Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction(721 views) Spadafora M, Varrella P, Acampa W, Spirito M, Nappi C, Mansi L, Miletto P, Rosato G, Cuocolo A
Keywords: Myocardial Perfusion, Myocardial Viability, Ventricular Function, Isosorbide Dinitrate, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Adult, Aged, Article, Clinical Article, Female, Heart Left Ventricle Ejection Fraction, Heart Left Ventricle Enddiastolic Volume, Heart Left Ventricle Function, Heart Muscle Revascularization, Human, Ischemic Heart Disease, Sensitivity And Specificity, Single Photon Emission Computer Tomography, Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography, Middle Aged, Myocardial Ischemia, Predictive Value Of Tests, Recovery Of Function, Reperfusion, Stroke Volume, Tissue Survival, Ventricular Dysfunction,
Affiliations: *** IBB - CNR ***
Department of Imaging, A.O.R.N. S.G. Moscati, Avellino, Italy
Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
Institute of Diagnostic and Nuclear Development, SDN Foundation, Naples, Italy
Department of Cardiology and Heart Surgery, A.O.R.N. S.G. Moscati, Avellino, Italy
References: Not available.
Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction
Purpose: The aim of the study was to evaluate a novel polar map of myocardial viability obtained by gated SPECT imaging to predict functional recovery after revascularization in patients with ischaemic left ventricular (LV) dysfunction. Methods: The study group comprised 17 patients (15 men, mean age 58∈±∈9 years) with ischaemic LV dysfunction (ejection fraction ≥40%) who underwent nitrate-enhanced gated SPECT before and 6 months after coronary revascularization. A parametric image of viable myocardium (VIA) was obtained using a semiautomated method to subtract the point-to-point motion polar map from the perfusion polar map. A parametric image of segments with functional recovery (REC) was obtained by subtracting the baseline motion polar map from the motion polar map after revascularization. Results: Of the total 340 segments, 248 (73%) were considered viable on the basis of the VIA map. After revascularization, of 248 dysfunctional viable segments 186 (75%) showed an improvement in LV function. An increase in LV ejection fraction (from 30∈±∈10% to 42∈±∈11%, p∈
Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R * 3. 0 T perfusion MR imaging(1347 views) Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812. Impact Factor:0.023 ViewExport to BibTeXExport to EndNote