Ultrasensitive detection of non-amplified genomic DNA (434 views)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 0, 5-year impact factor: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-80052346181&partnerID=40&md5=abbfa16af69a55ceec132f5181f2e5a0
Keywords: Genomic Dna, Peptide Nucleic Acid, Ultrasensitive, Ultrasensitive Detection, Microsystems, Sensors, Biosensors, Dna Sensing, Pcr-Free, Surface-Plasmon Resonance, Biosensing, Certified Reference Materials, Detection Methods, Direct Detection, Dna Detection, Enhanced Surface, Genetically Modified, Labeling Steps, Selectivity And Sensitivity, Target Sequences, Biomolecules, Dna Sequences, Nanoparticles, Polymerase Chain Reaction, Surface Plasmon Resonance, Complementary Dna, Analytic Method, Controlled Study, Dna Determination, Gene Amplification, Gene Targeting, Image Enhancement, Sensitivity Analysis, Base Sequence, Recombinant, Gold, Metal Nanoparticles, Plants, Soybeans, Statistics, Numerical Data,
Affiliations:
*** IBB - CNR ***
Scuola Superiore di Catania, c/o Dipartimento di Scienze Chimiche, Università di Catania, Catania, Italy
Dipartimento di Chimica Organica Ed Industriale, Università di Parma, Viale G.P. Usberti 17/a, 43100, Parma, Italy
Neotron S.p.a., Stradello Aggazzotti 104, S. Maria di Mugnano, 41010, Modena, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy
Neotron S. p. a., Stradello Aggazzotti 104, I-41010 Modena, Italy
References:
Shi, L., Perkins, R.G., Fang, H., Tong, W., Reproducible and reliable microarray results through quality control: Good laboratory proficiency and appropriate data analysis practices are essential (2008) Curr Opin Biotechnol, 19, pp. 10-1
Grasso, G., D'Agata, R., Zanoli, L., Spoto, G., Microfluidic networks for surface plasmon resonance imaging real-time kinetics experiments (2009) Microchem J, 93, pp. 82-86
Zanoli, L., D'Agata, R., Spoto, G., Surface plasmon-based optical detection of DNA by peptide nucleic acids (2008) Minerva Biotecnologica, 20, pp. 165-174
D'Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G., Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (2008) ChemBioChem, 9, pp. 2067-2070
D'Agata, R., Grasso, G., Spoto, G., Real-time binding kinetics monitored with surface plasmon resonance imaging in a diffusion-free environment (2008) Open Spectrosc J, 1, pp. 1-9
Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R., Development of a peptide nucleic acid array platform for the detection of genetically modified organisms in food (2005) Journal of Agricultural and Food Chemistry, 53 (10), pp. 3958-3962. , DOI 10.1021/jf050016e
Arena, G., Contino, A., Longo, E., Sgarlata, C., Spoto, G., Zito, V., (2004) Chem. Commun., 16, pp. 1812-181
Berdal, K.G., Bøydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
Burns, C., Spendel, W.U., Puckett, S., Pacey, G.E., (2006) Talanta, 69, pp. 873-876
Dos Santos Riccardi, C., Kranz, C., Kowalik, J., Yamanaka, H., Mizaikoff, B., Josowicz, M., (2008) Anal. Chem., 80, pp. 237-245
Gibson, G., (2008) Nat. Rev. Genet., 9, pp. 575-581
(2009), http://ec.europa.eu/food/dyna/gm_register/index_en.cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20.11.09)Goodrich, T.T., Lee, H.J., Corn, R.M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K.C., Freeman, R.G., Hommer, M.B., Natan, M.J., (1995) Anal. Chem., 67, pp. 735-743
Grasso, G., Bush, A.I., D'Agata, R., Rizzarelli, E., Spoto, G., (2009) Eur. Biophys. J., Biophys. Lett., 38, pp. 407-414
Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Yeo, K.J., (2006) J. Mass Spectrom., 41, pp. 1561-1569
Haiss, W., Thanh, N.T.K., Aveyard, J., Fernig, D.G., (2007) Anal. Chem., 79, pp. 4215-4221
He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H.A., Doré, K., Boissinot, M., Bergeron, M.G., Tanguay, R.M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods(2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H.J., Wark, A.W., Corn, A.W., (2006) Langmuir, 22, pp. 5241-5250
Li-Qiang, C., Foerch, R., Knoll, W., (2007) Angew. Chem. Int. Ed., 46, pp. 4944-4947
Minunni, M., Tombelli, S., Mascini, M., (2007) Anal. Lett., 40, pp. 1360-1370
Perkel, J., (2008) Nat. Methods, 5, pp. 447-453
Rosi, N.L., Mirkin, C.A., (2005) Chem. Rev., 105, pp. 1547-1562
Rossi, S., Scaravelli, E., Germini, A., Corradini, R., Fogher, C., Marchelli, R., (2006) Eur. Food Res. Technol., 223, pp. 1-6
Rothenhäusler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
Ruemmele, J.A., Golden, M.S., Gao, Y., Cornelius, E.M., Anderson, M.E., Postelnicu, L., Georgiadis, R.M., (2008) Anal. Chem., 80, pp. 4752-4756
Sassolas, A., Leca-Bouvier, B.D., Blum, L.J., (2008) Chem. Rev., 108, pp. 109-139
Scarano, S., Mascini, M., Turner, A.P.F., Minunni, M., (2009) Biosens. Bioelectron.
Shultz, J.L., Kurunam, D., Shopinski, D., Iqbal, M.J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D.A., (2006) Nucl. Acids Res., 34, pp. D758-D765
Sohni, Y., Kanjilal, S., Kapur, V., (2008) Clin. Biochem., 41, pp. 640-644
Stoeva, S.I., Lee, J., Thaxton, C.S., Mirkin, C.A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306
Storhoff, J.J., Lucas, A.D., Garimella, V., Bao, Y.P., Müller, U.R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K.G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Totsingan, F., Rossi, S., Corradini, R., Tedeschi, T., Sforza, S., Juris, A., Scaravelli, E., Marchelli, R., (2008) Org. Biomol. Chem., 6, pp. 1232-1237
Wark, A.W., Lee, H.J., Corn, R.M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J.-K., Jeong, N., Back, K., Kim, H.M., Jeong, S.C., (2008) Genomics, 92, pp. 52-59
Zhang, N., Appella, D.H., (2007) J. Am. Chem. Soc., 129, pp. 8424-8425
Zhao, W., Brook, M.A., Li, Y.F., (2008) ChemBioChem, 9, pp. 2363-2371
Zhu, D., Tang, Y., Xing, D., Chen, W.R., (2008) Anal. Chem., 80, pp. 3566-3571
Berdal, K. G., B ydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
(2009), http: //ec. europa. eu/food/dyna/gm_register/index_en. cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20. 11. 09) Goodrich, T. T., Lee, H. J., Corn, R. M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K. C., Freeman, R. G., Hommer, M. B., Natan, M. J., (1995) Anal. Chem., 67, pp. 735-743
He, L., Musick, M. D., Nicewarner, S. R., Salinas, F. G., Benkovic, S. J., Natan, M. J., Keating, C. D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H. A., Dor, K., Boissinot, M., Bergeron, M. G., Tanguay, R. M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods (2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H. J., Wark, A. W., Corn, A. W., (2006) Langmuir, 22, pp. 5241-5250
Rosi, N. L., Mirkin, C. A., (2005) Chem. Rev., 105, pp. 1547-1562
Rothenh usler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
Ruemmele, J. A., Golden, M. S., Gao, Y., Cornelius, E. M., Anderson, M. E., Postelnicu, L., Georgiadis, R. M., (2008) Anal. Chem., 80, pp. 4752-4756
Shultz, J. L., Kurunam, D., Shopinski, D., Iqbal, M. J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D. A., (2006) Nucl. Acids Res., 34, pp. D758-D765
Stoeva, S. I., Lee, J., Thaxton, C. S., Mirkin, C. A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306
Storhoff, J. J., Lucas, A. D., Garimella, V., Bao, Y. P., M ller, U. R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K. G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Wark, A. W., Lee, H. J., Corn, R. M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J. -K., Jeong, N., Back, K., Kim, H. M., Jeong, S. C., (2008) Genomics, 92, pp. 52-59
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 0, 5-year impact factor: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-80052346181&partnerID=40&md5=abbfa16af69a55ceec132f5181f2e5a0
Keywords: Genomic Dna, Peptide Nucleic Acid, Ultrasensitive, Ultrasensitive Detection, Microsystems, Sensors, Biosensors, Dna Sensing, Pcr-Free, Surface-Plasmon Resonance, Biosensing, Certified Reference Materials, Detection Methods, Direct Detection, Dna Detection, Enhanced Surface, Genetically Modified, Labeling Steps, Selectivity And Sensitivity, Target Sequences, Biomolecules, Dna Sequences, Nanoparticles, Polymerase Chain Reaction, Surface Plasmon Resonance, Complementary Dna, Analytic Method, Controlled Study, Dna Determination, Gene Amplification, Gene Targeting, Image Enhancement, Sensitivity Analysis, Base Sequence, Recombinant, Gold, Metal Nanoparticles, Plants, Soybeans, Statistics, Numerical Data,
Affiliations:
*** IBB - CNR ***
Scuola Superiore di Catania, c/o Dipartimento di Scienze Chimiche, Università di Catania, Catania, Italy
Dipartimento di Chimica Organica Ed Industriale, Università di Parma, Viale G.P. Usberti 17/a, 43100, Parma, Italy
Neotron S.p.a., Stradello Aggazzotti 104, S. Maria di Mugnano, 41010, Modena, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy
Neotron S. p. a., Stradello Aggazzotti 104, I-41010 Modena, Italy
References:
Shi, L., Perkins, R.G., Fang, H., Tong, W., Reproducible and reliable microarray results through quality control: Good laboratory proficiency and appropriate data analysis practices are essential (2008) Curr Opin Biotechnol, 19, pp. 10-1
Grasso, G., D'Agata, R., Zanoli, L., Spoto, G., Microfluidic networks for surface plasmon resonance imaging real-time kinetics experiments (2009) Microchem J, 93, pp. 82-86
Zanoli, L., D'Agata, R., Spoto, G., Surface plasmon-based optical detection of DNA by peptide nucleic acids (2008) Minerva Biotecnologica, 20, pp. 165-174
D'Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G., Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (2008) ChemBioChem, 9, pp. 2067-2070
D'Agata, R., Grasso, G., Spoto, G., Real-time binding kinetics monitored with surface plasmon resonance imaging in a diffusion-free environment (2008) Open Spectrosc J, 1, pp. 1-9
Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R., Development of a peptide nucleic acid array platform for the detection of genetically modified organisms in food (2005) Journal of Agricultural and Food Chemistry, 53 (10), pp. 3958-3962. , DOI 10.1021/jf050016e
Arena, G., Contino, A., Longo, E., Sgarlata, C., Spoto, G., Zito, V., (2004) Chem. Commun., 16, pp. 1812-181
Berdal, K.G., Bøydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
Burns, C., Spendel, W.U., Puckett, S., Pacey, G.E., (2006) Talanta, 69, pp. 873-876
Dos Santos Riccardi, C., Kranz, C., Kowalik, J., Yamanaka, H., Mizaikoff, B., Josowicz, M., (2008) Anal. Chem., 80, pp. 237-245
Gibson, G., (2008) Nat. Rev. Genet., 9, pp. 575-581
(2009), http://ec.europa.eu/food/dyna/gm_register/index_en.cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20.11.09)Goodrich, T.T., Lee, H.J., Corn, R.M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K.C., Freeman, R.G., Hommer, M.B., Natan, M.J., (1995) Anal. Chem., 67, pp. 735-743
Grasso, G., Bush, A.I., D'Agata, R., Rizzarelli, E., Spoto, G., (2009) Eur. Biophys. J., Biophys. Lett., 38, pp. 407-414
Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Yeo, K.J., (2006) J. Mass Spectrom., 41, pp. 1561-1569
Haiss, W., Thanh, N.T.K., Aveyard, J., Fernig, D.G., (2007) Anal. Chem., 79, pp. 4215-4221
He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H.A., Doré, K., Boissinot, M., Bergeron, M.G., Tanguay, R.M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods(2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H.J., Wark, A.W., Corn, A.W., (2006) Langmuir, 22, pp. 5241-5250
Li-Qiang, C., Foerch, R., Knoll, W., (2007) Angew. Chem. Int. Ed., 46, pp. 4944-4947
Minunni, M., Tombelli, S., Mascini, M., (2007) Anal. Lett., 40, pp. 1360-1370
Perkel, J., (2008) Nat. Methods, 5, pp. 447-453
Rosi, N.L., Mirkin, C.A., (2005) Chem. Rev., 105, pp. 1547-1562
Rossi, S., Scaravelli, E., Germini, A., Corradini, R., Fogher, C., Marchelli, R., (2006) Eur. Food Res. Technol., 223, pp. 1-6
Rothenhäusler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
Ruemmele, J.A., Golden, M.S., Gao, Y., Cornelius, E.M., Anderson, M.E., Postelnicu, L., Georgiadis, R.M., (2008) Anal. Chem., 80, pp. 4752-4756
Sassolas, A., Leca-Bouvier, B.D., Blum, L.J., (2008) Chem. Rev., 108, pp. 109-139
Scarano, S., Mascini, M., Turner, A.P.F., Minunni, M., (2009) Biosens. Bioelectron.
Shultz, J.L., Kurunam, D., Shopinski, D., Iqbal, M.J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D.A., (2006) Nucl. Acids Res., 34, pp. D758-D765
Sohni, Y., Kanjilal, S., Kapur, V., (2008) Clin. Biochem., 41, pp. 640-644
Stoeva, S.I., Lee, J., Thaxton, C.S., Mirkin, C.A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306
Storhoff, J.J., Lucas, A.D., Garimella, V., Bao, Y.P., Müller, U.R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K.G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Totsingan, F., Rossi, S., Corradini, R., Tedeschi, T., Sforza, S., Juris, A., Scaravelli, E., Marchelli, R., (2008) Org. Biomol. Chem., 6, pp. 1232-1237
Wark, A.W., Lee, H.J., Corn, R.M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J.-K., Jeong, N., Back, K., Kim, H.M., Jeong, S.C., (2008) Genomics, 92, pp. 52-59
Zhang, N., Appella, D.H., (2007) J. Am. Chem. Soc., 129, pp. 8424-8425
Zhao, W., Brook, M.A., Li, Y.F., (2008) ChemBioChem, 9, pp. 2363-2371
Zhu, D., Tang, Y., Xing, D., Chen, W.R., (2008) Anal. Chem., 80, pp. 3566-3571
Berdal, K. G., B ydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
(2009), http: //ec. europa. eu/food/dyna/gm_register/index_en. cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20. 11. 09) Goodrich, T. T., Lee, H. J., Corn, R. M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K. C., Freeman, R. G., Hommer, M. B., Natan, M. J., (1995) Anal. Chem., 67, pp. 735-743
He, L., Musick, M. D., Nicewarner, S. R., Salinas, F. G., Benkovic, S. J., Natan, M. J., Keating, C. D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H. A., Dor, K., Boissinot, M., Bergeron, M. G., Tanguay, R. M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods (2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H. J., Wark, A. W., Corn, A. W., (2006) Langmuir, 22, pp. 5241-5250
Rosi, N. L., Mirkin, C. A., (2005) Chem. Rev., 105, pp. 1547-1562
Rothenh usler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
Ruemmele, J. A., Golden, M. S., Gao, Y., Cornelius, E. M., Anderson, M. E., Postelnicu, L., Georgiadis, R. M., (2008) Anal. Chem., 80, pp. 4752-4756
Shultz, J. L., Kurunam, D., Shopinski, D., Iqbal, M. J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D. A., (2006) Nucl. Acids Res., 34, pp. D758-D765
Stoeva, S. I., Lee, J., Thaxton, C. S., Mirkin, C. A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306
Storhoff, J. J., Lucas, A. D., Garimella, V., Bao, Y. P., M ller, U. R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K. G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Wark, A. W., Lee, H. J., Corn, R. M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J. -K., Jeong, N., Back, K., Kim, H. M., Jeong, S. C., (2008) Genomics, 92, pp. 52-59
Ultrasensitive detection of non-amplified genomic DNA
The combined use of peptide nucleic acid probes and ultrasensitive nanoparticle-enhanced SPRI detection is shown to allow the ultra-sensitive detection of non-amplified genomic DNA. © 2011 Springer Science+Business Media B.V.
The combined use of peptide nucleic acid probes and ultrasensitive nanoparticle-enhanced SPRI detection is shown to allow the ultra-sensitive detection of non-amplified genomic DNA. © 2011 Springer Science+Business Media B.V.
Ultrasensitive detection of non-amplified genomic DNA
| ▼ Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications |
Ultrasensitive detection of non-amplified genomic DNA
Other filter: ([btitle,keywords] "Genomic Dna" OR [bti ...
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Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
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Lanzillo R, Liuzzi R, Vallefuoco L, Moccia M, Amato L, Vacca G, Vacchiano V, Portella G, Brescia Morra V
* JC virus antibody index in natalizumab-treated patients: correlations with John Cunningham virus DNA and C-reactive protein level (329 views)
Ther Clin Risk Manag (ISSN: 1178-203x), 2014 Oct 9; 10: 807-814.
Impact Factor: 1.469
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Olgiati S, De Rosa A, Quadri M, Criscuolo C, Breedveld GJ, Picillo M, Pappata S, Quarantelli M, Barone P, De Michele G, Bonifati V
* Park20 Caused By Synj1 Homozygous Arg258gln Mutation In A New Italian Family (492 views)
Neurogenetics (ISSN: 1364-6745, 1364-6753), 2014 Aug; 15(3): 183-188.
Impact Factor: 2.884
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Musumeci D, Roviello GN, Montesarchio D
* An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies (559 views)
Pharmacol Ther (ISSN: 0163-7258, 0163-7258linking), 2014 Mar; 141(3): 347-357.
Impact Factor: 9.723
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Autiero I, Saviano M, Langella E
* Molecular Dynamics Simulations Of Pna-Pna And Pna-Dna Duplexes By The Use Of New Parameters Implemented In The Gromacs Package: A Conformational And Dynamics Study (723 views)
Phys Chem Chem Phys (ISSN: 1463-9076, 1463-3907, 1463-9084electronic), 2014; 16(5): 1868-1874.
Impact Factor: 4.493
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Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Synthesis of a thymine-functionalized nucleoamino acid for the solid phase assembly of cationic nucleopeptides (486 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2013 Oct; 45(4): 779-784.
Impact Factor: 3.653
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Quadri M, Fang M, Picillo M, Olgiati S, Breedveld Gj Graafland J, Wu B, Xu F, Erro R, Amboni M, Pappata S, Quarantelli M, Annesi G, Quattrone A, Chien Hf Barbosa ER, International Parkinsonism Genetics Network Oostra Ba Barone P, Wang J, Bonifati V
* Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism (401 views)
Hum Mutat (ISSN: 1059-7794, 1098-1004, 1098-1004electronic), 2013 Sep; 34(9): 1208-1215.
Impact Factor: 5.122
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Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G
* Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices (360 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 615-624.
Impact Factor: 3.578
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (444 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
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Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (439 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
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Avitabile C, Moggio L, Malgieri G, Capasso D, Di Gaetano S, Saviano M, Pedone C, Romanelli A
* Gamma Sulphate Pna (pna S): Highly Selective Dna Binding Molecule Showing Promising Antigene Activity (451 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2012 May 7; 7(5): e35774-e35774.
Impact Factor: 3.73
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D'Agata R, Spoto G
* Artificial DNA and surface plasmon resonance (554 views)
Artificial Dna Pna & Xna (ISSN: 1949-095x), 2012 Apr; 3(2): N/D-N/D.
Impact Factor: 0
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Avitabile C, Saviano M, D'Andrea LD, Bianchi N, Fabbri E, Brognara E, Gambari R, Romanelli A
* Targeting pre-miRNA by peptide nucleic acids: a new strategy to interfere in the miRNA maturation (545 views)
Artif Dna Pna Xnaartificial Dna Pna & Xna (ISSN: 1949-9096, 1949-0968, 1949-095x), 2012 Apr; 3(2): 88-96.
Impact Factor: 0
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Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (402 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.
Impact Factor: 3.659
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D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R
* Direct Detection of Point Mutations in Nonamplified Human Genomic DNA (792 views)
Analytical Chemistry (ISSN: 0003-2700), 2011 Nov 15; 83(22): 8711-8717.
Impact Factor: 5.856
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (531 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
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Musumeci D, Bucci EM, Roviello GN, Sapio R, Valente M, Moccia M, Bianchi ME, Pedone C
* DNA-based strategies for blocking HMGB1 cytokine activity: Design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes (481 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1742-1752.
Impact Factor: 3.534
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Roviello GN, Ricci A, Bucci EM, Pedone C
* Synthesis, biological evaluation and supramolecular assembly of novel analogues of peptidyl nucleosides (1528 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1773-1778.
Impact Factor: 3.534
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Evidences for supramolecular organization of nucleopeptides: Synthesis, spectroscopic and biological studies of a novel dithymine l-serine tetrapeptide (578 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 Apr; 7(4): 1073-1080.
Impact Factor: 3.534
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Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A
* Gamma-Hydroxymethyl Pnas: Synthesis, Interaction With Dna And Inhibition Of Protein/Dna Interactions (377 views)
Bioorg Chem, 2010 Sep; 38(5): 196-201.
Impact Factor: 2.141
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Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (464 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
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Avitabile C, Moggio L, D'Andrea LD, Pedone C, Romanelli A
* Development of an efficient and low-cost protocol for the manual PNA synthesis by Fmoc chemistry (482 views)
Tetrahedron Lett (ISSN: 0040-4039), 2010 Jul 21; 51(29): 3716-3718.
Impact Factor: 2.618
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (425 views)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Impact Factor: 5.361
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Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (597 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
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Roviello GN, Gröschel S, Pedone C, Diederichsen U
* Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (804 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Impact Factor: 4.106
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Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (443 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
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Roviello GN, Musumeci D, Pedone C, Bucci EM
* Synthesis, Characterization And Hybridization Studies Of An Alternate Nucleo-Epsilon/Gamma-Peptide: Complexes Formation With Natural Nucleic Acids (494 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jan; 38(1): 103-111.
Impact Factor: 4.106
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Detection Of Non Amplified Genomic Dna By Advanced Spri Methods (224 views)
Chimica & L Industria, 2010; 7: 140-145.
Impact Factor: 0
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D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (362 views)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
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D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (298 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
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Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (913 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
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Roviello GN, Musumeci D, Moccia M, Castiglione M, Cesarani A, Bucci EM, Saviano M, Pedone C, Benedetti E
* Evidences Of Complex Formation Between Daba-Based Nucleo-Gamma-Peptides With Alternate Configuration Backbone (431 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 147-154.
Impact Factor: 1.807
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Roviello GN, Musumeci D, Castiglione M, Bucci EM, Pedone C, Benedetti E
* Solid Phase Synthesis And Rna-Binding Studies Of A Serum-Resistant Nucleo-Epsilon-Peptide (435 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 155-160.
Impact Factor: 1.807
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Roviello GN, Musumeci D, Bucci EM, Castiglione M, Cesarani A, Pedone C, Piccialli G
* Evidences for complex formation between l-dabPNA and aegPNA (304 views)
Bioorg Med Chem Lett (ISSN: 0960-894x, 1464-3405, 1464-3405electronic), 2008 Sep 1; 18(17): 4757-4760.
Impact Factor: 2.531
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D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (412 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
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Pensato S, D'Andrea LD, Pedone C, Romanelli A
* New synthetic route to gamma-mercaptomethyl PNA monomers (406 views)
Synth Commun Synthetic Communications (ISSN: 0039-7911), 2008; 38(15): 2499-2506.
Impact Factor: 0.981
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Breveglieri G, Pensato S, Salvatori F, Saviano M, Pedone C, Romanelli A, Gambari R
* PNA-mediated alteration of mRNA splicing (349 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 175-181.
Impact Factor: 0.1
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Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R
* PNAs targeting the "RNA world": Micro RNA next? (401 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 183-188.
Impact Factor: 0.1
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Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (262 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
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Pensato S, Saviano M, Romanelli A
* New peptide nucleic acid analogues: synthesis and applications (606 views)
Expert Opinion On Biological Therapy (ISSN: 1471-2598), 2007 Sep; 7(8): 1219-1232.
Impact Factor: 2.815
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Roviello GN, Musumeci D, Moccia M, Castiglione M, Sapio R, Valente M, Bucci EM, Perretta G, Pedone C
* Dabpna: Design, Synthesis And Nucleic Acids Binding Studies (430 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1307-1310.
Impact Factor: 0.723
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Moccia M, Musumeci D, Valente M, Roviello GN, Sapio R, Pedone C, Bucci EM
* Thermodynamic studies on PNA and PNA/DNA dendrimer formation (242 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1173-1176.
Impact Factor: 0.723
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Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (493 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
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Musumeci D, Valente M, Capasso D, Palumbo R, Gorlach M, Schmidtke M, Zell R, Roviello GN, Sapio R, Pedone C, Bucci EM
* A short PNA targeting coxsackievirus B3 5′-nontranslated region prevents virus-induced cytolysis (423 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Mar; 12(3): 161-170.
Impact Factor: 1.801
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Zannetti A, Del Vecchio S, Romanelli A, Scala S, Saviano M, Cali' G, Stoppelli MP, Pedone C, Salvatore M
* Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells (512 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2005 Nov 1; 70(9): 1277-1287.
Impact Factor: 3.617
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Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (439 views)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
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Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (509 views)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
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Mischiati C, Sereni A, Finotti A, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Pedone C, Borgatti M, Gambari R
* Complexation to cationic microspheres of double-stranded peptide nucleic acid-DNA chimeras exhibiting decoy activity (378 views)
Journal Of Biomedical Science (ISSN: 1021-7770), 2004 Sep; 11(5): 697-704.
Impact Factor: 1.567
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Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R
* Peptide nucleic acid-DNA decoy chimeras targeting NF-kappa B transcription factors: Induction of apoptosis in human primary osteoclasts (312 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2004 Sep; 14(2): 145-152.
Impact Factor: 3.19
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Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (393 views)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
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Musumeci D, Roviello GN, Valente M, Sapio R, Pedone C, Bucci EM
* New synthesis of PNA-3′DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (433 views)
Biopolymers, 2004; 76(6): 535-542.
Impact Factor: 2.248
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Menchise V, De Simone G, Tedeschi T, Corradini R, Sforza S, Marchelli R, Capasso D, Saviano M, Pedone C
* Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex (553 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2003 Oct 14; 100(21): 12021-12026.
Impact Factor: 10.272
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Borgatti M, Lampronti I, Romanelli A, Pedone C, Saviano M, Bianchi N, Mischiati C, Gambari R
* Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites (600 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2003 Feb 28; 278(9): 7500-7509.
Impact Factor: 6.482
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Borgatti M, Romanelli A, Saviano M, Pedone C, Lampronti I, Breda L, Nastruzzi C, Bianchi N, Mischiati C, Gambari R
* Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum (430 views)
Oncology Research (ISSN: 0965-0407), 2003; 13(5): 279-287.
Impact Factor: 1.794
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Gambari R, Borgatti M, Romanelli A, Capasso D, Saviano M, Bianchi N, Lampronti I, Mischiati C, Pedone C
* Transcription factor decoy (TFD) activity of peptide nucleic acids (PNA)-DNA chimeras (270 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2003; 12(Supplement1): N/D-N/D.
Impact Factor: 1.94
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Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (431 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
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Menchise V, De Simone G, Corradini R, Sforza S, Sorrentino N, Romanelli A, Saviano M, Pedone C
* Crystallization and preliminary X-ray diffraction studies of a D-lysine-based chiral PNA-DNA duplex (328 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002 Mar; 58(3): 553-555.
Impact Factor: 1.76
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (435 views)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 2.849
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (436 views)
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 4.779
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Saviano M, Romanelli A, Bucci E, Pedone C, Mischiati C, Bianchi N, Feriotto G, Borgatti M, Gambari R
Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-κB binding sites (493 views)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2000 Dec; 18(3): 353-362.
Impact Factor: 1.826
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* Chiral Fibers Formation Upon Assembly of Tetraphenylalanine Peptide Conjugated to a PNA Dimer (2 views)
Chemistry (ISSN: 0947-6539linking), 2022 Jul 1; 28 (37 ): e202200693-N/D.
Impact Factor:
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Diaferia C, Avitabile C, Leone M, Gallo E, Saviano M, Accardo A, Romanelli A
* Diphenylalanine Motif Drives Self-Assembling in Hybrid PNA-Peptide Conjugates (15 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2021 Oct 13; 27(57): 14307-14316.
Impact Factor: 5.236
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Scognamiglio PL, Platella C, Napolitano E, Musumeci D, Roviello GN
* From Prebiotic Chemistry to Supramolecular Biomedical Materials: Exploring the Properties of Self-Assembling Nucleobase-Containing Peptides (28 views)
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Jun 10; 26(12): 3558-3558.
Impact Factor: 4.411
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Moccia M, Mercurio FA, Langella E, Piacenti V, Leone M, Adamo MFA, Saviano M
* Structural Insights on Tiny Peptide Nucleic Acid (PNA) Analogues of miRNA-34a: An in silico and Experimental Integrated Approach (74 views)
Front Chem (ISSN: 2296-2646linking), 2020 Nov 23; 8: 568575-568575.
Impact Factor: 3.693
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Avitabile C, Diaferia C, Roviello V, Altamura D, Giannini C, Vitagliano L, Accardo A, Romanelli A
* Fluorescence and Morphology of Self-Assembled Nucleobases and Their Diphenylalanine Hybrid Aggregates (232 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2019 Nov 22; 25(65): 14850-14857.
Impact Factor: 5.476
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Piacenti V, Langella E, Autiero I, Nolan JC, Piskareva O, Adamo MFA, Saviano M, Moccia M
* A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a (222 views)
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2019 Oct; 91: 103165-103165.
Impact Factor: 3.9
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Avitabile C, Diaferia C, Della Ventura B, Mercurio FA, Leone M, Roviello V, Saviano M, Velotta R, Morelli G, Accardo A, Romanelli A
* Self-Assembling of Fmoc-GC Peptide Nucleic Acid Dimers into Highly Fluorescent Aggregates (891 views)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Mar 26; 24(18): 4729-4735.
Impact Factor: 5.476
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Piras L, Avitabile C, D'Andrea LD, Saviano M, Romanelli A
* Detection of oligonucleotides by PNA-peptide conjugates recognizing the biarsenical fluorescein complex FlAsH-EDT2 (280 views)
Biochem Bioph Res Co (ISSN: 0006-291x), 2017 Sep 15; N/D: N/D-N/D.
Impact Factor: 2.559
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Ringhieri P, Avitabile C, Saviano M, Morelli G, Romanelli A, Accardo A
* The influence of liposomal formulation on the incorporation and retention of PNA oligomers (241 views)
Colloid Surface B (ISSN: 0927-7765), 2016; 145: 462-469.
Impact Factor: 3.887
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Autiero I, Saviano M, Langella E
* Conformational studies of chiral D-Lys-PNA and achiral PNA system in binding with DNA or RNA through a molecular dynamics approach (496 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015 Feb 16; 91: 109-117.
Impact Factor: 3.902
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Avitabile C, Accardo A, Ringhieri P, Morelli G, Saviano M, Montagner G, Fabbri E, Gallerani E, Gambari R, Romanelli A
* Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery (481 views)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
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Lanzillo R, Liuzzi R, Vallefuoco L, Moccia M, Amato L, Vacca G, Vacchiano V, Portella G, Brescia Morra V
* JC virus antibody index in natalizumab-treated patients: correlations with John Cunningham virus DNA and C-reactive protein level (329 views)
Ther Clin Risk Manag (ISSN: 1178-203x), 2014 Oct 9; 10: 807-814.
Impact Factor: 1.469
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Olgiati S, De Rosa A, Quadri M, Criscuolo C, Breedveld GJ, Picillo M, Pappata S, Quarantelli M, Barone P, De Michele G, Bonifati V
* Park20 Caused By Synj1 Homozygous Arg258gln Mutation In A New Italian Family (492 views)
Neurogenetics (ISSN: 1364-6745, 1364-6753), 2014 Aug; 15(3): 183-188.
Impact Factor: 2.884
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Musumeci D, Roviello GN, Montesarchio D
* An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies (559 views)
Pharmacol Ther (ISSN: 0163-7258, 0163-7258linking), 2014 Mar; 141(3): 347-357.
Impact Factor: 9.723
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Autiero I, Saviano M, Langella E
* Molecular Dynamics Simulations Of Pna-Pna And Pna-Dna Duplexes By The Use Of New Parameters Implemented In The Gromacs Package: A Conformational And Dynamics Study (723 views)
Phys Chem Chem Phys (ISSN: 1463-9076, 1463-3907, 1463-9084electronic), 2014; 16(5): 1868-1874.
Impact Factor: 4.493
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Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Synthesis of a thymine-functionalized nucleoamino acid for the solid phase assembly of cationic nucleopeptides (486 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2013 Oct; 45(4): 779-784.
Impact Factor: 3.653
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Quadri M, Fang M, Picillo M, Olgiati S, Breedveld Gj Graafland J, Wu B, Xu F, Erro R, Amboni M, Pappata S, Quarantelli M, Annesi G, Quattrone A, Chien Hf Barbosa ER, International Parkinsonism Genetics Network Oostra Ba Barone P, Wang J, Bonifati V
* Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism (401 views)
Hum Mutat (ISSN: 1059-7794, 1098-1004, 1098-1004electronic), 2013 Sep; 34(9): 1208-1215.
Impact Factor: 5.122
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Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G
* Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices (360 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 615-624.
Impact Factor: 3.578
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (444 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
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Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (439 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
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Avitabile C, Moggio L, Malgieri G, Capasso D, Di Gaetano S, Saviano M, Pedone C, Romanelli A
* Gamma Sulphate Pna (pna S): Highly Selective Dna Binding Molecule Showing Promising Antigene Activity (451 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2012 May 7; 7(5): e35774-e35774.
Impact Factor: 3.73
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D'Agata R, Spoto G
* Artificial DNA and surface plasmon resonance (554 views)
Artificial Dna Pna & Xna (ISSN: 1949-095x), 2012 Apr; 3(2): N/D-N/D.
Impact Factor: 0
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Avitabile C, Saviano M, D'Andrea LD, Bianchi N, Fabbri E, Brognara E, Gambari R, Romanelli A
* Targeting pre-miRNA by peptide nucleic acids: a new strategy to interfere in the miRNA maturation (545 views)
Artif Dna Pna Xnaartificial Dna Pna & Xna (ISSN: 1949-9096, 1949-0968, 1949-095x), 2012 Apr; 3(2): 88-96.
Impact Factor: 0
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Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (402 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.
Impact Factor: 3.659
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D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R
* Direct Detection of Point Mutations in Nonamplified Human Genomic DNA (792 views)
Analytical Chemistry (ISSN: 0003-2700), 2011 Nov 15; 83(22): 8711-8717.
Impact Factor: 5.856
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (531 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
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Musumeci D, Bucci EM, Roviello GN, Sapio R, Valente M, Moccia M, Bianchi ME, Pedone C
* DNA-based strategies for blocking HMGB1 cytokine activity: Design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes (481 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1742-1752.
Impact Factor: 3.534
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Roviello GN, Ricci A, Bucci EM, Pedone C
* Synthesis, biological evaluation and supramolecular assembly of novel analogues of peptidyl nucleosides (1528 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1773-1778.
Impact Factor: 3.534
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Roviello GN, Musumeci D, Bucci EM, Pedone C
* Evidences for supramolecular organization of nucleopeptides: Synthesis, spectroscopic and biological studies of a novel dithymine l-serine tetrapeptide (578 views)
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 Apr; 7(4): 1073-1080.
Impact Factor: 3.534
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Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A
* Gamma-Hydroxymethyl Pnas: Synthesis, Interaction With Dna And Inhibition Of Protein/Dna Interactions (377 views)
Bioorg Chem, 2010 Sep; 38(5): 196-201.
Impact Factor: 2.141
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Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (464 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
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Avitabile C, Moggio L, D'Andrea LD, Pedone C, Romanelli A
* Development of an efficient and low-cost protocol for the manual PNA synthesis by Fmoc chemistry (482 views)
Tetrahedron Lett (ISSN: 0040-4039), 2010 Jul 21; 51(29): 3716-3718.
Impact Factor: 2.618
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (425 views)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Impact Factor: 5.361
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Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (597 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
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Roviello GN, Gröschel S, Pedone C, Diederichsen U
* Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (804 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Impact Factor: 4.106
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Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (443 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
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Roviello GN, Musumeci D, Pedone C, Bucci EM
* Synthesis, Characterization And Hybridization Studies Of An Alternate Nucleo-Epsilon/Gamma-Peptide: Complexes Formation With Natural Nucleic Acids (494 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jan; 38(1): 103-111.
Impact Factor: 4.106
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Detection Of Non Amplified Genomic Dna By Advanced Spri Methods (224 views)
Chimica & L Industria, 2010; 7: 140-145.
Impact Factor: 0
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D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (362 views)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
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D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (298 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
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Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (913 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
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Roviello GN, Musumeci D, Moccia M, Castiglione M, Cesarani A, Bucci EM, Saviano M, Pedone C, Benedetti E
* Evidences Of Complex Formation Between Daba-Based Nucleo-Gamma-Peptides With Alternate Configuration Backbone (431 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 147-154.
Impact Factor: 1.807
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Roviello GN, Musumeci D, Castiglione M, Bucci EM, Pedone C, Benedetti E
* Solid Phase Synthesis And Rna-Binding Studies Of A Serum-Resistant Nucleo-Epsilon-Peptide (435 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 155-160.
Impact Factor: 1.807
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Roviello GN, Musumeci D, Bucci EM, Castiglione M, Cesarani A, Pedone C, Piccialli G
* Evidences for complex formation between l-dabPNA and aegPNA (304 views)
Bioorg Med Chem Lett (ISSN: 0960-894x, 1464-3405, 1464-3405electronic), 2008 Sep 1; 18(17): 4757-4760.
Impact Factor: 2.531
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D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (412 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
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Pensato S, D'Andrea LD, Pedone C, Romanelli A
* New synthetic route to gamma-mercaptomethyl PNA monomers (406 views)
Synth Commun Synthetic Communications (ISSN: 0039-7911), 2008; 38(15): 2499-2506.
Impact Factor: 0.981
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Breveglieri G, Pensato S, Salvatori F, Saviano M, Pedone C, Romanelli A, Gambari R
* PNA-mediated alteration of mRNA splicing (349 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 175-181.
Impact Factor: 0.1
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Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R
* PNAs targeting the "RNA world": Micro RNA next? (401 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 183-188.
Impact Factor: 0.1
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Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (262 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
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Pensato S, Saviano M, Romanelli A
* New peptide nucleic acid analogues: synthesis and applications (606 views)
Expert Opinion On Biological Therapy (ISSN: 1471-2598), 2007 Sep; 7(8): 1219-1232.
Impact Factor: 2.815
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Roviello GN, Musumeci D, Moccia M, Castiglione M, Sapio R, Valente M, Bucci EM, Perretta G, Pedone C
* Dabpna: Design, Synthesis And Nucleic Acids Binding Studies (430 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1307-1310.
Impact Factor: 0.723
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Moccia M, Musumeci D, Valente M, Roviello GN, Sapio R, Pedone C, Bucci EM
* Thermodynamic studies on PNA and PNA/DNA dendrimer formation (242 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1173-1176.
Impact Factor: 0.723
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Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (493 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
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Musumeci D, Valente M, Capasso D, Palumbo R, Gorlach M, Schmidtke M, Zell R, Roviello GN, Sapio R, Pedone C, Bucci EM
* A short PNA targeting coxsackievirus B3 5′-nontranslated region prevents virus-induced cytolysis (423 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Mar; 12(3): 161-170.
Impact Factor: 1.801
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Zannetti A, Del Vecchio S, Romanelli A, Scala S, Saviano M, Cali' G, Stoppelli MP, Pedone C, Salvatore M
* Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells (512 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2005 Nov 1; 70(9): 1277-1287.
Impact Factor: 3.617
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Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (439 views)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
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Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (509 views)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
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Mischiati C, Sereni A, Finotti A, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Pedone C, Borgatti M, Gambari R
* Complexation to cationic microspheres of double-stranded peptide nucleic acid-DNA chimeras exhibiting decoy activity (378 views)
Journal Of Biomedical Science (ISSN: 1021-7770), 2004 Sep; 11(5): 697-704.
Impact Factor: 1.567
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Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R
* Peptide nucleic acid-DNA decoy chimeras targeting NF-kappa B transcription factors: Induction of apoptosis in human primary osteoclasts (312 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2004 Sep; 14(2): 145-152.
Impact Factor: 3.19
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Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (393 views)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
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Musumeci D, Roviello GN, Valente M, Sapio R, Pedone C, Bucci EM
* New synthesis of PNA-3′DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (433 views)
Biopolymers, 2004; 76(6): 535-542.
Impact Factor: 2.248
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Menchise V, De Simone G, Tedeschi T, Corradini R, Sforza S, Marchelli R, Capasso D, Saviano M, Pedone C
* Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex (553 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2003 Oct 14; 100(21): 12021-12026.
Impact Factor: 10.272
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Borgatti M, Lampronti I, Romanelli A, Pedone C, Saviano M, Bianchi N, Mischiati C, Gambari R
* Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites (600 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2003 Feb 28; 278(9): 7500-7509.
Impact Factor: 6.482
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Borgatti M, Romanelli A, Saviano M, Pedone C, Lampronti I, Breda L, Nastruzzi C, Bianchi N, Mischiati C, Gambari R
* Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum (430 views)
Oncology Research (ISSN: 0965-0407), 2003; 13(5): 279-287.
Impact Factor: 1.794
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Gambari R, Borgatti M, Romanelli A, Capasso D, Saviano M, Bianchi N, Lampronti I, Mischiati C, Pedone C
* Transcription factor decoy (TFD) activity of peptide nucleic acids (PNA)-DNA chimeras (270 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2003; 12(Supplement1): N/D-N/D.
Impact Factor: 1.94
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Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (431 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
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Menchise V, De Simone G, Corradini R, Sforza S, Sorrentino N, Romanelli A, Saviano M, Pedone C
* Crystallization and preliminary X-ray diffraction studies of a D-lysine-based chiral PNA-DNA duplex (328 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002 Mar; 58(3): 553-555.
Impact Factor: 1.76
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (435 views)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 2.849
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Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (436 views)
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 4.779
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Saviano M, Romanelli A, Bucci E, Pedone C, Mischiati C, Bianchi N, Feriotto G, Borgatti M, Gambari R
Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-κB binding sites (493 views)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2000 Dec; 18(3): 353-362.
Impact Factor: 1.826
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70 Records (65 excluding Abstracts).
Total impact factor: 217.281 (207.859 excluding Abstracts).
Total 5 year impact factor: 228.514 (215.579 excluding Abstracts).
Total impact factor: 217.281 (207.859 excluding Abstracts).
Total 5 year impact factor: 228.514 (215.579 excluding Abstracts).
434 views. Last view on Wednesday 31 May 2023, 8:47:47
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