Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction(414 views) Spadafora M, Varrella P, Acampa W, Spirito M, Nappi C, Mansi L, Miletto P, Rosato G, Cuocolo A
Keywords: Myocardial Perfusion, Myocardial Viability, Ventricular Function, Isosorbide Dinitrate, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Adult, Aged, Article, Clinical Article, Female, Heart Left Ventricle Ejection Fraction, Heart Left Ventricle Enddiastolic Volume, Heart Left Ventricle Function, Heart Muscle Revascularization, Human, Ischemic Heart Disease, Sensitivity And Specificity, Single Photon Emission Computer Tomography, Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography, Middle Aged, Myocardial Ischemia, Predictive Value Of Tests, Recovery Of Function, Reperfusion, Stroke Volume, Tissue Survival, Ventricular Dysfunction,
Affiliations: *** IBB - CNR ***
Department of Imaging, A.O.R.N. S.G. Moscati, Avellino, Italy
Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
Institute of Diagnostic and Nuclear Development, SDN Foundation, Naples, Italy
Department of Cardiology and Heart Surgery, A.O.R.N. S.G. Moscati, Avellino, Italy
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Maurea, S., Cuocolo, A., Soricelli, A., Castelli, L., Nappi, A., Squame, F., Enhanced detection of viable myocardium by technetium-99m-MIBI imaging after nitrate administration in chronic coronary artery disease (1995) J Nucl Med, 36, pp. 1945-1952. , 1:STN:280:DyaK28%2FkvFSrug%3D%3D 7472580
Sciagrà, R., Bisi, G., Santoro, G.M., Agnolucci, M., Zoccarato, O., Fazzini, P.F., Influence of the assessment of defect severity and intravenous nitrate administration during tracer injection on the detection of viable hibernating myocardium with data-based quantitative technetium 99m-labelled sestamibi single photon emission computed tomography (1996) J Nucl Cardiol, 3, pp. 221-230. , 10.1016/S1071-3581(96)90036-7 8805742
Remme, W. J., Swedberg, K., Guidelines for the diagnosis and treatment of chronic heart failure (2001) Eur Heart J, 22, pp. 1527-1560. , Task Force for the Diagnosis and Treatment of Chronic Heart Failure, European Society of Cardiology. 10. 1053/euhj. 2001. 2783 1: STN: 280: DC%2BD3Mvks1CitA%3D%3D 1149298
Cowie, M. R., Wood, D. A., Coats, A. J., Thompson, S. G., Poole-Wilson, P. A., Suresh, V., Incidence and aetiology of heart failure: A population-based study (1999) Eur Heart J, 20, pp. 421-428. , 10. 1053/euhj. 1998. 1280 1: STN: 280: DyaK1M3ivVemuw%3D%3D 10213345
Bax, J. J., Poldermans, D., Elhendy, A., Boersma, E., Rahimtoola, S. H., Sensitivity, specificity and predictive accuracies of various non-invasive techniques for detecting hibernating myocardium (2001) Curr Probl Cardiol, 26, pp. 147-186. , 10. 1067/mcd. 2001. 109973 1: STN: 280: DC%2BD3M7os1SisQ%3D%3D 11276916
Underwood, S. R., Bax, J. J., Vom Dahl, J., Henein, M. J., Van Rossum, A. C., Schwarz, E. R., Imaging techniques for the assessment of myocardial hibernation. Report of a study group of the European Society of Cardiology (2004) Eur Heart J, 25, pp. 815-836. , 10. 1016/j. ehj. 2004. 03. 012 15140530
Patel, R. A., Beller, G. A., Prognostic role of single-photon emission computed tomography (SPECT) imaging in myocardial viability (2006) Curr Opin Cardiol, 21, pp. 457-463. , 10. 1097/01. hco. 0000240582. 83967. d8 16900008
Hesse, B., T gil, K., Cuocolo, A., Anagnostopoulos, C., Bardi s, M., Bax, J., EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology (2005) Eur J Nucl Med Mol Imaging, 32, pp. 855-897. , 10. 1007/s00259-005-1779-y 1: STN: 280: DC%2BD2Mzpt1Kjsg%3D%3D 15909197
Fleiss, J. L., (1981) Statistical Methods for Rates and Proportions, pp. 217-225. , 2 Wiley New York
Bax, J. J., Ansalone, G., Breithardt, O. A., Derumeaux, G., Leclercq, C., Schalij, M. J., Echocardiographic evaluation of cardiac resynchronization therapy: Ready for routine clinical use? A critical appraisal (2004) J Am Coll Cardiol, 44, pp. 1-9. , 10. 1016/j. jacc. 2004. 02. 055 15234396
Patterson, R. E., Pilcher, W. C., Assessing myocardial viability to help select patients for revascularization to improve left ventricular dysfunction due to coronary artery disease (1995) Semin Thorac Cardiovasc Surg, 7, pp. 214-226. , 1: STN: 280: DyaK287hvVSiug%3D%3D 8590746
Allman, K. C., Shaw, L. J., Hachamovitch, R., Udelson, J. E., Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: A meta-analysis (2002) J Am Coll Cardiol, 39, pp. 1151-1158. , 10. 1016/S0735-1097 (02) 01726-6 11923039
Bax, J. J., Van Der Wall, E. E., Haebison, M., Radionuclide techniques for the assessment of myocardial viability and hibernation (2004) Heart, 90 (SUPPL. V), pp. 26-33. , 10. 1136/hrt. 2002. 007575
He, Z. X., Darcourt, J., Guignier, A., Ferrari, E., Bussi re, F., Baudouy, M., Nitrates improve detection of ischaemic but viable myocardium by thallium-201 reinjection SPECT (1993) J Nucl Med, 34, pp. 1472-1477. , 1: STN: 280: DyaK3szlvF2mtA%3D%3D 8355066
Bisi, G., Sciagr, R., Santoro, G. M., Rossi, V., Fazzini, P. F., Technetium-99m-sestamibi imaging with nitrate infusion to detect viable hibernating myocardium and predict postrevascularisation recovery (1995) J Nucl Med, 36, pp. 1994-2000. , 1: STN: 280: DyaK28%2FkvFSqtw%3D%3D 7472587
Sciagr, R., Bisi, G., Santoro, G. M., Agnolucci, M., Zoccarato, O., Fazzini, P. F., Influence of the assessment of defect severity and intravenous nitrate administration during tracer injection on the detection of viable hibernating myocardium with data-based quantitative technetium 99m-labelled sestamibi single photon emission computed tomography (1996) J Nucl Cardiol, 3, pp. 221-230. , 10. 1016/S1071-3581 (96) 90036-7 8805742
Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction
Purpose: The aim of the study was to evaluate a novel polar map of myocardial viability obtained by gated SPECT imaging to predict functional recovery after revascularization in patients with ischaemic left ventricular (LV) dysfunction. Methods: The study group comprised 17 patients (15 men, mean age 58∈±∈9 years) with ischaemic LV dysfunction (ejection fraction ≥40%) who underwent nitrate-enhanced gated SPECT before and 6 months after coronary revascularization. A parametric image of viable myocardium (VIA) was obtained using a semiautomated method to subtract the point-to-point motion polar map from the perfusion polar map. A parametric image of segments with functional recovery (REC) was obtained by subtracting the baseline motion polar map from the motion polar map after revascularization. Results: Of the total 340 segments, 248 (73%) were considered viable on the basis of the VIA map. After revascularization, of 248 dysfunctional viable segments 186 (75%) showed an improvement in LV function. An increase in LV ejection fraction (from 30∈±∈10% to 42∈±∈11%, p∈
Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R * 3. 0 T perfusion MR imaging(726 views) Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812. Impact Factor:0.023 ViewExport to BibTeXExport to EndNote