Growth Hormone Deficiency in Patients with Chronic Heart Failure and Beneficial Effects of Its Correction (509 views visite)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2009 Sep; 94(9): 3329-3336.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 6.202, 5-year impact factor Impact factor a 5 anni: 6.46
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-69949126965&partnerID=40&md5=2e07130a437d57f97be4ed102baebb2d
Keywords Parole chiave: Amino Terminal Pro Brain Natriuretic Peptide, Human Growth Hormone, Somatomedin C, Absence Of Side Effects, Adult, Article, Blood Vessel Reactivity, Cardiovascular Effect, Clinical Trial, Controlled Clinical Trial, Controlled Study, Disease Marker, Drug Dose Increase, Drug Dose Reduction, Drug Safety, Exercise, Female, Growth Hormone Deficiency, Heart Ejection Fraction, Heart Failure, Heart Left Ventricle Ejection Fraction, Hormone Substitution, Major Clinical Study, Oxygen Consumption, Physical Performance, Prevalence, Priority Journal, Quality Of Life, Randomized Controlled Trial, Single Blind Procedure, United States, Affect, Aged, Exercise Test, Hormone Replacement Therapy, Insulin-Like Growth Factor I, Middle Aged, Peptide Fragments, Single-Blind Method, Ventricular Function,
Affiliations Affiliazioni:
*** IBB - CNR ***
Department of Internal Medicine and Cardiovascular Sciences, University Federico II, 80131 Naples, Italy
Department of Radiology, University Federico II, 80131 Naples, Italy
Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, 80131 Naples, Italy
References Riferimenti:
Saccà, L., Heart failure as a multiple hormonal deficiency syndrome (2009) Circ Heart Fail, 2, pp. 151-15
Jankowska, E.A., Biel, B., Majda, J., Szklarska, A., Lopuszanska, M., Medras, M., Anker, S.D., Ponikowski, P., Anabolic deficiency in men with chronic heart failure. Prevalence and detrimental impact on survival (2006) Circulation, 114, pp. 1829-1837
Niebauer, J., Pflaum, C.-D., Clark, A.L., Strasburger, C.J., Hooper, J., Poole-Wilson, P.A., Coats, A.J.S., Anker, S.D., Deficient insulin-like growth factor I in chronic heart failure predicts altered body composition, anabolic deficiency, cytokine and neurohormonal activation (1998) Journal of the American College of Cardiology, 32 (2), pp. 393-397. , DOI 10.1016/S0735-1097(98)00226-5, PII S0735109798002265
Rosén, T., Bengtsson, B.A., Premature mortality due to cardiovascular disease in hypopituitarism (1990) Lancet, 336, pp. 285-288
Juul, A., Scheike, T., Davidsen, M., Gyllenborg, J., Jørgensen, T., Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: A population-based case-control study (2002) Circulation, 106, pp. 939-944
Petretta, M., Colao, A., Sardu, C., Scopacasa, F., Marzullo, P., Pivonello, R., Fontanella, L., Bonaduce, D., NT-proBNP, IGF-I and survival in patients with chronic heart failure (2007) Growth Horm IGF Res, 17, pp. 288-296
(2008) Agenzia Italiana del Farmaco Nota 39, , http://www.guidausofarmaci.it/pag9822.htm, (Italian). October 6
Spielberger, C.D., Gorsuch, R.L., Lushene, R.E., (1970) Manual for the State-trait Anxiety Inventory (Self-evaluation Questionnaire), pp. 33-37. , Palo Alto, CA: Consulting Psychologists Press
Zung, W.W.K., A self-rating depression scale (1965) Arch Gen Psychiatry, 12, pp. 63-70
ATS/ACCP 2001 statement on cardiopulmonary exercise testing (2003) Am J Resp Crit Care Med, 167, pp. 221-277. , American Thoracic Society
Corretti, M.C., Anderson, T.J., Benjamin, E.J., Celermajer, D., Charbonneau, F., Creager, M.A., Deanfield, J., Vogel, R., Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: A report of the international brachial artery reactivity task force (2002) Journal of the American College of Cardiology, 39 (2), pp. 257-265. , DOI 10.1016/S0735-1097(01)01746-6, PII S0735109701017466
Sandstede, J., Lipke, C., Beer, M., Hofmann, S., Pabst, T., Kenn, W., Neubauer, S., Hahn, D., Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging (2000) European Radiology, 10 (3), pp. 438-442
Broglio, F., Fubinl, A., Morello, M., Arvat, E., Aimaretti, G., Gianotti, L., Boghen, M.F., Ghigo, E., Activity of GH/IGF-I axis in patients with dilated cardiomyopathy (1999) Clinical Endocrinology, 50 (4), pp. 417-430. , DOI 10.1046/j.1365-2265.1999.00696.x
Broglio, F., Benso, A., Gottero, C., Di Vito, L., Aimaretti, G., Fubini, A., Arvat, E., Ghigo, E., Patients with dilated cardiomyopathy show reduction of the somatotroph responsiveness to GHRH both alone and combined with arginine (2000) European Journal of Endocrinology, 142 (2), pp. 157-163
Anwar, A., Gaspoz, J.-M., Pampallona, S., Zahid, A.A., Sigaud, P., Pichard, C., Brink, M., Delafontaine, P., Effect of congestive heart failure on the insulin-like growth factor-1 system (2002) American Journal of Cardiology, 90 (12), pp. 1402-1405. , DOI 10.1016/S0002-9149(02)02885-0, PII S0002914902028850
Kontoleon, P.E., Anastasiou-Nana, M.I., Papapetrou, P.D., Alexopoulos, G., Ktenas, V., Rapti, A.C., Tsagalou, E.P., Nanas, J.N., Hormonal profile in patients with congestive heart failure (2003) International Journal of Cardiology, 87 (2-3), pp. 179-183. , DOI 10.1016/S0167-5273(02)00212-7, PII S0167527302002127
Anker, S.D., Volterrani, M., Pflaum, C.-D., Strasburger, C.J., Osterziel, K.J., Doehner, W., Ranke, M.B., Coats, A.J.S., Acquired growth hormone resistance in patients with chronic heart failure: Implications for therapy with growth hormone (2001) Journal of the American College of Cardiology, 38 (2), pp. 443-452. , DOI 10.1016/S0735-1097(01)01385-7, PII S0735109701013857
Corneli, G., Di Somma, C., Baldelli, R., Rovere, S., Gasco, V., Croce, C.G., Grottoli, S., Aimaretti, G., The cut-off limits of the GH response to GH-releasing hormone-arginine test related to body mass index (2005) European Journal of Endocrinology, 153 (2), pp. 257-264. , DOI 10.1530/eje.1.01967
Mann, D.L., Bristow, M.R., Mechanisms and models in heart failure. The biochemical model and beyond (2005) Circulation, 111, pp. 2837-2849
Morgan, K., McGee, H., Shelley, E., Quality of life assessment in heart failure interventions: A 10-year (1996-2005) review (2007) European Journal of Cardiovascular Prevention and Rehabilitation, 14 (5), pp. 589-607. , DOI 10.1097/HJR.0b013e32828622c3, PII 0014983120071000000002
Mahajan, T., Crown, A., Checkley, S., Farmer, A., Lightman, S., Atypical depression in growth hormone deficient adults, and the beneficial effects of growth hormone treatment on depression and quality of life (2004) European Journal of Endocrinology, 151 (3), pp. 325-332. , DOI 10.1530/eje.0.1510325
Johansson, J.O., Larson, G., Andersson, M., Elmgren, A., Hynsjö, L., Lindahl, A., Lundberg, P.A., Bengtsson, B.A., Treatment of growth hormone deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluidandaffects neurotransmitters (1995) Neuroendocrinology, 61, pp. 57-66
Fazio, S., Sabatini, D., Capaldo, B., Vigorito, C., Giordano, A., Guida, R., Pardo, F., Saccà, L., A preliminary study of growth hormone in the treatment of dilated cardiomyopathy (1996) NEngl J Med, 334, pp. 809-814
Fazio, S., Palmieri, E.A., Affuso, F., Cittadini, A., Castellano, G., Russo, T., Ruvolo, A., Saccà, L., Effects of growth hormone on exercise capacity and cardiopulmonary performance in patients with chronic heart failure (2007) J Clin Endocrinol Metab, 92, pp. 4218-4223
Genth-Zotz, S., Zotz, R., Geil, S., Voigtlander, T., Meyer, J., Darius, H., Recombinant growth hormone therapy in patients with ischemic cardiomyopathy: Effects on hemodynamics, left ventricular function, and cardiopulmonary exercise capacity (1999) Circulation, 99 (1), pp. 18-21
Napoli, R., Guardasole, V., Matarazzo, M., Palmieri, E.A., Oliviero, U., Fazio, S., Saccà, L., Growth hormone corrects vascular dysfunction in patients with chronic heart failure (2002) J Am Coll Cardiol, 39, pp. 90-95
Cittadini, A., Stromer, H., Katz, S.E., Clark, R., Moses, A.C., Morgan, J.P., Douglas, P.S., Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation (1996) Circulation, 93 (4), pp. 800-809
Bruel, A., Oxlund, H., The effect of growth hormone on rat myocardial collagen (1999) Growth Hormone and IGF Research, 9 (2), pp. 123-130. , DOI 10.1054/ghir.1999.0097
Suleiman, M.-S., Singh, R.J.R., Stewart, C.E.H., Apoptosis and the cardiac action of insulin-like growth factor I (2007) Pharmacology and Therapeutics, 114 (3), pp. 278-294. , DOI 10.1016/j.pharmthera.2007.03.001, PII S0163725807000496
Amato, G., Carella, C., Fazio, S., La Montagna, G., Cittadini, A., Sabatini, D., Marciano-Mone, C., Bellastella, A., Body composition, bone metabolism, and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses (1993) Journal of Clinical Endocrinology and Metabolism, 77 (6), pp. 1671-1676. , DOI 10.1210/jc.77.6.1671
Duerr, R.L., Huang, S., Miraliakbar, H.R., Clark, R., Chien, K.R., Ross Jr., J., Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental heart failure (1995) J Clin Invest, 95, pp. 619-627
Li, Q., Li, B., Wang, X., Leri, A., Jana, K.P., Liu, Y., Kajstura, J., Anversa, P., Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy (1997) Journal of Clinical Investigation, 100 (8), pp. 1991-1999
Kusano, K., Tsutsumi, Y., Dean, J., Gavin, M., Ma, H., Silver, M., Thorne, T., Aikawa, R., Long-term stable expression of human growth hormone by rAAV promotes myocardial protection post-myocardial infarction (2007) Journal of Molecular and Cellular Cardiology, 42 (2), pp. 390-399. , DOI 10.1016/j.yjmcc.2006.10.016, PII S0022282806009825
Adamopoulos, S., Parissis, J.T., Paraskevaidis, I., Karatzas, D., Livanis, E., Georgiadis, M., Karavolias, G., Kremastinos, D.T., Effects of growth hormone on circulating cytokine network, and left ventricular contractile performance and geometry in patients with idiopathic dilated cardiomyopathy (2003) European Heart Journal, 24 (24), pp. 2186-2196. , DOI 10.1016/S0195-668X(03)00480-9
Osterziel, K.J., Strohm, O., Schuler, J., Friedrich, M., Hanlein, D., Willenbrock, R., Anker, S.D., Dietz, R., Randomised, double-blind, placebo-controlled trial of human recombinant growth hormone in patients with chronic heart failure due to dilated cardiomyopathy (1998) Lancet, 351 (9111), pp. 1233-1237. , DOI 10.1016/S0140-6736(97)11329-0
Perrot, A., Ranke, M.B., Dietz, R., Osterziel, K.J., Growth hormone treatment in dilated cardiomyopathy (2001) Journal of Cardiac Surgery, 16 (2), pp. 127-131
Le Corvoisier, P., Hittinger, L., Chanson, P., Montagne, O., Macquin-Mavier, I., Maison, P., Cardiac effects of growth hormone treatment in chronic heart failure: A meta-analysis (2007) Journal of Clinical Endocrinology and Metabolism, 92 (1), pp. 180-185. , http://jcem.endojournals.org/cgi/reprint/92/1/180, DOI 10.1210/jc.2006-1313
Ho, K.K., GH Deficiency Consensus Workshop participants 2007 Consensus guidelines for the diagnosis and treatment of adults with GH deficiency II: A statement of the GH Research Society in association with the European Society for Pediatric Endocrinology, Lawson Wilkins Society, European Society of Endocrinology, Japan Endocrine Society, and Endocrine Society of Australia (2007) Eur J Endocrinol, 157, pp. 695-700
Friedrich, N., Alte, D., Völzke, H., Spilcke-Liss, E., Lüdemann, J., Lerch, M.M., Kohlmann, T., Wallaschofski, H., Reference ranges of serum IGF-I and IGFBP-3 levels in a general adult population: Results of the Study of Health in Pomerania (SHIP) (2008) Growth Horm IGF Res, 18, pp. 228-237
Aimaretti, G., Boschetti, M., Corneli, G., Gasco, V., Valle, D., Borsotti, M., Rossi, A., Minuto, F., Normal age-dependent values of serum insulin growth factor-I: Results from a healthy Italian population (2008) Journal of Endocrinological Investigation, 31 (5), pp. 445-449
Sacc, L., Heart failure as a multiple hormonal deficiency syndrome (2009) Circ Heart Fail, 2, pp. 151-15
Jankowska, E. A., Biel, B., Majda, J., Szklarska, A., Lopuszanska, M., Medras, M., Anker, S. D., Ponikowski, P., Anabolic deficiency in men with chronic heart failure. Prevalence and detrimental impact on survival (2006) Circulation, 114, pp. 1829-1837
Ros n, T., Bengtsson, B. A., Premature mortality due to cardiovascular disease in hypopituitarism (1990) Lancet, 336, pp. 285-288
(2008) Agenzia Italiana del Farmaco Nota 39, , http: //www. guidausofarmaci. it/pag9822. htm, (Italian). October 6
Spielberger, C. D., Gorsuch, R. L., Lushene, R. E., (1970) Manual for the State-trait Anxiety Inventory (Self-evaluation Questionnaire), pp. 33-37. , Palo Alto, CA: Consulting Psychologists Press
Zung, W. W. K., A self-rating depression scale (1965) Arch Gen Psychiatry, 12, pp. 63-70
Corretti, M. C., Anderson, T. J., Benjamin, E. J., Celermajer, D., Charbonneau, F., Creager, M. A., Deanfield, J., Vogel, R., Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: A report of the international brachial artery reactivity task force (2002) Journal of the American College of Cardiology, 39 (2), pp. 257-265. , DOI 10. 1016/S0735-1097 (01) 01746-6, PII S0735109701017466
Kontoleon, P. E., Anastasiou-Nana, M. I., Papapetrou, P. D., Alexopoulos, G., Ktenas, V., Rapti, A. C., Tsagalou, E. P., Nanas, J. N., Hormonal profile in patients with congestive heart failure (2003) International Journal of Cardiology, 87 (2-3), pp. 179-183. , DOI 10. 1016/S0167-5273 (02) 00212-7, PII S0167527302002127
Anker, S. D., Volterrani, M., Pflaum, C. -D., Strasburger, C. J., Osterziel, K. J., Doehner, W., Ranke, M. B., Coats, A. J. S., Acquired growth hormone resistance in patients with chronic heart failure: Implications for therapy with growth hormone (2001) Journal of the American College of Cardiology, 38 (2), pp. 443-452. , DOI 10. 1016/S0735-1097 (01) 01385-7, PII S0735109701013857
Mann, D. L., Bristow, M. R., Mechanisms and models in heart failure. The biochemical model and beyond (2005) Circulation, 111, pp. 2837-2849
Johansson, J. O., Larson, G., Andersson, M., Elmgren, A., Hynsj, L., Lindahl, A., Lundberg, P. A., Bengtsson, B. A., Treatment of growth hormone deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluidandaffects neurotransmitters (1995) Neuroendocrinology, 61, pp. 57-66
Suleiman, M. -S., Singh, R. J. R., Stewart, C. E. H., Apoptosis and the cardiac action of insulin-like growth factor I (2007) Pharmacology and Therapeutics, 114 (3), pp. 278-294. , DOI 10. 1016/j. pharmthera. 2007. 03. 001, PII S0163725807000496
Duerr, R. L., Huang, S., Miraliakbar, H. R., Clark, R., Chien, K. R., Ross Jr., J., Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental heart failure (1995) J Clin Invest, 95, pp. 619-627
Osterziel, K. J., Strohm, O., Schuler, J., Friedrich, M., Hanlein, D., Willenbrock, R., Anker, S. D., Dietz, R., Randomised, double-blind, placebo-controlled trial of human recombinant growth hormone in patients with chronic heart failure due to dilated cardiomyopathy (1998) Lancet, 351 (9111), pp. 1233-1237. , DOI 10. 1016/S0140-6736 (97) 11329-0
Ho, K. K., GH Deficiency Consensus Workshop participants 2007 Consensus guidelines for the diagnosis and treatment of adults with GH deficiency II: A statement of the GH Research Society in association with the European Society for Pediatric Endocrinology, Lawson Wilkins Society, European Society of Endocrinology, Japan Endocrine Society, and Endocrine Society of Australia (2007) Eur J Endocrinol, 157, pp. 695-700
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2009 Sep; 94(9): 3329-3336.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 6.202, 5-year impact factor Impact factor a 5 anni: 6.46
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-69949126965&partnerID=40&md5=2e07130a437d57f97be4ed102baebb2d
Keywords Parole chiave: Amino Terminal Pro Brain Natriuretic Peptide, Human Growth Hormone, Somatomedin C, Absence Of Side Effects, Adult, Article, Blood Vessel Reactivity, Cardiovascular Effect, Clinical Trial, Controlled Clinical Trial, Controlled Study, Disease Marker, Drug Dose Increase, Drug Dose Reduction, Drug Safety, Exercise, Female, Growth Hormone Deficiency, Heart Ejection Fraction, Heart Failure, Heart Left Ventricle Ejection Fraction, Hormone Substitution, Major Clinical Study, Oxygen Consumption, Physical Performance, Prevalence, Priority Journal, Quality Of Life, Randomized Controlled Trial, Single Blind Procedure, United States, Affect, Aged, Exercise Test, Hormone Replacement Therapy, Insulin-Like Growth Factor I, Middle Aged, Peptide Fragments, Single-Blind Method, Ventricular Function,
Affiliations Affiliazioni:
*** IBB - CNR ***
Department of Internal Medicine and Cardiovascular Sciences, University Federico II, 80131 Naples, Italy
Department of Radiology, University Federico II, 80131 Naples, Italy
Department of Molecular and Clinical Endocrinology and Oncology, University Federico II, 80131 Naples, Italy
References Riferimenti:
Saccà, L., Heart failure as a multiple hormonal deficiency syndrome (2009) Circ Heart Fail, 2, pp. 151-15
Jankowska, E.A., Biel, B., Majda, J., Szklarska, A., Lopuszanska, M., Medras, M., Anker, S.D., Ponikowski, P., Anabolic deficiency in men with chronic heart failure. Prevalence and detrimental impact on survival (2006) Circulation, 114, pp. 1829-1837
Niebauer, J., Pflaum, C.-D., Clark, A.L., Strasburger, C.J., Hooper, J., Poole-Wilson, P.A., Coats, A.J.S., Anker, S.D., Deficient insulin-like growth factor I in chronic heart failure predicts altered body composition, anabolic deficiency, cytokine and neurohormonal activation (1998) Journal of the American College of Cardiology, 32 (2), pp. 393-397. , DOI 10.1016/S0735-1097(98)00226-5, PII S0735109798002265
Rosén, T., Bengtsson, B.A., Premature mortality due to cardiovascular disease in hypopituitarism (1990) Lancet, 336, pp. 285-288
Juul, A., Scheike, T., Davidsen, M., Gyllenborg, J., Jørgensen, T., Low serum insulin-like growth factor I is associated with increased risk of ischemic heart disease: A population-based case-control study (2002) Circulation, 106, pp. 939-944
Petretta, M., Colao, A., Sardu, C., Scopacasa, F., Marzullo, P., Pivonello, R., Fontanella, L., Bonaduce, D., NT-proBNP, IGF-I and survival in patients with chronic heart failure (2007) Growth Horm IGF Res, 17, pp. 288-296
(2008) Agenzia Italiana del Farmaco Nota 39, , http://www.guidausofarmaci.it/pag9822.htm, (Italian). October 6
Spielberger, C.D., Gorsuch, R.L., Lushene, R.E., (1970) Manual for the State-trait Anxiety Inventory (Self-evaluation Questionnaire), pp. 33-37. , Palo Alto, CA: Consulting Psychologists Press
Zung, W.W.K., A self-rating depression scale (1965) Arch Gen Psychiatry, 12, pp. 63-70
ATS/ACCP 2001 statement on cardiopulmonary exercise testing (2003) Am J Resp Crit Care Med, 167, pp. 221-277. , American Thoracic Society
Corretti, M.C., Anderson, T.J., Benjamin, E.J., Celermajer, D., Charbonneau, F., Creager, M.A., Deanfield, J., Vogel, R., Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: A report of the international brachial artery reactivity task force (2002) Journal of the American College of Cardiology, 39 (2), pp. 257-265. , DOI 10.1016/S0735-1097(01)01746-6, PII S0735109701017466
Sandstede, J., Lipke, C., Beer, M., Hofmann, S., Pabst, T., Kenn, W., Neubauer, S., Hahn, D., Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging (2000) European Radiology, 10 (3), pp. 438-442
Broglio, F., Fubinl, A., Morello, M., Arvat, E., Aimaretti, G., Gianotti, L., Boghen, M.F., Ghigo, E., Activity of GH/IGF-I axis in patients with dilated cardiomyopathy (1999) Clinical Endocrinology, 50 (4), pp. 417-430. , DOI 10.1046/j.1365-2265.1999.00696.x
Broglio, F., Benso, A., Gottero, C., Di Vito, L., Aimaretti, G., Fubini, A., Arvat, E., Ghigo, E., Patients with dilated cardiomyopathy show reduction of the somatotroph responsiveness to GHRH both alone and combined with arginine (2000) European Journal of Endocrinology, 142 (2), pp. 157-163
Anwar, A., Gaspoz, J.-M., Pampallona, S., Zahid, A.A., Sigaud, P., Pichard, C., Brink, M., Delafontaine, P., Effect of congestive heart failure on the insulin-like growth factor-1 system (2002) American Journal of Cardiology, 90 (12), pp. 1402-1405. , DOI 10.1016/S0002-9149(02)02885-0, PII S0002914902028850
Kontoleon, P.E., Anastasiou-Nana, M.I., Papapetrou, P.D., Alexopoulos, G., Ktenas, V., Rapti, A.C., Tsagalou, E.P., Nanas, J.N., Hormonal profile in patients with congestive heart failure (2003) International Journal of Cardiology, 87 (2-3), pp. 179-183. , DOI 10.1016/S0167-5273(02)00212-7, PII S0167527302002127
Anker, S.D., Volterrani, M., Pflaum, C.-D., Strasburger, C.J., Osterziel, K.J., Doehner, W., Ranke, M.B., Coats, A.J.S., Acquired growth hormone resistance in patients with chronic heart failure: Implications for therapy with growth hormone (2001) Journal of the American College of Cardiology, 38 (2), pp. 443-452. , DOI 10.1016/S0735-1097(01)01385-7, PII S0735109701013857
Corneli, G., Di Somma, C., Baldelli, R., Rovere, S., Gasco, V., Croce, C.G., Grottoli, S., Aimaretti, G., The cut-off limits of the GH response to GH-releasing hormone-arginine test related to body mass index (2005) European Journal of Endocrinology, 153 (2), pp. 257-264. , DOI 10.1530/eje.1.01967
Mann, D.L., Bristow, M.R., Mechanisms and models in heart failure. The biochemical model and beyond (2005) Circulation, 111, pp. 2837-2849
Morgan, K., McGee, H., Shelley, E., Quality of life assessment in heart failure interventions: A 10-year (1996-2005) review (2007) European Journal of Cardiovascular Prevention and Rehabilitation, 14 (5), pp. 589-607. , DOI 10.1097/HJR.0b013e32828622c3, PII 0014983120071000000002
Mahajan, T., Crown, A., Checkley, S., Farmer, A., Lightman, S., Atypical depression in growth hormone deficient adults, and the beneficial effects of growth hormone treatment on depression and quality of life (2004) European Journal of Endocrinology, 151 (3), pp. 325-332. , DOI 10.1530/eje.0.1510325
Johansson, J.O., Larson, G., Andersson, M., Elmgren, A., Hynsjö, L., Lindahl, A., Lundberg, P.A., Bengtsson, B.A., Treatment of growth hormone deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluidandaffects neurotransmitters (1995) Neuroendocrinology, 61, pp. 57-66
Fazio, S., Sabatini, D., Capaldo, B., Vigorito, C., Giordano, A., Guida, R., Pardo, F., Saccà, L., A preliminary study of growth hormone in the treatment of dilated cardiomyopathy (1996) NEngl J Med, 334, pp. 809-814
Fazio, S., Palmieri, E.A., Affuso, F., Cittadini, A., Castellano, G., Russo, T., Ruvolo, A., Saccà, L., Effects of growth hormone on exercise capacity and cardiopulmonary performance in patients with chronic heart failure (2007) J Clin Endocrinol Metab, 92, pp. 4218-4223
Genth-Zotz, S., Zotz, R., Geil, S., Voigtlander, T., Meyer, J., Darius, H., Recombinant growth hormone therapy in patients with ischemic cardiomyopathy: Effects on hemodynamics, left ventricular function, and cardiopulmonary exercise capacity (1999) Circulation, 99 (1), pp. 18-21
Napoli, R., Guardasole, V., Matarazzo, M., Palmieri, E.A., Oliviero, U., Fazio, S., Saccà, L., Growth hormone corrects vascular dysfunction in patients with chronic heart failure (2002) J Am Coll Cardiol, 39, pp. 90-95
Cittadini, A., Stromer, H., Katz, S.E., Clark, R., Moses, A.C., Morgan, J.P., Douglas, P.S., Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation (1996) Circulation, 93 (4), pp. 800-809
Bruel, A., Oxlund, H., The effect of growth hormone on rat myocardial collagen (1999) Growth Hormone and IGF Research, 9 (2), pp. 123-130. , DOI 10.1054/ghir.1999.0097
Suleiman, M.-S., Singh, R.J.R., Stewart, C.E.H., Apoptosis and the cardiac action of insulin-like growth factor I (2007) Pharmacology and Therapeutics, 114 (3), pp. 278-294. , DOI 10.1016/j.pharmthera.2007.03.001, PII S0163725807000496
Amato, G., Carella, C., Fazio, S., La Montagna, G., Cittadini, A., Sabatini, D., Marciano-Mone, C., Bellastella, A., Body composition, bone metabolism, and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses (1993) Journal of Clinical Endocrinology and Metabolism, 77 (6), pp. 1671-1676. , DOI 10.1210/jc.77.6.1671
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Growth Hormone Deficiency in Patients with Chronic Heart Failure and Beneficial Effects of Its Correction
Context: A reduced activity of the GH/IGF-I axis in chronic heart failure (CHF) has been described by several independent groups and is associated with poor clinical status and outcome. Objective: The aim of the current study was to investigate the prevalence of GH deficiency in a patient population with CHF and evaluate the cardiovascular effects of GH replacement therapy. Design and Setting: The randomized, single-blind, controlled trial was conducted at the Federico II University. Participants: One hundred fifty-eight patients with CHF, New York Heart Association class II-IV, underwent a GH stimulation test. Sixty-three patients satisfied the criteria for GH deficiency, and 56 of them were enrolled in the trial. Intervention: The treated group (n = 28) received GH at a replacement dose of 0.012 mg/kg every second day (similar to 2.5 IU). Main Outcomes Measures: Changes in physical performance and various cardiovascular indexes were measured. Results: GH replacement therapy improved quality of life score (from 46 +/- 5 to 38 +/- 4; P < 0.01), increased peak oxygen uptake and exercise duration (from 12.9 +/-. 9 to 14.5 +/- 1 ml/kg . min and from 520 +/- 36 to 586 +/- 43 sec, respectively; P < 0.01), and flow-mediated vasodilation (from 8.8 +/- 1.3 to 12.7 +/- 1.2%; P < 0.01). GH increased left ventricular ejection fraction (from 34 +/- 2to36 +/- 2%; P < 0.01) and reduced circulating N-terminal pro-brain natriuretic peptide levels (from 3201 +/- 900 to 2177 +/- 720 pg/ml; P = 0.006). No significant changes from baseline were observed in controls. Conclusions: As many as 40% of patients with CHF are GH deficient. GH replacement therapy in these patients improves exercise capacity, vascular reactivity, left ventricular function, and indices of quality of life. (J Clin Endocrinol Metab 94: 3329-3336, 2009)
Context: A reduced activity of the GH/IGF-I axis in chronic heart failure (CHF) has been described by several independent groups and is associated with poor clinical status and outcome. Objective: The aim of the current study was to investigate the prevalence of GH deficiency in a patient population with CHF and evaluate the cardiovascular effects of GH replacement therapy. Design and Setting: The randomized, single-blind, controlled trial was conducted at the Federico II University. Participants: One hundred fifty-eight patients with CHF, New York Heart Association class II-IV, underwent a GH stimulation test. Sixty-three patients satisfied the criteria for GH deficiency, and 56 of them were enrolled in the trial. Intervention: The treated group (n = 28) received GH at a replacement dose of 0.012 mg/kg every second day (similar to 2.5 IU). Main Outcomes Measures: Changes in physical performance and various cardiovascular indexes were measured. Results: GH replacement therapy improved quality of life score (from 46 +/- 5 to 38 +/- 4; P < 0.01), increased peak oxygen uptake and exercise duration (from 12.9 +/-. 9 to 14.5 +/- 1 ml/kg . min and from 520 +/- 36 to 586 +/- 43 sec, respectively; P < 0.01), and flow-mediated vasodilation (from 8.8 +/- 1.3 to 12.7 +/- 1.2%; P < 0.01). GH increased left ventricular ejection fraction (from 34 +/- 2to36 +/- 2%; P < 0.01) and reduced circulating N-terminal pro-brain natriuretic peptide levels (from 3201 +/- 900 to 2177 +/- 720 pg/ml; P = 0.006). No significant changes from baseline were observed in controls. Conclusions: As many as 40% of patients with CHF are GH deficient. GH replacement therapy in these patients improves exercise capacity, vascular reactivity, left ventricular function, and indices of quality of life. (J Clin Endocrinol Metab 94: 3329-3336, 2009)
Growth Hormone Deficiency in Patients with Chronic Heart Failure and Beneficial Effects of Its Correction
No results. Nessun risultato. |
Growth Hormone Deficiency in Patients with Chronic Heart Failure and Beneficial Effects of Its Correction
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Lanzillo R, Di Somma C, Quarantelli M, Carotenuto A, Pivonello C, Moccia M, Cianflone A, Marsili A, Puorro G, Sacca F, Russo CV, De Luca Picione C, Ausiello F, Colao A, Brescia Morra V
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Impact Factor: 4.621
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Giuffrida ML, Tomasello MF, Pandini G, Caraci F, Battaglia G, Busceti C, Di Pietro P, Pappalardo G, Attanasio F, Chiechio S, Bagnoli S, Nacmias B, Sorbi S, Vigneri R, Rizzarelli E, Nicoletti F, Copani A
* Monomeric ss-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons (471 visite)
Front Cell Neurosci (ISSN: 1662-5102), 2015 Aug 7; 9(AUGUST): 297-297.
Impact Factor: 4.609
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Milardi D, Sciacca MF, Randazzo L, Raudino A, La Rosa C
* The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime? (396 visite)
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Impact Factor: 3.675
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Dynkevich Y, Rother KI, Whitford I, Qureshi S, Galiveeti S, Szulc AL, Danoff A, Breen TL, Kaviani N, Shanik MH, LeRoith D, Vigneri R, Koch CA, Roth J
* Tumors, IGF-2, and Hypoglycemia: Insights From the Clinic, the Laboratory, and the Historical Archive (1317 visite)
Endocrine Reviews (ISSN: 0163-769x), 2013 Dec; 34(6): 798-826.
Impact Factor: 19.358
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Ciccarelli M, Sorriento D, Franco A, Fusco A, Del Giudice C, Annunziata R, Cipolletta E, Monti MG, Dorn GW, Trimarco B, Iaccarino G
* Endothelial G protein-coupled receptor kinase 2 regulates vascular homeostasis through the control of free radical oxygen species (359 visite)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 2013; 33(10): 2415-2424.
Impact Factor: 5.533
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Giuffrida ML, Tomasello F, Caraci F, Chiechio S, Nicoletti F, Copani A
* Beta-Amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease (545 visite)
Mol Neurobiol (ISSN: 0893-7648), 2012 Dec; 46(3): 605-613.
Impact Factor: 5.471
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Saccà F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Perrotta G, Carotenuto B, Marsili A, Palma V, De Michele G, Brunetti A, Brescia Morra V, Filla A, Salvatore M
* A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results (625 visite)
J Neurol (ISSN: 1432-1459, 0340-5354, 1432-1459electronic), 2012 Jan; 259(1): 132-138.
Impact Factor: 3.578
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (539 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Giuffrida ML, Caraci F, Pignataro B, Cataldo S, De Bona P, Bruno V, Molinaro G, Pappalardo G, Messina A, Palmigiano A, Garozzo D, Nicoletti F, Rizzarelli E, Copani A
* Beta-Amyloid Monomers Are Neuroprotective (544 visite)
J Neurosci (ISSN: 1529-2401, 0270-6474), 2009 Sep 26; 29(34): 10582-10587.
Impact Factor: 3.669
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Cittadini A, Monti MG, Castiello MC, D'Arco E, Galasso G, Sorriento D, Saldamarco L, De Paulis A, Napoli R, Iaccarino G, Saccà L
* Insulin-like growth factor-1 protects from vascular stenosis and accelerates re-endothelialization in a rat model of carotid artery injury (361 visite)
J Thromb Haemost Journal Of Thrombosis And Haemostasis (ISSN: 1538-7933), 2009; 7(11): 1920-1928.
Impact Factor: 6.069
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Migliore T, Parrella LS, Caputi A, Silvestri N, Romano R, Pace L, Imbriaco M, Losi MA, Betocchi S
* Pathogenesis of hypertrophic cardiomyopathy. Impact of growth factors on left ventricular anatomy (338 visite)
Minerva Cardioangiol (ISSN: 0026-4725), 2008 Feb; 56(1): 13-20.
Impact Factor: 0.481
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Frasca F, Pandini G, Sciacca L, Pezzino V, Squatrito S, Belfiore A, Vigneri R
* The role of insulin receptors and IGF-I receptors in cancer and other diseases (1521 visite)
Archives Of Physiology And Biochemistry (ISSN: 1381-3455), 2008 Feb; 114(1): 23-37.
Impact Factor: 2.028
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (399 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Colao A, Di Somma C, Cuocolo A, Filippella M, Rota F, Acampa W, Savastano S, Salvatore M, Lombardi G
* The severity of growth hormone deficiency correlates with the severity of cardiac impairment in 100 adult patients with hypopituitarism: An observational, case-control study (270 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2004 Dec; 89(12): 5998-6004.
Impact Factor: 5.778
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Spinelli L, Petretta M, Verderame G, Carbone G, Venetucci AA, Petretta A, Acampa W, Bonaduce D, Colao A, Cuocolo A
* Left ventricular diastolic function and cardiac performance during exercise in patients with acromegaly (361 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2003 Sep; 88(9): 4105-4109.
Impact Factor: 5.873
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Colao A, Marzullo P, Cuocolo A, Spinelli L, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide (392 visite)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Feb; 58(2): 169-176.
Impact Factor: 2.767
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Leosco D, Iaccarino G, Cipolletta E, De Santis D, Pisani E, Trimarco V, Ferrara N, Abete P, Sorriento D, Rengo F, Trimarco B
* Exercise restores β-adrenergic vasorelaxation in aged rat carotid arteries (305 visite)
Am J Physiol Heart Circ Physiol American Journal Of Physiology Heart And Circulatory Physiology (ISSN: 0363-6135), 2003; 285(154-1): H369-H369.
Impact Factor: 3.658
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Spinelli L, Cuocolo A, Spiezia S, Pivonello R, Di Somma C, Bonaduce D, Salvatore M, Lombardi G
* Cardiovascular consequences of early-onset growth hormone excess (341 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Jul; 87(7): 3097-3104.
Impact Factor: 5.199
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (334 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (301 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Morte A, Pivonello R, Salvatore M, Lombardi G
* Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance (269 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 Apr; 86(4): 1551-1557.
Impact Factor: 5.16
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Marzullo P, Ferone D, Spinelli L, Cuocolo A, Bonaduce D, Salvatore M, Boerlin V, Lancranjan I, Lombardi G
Cardiovascular effects of depot long-acting somatostatin analog sandostatin LAR in acromegaly (338 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Sep; 85(9): 3132-3140.
Impact Factor: 5.447
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Marzullo P, Cuocolo A, Ferone D, Pivonello R, Salvatore M, Lombardi G, Colao A
Cardiac effect of thyrotoxicosis in acromegaly (356 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Apr; 85(4): 1426-1432.
Impact Factor: 5.447
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (264 visite)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Nicolai E, Lucci R, Salvatore M, Lombardi G
Impaired cardiac performance in elderly patients with growth hormone deficiency (285 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Nov; 84(11): 3950-3955.
Impact Factor: 5.805
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Della Morte A, Petretta M, Salvatore M, Lombardi G
Impact of patient's age and disease duration on cardiac performance in acromegaly: A radionuclide angiography study (251 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 May; 84(5): 1518-1523.
Impact Factor: 5.805
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (358 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
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Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Florimonte L, Salvatore M, Lombardi G
Effects of 1-year treatment with octreotide on cardiac performance in patients with acromegaly (292 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Jan; 84(1): 17-23.
Impact Factor: 5.805
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Ferone D, Lastoria S, Colao A, Varrella P, Cerbone G, Acampa W, Merola B, Salvatore M, Lombardi G
Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas (287 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1998 Jan; 83(1): 248-252.
Impact Factor: 5.641
Dettagli Esporta in BibTeX Esporta in EndNote
Lombardi G, Colao A, Cuocolo A, Longobardi S, Di Somma C, Orio F, Merola B, Nicolai E, Salvatore M
Cardiological aspects of growth hormone and insulin-like growth factor- (311 visite)
J Pediatr Endocrinol Metab (ISSN: 0334-018x), 1997 Nov; 10(6): 553-560.
Impact Factor: 0.481
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Pezzino V, Papa V, Trischitta V, Brunetti A, Goodman PA, Treutelaar MK, Williams JA, Maddux BA, Vigneri R, Goldfine ID
Human insulin receptor radioimmunoassay: Applicability to insulin-resistant states (237 visite)
Am J Physiol Endocrinol Metab (ISSN: 0002-9513), 1989 Sep; 257(3): N/D-N/D.
Impact Factor: 3.116
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Mancini M, De Chiara S, Ferrara LA, Gallotta G, Postiglione A
TRANSCRANIAL DOPPLER EVALUATION OF CEREBROVASCULAR REACTIVITY TO ACETAZOLAMIDE IN NORMAL SUBJECTS (617 visite)
15th World Congress Angiology Rome, 1989; 20(4): 284-284.
Impact Factor: 0
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32 Records (29 escludendo Abstract e Conferenze).
Impact factor totale: 150.66 (143.869 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 115.47 (115.47 escludendo Abstract e Conferenze).
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