Department of Biological Sciences, Division of Biostructures and Centro Interuniversitario di Ricerca sui Peptidi Bioattivi - University of Naples Federico II, and Istituto di Biostrutture e Bioimmagini - CNR, Via Mezzocannone 16, Napoli 80134, Italy.
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Kemble, G. W., Danieli, T., White, J. M., Lipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion (1994) Cell, 76 (2), pp. 383-391. , DOI 10. 1016/0092-8674 (94) 90344-1
Melikyan, G. B., Markosyan, R. M., Hemmati, H., Delmedico, M. K., Lambert, D. M., Cohen, F. S., Evidence that the transition of HIV-1 gp41 into a sixhelix bundle, not the bundle configuration, induces membrane fusion (2000) J. Cell Biol., 151 (2), pp. 413-423
Russell, C. J., Jardetzky, T. S., Lamb, R. A., Membrane fusion machines of paramyxoviruses: Capture of intermediates of fusion (2001) EMBO J., 20 (15), pp. 4024-4034
Rothman, J. E., Mechanism of intracellular protein transport (1994) Nature, 372 (6501), pp. 55-63
Kuehn, M. J., Schekman, R., COPII and secretory cargo capture into transport vesicles (1997) Curr. Opin. Cell Biol., 9 (4), pp. 477-483
Mettenleiter, T. C., Klupp, B. G., Granzow, H., Herpesvirus assembly: A tale of two membranes (2006) Curr. Opin. Microbiol., 9 (4), pp. 423-429
Carlton, J. G., Martin-Serrano, J., Parallels between cytokinesis and retroviral budding: A role for the ESCRT machinery (2007) Science, 316 (5833), pp. 1908-1912
Skehel, J. J., Wiley, D. C., Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin (2000) Annu. Rev. Biochem., 69, pp. 531-569
Bieniasz, P. D., Late budding domains and host proteins in enveloped virus release (2006) Virology, 344 (1), pp. 55-63
Nickerson, D. P., Russell, M. R. G., Odorizzi, G., A concentric circle model of multivesicular body cargo sorting (2007) EMBO Rep., 8 (7), pp. 644-650
Gottlinger, H. G., Dorfman, T., Sodroski, J. G., Haseltine, W. A., Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release (1991) Proc. Natl. Acad. Sci. USA, 88 (3), pp. 3195-3199
Wills, J. W., Cameron, C. E., Wilson, C. B., Xiang, Y., Bennett, R. P., Leis, J., An assembly domain of the Rous sarcoma virus Gag protein required late in budding (1994) J. Virol., 68 (10), pp. 6605-6618
Jin, H., Leser, G. P., Zhang, J., Lamb, R. A., Influenza virus hemagglutinin and neuraminidase cytoplasmic tails control particle shape (1997) EMBO J., 16 (6), pp. 1236-1247
Shnyrova, A. V., Ayllon, J., Mikhalyov, I. I., Villar, E., Zimmerberg, J., Frolov, V. A., Vesicle formation by self-assembly of membrane-bound matrix proteins into a fluidlike budding domain (2007) J. Cell Biol., 179 (4), pp. 627-633
Schmitt, A. P., Lamb, R. A., Escaping from the cell: Assembly and budding of negative-strand RNA viruses (2004) Curr. Top. Microbiol. Immunol., 283, pp. 145-196
Sheetz, M. P., Painter, R. G., Singer, S. J., Biological membranes as bilayer couples. III. Compensatory shape changes induced in membranes (1976) J. Cell Biol., 70 (1), pp. 193-203
Lee, M. C., Orci, L., Hamamoto, S., Futai, E., Ravazzola, M., Schekman, R., Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle (2005) Cell, 122 (4), pp. 605-617
Ford, M. G., Mills, I. G., Peter, B. J., Vallis, Y., Praefcke, G. J., Evans, P. R., McMahon, H. T., Curvature of clathrin-coated pits driven by epsin (2002) Nature, 419 (6905), pp. 361-366
Gallop, J. K., Jao, C. C., Kent, H. M., Butler, P. J., Evans, P. R., Langen, R., McMahon, H. T., Mechanism of endophilin N-BAR domain-mediated membrane curvature (2006) EMBO J., 25 (12), pp. 2898-2910
Robison, C. S., Whitt, M. A., The membrane-proximal stem region of vesicular stomatitis virus G protein confers efficient virus assembly (2000) J. Virol., 74 (5), pp. 2239-2246
Sanz, M. A., Madan, V., Carrasco, L., Nieva, J. L., Interfacial domains in Sindbis virus 6K protein. Detection and functional characterization (2003) J. Biol. Chem., 278 (3), pp. 2051-2057
Owen, K. E., Kuhn, R. J., Alphavirus budding is dependent on the interaction between the nucleocapsid and hydrophobic amino acids on the cytoplasmic domain of the E2 envelope glycoprotein (1997) Virology, 230 (2), pp. 187-196
Barz, B., Wong, T. C., Kosztin, I., Membrane curvature and surface area per lipid affect the conformation and oligomeric state of HIV-1 fusion peptide: A combined FTIR and MD simulation study (2008) Biochim. et Biophys. Acta, 1778 (4), pp. 945-953
Membrane fusion and fission: enveloped viruses
Membrane fusion and fission are two key processes that occur during the replication of enveloped viruses, namely access to the interior of the host-cell (entry, which requires fusion of the viral envelope with the target cell envelope) and dissemination of viral progeny after replication (egress, which involves budding and fission). These dynamic processes are mediated by specialized proteins that modify and bend the lipid bilayer transiently and locally. This review focuses on fusion and fission reactions and on the hypothetical shared mechanism that generates their driving force.