Keywords: Nucleic Acid, Nucleobase, Nucleopeptide, Blasticidin S, Chryscandin, Cystocin, Nikkomycin Z, Nucleic Acid Base, Peptide Derivative, Pseudopeptide, Puromycin, Unclassified Drug, Willardiine, Peptide Analysis, Peptide Synthesis, Priority Journal, Protein Dna Binding, Protein Rna Binding, Short Survey, Humans, Nucleosides, Chemistry, Diagnostic Use, Therapeutic Use, Dna Chemistry
, Peptides Chemistry Therapeutic Use
, Rna Chemistry,
Affiliations: *** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, Via Mezzocannone 16, 80134 Naples, Italy
Department of Scienze Biologiche Sez. Biostrutture, Università Degli Studi di Napoli Federico II, via Mezzocannone 16, 80134 Naples, Italy
References: Altenbrunn, F., Seitz, O., O-Allyl protection in the Fmoc-based synthesis of difficult PNA (2008) Org Biomol Chem, 6, pp. 2493-2498. , 1:CAS:528:DC%2BD1cXotVyrsr4%3D 1860026
Astriab-Fisher, A., Sergueev, D.S., Fisher, M., Ramsay Shaw, B., Juliano, R.L., Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates (2000) Biochem Pharmacol, 60, pp. 83-90. , 1:CAS:528:DC%2BD3cXjtVCit78%3D 10807948
Azzam, M.E., Algranati, I.D., Mechanism of puromycin action: Fate of ribosomes after release of nascent protein chains from polysomes (1973) Proc Nat Acad Sci USA, 70, pp. 3866-3869. , 1:CAS:528:DyaE2cXpt1WksQ%3D%3D 4590173
Betts, L., Josey, J.A., Veal, J.M., Jordan, S.R., A nucleic acid triple helix formed by a peptide nucleic acid-DNA complex (1995) Science, 270, pp. 1838-1841. , 1:CAS:528:DyaK2MXhtVSiurbJ 8525381
Boado, R.J., Tsukamoto, H., Pardridge, W.M., Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS (1998) J Pharm Sci, 87, pp. 1308-1315. , 1:CAS:528:DyaK1cXlsVelu74%3D 9811482
Brandt, O., Hoheisel, J.D., Peptide nucleic acids on microarrays and other biosensors (2004) Trends Biotechnol, 22, pp. 617-622. , 1:CAS:528:DC%2BD2cXpslGisb0%3D 15542150
Brasun, J., Oldziej, S., Taddei, M., Kozłowski, H., Impact of Cu(II) and Ni(II) on the structure of chiral peptide nucleic acids having four, six and eight thymines in a peptide side chain (2001) J Inorg Biochem, 85, pp. 79-87. , 1:CAS:528:DC%2BD3MXktlWgu7k%3D 11410227
Buttrey, J.D., Jones, A.S., Walker, R.T., Synthetic Analogues of Polynucleotides-XII(The Resolution of dl-beta-(Thymin-1-yl)Alanine and Polymerisation of the beta-(Thymin-1-yl) Alanines (1975) Tetrahedron, 31, pp. 73-75. , 1:CAS:528:DyaE2MXktFSkt7k%3D
Calabretta, A., Tedeschi, T., Di Cola, G., Corradini, R., Sforza, S., Marchelli, R., Arginine-based PNA microarrays for APOE genotyping (2009) Mol Biosyst, 5, pp. 1323-1330. , 1:CAS:528:DC%2BD1MXht1CqsbnO 19823748
Christensen, L., Fitzpatrick, R., Gildea, B., Petersen, K.H., Hansenn, H.F., Koch, T., Egholm, M., Coull, J., Solid-phase synthesis of peptide nucleic acids (1995) J Pept Sci, 3, pp. 175-183
Corey, D.R., Peptide nucleic acids-expanding the options for nucleic acid recognition (1997) Trends Biotechnol, 15, pp. 224-229. , 1:CAS:528:DyaK2sXjvVajt7c%3D 9183865
Corriveau, M.N., Zhang, N., Holtappels, G., Van Roy, N., Bachert, C., Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization (2009) Am J Rhinol Allergy, 23, pp. 461-465. , 19807976
De La Torre, B.G., Aviñó, A., Tarrason, G., Piulats, J., Albericio, F., Eritja, R., Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids (1994) Tetrahedron Lett, 35, pp. 2733-2736
Demers, D.B., Curry, E.T., Egholm, M., Sozer, A.C., Enhanced PCR amplification of VNTR locus D1S80 using peptide nucleic acid (PNA) (1995) Nucleic Acids Res, 23, pp. 3050-3055. , 1:CAS:528:DyaK2MXnvVekurc%3D 7659530
Demidov, V.V., PD-loop technology: PNA openers at work (2001) Expert Rev Mol Diagn, 1, pp. 343-351. , 1:CAS:528:DC%2BD3MXotV2rs7c%3D 11901840
Demidov, V.V., Potaman, V.N., Frank-Kamenetskii, M.D., Egholm, M., Buchardt, O., Sonnichsen, S.H., Stability of peptide nucleic acids in human serum and cellular extracts (1994) Biochem Pharmacol, 48, pp. 1310-1313. , 1:CAS:528:DyaK2cXmsVKhtro%3D 7945427
Diederichsen, U., Pairing properties of alanyl peptide nucleic acids containing an amino acid backbone with alternating configuration (1996) Angew Chem Int Ed, 35, pp. 445-448. , 1:CAS:528:DyaK28XhsFCjt7k%3D
Diederichsen, U., Schmitt, H.W., Self-pairing PNA with alternating alanyl-/homoalanyl backbone (1996) Tetrahedron Lett, 37, pp. 475-478. , 1:CAS:528:DyaK28XmvFGmtg%3D%3D
Diederichsen, U., Weicherdling, D., Diezemann, N., Side chain homologation of alanyl peptide nucleic acids: Pairing selectivity and stacking (2005) Org Biomol Chem, 3, pp. 1058-1066. , 1:CAS:528:DC%2BD2MXhvFyqu7o%3D 15750649
Doel, M.T., Jones, A.S., Taylor, N., An approach to the synthesis of peptide analogues of oligonucleotides (Nucleopeptides) (1969) Tetrahedron Lett, 27, pp. 2285-2288
Dragulescu-Andrasi, A., Rapireddy, S., He, G., Bhattacharya, B., Hyldig-Nielsen, J.J., Zon, G., Ly, D.H., Cell-permeable peptide nucleic acid designed to bind to the 5'-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects (2006) J Am Chem Soc, 128, pp. 16104-16112. , 1:CAS:528:DC%2BD28XhtlCitL%2FN 17165763
Draminski, M., Pitha, J., Polypeptides containing adenine and uracil residues (1978) Makromol Chem, 179, pp. 2195-2200. , 1:CAS:528:DyaE1cXlvVSnsrc%3D
Dueholm, K., Egholm, M., Behrens, C., Christensen, L., Hansen, H.F., Vulpius, T., Petersen, K.H., Buchardt, O., Synthesis of peptide nucleic acid monomers containing the 4 natural nucleobases-thymine, cytosine, adenine, and guanine-and their oligomerization (1994) J Org Chem, 59, pp. 5767-5773. , 1:CAS:528:DyaK2cXmtVKjs78%3D
Egholm, M., Christensen, L., Dueholm, K.L., Buchardt, O., Coull, J., Nielsen, P.E., Efficient pH-independent sequence-specific DNA-binding by pseudoisocytosine-containing bis-PNA (1995) Nucleic Acids Res, 23, pp. 217-222. , 1:CAS:528:DyaK2MXjvFems7Y%3D 7862524
Geotti-Bianchini, P., Beyrath, J., Chaloin, O., Formaggio, F., Bianco, A., Design and synthesis of intrinsically cell-penetrating nucleopeptides (2008) Org Biomol Chem, 6, pp. 3661-3663. , 1:CAS:528:DC%2BD1cXht1WkurrJ 18843393
Gooday, G.W., (1990) Biochemistry of Cell Walls and Membranes in Fungi, 61. , Kuhn PJ, Trinci AP, Jung MJ, Goosey MW, Copping LG (eds) Springer, Berlin
Hanvey, J.C., Peffer, N.J., Bisi, J.E., Antisense and antigene properties of peptide nucleic acids (1992) Science, 258, pp. 1481-1485. , 1:CAS:528:DyaK3sXit1KltLw%3D 1279811
Hector, R.F., Zimmer, B.L., Pappagianis, D., Evaluation of Nikkomycins X and Z in murine models of coccidioidomycosis, histoplasmosis, and blastomycosis (1990) Antimicrobial Agents and Chemotherapy, 34 (4), pp. 587-593
Huang, P.C., Novel synthesis of alpha-PNA monomers by U-4CR (2008) Amino Acids, 34, pp. 449-453. , 1:CAS:528:DC%2BD1cXkvVOrs7g%3D 17497306
Hudson, R.H.E., Wojciechowski, F., A Fmoc/Boc pseudoisocytosine monomer for peptide nucleic acid synthesis (2008) Can J Chem, 86, pp. 1026-1029. , 1:CAS:528:DC%2BD1cXhtlGhtLfF
Ichikawa, Y., Hirata, K., Ohbayashi, M., Isobe, M., Total synthesis of (+)-blasticidin s (2004) Chemistry, 10, pp. 3241-3251. , 1:CAS:528:DC%2BD2cXlvVKhsro%3D 15224333
Inaki, Y., Tohnai, N., Miyabayashi, K., Wada, T., Miyata, M., Isopoly-l-ornithine derivatives of the thymine and thymidine (1998) Nucleos Nucleot Nucl, 17, pp. 339-350. , 1:CAS:528:DyaK1cXhvFartrg%3D
Itaya, M., Yamaguchi, I., Kobayashi, K., Endo, T., Tanaka, T., The blasticidin S resistance gene (bsr) selectable in a single copy state in the Bacillus subtilis chromosome (1990) J Biochem, 107, pp. 799-801. , 1:CAS:528:DyaK3cXkslajsbc%3D 2118136
Kerman, K., Matsubara, Y., Morita, Y., Takamura, Y., Tamiya, E., Peptide nucleic acid modified magnetic beads for intercalator based electrochemical detection of DNA hybridization (2004) Sci Technol Adv Mater, 5, pp. 351-357. , 1:CAS:528:DC%2BD2cXjs1antL4%3D
Kitamatsu, M., Shigeyasu, M., Sisido, M., Novel peptide nucleic acids that contain pyrrolidine rings of various stereoisomers (2002) Peptides 2002, Proceedings of the European Peptide Symposium 27th, pp. 532-533
Knudsen, H., Nielsen, P.E., Antisense properties of duplex- and triplex-forming PNAs Nucl (1996) Acids Res, 24, pp. 494-500. , 1:CAS:528:DyaK28XhtVygtrg%3D
Korshunova, G.A., Ilicheva, I.A., Sumbatyan, N.V., Hyun, K., Design and synthesis of new types of oligonucleopeptides (1997) Lett Pept Sci, 4, pp. 473-476. , 1:CAS:528:DyaK1cXot1WmsQ%3D%3D
Kristensen, I., Larsen, P.O., Gamma-Glutamylwillardiine and gamma-glutamylphenylalanylwillardiine from seeds of Fagus silvatica (1974) Phytochemistry, 13, pp. 2799-27802. , 1:CAS:528:DyaE2MXkvFersLw%3D
Kuwahara, M., Arimitsu, M., Sisido, M., Novel peptide nucleic acid that shows high sequence specificity and all-or-none-type hybridization with the complementary DNA (1999) J Am Chem Soc, 121, pp. 256-257. , 1:CAS:528:DyaK1cXotVCrsL8%3D
Hei, C.L., Liou, K., Dae, H.K., Kang, S.-Y., Woo, J.-S., Jae, K.S., Cystocin, a novel antibiotic, produced by Streptomyces sp. GCA0001: Biological activities (2003) Archives of Pharmacal Research, 26 (6), pp. 446-448. , http://apr.psk.or.kr/home/journal/article_view.asp?articleuid= {2A0FEB57-883D-4AE9-81B7-29274789CCF1}
Lee, H., Jeon, J.H., Lim, J.C., Choi, H., Yoon, Y., Kim, S.K., Peptide nucleic acid synthesis by novel amide formation (2007) Org Lett, 9, pp. 3291-3293. , 1:CAS:528:DC%2BD2sXotlSqtLw%3D 17661472
Lenzi, A., Reginato, G., Taddei, M., Trifilieff, E., Solid phase synthesis of a self complementary (antiparallel) chiral peptidic nucleic acid strand (1995) Tetrahedron Lett, 36, pp. 1717-1718. , 1:CAS:528:DyaK2MXktl2qs78%3D
Lioy, E., Kessler, H., Synthesis of a new chiral peptide analogue of DNA using ornithine subunits and solid-phase peptide synthesis methodologies (1996) Liebigs Ann, 2, pp. 201-204
Liu, M., Arora, S.K., Structural investigations of mode of action of drugs: Structure and conformation of a novel peptidyl nucleoside antibiotic chryscandin hydrochloride pentahydrate (2008) J Antibiot, 61, pp. 322-325. , 1:CAS:528:DC%2BD1cXnvVSrs7g%3D 18653999
Mandrugin, V.A., Sumbatyan, N.V., Korshunova, G.A., Solid phase synthesis of new heterorganic nucleopeptides based on a delta-ornithine backbone (2002) Peptides 2002, Proceedings of the European Peptide Symposium 27th, pp. 216-217
Matsumura, S., Takahashi, T., Ueno, A., Mihara, H., Complementary nucleobase interaction enhances peptide-peptide recognition and self-replicating catalysis (2003) Chemistry, 9, pp. 4829-4837. , 1:CAS:528:DC%2BD3sXot1yktr4%3D 14566891
McMinn, D.L., Greenberg, M.M., Convergent solution-phase synthesis of a nucleopeptide using a protected oligonucleotide (1999) Bioorg Med Chem Lett, 9, pp. 547-550. , 1:CAS:528:DyaK1MXhvVymu7o%3D 10098660
Meierhenrich, U.J., Muñoz Caro, G.M., Bredehöft, J.H., Jessberger, E.K., Thiemann, W.H.P., Identification of diamino acids in the Murchison meteorite (2004) Proc Natl Acad Sci USA, 101, pp. 9182-9186. , 1:CAS:528:DC%2BD2cXltlGqur0%3D 15194825
Musumeci, D., Roviello, G.N., Valente, M., Sapio, R., Pedone, C., Bucci, E.M., New synthesis of PNA-3'DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (2004) Biopolymers, 76, pp. 535-542. , 1:CAS:528:DC%2BD2MXhsFaktg%3D%3D 15526336
Nielsen, P.E., Peptide nucleic acid (PNA): A model structure for the primordial genetic material? (1993) Orig Life Evol Biosph, 23, pp. 323-327. , 1:CAS:528:DyaK2cXmslejsLY%3D 8115163
Nielsen, P.E., Egholm, M., An introduction to peptide nucleic acid (1999) Curr Issues Mol Biol, 1, pp. 89-104. , 1:CAS:528:DyaK1MXntlCksbk%3D 11475704
Nix, D.E., Swezey, R.R., Hector, R., Galgiani, J.N., Pharmacokinetics of nikkomycin z after single rising oral doses (2009) Antimicrob Agents Chemother, 53, pp. 2517-2521. , 1:CAS:528:DC%2BD1MXntFGksro%3D 19349517
Oguma, T., Ono, T., Kajiwara, T., Sato, M., Miyahira, Y., Arino, H., Yoshihara, Y., Tadakuma, T., CD4(+)CD8(+) thymocytes are induced to cell death by a small dose of puromycin via ER stress (2009) Cell Immunol, 260, pp. 21-27. , 1:CAS:528:DC%2BD1MXhtlCms7nL 19665696
Ortiz, E., Estrada, G., Lizardi, P.M., PNA molecular beacons for rapid detection of PCR amplicons (1998) Mol Cell Probes, 12, pp. 219-226. , 1:CAS:528:DyaK1cXlslOlurg%3D 9727198
Orum, H., Nielsen, P.E., Egholm, M., Berg, R.H., Buchardt, O., Stanley, C., Single base pair mutation analysis by PNA directed PCR clamping (1993) Nucleic Acids Res, 21, pp. 5332-5336. , 1:STN:280:DyaK2c%2FovFersg%3D%3D 8265345
Perry-O'Keefe, H., Yao, X.W., Coull, J.M., Fuchs, M., Egholm, M., Peptide nucleic acid pre-gel hybridization: An alternative to Southern hybridization (1996) Proc Natl Acad Sci USA, 93, pp. 14670-14675. , 8962112
Plant, A., Thompson, P., Williams, D.M., Application of the Ugi reaction for the one-pot synthesis of uracil polyoxin C analogues (2009) J Org Chem, 74, pp. 4870-4873. , 1:CAS:528:DC%2BD1MXmtFKitbk%3D 19456169
Pothukanuri, S., Pianowski, Z., Winssinger, N., Expanding the scope and orthogonality of PNA synthesis (2008) Eur J Org Chem, 18, pp. 3141-3148
Raukas, E., Kooli, K., Raim, T., Lidaks, M., Krisane, V., Paegle, R., Lulle, I., Interaction of oligopeptides containing residues of dl-beta-(uracilyl-1)- , dl-beta-(adeninyl-9)-alpha-alanines and lysines with poly(A) and DNA (1982) Stud Biophys, 89, pp. 187-195. , 1:CAS:528:DyaL38XmtFSku7o%3D
Rebuffat, A.G., Nawrocki, A.R., Nielsen, P.E., Gene delivery by a steroid-peptide nucleic acid conjugate (2002) FASEB J, 16, pp. 1426-1428. , 1:CAS:528:DC%2BD38XntV2rs70%3D 12205036
Roviello, G.N., Moccia, M., Sapio, R., Valente, M., Bucci, E.M., Castiglione, M., Pedone, C., Musumeci, D., Synthesis, characterization and hybridization studies of new nucleo-gamma-peptides based on diaminobutyric acid (2006) J Pept Sci, 12, pp. 829-835. , 1:CAS:528:DC%2BD2sXktFar 17131297
Roviello, G.N., Musumeci, D., Moccia, M., Castiglione, M., Sapio, R., Valente, M., Bucci, E.M., Pedone, C., DabPNA: Design, synthesis, and DNA binding studies (2007) Nucleosides Nucleotides Nucleic Acids, 26, pp. 1307-1310. , 1:CAS:528:DC%2BD2sXhtl2hurnJ 18066773
Roviello Gn, G., Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (2009) Amino Acids, , doi: 10.1007/s00726-009-0324-x
Roviello, G.N., Gaetano, S.D., Capasso, D., Cesarani, A., Bucci, E.M., Pedone, C., Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (2009) Amino Acids, , doi: 10.1007/s00726-009-0361-5
Roviello, G.N., Crescenzo, C., Capasso, D., Di Gaetano, S., Franco, S., Bucci, E.M., Pedone, C., Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/l-arginine-containing nucleopeptides and preliminary RNA interaction studies (2010) Amino Acids, , doi: 10.1007/S00726-010-0532-4
Sandovsky-Losica, H., Shwartzman, R., Lahat, Y., Segal, E., Antifungal activity against Candida albicans of nikkomycin Z in combination with caspofungin, voriconazole or amphotericin B (2008) J Antimicrob Chemoth, 62, pp. 635-637. , 1:CAS:528:DC%2BD1cXhtVShsrrK
Sforza, S., Galaverna, G., Dossena, A., Corradini, R., Marchelli, R., Role of chirality and optical purity in nucleic acid recognition by PNA and PNA analogs (2002) Chirality, 14, pp. 591-598. , 1:CAS:528:DC%2BD38XkvFyju7c%3D 12112334
Shvachkin, Y.P., Mishin, G.P., Korshunova, G.A., Advances and prospects in the chemistry of nucleoaminoacids and nucleopeptides (1982) Russ Chem Rev, 51, pp. 178-188
Simmons, C.G., Pitts, A.E., Mayfield, L.D., Shay, J.W., Corey, D.R., Synthesis and permeability of PNA-peptide conjugates (1997) Bioorg Med Chem Lett, 7, pp. 3001-3007. , 1:CAS:528:DyaK1cXitVWrsg%3D%3D
Socher, E., Bethge, L., Knoll, A., Jungnick, N., Herrmann, A., Seitz, O., Low-noise stemless PNA beacons for sensitive DNA and RNA detection (2008) Angew Chem Int Ed Engl, 47, pp. 9555-9559. , 1:CAS:528:DC%2BD1cXhsV2ktbvJ 18949813
Soukchareun, S., Tregear, G.W., Haralambidis, J., Preparation and characterization of antisense oligonucleotide-peptide hybrids containing viral fusion peptides (1995) Bioconj Chem, 6, pp. 43-53. , 1:CAS:528:DyaK2MXjtF2rtbg%3D
Strasdeit, H., New studies on the Murchison meteorite shed light on the pre-RNA world (2005) Chembiochem, 6, pp. 801-803. , 1:CAS:528:DC%2BD2MXksFajs7k%3D 15791685
Svensen, N., Diaz-Mochon, J.J., Bradley, M., Microwave-assisted orthogonal synthesis of PNA-peptide conjugates (2008) Tetrahedron Lett, 49, pp. 6498-6500. , 1:CAS:528:DC%2BD1cXht1Snu7zM
Takemoto, K., Nucleic acid analogs: Conformation and their functionalities Macromol (1985) Chem Suppl, 12, pp. 293-301. , 1:CAS:528:DyaL28Xks1Sru7o%3D
Thomson, S.A., Josey, J.A., Cadilla, R., Gaul, M.D., Hassman, C.F., Luzzio, M.J., Fmoc mediated synthesis of peptide nucleic acids (1995) Tetrahedron, 51, pp. 6179-6194. , 1:CAS:528:DyaK2MXlvFOhtbw%3D
Toure, B.B., Hall, D.G., Natural product synthesis using multicomponent reaction strategies (2009) Chem Rev, 109, pp. 4439-4486. , 1:CAS:528:DC%2BD1MXmsFamsLg%3D 19480390
Turner, J.J., Jones, S., Fabani, M.M., Ivanova, G., Arzumanov, A.A., Gait, M.J., RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA (2007) Blood Cells Mol Dis, 38, pp. 1-7. , 1:CAS:528:DC%2BD2sXht1Cjtw%3D%3D 17113327
Uhlmann, E., Peyman, A., Breipohl, G., Will, D., PNA: Synthetic polyamide nucleic acids with unusual binding properties (1998) Angew Chem Int Ed, 37, pp. 2796-2823. , 1:CAS:528:DyaK1cXnsVGmsbc%3D
Van Der Laan, A.C., Van Amsterdam, I., Tesser, G.I., Van Boom, J.H., Kuyl-Yeheskiely, E., Synthesis of chirally pure ornithine based PNA analogues (1998) Nucleoside Nucleotide Nucleic Acid, 17, pp. 219-231
Veselkov, A.G., Demidov, V., Nielsen, P.E., Frank-Kamenetskii, M.D., A new class of genome rare cutters (1996) Nucleic Acids Res, 24, pp. 2483-2487. , 1:CAS:528:DyaK28XksVyjsb8%3D 8692685
Villa, R., Folini, M., Lualdi, S., Veronese, S., Daidone, M.G., Zaffaroni, N., Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells (2000) FEBS Letters, 473 (2), pp. 241-248. , DOI 10.1016/S0014-5793(00)01540-4, PII S0014579300015404
Weiss, A., Diederichsen, U., Uniformly nucleobase functionalized -peptide helices: Watson-Crick pairing of non-specific aggregation (2007) Eur J Org Chem, pp. 5531-5539
Wojciechowski, F., Hudson, R.H.E., Nucleobase Modifications in Peptide Nucleic Acids (2007) Curr Top Med Chem, 7, pp. 667-679. , 1:CAS:528:DC%2BD2sXlvVGqur4%3D 17430208
Yamaguchi, H., Tanaka, N., Inhibition of protein synthesis by blasticidin S. II. Studies on the site of action in E. coli polypeptide synthesizing systems (1966) J Biochem, 60, pp. 632-642. , 1:CAS:528:DyaF2sXjs1emtg%3D%3D 4860846
Yamashita, M., Tsurumi, Y., Hosoda, J., Chryscandin, a novel peptidyl nucleoside antibiotic. I. Taxonomy, fermentation, isolation and characterization (1984) Journal of Antibiotics, 37 (11), pp. 1279-1283
Yamazaki, T., Komatsu, K., Umemiya, H., Hashimoto, Y., Shudo, K., Kagechika, H., Dinucleotide-analogous tetrapeptides. Specific triplex formation with complementary polynucleotides (1997) Tetrahedron Lett, 38, pp. 8363-8366. , 1:CAS:528:DyaK2sXnslekurs%3D
Zhou, P., Wang, M., Du, L., Fisher, G.W., Waggoner, A., Ly, D.H., Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA) (2003) J Am Chem Soc, 125, pp. 6878-6879. , 1:CAS:528:DC%2BD3sXjsl2hs7c%3D 12783535
Azzam, M. E., Algranati, I. D., Mechanism of puromycin action: Fate of ribosomes after release of nascent protein chains from polysomes (1973) Proc Nat Acad Sci USA, 70, pp. 3866-3869. , 1: CAS: 528: DyaE2cXpt1WksQ%3D%3D 4590173
Boado, R. J., Tsukamoto, H., Pardridge, W. M., Drug delivery of antisense molecules to the brain for treatment of Alzheimer's disease and cerebral AIDS (1998) J Pharm Sci, 87, pp. 1308-1315. , 1: CAS: 528: DyaK1cXlsVelu74%3D 9811482
Buttrey, J. D., Jones, A. S., Walker, R. T., Synthetic Analogues of Polynucleotides-XII (The Resolution of dl-beta- (Thymin-1-yl) Alanine and Polymerisation of the beta- (Thymin-1-yl) Alanines (1975) Tetrahedron, 31, pp. 73-75. , 1: CAS: 528: DyaE2MXktFSkt7k%3D
Corey, D. R., Peptide nucleic acids-expanding the options for nucleic acid recognition (1997) Trends Biotechnol, 15, pp. 224-229. , 1: CAS: 528: DyaK2sXjvVajt7c%3D 9183865
Corriveau, M. N., Zhang, N., Holtappels, G., Van Roy, N., Bachert, C., Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization (2009) Am J Rhinol Allergy, 23, pp. 461-465. , 19807976
De La Torre, B. G., Avi, A., Tarrason, G., Piulats, J., Albericio, F., Eritja, R., Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids (1994) Tetrahedron Lett, 35, pp. 2733-2736
Demers, D. B., Curry, E. T., Egholm, M., Sozer, A. C., Enhanced PCR amplification of VNTR locus D1S80 using peptide nucleic acid (PNA) (1995) Nucleic Acids Res, 23, pp. 3050-3055. , 1: CAS: 528: DyaK2MXnvVekurc%3D 7659530
Demidov, V. V., PD-loop technology: PNA openers at work (2001) Expert Rev Mol Diagn, 1, pp. 343-351. , 1: CAS: 528: DC%2BD3MXotV2rs7c%3D 11901840
Demidov, V. V., Potaman, V. N., Frank-Kamenetskii, M. D., Egholm, M., Buchardt, O., Sonnichsen, S. H., Stability of peptide nucleic acids in human serum and cellular extracts (1994) Biochem Pharmacol, 48, pp. 1310-1313. , 1: CAS: 528: DyaK2cXmsVKhtro%3D 7945427
Doel, M. T., Jones, A. S., Taylor, N., An approach to the synthesis of peptide analogues of oligonucleotides (Nucleopeptides) (1969) Tetrahedron Lett, 27, pp. 2285-2288
Fiandaca, M. J., Hyldig-Nielsen, J. J., Gildae, B. D., Coull, J. M., Self reporting PNA/DNA primers for PCR analysis (2001) Genome Res, 11, pp. 609-613. , 1: CAS: 528: DC%2BD3MXivFOqtbs%3D 11282976
Gooday, G. W., (1990) Biochemistry of Cell Walls and Membranes in Fungi, 61. , Kuhn PJ, Trinci AP, Jung MJ, Goosey MW, Copping LG (eds) Springer, Berlin
Hanvey, J. C., Peffer, N. J., Bisi, J. E., Antisense and antigene properties of peptide nucleic acids (1992) Science, 258, pp. 1481-1485. , 1: CAS: 528: DyaK3sXit1KltLw%3D 1279811
Hector, R. F., Zimmer, B. L., Pappagianis, D., Evaluation of Nikkomycins X and Z in murine models of coccidioidomycosis, histoplasmosis, and blastomycosis (1990) Antimicrobial Agents and Chemotherapy, 34 (4), pp. 587-593
Huang, P. C., Novel synthesis of alpha-PNA monomers by U-4CR (2008) Amino Acids, 34, pp. 449-453. , 1: CAS: 528: DC%2BD1cXkvVOrs7g%3D 17497306
Hudson, R. H. E., Wojciechowski, F., A Fmoc/Boc pseudoisocytosine monomer for peptide nucleic acid synthesis (2008) Can J Chem, 86, pp. 1026-1029. , 1: CAS: 528: DC%2BD1cXhtlGhtLfF
Katritzky, A. R., Narindoshvili, T., Chiral peptide nucleic acid monomers (PNAM) with modified backbones (2008) Org Biomol Chem, 6, pp. 3171-3176. , 1: CAS: 528: DC%2BD1cXpslWmsbo%3D 18698477
Korshunova, G. A., Ilicheva, I. A., Sumbatyan, N. V., Hyun, K., Design and synthesis of new types of oligonucleopeptides (1997) Lett Pept Sci, 4, pp. 473-476. , 1: CAS: 528: DyaK1cXot1WmsQ%3D%3D
Hei, C. L., Liou, K., Dae, H. K., Kang, S. -Y., Woo, J. -S., Jae, K. S., Cystocin, a novel antibiotic, produced by Streptomyces sp. GCA0001: Biological activities (2003) Archives of Pharmacal Research, 26 (6), pp. 446-448. , http: //apr. psk. or. kr/home/journal/article_view. asp? articleuid= {2A0FEB57-883D-4AE9-81B7-29274789CCF1}
Lee, H., Jeon, J. H., Lim, J. C., Choi, H., Yoon, Y., Kim, S. K., Peptide nucleic acid synthesis by novel amide formation (2007) Org Lett, 9, pp. 3291-3293. , 1: CAS: 528: DC%2BD2sXotlSqtLw%3D 17661472
Liu, M., Arora, S. K., Structural investigations of mode of action of drugs: Structure and conformation of a novel peptidyl nucleoside antibiotic chryscandin hydrochloride pentahydrate (2008) J Antibiot, 61, pp. 322-325. , 1: CAS: 528: DC%2BD1cXnvVSrs7g%3D 18653999
Mandrugin, V. A., Sumbatyan, N. V., Korshunova, G. A., Solid phase synthesis of new heterorganic nucleopeptides based on a delta-ornithine backbone (2002) Peptides 2002, Proceedings of the European Peptide Symposium 27th, pp. 216-217
McMinn, D. L., Greenberg, M. M., Convergent solution-phase synthesis of a nucleopeptide using a protected oligonucleotide (1999) Bioorg Med Chem Lett, 9, pp. 547-550. , 1: CAS: 528: DyaK1MXhvVymu7o%3D 10098660
Meierhenrich, U. J., Mu oz Caro, G. M., Bredeh ft, J. H., Jessberger, E. K., Thiemann, W. H. P., Identification of diamino acids in the Murchison meteorite (2004) Proc Natl Acad Sci USA, 101, pp. 9182-9186. , 1: CAS: 528: DC%2BD2cXltlGqur0%3D 15194825
Nielsen, P. E., Peptide nucleic acid (PNA): A model structure for the primordial genetic material? (1993) Orig Life Evol Biosph, 23, pp. 323-327. , 1: CAS: 528: DyaK2cXmslejsLY%3D 8115163
Nielsen, P. E., Egholm, M., An introduction to peptide nucleic acid (1999) Curr Issues Mol Biol, 1, pp. 89-104. , 1: CAS: 528: DyaK1MXntlCksbk%3D 11475704
Nix, D. E., Swezey, R. R., Hector, R., Galgiani, J. N., Pharmacokinetics of nikkomycin z after single rising oral doses (2009) Antimicrob Agents Chemother, 53, pp. 2517-2521. , 1: CAS: 528: DC%2BD1MXntFGksro%3D 19349517
Nollet, A. J. H., Hutino, C. M., Pandit, U. K., Unconventional nucleotide analogues-I (N9-purinyl alpha-amino acids) (1969) Tetrahedron, 25, pp. 5971-5981. , 1: CAS: 528: DyaE3cXnvFCntQ%3D%3D 5377765
Rebuffat, A. G., Nawrocki, A. R., Nielsen, P. E., Gene delivery by a steroid-peptide nucleic acid conjugate (2002) FASEB J, 16, pp. 1426-1428. , 1: CAS: 528: DC%2BD38XntV2rs70%3D 12205036
Roviello, G. N., Moccia, M., Sapio, R., Valente, M., Bucci, E. M., Castiglione, M., Pedone, C., Musumeci, D., Synthesis, characterization and hybridization studies of new nucleo-gamma-peptides based on diaminobutyric acid (2006) J Pept Sci, 12, pp. 829-835. , 1: CAS: 528: DC%2BD2sXktFar 17131297
Roviello, G. N., Musumeci, D., Moccia, M., Castiglione, M., Sapio, R., Valente, M., Bucci, E. M., Pedone, C., DabPNA: Design, synthesis, and DNA binding studies (2007) Nucleosides Nucleotides Nucleic Acids, 26, pp. 1307-1310. , 1: CAS: 528: DC%2BD2sXhtl2hurnJ 18066773
Roviello, G. N., Gaetano, S. D., Capasso, D., Cesarani, A., Bucci, E. M., Pedone, C., Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (2009) Amino Acids, , doi: 10. 1007/s00726-009-0361-5
Roviello, G. N., Crescenzo, C., Capasso, D., Di Gaetano, S., Franco, S., Bucci, E. M., Pedone, C., Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/l-arginine-containing nucleopeptides and preliminary RNA interaction studies (2010) Amino Acids, , doi: 10. 1007/S00726-010-0532-4
Shvachkin, Y. P., Mishin, G. P., Korshunova, G. A., Advances and prospects in the chemistry of nucleoaminoacids and nucleopeptides (1982) Russ Chem Rev, 51, pp. 178-188
Simmons, C. G., Pitts, A. E., Mayfield, L. D., Shay, J. W., Corey, D. R., Synthesis and permeability of PNA-peptide conjugates (1997) Bioorg Med Chem Lett, 7, pp. 3001-3007. , 1: CAS: 528: DyaK1cXitVWrsg%3D%3D
Thomson, S. A., Josey, J. A., Cadilla, R., Gaul, M. D., Hassman, C. F., Luzzio, M. J., Fmoc mediated synthesis of peptide nucleic acids (1995) Tetrahedron, 51, pp. 6179-6194. , 1: CAS: 528: DyaK2MXlvFOhtbw%3D
Toure, B. B., Hall, D. G., Natural product synthesis using multicomponent reaction strategies (2009) Chem Rev, 109, pp. 4439-4486. , 1: CAS: 528: DC%2BD1MXmsFamsLg%3D 19480390
Turner, J. J., Jones, S., Fabani, M. M., Ivanova, G., Arzumanov, A. A., Gait, M. J., RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA (2007) Blood Cells Mol Dis, 38, pp. 1-7. , 1: CAS: 528: DC%2BD2sXht1Cjtw%3D%3D 17113327
Van Der Laan, A. C., Van Amsterdam, I., Tesser, G. I., Van Boom, J. H., Kuyl-Yeheskiely, E., Synthesis of chirally pure ornithine based PNA analogues (1998) Nucleoside Nucleotide Nucleic Acid, 17, pp. 219-231
Veselkov, A. G., Demidov, V., Nielsen, P. E., Frank-Kamenetskii, M. D., A new class of genome rare cutters (1996) Nucleic Acids Res, 24, pp. 2483-2487. , 1: CAS: 528: DyaK28XksVyjsb8%3D 8692685
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