules in angiogenesis (828 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285, 1747-0277linking), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
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Zannetti A, Del Vecchio S, Romanelli A, Scala S, Saviano M, Cali' G, Stoppelli MP, Pedone C, Salvatore M
* Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells (511 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2005 Nov 1; 70(9): 1277-1287.
Impact Factor: 3.617
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Carriero M, Del Vecchio S, Capozzoli M, Franco P, Fontana L, Zannetti A, Botti G, D'Aiuto G, Salvatore M, Stoppelli M
Urokinase receptor interacts with alpha(v)beta(5) vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer (393 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1999 Oct 15; 59(20): N/D-N/D.
Impact Factor: 8.614
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34 Records (28 excluding Abstracts).
Total impact factor: 155.356 (137.24 excluding Abstracts).
Total 5 year impact factor: 133.48 (115.521 excluding Abstracts).
Total impact factor: 155.356 (137.24 excluding Abstracts).
Total 5 year impact factor: 133.48 (115.521 excluding Abstracts).
381 views. Last view on Monday 06 March 2023, 22:59:51
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