First archaeal PEPB-serine protease inhibitor from sulfolobus solfataricus with noncanonical amino acid sequence in the reactive-site loop(399 views) Palmieri G, Catara G, Saviano M, Langella E, Gogliettino M, Rossi M
J Proteome Res (ISSN: 1535-3893), 2009 Jan; 8(1): 327-334.
Keywords: Homology Modeling, Pebp, Protease Binding Site, Protease Inhibitor Family, Serine Protease Inhibitor, Sulfolobus Solfataricus, Anion, Bacterial Protein, Chymotrypsin A, Elastase, Gene Product, Monomer, Phosphatidylethanolamine Binding Protein, Protein Sscei, Protein Sso0767, Serine Proteinase Inhibitor, Unclassified Drug, Alpha-Chymotrypsin, Amino Acid Sequence, Article, Carboxy Terminal Sequence, Drug Isolation, Drug Structure, Enzyme Active Site, Gene Inactivation, Inhibition Kinetics, Molecular Cloning, Molecular Weight, Nonhuman, Point Mutation, Prediction, Priority Journal, Protein Degradation, Protein Family, Protein Folding, Protein Motif, Protein Structure, Sequence Homology, Surface Property, Archaebacterium, Chemistry, Conformation, Escherichia Coli, Mass Spectrometry, Metabolism, Methodology, Molecular Genetics, Proteomics, Murinae, Catalytic Domain, Molecular Conformation, Molecular Sequence Data, Serine Endopeptidases,
Affiliations: *** IBB - CNR ***
Istituto di Biochimica Delle Proteine, Via P. Castellino 111, 80131 Napoli, Italy
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale delle Ricerche, Via Mezzocannone 16, 80134 Napoli, Italy
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Bruun, A. W., Svendsen, I., Sorensen, S. 0., Kielland-Brandt, M. C., Winther, J. R., A high-affinity inhibitor of yeast carboxypeptidase Y is encoded by TFS1 and shows homology to a family of lipid binding proteins (1998) Biochemistry, 37, pp. 3351-3357
Simister, P. C., Banfield, M. J., Brady, R. L., The crystal structure of PEBP-2, a homologue of the PEBP/RKIP family (2002) Acta Crystallogr., Sect. D, 58, pp. 1077-1080
Chong, P. K., Wright, P. C., Identification and characterization of the Sulfolobus solfataricus P2 proteome (2005) J. Proteome Res, 4, pp. 1789-1798
Le, Q. T., Katunuma, N., Detection of protease inhibitors by a reverse zymography method, performed in a tris (hydroxymethy-l) aminomethane-Tricine buffer system (2004) Anal. Biochem, 324, pp. 237-240
Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., Lipman, D. J., Gapped BLAST and PSI-BLAST: A new generation of protein database search programs (1997) Nucleic Acids Res, 25, pp. 3389-3402
Banfield, M. J., Barker, J. J., Perryand, A. C. F., Brady, R. L., Function from structure? The crystal structure of human phosphatidyl-ethanolamine- binding protein suggests a role in membrane signal transduction (1998) J. Mol. Biol, 6, pp. 1245-1254
Greenblatt, H. M., Ryan, C. A., James, M. N. G., Structure of the complex of Streptomyces griseus proteinase B and polypeptide chymotrypsin inhibitor-1 from Russet Burbank potato tubers at 2. 1k (1989) J. Mol. Biol, 205, pp. 201-228
Song, H. K., Suh, S. W., Kunitz-type soybean trypsin inhibitor revisited: Refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator (1998) J. Mol Biol, 275, pp. 347-363
Dattagupta, J. K., Podder, A., Chakrabarti, C., Sen, U., Mukho-padhyay, D., Dutta, S. K., Singh, M., Refined crystal structure (2. 3 A) of a double-headed winged bean-chymotrypsin inhibitor and location of its second reactive site (1999) Proteins: Struct. Funct. Genet, 54, pp. 321-331
First archaeal PEPB-serine protease inhibitor from sulfolobus solfataricus with noncanonical amino acid sequence in the reactive-site loop