Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide(675 views) Di Fiore A, Monti SM, Hilvo M, Parkkila S, Romano V, Scaloni A, Pedone C, Scozzafava A, Supuran CT, De Simone G
Istituto di Biostrutture e Bioimmagini-CNR, 80134 Naples, Italy.
Institute of Medical Technology and School of Medicine, University of Tampere and Tampere University Hospital, University of Tampere, Tampere, Finland
Laboratorio di Proteomica e Spettrometria di Massa, ISPAAM-CNR, 80147 Naples, Italy
Università degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica, 50019 Sesto Fiorentino (Florence), Italy
Universit degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica, 50019 Sesto Fiorentino (Florence), Italy
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Supuran, C. T., Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators (2008) Nat Rev Drug Discov, 7, pp. 168-18
Lehtonen, J. M., Shen, B., Vihinen, M., Casini, A., Scozzafava, A., Supuran, C. T., Parkkila, A. -K., Parkkila, S., Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family (2004) J Biol Chem, 279, pp. 2719-2727
Supuran, C. T., Scozzafava, A., Casini, A., Carbonic anhydrase inhibitors (2003) Med Res Rev, 23, pp. 146-189
6: 921-936Hilvo, M., Rafajov, M., Pastorekov, S., Pastorek, J., Parkkila, S., Expression of carbonic anhydrase IX in mouse tissues (2004) J Histochem Cyto-chem, 52, pp. 1313-1322
Kyll nen, M. S., Parkkila, S., Rajaniemi, H., Waheed, A., Grubb, J. H., Shah, G. N., Sly, W. S., Kaunisto, K., Localization of carbonic anhydrase XII to the basolateral membrane of H +-secreting cells of mouse and rat kidney (2003) J Histochem Cytochem, 51, pp. 1217-1224
Boriack-Sjodin, P. A., Heck, R. W., Laipis, P. J., Silverman, D. N., Christian-son, D. W., Structure determination of murine mitochondrial carbonic anhydrase V at 2. 45-A resolution: Implications for catalytic proton transfer and inhibitor design (1995) Proc Natl Acad Sci USA, 92, pp. 10949-10953
Kim, C. -Y., Chang, J. S., Doyon, J. B., Baird, T. T., Fierke, C. A., Jain, A., Chris-tianson, D. W., Contribution of fluorine to protein-ligand affinity in the binding of fluoroaromatic inhibitors to carbonic anhydrase II (2000) J Am Chem Soc, 122, pp. 12125-12134
Smith, G. M., Alexander, R. S., Christianson, D. W., McKeever, B. M., Ponti-cello, G. S., Springer, J. P., Randall, W. C., Habecker, C. N., Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors (1994) Protein Sci, 3, pp. 118-125
Whittington, D. A., Waheed, A., Ulmasov, B., Shah, G. N., Grubb, J. H., Sly, W. S., Christianson, D. W., Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells (2001) Proc Natl Acad Sci USA, 98, pp. 9545-9550
Duda, D. M., Tu, C., Fisher, S. Z., An, H., Yoshioka, C., Govindasamy, L., Laipis, P. J., McKenna, R., Human carbonic anhydrase III: Structural and kinetic study of catalysis and proton transfer (2005) Biochemistry, 44, pp. 10046-10053
Eriksson, A. E., Jones, T. A., Liljas, A., Refined structure of human carbonic anhydrase II at 2. 0 resolution (1988) Proteins, 4, pp. 274-282
Kannan, K. K., Ramanadham, M., Jones, T. A., Structure, refinement, and function of carbonic anhydrase isozymes: Refinement of human carbonic anhydrase I (1984) Ann N Y Acad Sci, 429, pp. 49-60
Heck, R. W., Tanhauser, S. M., Manda, R., Tu, C. K., Laipis, P. J., Silverman, D. N., Catalytic properties of mouse carbonic anhydrase V (1994) J Biol Chem, 269, pp. 24742-24746
Khalifah, R. G., Strader, D. J., Bryant, S. H., Gigson, S. M., Carbon-13 nuclear magnetic resonance probe of active-site ionizations in human carbonic anhydrase B (1977) Biochemistry, 16, pp. 2241-2247
Khalifah, R. G., The carbon dioxide hydration activity of carbonic anhydrase (1971) J Biol Chem, 246, pp. 2561-2573
Bruanger, A. T., Adams, P. D., Clore, G. M., De Lano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Warren, G. L., Crystallography & NMR system: A new software suite for macromolecular structure determination (1998) Acta Crystallogr Sect D, 54, pp. 905-921
Jones, T. A., Zou, J. Y., Cowan, S. W., Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models (1991) Acta Crystallogr Sect A, 47, pp. 110-119
Laskowski, R. A., MacArthur, M. W., Moss, D. S., Thornton, J. M., PRO-CHECK: A program to check the stereochemical quality of protein structures (1993) J Appl Crystallogr, 26, pp. 283-291
McGuffin, L. J., Bryson, K., Jones, D. T., The PSIPRED protein structure prediction server (2000) Bioinformatics, 16, pp. 404-405
H kansson, K., Briand, C., Zaitsev, V., Xue, Y., Liljas, A., Wild-type and E106Q mutant carbonic anhydrase complexed with acetate (1994) Acta Crystallogr Sect D, 50, pp. 101-104
H kansson, K., Carlsson, M., Svensson, L. A., Liljas, A., Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes (1992) J Mol Biol, 227, pp. 1192-1204
Maupin, C. M., Voth, G. A., Preferred orientations of His64 in human carbonic anhydrase II (2007) Biochemistry, 46, pp. 2938-2947
Nair, S. K., Christainson, D. W., Unexpected pH-dependent conformation of His64, the Proton Shuttle of Carbonic Anhydrase II (1991) J Am Chem Soc, 113, pp. 9455-9458
Winum, J. -Y., Temperini, C., El Cheikh, K., Innocenti, A., Vullo, D., Ciat-tini, S., Montero, J. -L., Supuran, C. T., Carbonic anhydrase inhibitors: Clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue (2006) J Med Chem, 49, pp. 7024-7031
Huang, C. C., Lesburg, C. A., Kiefer, L. L., Fierke, C. A., Christianson, D. W., Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II (1996) Biochemistry, 35, pp. 3439-3446
Nair, S. K., Krebs, J. F., Christianson, D. W., Fierke, C. A., Structural basis of inhibitor affinity to variants of human carbonic anhydrase II (1995) Biochemistry, 34, pp. 3981-3989
Silverman, D. N., Lindskog, S., The catalytic mechanism of carbonic anhydrase: Implications of a rate-limiting protolysis of water (1988) Acc Chem Res, 21, pp. 30-36
Paranawithana, S. R., Tu, C., Jewell, D. A., Laipis, P. J., Silverman, D. N., Catalytic enhancement of carbonic anhydrase III by introduction of his-tidine 64 as proton shuttle (1991) Carbonic anhydrases from biochemistry and genetics to physiology and clinical medicine, pp. 14-21. , Botre' F, Gros G, Storey BT, editors, Weinheim: Verlag Chemie
Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide