Intestinal amyloidosis: two cases with different patterns of clinical and imaging presentation(477 views) Mainenti PP, Segreto S, Mancini M, Rispo A, Cozzolino I, Masone S, Rinaldi CR, Nardone G, Salvatore M
World J Gastroentero (ISSN: 2219-2840, 1007-9327, 1007-9327linking), 2010 May 28; 16(20): 2566-2570.
IBB CNR, Naples, Via Pansini 5, 80131, Naples, Italy. pierpamainenti@hotmail.com
Department of Biomorphological and Functional Sciences, Section of Radiology, University of Naples 'Federico II', Via Pansini 5, 80131, Naples, Italy
Department of Gastroenterology, University of Naples 'Federico II', Via Pansini 5, 80131, Naples, Italy
Department of General Surgery, Geriatry and Endoscopy, University of Naples 'Federico II', Via Pansini 5, 80131, Naples, Italy
Department of Biotechnology, Haematology Unit, University of Naples 'Federico II', Via Pansini 5, 80131, Naples, Italy
References: Not available.
Intestinal amyloidosis: two cases with different patterns of clinical and imaging presentation
The involvement of the small bowel in systemic forms of amyloidosis may be diffuse or very rarely focal. Some cases of focal amyloidomas of the duodenum and jejunum without extraintestinal manifestations have been reported. The focal amyloidomas consisted of extensive amyloid infiltration of the entire intestinal wall thickness. Radiological barium studies, ultrasound and computed tomography (CT) patterns of diffuse small bowel amyloidosis have been described: the signs are non-specific and may include small-bowel dilatation, symmetric bowel wall thickening, mesenteric infiltration, and mesenteric adenopathy. No data are available about the positron emission tomography (PET)/CT and magnetic resonance imaging (MRI) patterns of intestinal amyloidosis. We report two cases of small bowel amyloidosis: the former characterized by focal deposition of amyloid proteins exclusively within blood vessel walls of the terminal ileum, the latter characterized by diffuse intestinal involvement observed on MRI and PET/CT studies.
Intestinal amyloidosis: two cases with different patterns of clinical and imaging presentation
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