Molecular imaging of drug resistance in cancer (438 views)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Mar; 21(1): 31-36.
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Paper type: Journal Article,
Impact factor: 0.268, 5-year impact factor: 0.291
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-67749089272&partnerID=40&md5=5947666545c6a7976a785808b7531a72
Keywords: Bcl-2, Drug Resistance, P-Glycoprotein, Abc Transporter, Erlotinib, Gefitinib, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Protein Bcl 2, Apoptosis, Cancer Cell Culture, Cell Membrane, Lung Cancer, Mitochondrial Permeability, Molecular Imaging, Multidrug Resistance, Review, Treatment Failure,
Affiliations:
*** IBB - CNR ***
Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
Institute of Biostructures and Bioimages of the National Research Council (CNR), Naples, Italy
References:
Szakacs, G., Paterson, J.K., Ludwig, J.A., Booth-Genthe, C., Gottesman, M.M., Targeting multidrug resistance in cancer (2006) Nat Rev Drug Discov, 5, pp. 219-23
Gottesman, M.M., Fojo, T., Bates, S.E., Multidrug resistance in cancer: Role of ATP-dependent transporters (2002) Nature Reviews Cancer, 2 (1), pp. 48-58
Leonard, G.D., Fojo, T., Bates, S.E., The role of ABC transporters in clinical practice (2003) Oncologist, 8 (5), pp. 411-424. , DOI 10.1634/theoncologist.8-5-411
Danial, N.N., Korsmeyer, S.J., Cell Death: Critical Control Points (2004) Cell, 116 (2), pp. 205-219. , DOI 10.1016/S0092-8674(04)00046-7
Igney, F.H., Krammer, P.H., Death and anti-death: Tumour resistance to apoptosis (2002) Nat Rev Cancer, 2, pp. 277-288
Johnstone, R.W., Ruefli, A.A., Lowe, S.W., Apoptosis: A link between cancer genetics and chemotherapy (2002) Cell, 108, pp. 153-164
Bassik, M.C., Scorrano, L., Oakes, S.A., Pozzan, T., Korsmeyer, S.J., Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis (2004) EMBO Journal, 23 (5), pp. 1207-1216. , DOI 10.1038/sj.emboj.7600104
Kroemer, G., Reed, J.C., Mitochondrial control of cell death (2000) Nat Med, 6, pp. 513-519
Cory, S., Adams, J.M., The BCL2 family: Regulators of the cellular life-or-death switch (2002) Nature Reviews Cancer, 2 (9), pp. 647-656. , DOI 10.1038/nrc883
Sharma, V., Radiopharmaceuticals for assessment of multidrug resistance P-glycoprotein-mediated drug transport activity (2004) Bioconjugate Chemistry, 15 (6), pp. 1464-1474. , DOI 10.1021/bc0498469
Piwnica-Worms, D., Kronauge, J.F., Chiu, M.L., Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium(I) in cultured chick myocardial cells. Mitochondrial and plasma membrane potential dependence (1990) Circulation, 82, pp. 1826-1838
Delmon-Moingeon, L.I., Piwnica-Worms, D., Van Den Abbeele, A.D., Holman, B.L., Davison, A., Uptake of the cation hexakis(2-methoxyisobutylisonitrile)-technetium- 99m by human carcinoma cell lines in vitro (1990) Cancer Res, 50, pp. 2198-2202
Carvalho, P.A., Chiu, M.L., Kronauge, J.F., Kawamura, M., Jones, A.G., Holman, B.L., Subcellular distribution and analysis of technetium-99m-MIBI in isolated perfused rat hearts (1992) J Nucl Med, 33, pp. 1516-1522
Hendrikse, N.H., Monitoring interactions at ATP-dependent drug efflux pumps (2000) Curr Pharm Des, 6, pp. 1653-1668
Moretti, J.-L., Azaloux, H., Boisseron, D., Kouyoumdjian, J.-C., Vilcoq, J., Primary breast cancer imaging with technetium-99m sestamibi and its relation with P-glycoprotein overexpression (1996) European Journal of Nuclear Medicine, 23 (8), pp. 980-986
Kostakoglu, L., Elahi, N., Kiratli, P., Ruacan, S., Sayek, I., Baltali, E., Sungur, A., Bekdik, C.F., Clinical validation of the influence of p-glycoprotein on technetium- 99m-sestamibi uptake in malignant tumors (1997) Journal of Nuclear Medicine, 38 (7), pp. 1003-1008
Del Vecchio, S., Carmiello, A., Potena, M.I., Carriero, M.V., Mainolfi, C., Botti, G., In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients (1997) Eur J Nucl Med, 24, pp. 150-159
Ciarmiello, A., Del Vecchio, S., Silvestro, P., Potena, M.I., Camera, M.V., Thomas, R., Botti, G., Salvatre, M., Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (1998) Journal of Clinical Oncology, 16 (5), pp. 1677-1683
Sciuto, R., Pasqualoni, R., Bergomi, S., Petrilli, G., Vici, P., Belli, F., Botti, C., Maini, C.L., Prognostic value of99mTc-sestamibi washout in predicting response of locally advanced breast cancer to neoadjuvant chemotherapy (2002) Journal of Nuclear Medicine, 43 (6), pp. 745-751
Takamura, Y., Miyoshi, Y., Taguchi, T., Noguchi, S., Prediction of chemotherapeutic response by Technetium 99m-MIBI scintigraphy in breast carcinoma patients (2001) Cancer, 92 (2), pp. 232-239. , DOI 10.1002/1097-0142(20010715)92:2<232::AID-CNCR1314> 3.0.CO
Mubashar, M., Harrington, K.J., Chaudhary, K.S., Lalani, E.-N., Stamp, G.W., Sinnett, D., Glass, D.M., Peters, A.M., 99mTc-sestamibi imaging in the assessment of toremifene as a modulator of multidrug resistance in patients with breast cancer (2002) Journal of Nuclear Medicine, 43 (4), pp. 519-525
Vaidyanathan, G., Zalutsky, M.R., Imaging drug resistance with radiolabeled molecules (2004) Current Pharmaceutical Design, 10 (24), pp. 2965-2979. , DOI 10.2174/1381612043383449
Shih, C.-M., Hsu, W.-H., Huang, W.-T., Wang, J.-J., Ho, S.-T., Kao, A., Usefulness of chest single photon emission computed tomography with technetium-99m methoxyisobutylisonitrile to predict taxol based chemotherapy response in advanced non-small cell lung cancer (2003) Cancer Letters, 199 (1), pp. 99-105. , DOI 10.1016/S0304-3835(03)00335-5
Kawata, K., Kanai, M., Sasada, T., Iwata, S., Yamamoto, N., Takabayashi, A., Usefulness of99mTc-sestamibi scintigraphy in suggesting the therapeutic effect of chemotherapy against gastric cancer (2004) Clinical Cancer Research, 10 (11), pp. 3788-3793. , DOI 10.1158/1078-0432.CCR-1072-3
Chang, C.S., Yang, S.S., Yeh, H.Z., Kao, C.H., Chen, G.H., Tc-99m MIBI liver imaging for hepatocellular carcinoma: Correlation with P-glycoprotein-multidrug-resistance gene expression (2004) Hepatogastroenterology, 51, pp. 211-214
Kostakoglu, L., Noninvasive detection of multidrug resistance in patients with hematological malignancies: Are we there yet? (2002) Clin Lymphoma, 2, pp. 242-248
Fonti, R., Del Vecchio, S., Zannetti, A., De Renzo, A., Catalano, L., Pace, L., Rotoli, B., Salvatore, M., Functional imaging of multidrug resistant phenotype by 99mTc-MIBI scan in patients with multiple myeloma (2004) Cancer Biotherapy and Radiopharmaceuticals, 19 (2), pp. 165-170. , DOI 10.1089/108497804323071931
Pusztai, L., Wagner, P., Ibrahim, N., Rivera, E., Theriault, R., Booser, D., Phase II study of tariquidar, a selective P-glycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma (2005) Cancer, 104, pp. 682-691
Bates, S.E., Bakke, S., Kang, M., Robey, R.W., Zhai, S., Thambi, P., Chen, C., Fojo, T., A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma (2004) Clinical Cancer Research, 10 (14), pp. 4724-4733. , DOI 10.1158/1078-0432.CCR-0829-03
Chen, C.C., Meadows, B., Regis, J., Kalafsky, G., Fojo, T., Carrasquillo, J.A., Bates, S.E., Detection of in vivo P-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi (1997) Clinical Cancer Research, 3 (4), pp. 545-552
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Aloj, L., Zannetti, A., Caraco, C., Del Vecchio, S., Salvatore, M., Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines (2004) European Journal of Nuclear Medicine and Molecular Imaging, 31 (4), pp. 521-527
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Herbst, R.S., Fukuoka, M., Baselga, J., Gefitinib - A novel targeted approach to treating cancer (2004) Nature Reviews Cancer, 4 (12), pp. 956-965. , DOI 10.1038/nrc1506
Weinstein, I.B., Cancer. Addiction to oncogenes - The Achilles heal of cancer (2002) Science, 297, pp. 63-64
Johnson, B.E., Janne, P.A., Epidermal growth factor receptor mutations in patients with non-small cell lung cancer (2005) Cancer Research, 65 (17), pp. 7525-7529. , DOI 10.1158/0008-5472.CAN-05-1257
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Costa, D.B., Halmos, B., Kumar, A., Schumer, S.T., Huberman, M.S., Boggon, T.J., Tenen, D.G., Kobayashi, S., BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations (2007) PLoS Medicine, 4 (10), pp. 1669-1680. , http://medicine.plosjournals.org/archive/1549-1676/4/10/pdf/10. 1371_journal.pmed.0040315-S.pdf, DOI 10.1371/journal.pmed.0040315
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Zannetti, A., Iommelli, F., Fonti, R., Papaccioli, A., Sommella, J., Lettieri, A., Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-x L modulation of inositol trisphosphate receptor type 3 (2008) Clin Cancer Res, 14, pp. 5209-5219
Orrenius, S., Zhivotovsky, B., Nicotera, P., Regulation of cell death: The calcium-apoptosis link (2003) Nature Reviews Molecular Cell Biology, 4 (7), pp. 552-565. , DOI 10.1038/nrm1150
Oakes, S.A., Scorrano, L., Opferman, J.T., Bassik, M.C., Nishino, M., Pozzan, T., Korsmeyer, S.J., Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum (2005) Proceedings of the National Academy of Sciences of the United States of America, 102 (1), pp. 105-110. , DOI 10.1073/pnas.0408352102
Chen, R., Valencia, I., Zhong, F., McColl, K.S., Roderick, H.L., Bootman, M.D., Berridge, M.J., Distelhorst, C.W., Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate (2004) Journal of Cell Biology, 166 (2), pp. 193-203. , DOI 10.1083/jcb.200309146
Gottesman, M. M., Fojo, T., Bates, S. E., Multidrug resistance in cancer: Role of ATP-dependent transporters (2002) Nature Reviews Cancer, 2 (1), pp. 48-58
Leonard, G. D., Fojo, T., Bates, S. E., The role of ABC transporters in clinical practice (2003) Oncologist, 8 (5), pp. 411-424. , DOI 10. 1634/theoncologist. 8-5-411
Danial, N. N., Korsmeyer, S. J., Cell Death: Critical Control Points (2004) Cell, 116 (2), pp. 205-219. , DOI 10. 1016/S0092-8674 (04) 00046-7
Igney, F. H., Krammer, P. H., Death and anti-death: Tumour resistance to apoptosis (2002) Nat Rev Cancer, 2, pp. 277-288
Johnstone, R. W., Ruefli, A. A., Lowe, S. W., Apoptosis: A link between cancer genetics and chemotherapy (2002) Cell, 108, pp. 153-164
Bassik, M. C., Scorrano, L., Oakes, S. A., Pozzan, T., Korsmeyer, S. J., Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis (2004) EMBO Journal, 23 (5), pp. 1207-1216. , DOI 10. 1038/sj. emboj. 7600104
Carvalho, P. A., Chiu, M. L., Kronauge, J. F., Kawamura, M., Jones, A. G., Holman, B. L., Subcellular distribution and analysis of technetium-99m-MIBI in isolated perfused rat hearts (1992) J Nucl Med, 33, pp. 1516-1522
Hendrikse, N. H., Monitoring interactions at ATP-dependent drug efflux pumps (2000) Curr Pharm Des, 6, pp. 1653-1668
Moretti, J. -L., Azaloux, H., Boisseron, D., Kouyoumdjian, J. -C., Vilcoq, J., Primary breast cancer imaging with technetium-99m sestamibi and its relation with P-glycoprotein overexpression (1996) European Journal of Nuclear Medicine, 23 (8), pp. 980-986
Shih, C. -M., Hsu, W. -H., Huang, W. -T., Wang, J. -J., Ho, S. -T., Kao, A., Usefulness of chest single photon emission computed tomography with technetium-99m methoxyisobutylisonitrile to predict taxol based chemotherapy response in advanced non-small cell lung cancer (2003) Cancer Letters, 199 (1), pp. 99-105. , DOI 10. 1016/S0304-3835 (03) 00335-5
Chang, C. S., Yang, S. S., Yeh, H. Z., Kao, C. H., Chen, G. H., Tc-99m MIBI liver imaging for hepatocellular carcinoma: Correlation with P-glycoprotein-multidrug-resistance gene expression (2004) Hepatogastroenterology, 51, pp. 211-214
Bates, S. E., Bakke, S., Kang, M., Robey, R. W., Zhai, S., Thambi, P., Chen, C., Fojo, T., A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma (2004) Clinical Cancer Research, 10 (14), pp. 4724-4733. , DOI 10. 1158/1078-0432. CCR-0829-03
Chen, C. C., Meadows, B., Regis, J., Kalafsky, G., Fojo, T., Carrasquillo, J. A., Bates, S. E., Detection of in vivo P-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi (1997) Clinical Cancer Research, 3 (4), pp. 545-552
Peck, R. A., Hewett, J., Harding, M. W., Wang, Y. -M., Chaturvedi, P. R., Bhatnagar, A., Ziessman, H., Hawkins, M. J., Phase I and pharmacokinetic study of the novel MDR1 and MRP1 inhibitor biricodar administered alone and in combination with doxorubicin (2001) Journal of Clinical Oncology, 19 (12), pp. 3130-3141
Hendrikse, N. H., Kuipers, F., Meijer, C., Havinga, R., Bijleveld, C. M., Van Der Graaf, W. T., In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein (2004) Cancer Chemother Pharmacol, 54, pp. 131-138
Herbst, R. S., Fukuoka, M., Baselga, J., Gefitinib - A novel targeted approach to treating cancer (2004) Nature Reviews Cancer, 4 (12), pp. 956-965. , DOI 10. 1038/nrc1506
Weinstein, I. B., Cancer. Addiction to oncogenes - The Achilles heal of cancer (2002) Science, 297, pp. 63-64
Johnson, B. E., Janne, P. A., Epidermal growth factor receptor mutations in patients with non-small cell lung cancer (2005) Cancer Research, 65 (17), pp. 7525-7529. , DOI 10. 1158/0008-5472. CAN-05-1257
Costa, D. B., Halmos, B., Kumar, A., Schumer, S. T., Huberman, M. S., Boggon, T. J., Tenen, D. G., Kobayashi, S., BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations (2007) PLoS Medicine, 4 (10), pp. 1669-1680. , http: //medicine. plosjournals. org/archive/1549-1676/4/10/pdf/10. 1371_journal. pmed. 0040315-S. pdf, DOI 10. 1371/journal. pmed. 0040315
Oakes, S. A., Scorrano, L., Opferman, J. T., Bassik, M. C., Nishino, M., Pozzan, T., Korsmeyer, S. J., Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum (2005) Proceedings of the National Academy of Sciences of the United States of America, 102 (1), pp. 105-110. , DOI 10. 1073/pnas. 0408352102
Minerva Biotecnol (ISSN: 1120-4826), 2009 Mar; 21(1): 31-36.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 0.268, 5-year impact factor: 0.291
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-67749089272&partnerID=40&md5=5947666545c6a7976a785808b7531a72
Keywords: Bcl-2, Drug Resistance, P-Glycoprotein, Abc Transporter, Erlotinib, Gefitinib, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Protein Bcl 2, Apoptosis, Cancer Cell Culture, Cell Membrane, Lung Cancer, Mitochondrial Permeability, Molecular Imaging, Multidrug Resistance, Review, Treatment Failure,
Affiliations:
*** IBB - CNR ***
Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
Institute of Biostructures and Bioimages of the National Research Council (CNR), Naples, Italy
References:
Szakacs, G., Paterson, J.K., Ludwig, J.A., Booth-Genthe, C., Gottesman, M.M., Targeting multidrug resistance in cancer (2006) Nat Rev Drug Discov, 5, pp. 219-23
Gottesman, M.M., Fojo, T., Bates, S.E., Multidrug resistance in cancer: Role of ATP-dependent transporters (2002) Nature Reviews Cancer, 2 (1), pp. 48-58
Leonard, G.D., Fojo, T., Bates, S.E., The role of ABC transporters in clinical practice (2003) Oncologist, 8 (5), pp. 411-424. , DOI 10.1634/theoncologist.8-5-411
Danial, N.N., Korsmeyer, S.J., Cell Death: Critical Control Points (2004) Cell, 116 (2), pp. 205-219. , DOI 10.1016/S0092-8674(04)00046-7
Igney, F.H., Krammer, P.H., Death and anti-death: Tumour resistance to apoptosis (2002) Nat Rev Cancer, 2, pp. 277-288
Johnstone, R.W., Ruefli, A.A., Lowe, S.W., Apoptosis: A link between cancer genetics and chemotherapy (2002) Cell, 108, pp. 153-164
Bassik, M.C., Scorrano, L., Oakes, S.A., Pozzan, T., Korsmeyer, S.J., Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis (2004) EMBO Journal, 23 (5), pp. 1207-1216. , DOI 10.1038/sj.emboj.7600104
Kroemer, G., Reed, J.C., Mitochondrial control of cell death (2000) Nat Med, 6, pp. 513-519
Cory, S., Adams, J.M., The BCL2 family: Regulators of the cellular life-or-death switch (2002) Nature Reviews Cancer, 2 (9), pp. 647-656. , DOI 10.1038/nrc883
Sharma, V., Radiopharmaceuticals for assessment of multidrug resistance P-glycoprotein-mediated drug transport activity (2004) Bioconjugate Chemistry, 15 (6), pp. 1464-1474. , DOI 10.1021/bc0498469
Piwnica-Worms, D., Kronauge, J.F., Chiu, M.L., Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium(I) in cultured chick myocardial cells. Mitochondrial and plasma membrane potential dependence (1990) Circulation, 82, pp. 1826-1838
Delmon-Moingeon, L.I., Piwnica-Worms, D., Van Den Abbeele, A.D., Holman, B.L., Davison, A., Uptake of the cation hexakis(2-methoxyisobutylisonitrile)-technetium- 99m by human carcinoma cell lines in vitro (1990) Cancer Res, 50, pp. 2198-2202
Carvalho, P.A., Chiu, M.L., Kronauge, J.F., Kawamura, M., Jones, A.G., Holman, B.L., Subcellular distribution and analysis of technetium-99m-MIBI in isolated perfused rat hearts (1992) J Nucl Med, 33, pp. 1516-1522
Hendrikse, N.H., Monitoring interactions at ATP-dependent drug efflux pumps (2000) Curr Pharm Des, 6, pp. 1653-1668
Moretti, J.-L., Azaloux, H., Boisseron, D., Kouyoumdjian, J.-C., Vilcoq, J., Primary breast cancer imaging with technetium-99m sestamibi and its relation with P-glycoprotein overexpression (1996) European Journal of Nuclear Medicine, 23 (8), pp. 980-986
Kostakoglu, L., Elahi, N., Kiratli, P., Ruacan, S., Sayek, I., Baltali, E., Sungur, A., Bekdik, C.F., Clinical validation of the influence of p-glycoprotein on technetium- 99m-sestamibi uptake in malignant tumors (1997) Journal of Nuclear Medicine, 38 (7), pp. 1003-1008
Del Vecchio, S., Carmiello, A., Potena, M.I., Carriero, M.V., Mainolfi, C., Botti, G., In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients (1997) Eur J Nucl Med, 24, pp. 150-159
Ciarmiello, A., Del Vecchio, S., Silvestro, P., Potena, M.I., Camera, M.V., Thomas, R., Botti, G., Salvatre, M., Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (1998) Journal of Clinical Oncology, 16 (5), pp. 1677-1683
Sciuto, R., Pasqualoni, R., Bergomi, S., Petrilli, G., Vici, P., Belli, F., Botti, C., Maini, C.L., Prognostic value of99mTc-sestamibi washout in predicting response of locally advanced breast cancer to neoadjuvant chemotherapy (2002) Journal of Nuclear Medicine, 43 (6), pp. 745-751
Takamura, Y., Miyoshi, Y., Taguchi, T., Noguchi, S., Prediction of chemotherapeutic response by Technetium 99m-MIBI scintigraphy in breast carcinoma patients (2001) Cancer, 92 (2), pp. 232-239. , DOI 10.1002/1097-0142(20010715)92:2<232::AID-CNCR1314> 3.0.CO
Mubashar, M., Harrington, K.J., Chaudhary, K.S., Lalani, E.-N., Stamp, G.W., Sinnett, D., Glass, D.M., Peters, A.M., 99mTc-sestamibi imaging in the assessment of toremifene as a modulator of multidrug resistance in patients with breast cancer (2002) Journal of Nuclear Medicine, 43 (4), pp. 519-525
Vaidyanathan, G., Zalutsky, M.R., Imaging drug resistance with radiolabeled molecules (2004) Current Pharmaceutical Design, 10 (24), pp. 2965-2979. , DOI 10.2174/1381612043383449
Shih, C.-M., Hsu, W.-H., Huang, W.-T., Wang, J.-J., Ho, S.-T., Kao, A., Usefulness of chest single photon emission computed tomography with technetium-99m methoxyisobutylisonitrile to predict taxol based chemotherapy response in advanced non-small cell lung cancer (2003) Cancer Letters, 199 (1), pp. 99-105. , DOI 10.1016/S0304-3835(03)00335-5
Kawata, K., Kanai, M., Sasada, T., Iwata, S., Yamamoto, N., Takabayashi, A., Usefulness of99mTc-sestamibi scintigraphy in suggesting the therapeutic effect of chemotherapy against gastric cancer (2004) Clinical Cancer Research, 10 (11), pp. 3788-3793. , DOI 10.1158/1078-0432.CCR-1072-3
Chang, C.S., Yang, S.S., Yeh, H.Z., Kao, C.H., Chen, G.H., Tc-99m MIBI liver imaging for hepatocellular carcinoma: Correlation with P-glycoprotein-multidrug-resistance gene expression (2004) Hepatogastroenterology, 51, pp. 211-214
Kostakoglu, L., Noninvasive detection of multidrug resistance in patients with hematological malignancies: Are we there yet? (2002) Clin Lymphoma, 2, pp. 242-248
Fonti, R., Del Vecchio, S., Zannetti, A., De Renzo, A., Catalano, L., Pace, L., Rotoli, B., Salvatore, M., Functional imaging of multidrug resistant phenotype by 99mTc-MIBI scan in patients with multiple myeloma (2004) Cancer Biotherapy and Radiopharmaceuticals, 19 (2), pp. 165-170. , DOI 10.1089/108497804323071931
Pusztai, L., Wagner, P., Ibrahim, N., Rivera, E., Theriault, R., Booser, D., Phase II study of tariquidar, a selective P-glycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma (2005) Cancer, 104, pp. 682-691
Bates, S.E., Bakke, S., Kang, M., Robey, R.W., Zhai, S., Thambi, P., Chen, C., Fojo, T., A phase I/II study of infusional vinblastine with the P-glycoprotein antagonist valspodar (PSC 833) in renal cell carcinoma (2004) Clinical Cancer Research, 10 (14), pp. 4724-4733. , DOI 10.1158/1078-0432.CCR-0829-03
Chen, C.C., Meadows, B., Regis, J., Kalafsky, G., Fojo, T., Carrasquillo, J.A., Bates, S.E., Detection of in vivo P-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi (1997) Clinical Cancer Research, 3 (4), pp. 545-552
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Chen, C. C., Meadows, B., Regis, J., Kalafsky, G., Fojo, T., Carrasquillo, J. A., Bates, S. E., Detection of in vivo P-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi (1997) Clinical Cancer Research, 3 (4), pp. 545-552
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Hendrikse, N. H., Kuipers, F., Meijer, C., Havinga, R., Bijleveld, C. M., Van Der Graaf, W. T., In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein (2004) Cancer Chemother Pharmacol, 54, pp. 131-138
Herbst, R. S., Fukuoka, M., Baselga, J., Gefitinib - A novel targeted approach to treating cancer (2004) Nature Reviews Cancer, 4 (12), pp. 956-965. , DOI 10. 1038/nrc1506
Weinstein, I. B., Cancer. Addiction to oncogenes - The Achilles heal of cancer (2002) Science, 297, pp. 63-64
Johnson, B. E., Janne, P. A., Epidermal growth factor receptor mutations in patients with non-small cell lung cancer (2005) Cancer Research, 65 (17), pp. 7525-7529. , DOI 10. 1158/0008-5472. CAN-05-1257
Costa, D. B., Halmos, B., Kumar, A., Schumer, S. T., Huberman, M. S., Boggon, T. J., Tenen, D. G., Kobayashi, S., BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations (2007) PLoS Medicine, 4 (10), pp. 1669-1680. , http: //medicine. plosjournals. org/archive/1549-1676/4/10/pdf/10. 1371_journal. pmed. 0040315-S. pdf, DOI 10. 1371/journal. pmed. 0040315
Oakes, S. A., Scorrano, L., Opferman, J. T., Bassik, M. C., Nishino, M., Pozzan, T., Korsmeyer, S. J., Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum (2005) Proceedings of the National Academy of Sciences of the United States of America, 102 (1), pp. 105-110. , DOI 10. 1073/pnas. 0408352102
Molecular imaging of drug resistance in cancer
Multidrug resistance remains the primary cause of treatment failure in cancer patients. Among the multiple cellular mechanisms underlying the resistant phenotype, the enhanced efflux of anticancer drugs mediated by members of the ATP-binding cassette family of transporters such as P-glycoprotein (Pgp) and the reduced apoptosis due to dysregulation of the process are the most common causes of drug resistance. Here we report the results of our studies on the possibility to detect in vivo and non-invasively malignant tumors that will become resistant to subsequent therapy using single-photon emission tomography and 99mTc-Sestamibi, a tumor-seeking agent currently used in clinical practice. This tracer is a lipophilic cation that accumulates in mitochondria in response to plasma membrane e mitochondrial membrane potentials. In addition, the tracer is subjected to Pgp-mediated outward transport thus mimicking the kinetic behaviour of anticancer drugs in resistant cells. Our studies showed that both the uptake and efflux mechanisms of 99mTc-Sestamibi can be helpful for the non-invasive assessment of drug resistance in cancer. While an enhanced tracer clearance is an index of Pgp-function, an altered pattern of tracer uptake is associated with an impaired apoptosis due to Bcl-2/Bcl-xL overexpression or unopposed action. In conclusion, molecular imaging of drug resistance is suitable and may provide biological information that can improve the efficacy of individual-tailored therapeutic strategies.
Multidrug resistance remains the primary cause of treatment failure in cancer patients. Among the multiple cellular mechanisms underlying the resistant phenotype, the enhanced efflux of anticancer drugs mediated by members of the ATP-binding cassette family of transporters such as P-glycoprotein (Pgp) and the reduced apoptosis due to dysregulation of the process are the most common causes of drug resistance. Here we report the results of our studies on the possibility to detect in vivo and non-invasively malignant tumors that will become resistant to subsequent therapy using single-photon emission tomography and 99mTc-Sestamibi, a tumor-seeking agent currently used in clinical practice. This tracer is a lipophilic cation that accumulates in mitochondria in response to plasma membrane e mitochondrial membrane potentials. In addition, the tracer is subjected to Pgp-mediated outward transport thus mimicking the kinetic behaviour of anticancer drugs in resistant cells. Our studies showed that both the uptake and efflux mechanisms of 99mTc-Sestamibi can be helpful for the non-invasive assessment of drug resistance in cancer. While an enhanced tracer clearance is an index of Pgp-function, an altered pattern of tracer uptake is associated with an impaired apoptosis due to Bcl-2/Bcl-xL overexpression or unopposed action. In conclusion, molecular imaging of drug resistance is suitable and may provide biological information that can improve the efficacy of individual-tailored therapeutic strategies.
Molecular imaging of drug resistance in cancer
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Petretta M, Acampa W, Zampella E, Assante R, Petretta MP, Cuocolo R, Fabiani I, Della Rattal GL, Perrone-Filardi P, Cuocolo A
* Imaging techniques for assessment of coronary flow reserve (400 views)
Monaldi Arch Chest Dis Card Ser (ISSN: 1122-0643, 1122-0643print), 2011 Dec; 76(4): 192-197.
Impact Factor: 7.132
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Di Paola R, Impellizzeri D, Salinaro AT, Mazzon E, Bellia F, Cavallaro M, Cornelius C, Vecchio G, Calabrese V, Rizzarelli E, Cuzzocrea S
* Administration of carnosine in the treatment of acute spinal cord injury (603 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2011 Nov 15; 82(10): 1478-1489.
Impact Factor: 4.705
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Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
* Assessment of cardiac sympathetic activity by MIBG imaging in patients with heart failure: a clinical appraisal (319 views)
Heart (ISSN: 1468-201x, 1355-6037), 2011 Nov; 97(22): 1828-1833.
Impact Factor: 4.223
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Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ
* Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity (880 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 279-304.
Impact Factor: 9.97
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Daniele S, Nappi C, Acampa W, Storto G, Pellegrino T, Ricci F, Xhoxhi E, Porcaro F, Petretta M, Cuocolo A
* Incremental prognostic value of coronary flow reserve assessed with single-photon emission computed tomography (427 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2011 Sep; 18(4): 612-619.
Impact Factor: 2.668
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Berti V, Sciagrà R, Acampa W, Ricci F, Cerisano G, Gallicchio R, Vigorito C, Pupi A, Cuocolo A
* Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction (369 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2011 Jun; 38(6): 1124-1131.
Impact Factor: 4.991
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Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (377 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
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Manganelli F, Spadafora M, Varrella P, Peluso G, Sauro R, Di Lorenzo E, Rosato G, Daniele S, Cuocolo A
* Addition of atropine to submaximal exercise stress testing in patients evaluated for suspected ischaemia with SPECT imaging: a randomized, placebo-controlled trial (357 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 Feb; 38(2): 245-251.
Impact Factor: 4.991
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Cicala S, Pellegrino T, Storto G, Caprio MG, Paladini R, Mainolfi C, de Leva F, Cuocolo A
* Noninvasive quantification of coronary endothelial function by SPECT imaging in children with a history of Kawasaki disease (384 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2010 Dec; 37(12): 2249-2255.
Impact Factor: 5.036
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Spadafora M, Varrella P, Acampa W, Spirito M, Nappi C, Mansi L, Miletto P, Rosato G, Cuocolo A
* Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction (414 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Sep; 37(9): 1730-1735.
Impact Factor: 5.036
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Perrone-Filardi P, Costanzo P, Dellegrottaglie S, Gargiulo P, Ruggiero D, Savarese G, Parente A, D'Amore C, Cuocolo A, Chiariello M
* Prognostic role of myocardial single photon emission computed tomography in the elderly (390 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2010 Apr; 17(2): 310-315.
Impact Factor: 2.811
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (578 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Acampa W, Caprio MG, Nicolai E, Liuzzi R, Capasso E, Luongo L, Petretta M, Cuocolo A
* Assessment of poststress left ventricular ejection fraction by gated SPECT: Comparison with equilibrium radionuclide angiocardiography (460 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Feb; 37(2): 349-356.
Impact Factor: 5.036
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Sorriento D, Iaccarino G, Trimarco B
The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy (410 views)
High Blood Press Cardiovasc Prev High Blood Pressure And Cardiovascular Prevention (ISSN: 1120-9879), 2010; 17(4): 209-217.
Impact Factor: 0
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Storto G, Soricelli A, Pellegrino T, Petretta M, Cuocolo A
* Assessment of the arterial input function for estimation of coronary flow reserve by single photon emission computed tomography: comparison of two different approaches (1958 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Dec; 36(12): 2034-2041.
Impact Factor: 4.531
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Lucignani G, Cuocolo A
Recent advances in the assessment of myocardial viability (358 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Nov; 36(11): 1892-1895.
Impact Factor: 4.531
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Fabbricini R, Catalano L, Pace L, Del Vecchio S, Fonti R, Salvatore M, Rotoli B
* Bone scintigraphy and SPECT/CT in bisphosphonate-induced osteonecrosis of the jaw (287 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2009 Aug; 50(8): 1385-1385.
Impact Factor: 6.424
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Di Fiore A, Fiorentino G, Vitale RM, Ronca R, Amodeo P, Pedone C, Bartolucci S, De Simone G
* Structural analysis of BldR from Sulfolobus solfataricus provides insights into the molecular basis of transcriptional activation in Archaea by MarR family proteins (470 views)
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 May 8; 388(3): 559-569.
Impact Factor: 3.871
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Evangelista L, Acampa W, Petretta M, Ferro A, Ricci F, Luongo L, Daniele S, Punzo G, Cuocolo A
* Incremental prognostic value of cardiac single-photon emission computed tomography after nitrate administration in patients with ischemic left ventricular dysfunction (422 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2009 Feb; 16(1): 38-44.
Impact Factor: 2.777
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Insabato L, Amelio I, Quarto M, Zannetti A, Tolino F, De Mauro G, Cerchia L, Riccio P, Baumhoer D, Condorelli G, Terracciano L, De Franciscis V
* Elevated Expression of the Tyrosine Phosphatase SHP-1 Defines a Subset of High-Grade Breast Tumors (448 views)
Oncology (ISSN: 0030-2414), 2009; 77(6): 378-384.
Impact Factor: 2.112
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Ruvo M, Sandomenico A, Marasco D, Monti SM, Tizzano B, De Capua A, Pedone C, Saporito A, Vitale RM, Formisano S, Stilo R, Liguoro D
* Self-association regions in the CARD of Bcl-10 (364 views)
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 569-570.
Impact Factor: 2.02
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Petretta M, Costanzo P, Acampa W, Imbriaco M, Ferro A, Filardi PP, Cuocolo A
* Noninvasive assessment of coronary anatomy and myocardial perfusion: Going toward an integrated imaging approach (373 views)
J Cardiovasc Med (ISSN: 1558-2027, 1558-2035), 2008 Oct; 9(10): 977-986.
Impact Factor: 1.407
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Zannetti A, Iommelli F, Fonti R, Papaccioli A, Sommella J, Lettieri A, Pirozzi G, Bianco R, Tortora G, Salvatore M, Del Vecchio S
* Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-xL modulation of inositol trisphosphate receptor type (537 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2008 Aug 15; 14(16): 5209-5219.
Impact Factor: 6.488
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (416 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
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Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (572 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (546 views)
J Nucl Med (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.
Impact Factor: 6.662
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Petretta M, Acampa W, Evangelista L, Daniele S, Ferro A, Cuocolo A
* Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (309 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 100-104.
Impact Factor: 2.442
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Wolak A, Slomka PJ, Fish MB, Lorenzo S, Acampa W, Berman DS, Germano G
* Quantitative myocardial-perfusion SPECT: Comparison of three state-of-the-art software packages (503 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 27-34.
Impact Factor: 2.442
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Ferro A, Pellegrino T, Spinelli L, Acampa W, Petretta M, Cuocolo A
* Comparison Between Dobutamine Echocardiography and Single-Photon Emission Computed Tomography for Interpretive Reproducibility (334 views)
Am J Cardiol (ISSN: 0002-9149), 2007 Oct 15; 100(8): 1239-1244.
Impact Factor: 3.603
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Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Petretta M, Cuocolo A
* Assessment of coronary flow reserve by sestamibi imaging in patients with typical chest pain and normal coronary arteries (355 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Sep; 34(8): 1156-1161.
Impact Factor: 4.101
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Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (616 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
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Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (412 views)
Ann Hematol (ISSN: 0939-5555, 0939-5555linking), 2007 Jun; 86(6): 415-423.
Impact Factor: 2.342
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Storto G, Pellegrino T, Sorrentino AR, Luongo L, Petretta M, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries (322 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
Impact Factor: 2.359
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Berisio R, Corti N, Pfister P, Yonath A, Böttger EC
* 23S rRNA 2058A→G alteration mediates ketolide resistance in combination with deletion in L22 (400 views)
Antimicrob Agents Ch (ISSN: 0066-4804, 1098-6596), 2006 Nov; 50(11): 3816-3823.
Impact Factor: 4.153
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Cuocolo A, Acampa W, Varrone A, Salvatore M
* Highlights of the Annual Congress of the European Association of Nuclear Medicine, Istanbul, 2005: The incremental value of nuclear medicine for patient management and care (584 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Mar; 33(3): 360-381.
Impact Factor: 4.041
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Pace L, Salvatore M, Del Vecchio S
* Use of Tc-99m-Sestamibi scintigraphy in multiple myeloma (241 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2006 Mar; 47(3): 555-555.
Impact Factor: 4.986
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Del Vecchio S, Zannetti A, Salvatore B, Paone G, Fonti R, Salvatore M
* Functional imaging of multidrug resistance in breast cancer (408 views)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2006; 21(SUPPL.1): 24-27.
Impact Factor: 0.313
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Pellegrino T, Storto G, Filardi PP, Sorrentino AR, Silvestro A, Petretta M, Brevetti G, Chiariello M, Salvatore M, Cuocolo A
* Relationship between brachial artery flow-mediated dilation and coronary flow reserve in patients with peripheral artery disease (330 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Dec; 46(12): 1997-2002.
Impact Factor: 4.684
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Perrone-Filardi P, Cuocolo A, Brevetti G, Silvestro A, Storto G, Dellegrottaglie S, Corrado L, Cafiero M, Camerino R, Polimeno M, Zarrilli A, Caiazzo G, Maglione A, Petretta A, Chiariello M
* Sodium and diseases in the aged (260 views)
Clin Ter, 2005 Nov 1; 138(5-6): 199-205.
Impact Factor: 0.329
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (350 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
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Catalano L, Andretta C, Pace L, Del Vecchio S, Salvatore B, De Rosa G, Buonanno MT, Paone G, Rotoli B
* Tc 99-Sesta Mibi Uptake In Nonsecretory Multiple Myeloma (369 views)
Hematology (ISSN: 1024-5332), 2005 Sep; 10(4): 335-338.
Impact Factor: 1.189
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Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Salvatore B, Andretta C, Di Nuzzo C, Rotoli B, Salvatore M
* Washout of [99mTc] sestamibi in predicting response to chemotherapy in patients with multiple myeloma (381 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Sep; 49(3): 281-285.
Impact Factor: 1.724
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Acampa W, Petretta M, Spinelli L, Ibello F, De Lauro F, Sansone V, Salvatore M, Cuocolo A
* Survival benefit after revascularization is independent of left ventricular ejection fraction improvement in patients with previous myocardial infarction and viable myocardium (282 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Apr; 32(4): 430-437.
Impact Factor: 3.883
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Acampa W, Spinelli L, Petretta M, De Lauro F, Ibello F, Cuocolo A
* Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: Direct comparison of stress echocardiography and myocardial perfusion imaging (290 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Mar; 46(3): 417-423.
Impact Factor: 4.684
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Cuocolo A, Acampa W, Imbriaco M, De Luca N, Iovino GL, Salvatore M
* The many ways to myocardial perfusion imaging (472 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Mar; 49(1): 4-18.
Impact Factor: 1.724
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Pace L, Del Vecchio S, Salvatore M
* Technetium 99m sestamibi in multiple myeloma (273 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005 Jan; 234(1): 312-313.
Impact Factor: 5.377
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Filippo C, Mariangela C, Giuseppina F, Pier Luigi C, Angelo B, Marco C, Giuseppe B, Paolo B, Ferdinando N, Agata C, Maria Angela S
* Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against β-amyloid toxicity (797 views)
Brain Res (ISSN: 0006-8993), 2005; 1047(1): 30-37.
Impact Factor: 2.296
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Pace L, Del Vecchio S, Salvatore M, Walker RC, Angtuaco E, Sethi R, Fassas A, Barlogie B
* Technetium 99m sestamibi in multiple myeloma [3] (multiple letters) (339 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005; 234(1): 312-313.
Impact Factor: 5.377
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Petretta M, Storto G, Acampa W, Sansone V, Evangelista L, Spinelli L, Cuocolo A
* Relation between wall thickening on gated perfusion SPECT and functional recovery after coronary revascularization in patients with previous myocardial infarction (372 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Dec; 31(12): 1599-1605.
Impact Factor: 3.935
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Storto G, Cirillo P, Eufrasia Vicario ML, Pellegrino T, Sorrentino AR, Petretta M, Galasso G, De Sanctis V, Piscione F, Cuocolo A
* Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: Comparison with the results of intracoronary Doppler technique (421 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2004 Nov; 11(6): 682-688.
Impact Factor: 1.849
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Del Vecchio S, Salvatore M
* Tc-99m-MIBI in the evaluation of breast cancer biology (600 views) (PDF 182 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Jun; 31(SUPPL.1): S88-S88.
Impact Factor: 3.935
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Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (694 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
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Aloj L, Zannetti A, Caracó C, Del Vecchio S, Salvatore M
* Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines (555 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004; 31(4): 521-527.
Impact Factor: 3.935
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Catalano L, Andretta C, Pace L, Del Vecchio S, Fonti R, Pollio G, Salvatore B, Esposito C, Salvatore M, Rotoli B
* Follow-Up Of Solitary Plasmacytoma By 99mtc-Sestamibi Scintigraphy (354 views)
Haema (ISSN: 1108-2682), 2004; 7(3): 329-334.
Impact Factor: 0
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Catalano L, Pace L, Rotoli B, Salvatore M
* Functional Imaging Of Multidrug Resistant Phenotype By 99mtc-Mibi Scan In Patients With Multiple Myeloma (461 views)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2004; 19(2): 165-170.
Impact Factor: 1.091
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Pace L, Salvatore M, Del Vecchio S
* A new role for nuclear medicine in multiple Myeloma (322 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Sep; 44(8): 1369-1369.
Impact Factor: 4.899
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Spinelli L, Petretta M, Acampa W, He W, Petretta A, Bonaduce D, Cuocolo A
* Prognostic value of combined assessment of regional left ventricular function and myocardial perfusion by dobutamine and rest gated SPECT in patients with uncomplicated acute myocardial infarction (429 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Jul; 44(7): 1023-1029.
Impact Factor: 4.899
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Berisio R, Harms J, Schluenzen F, Zarivach R, Hansen HAS, Fucini P, Yonath A
* Structural insight into the antibiotic action of telithromycin against resistant mutants (418 views)
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2003 Jul; 185(14): 4276-4279.
Impact Factor: 4.175
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Andretta C, Catalano L, Pace L, Fonti R, Annunziata G, Rotoli B
* 99mTc-sestaMIBI scintigraphy in thalidomide-treated refractory or relapsed multiple myeloma patients [2] (304 views)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2003 Jun; 44(6): 1081-1082.
Impact Factor: 1.163
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (527 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (463 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
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Acampa W, Petretta M, Florimonte L, Mattera A, Cuocolo A
* Prognostic value of exercise cardiac tomography performed late after percutaneous coronary intervention in symptomatic and symptom-free patients (383 views)
Am J Cardiol (ISSN: 0002-9149), 2003 Feb 1; 91(3): 259-263.
Impact Factor: 3.059
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Cuocolo A, Acampa W, Evangelista L
* Nuclear medicine and positron emission tomography imaging in cardiology (397 views)
Nucl Med Rev (ISSN: 1506-9680), 2003; 6(1): 59-63.
Impact Factor: 0.155
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Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (467 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Caracò C, Fonti R, Botti G, D'Aiuto G, Salvatore M
* Dynamic coupling of Tc-99m-MIBI efflux and apoptotic pathway activation in untreated breast cancer patients (483 views)
Eur J Nucl Med (ISSN: 1619-7070, 0340-6997, 1619-7089), 2002 Jun; 29(6): 809-814.
Impact Factor: 3.568
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Acampa W, He W, di Nuzzo C, Cuocolo A
* Quantification of SPECT myocardial perfusion imaging (352 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2002 May; 9(3): 338-342.
Impact Factor: 1.167
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Acampa W, Cuocolo A, Petretta M, Bruno A, Castellani M, Finzi A, Gerundini P
* Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: Comparison with sestamibi and Tl-201 scintigraphy (307 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2002 Jan; 9(1): 33-40.
Impact Factor: 1.167
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Petretta M, Acampa W, Cuocolo A
* Myocardial viability assessment in regions of left ventricular dysfunction. Part I: Radionuclide imaging and clinical implications (345 views)
Nuclear Medicine Communications (ISSN: 0143-3636, 1473-5628), 2001 Jun; 22(6): 607-611.
Impact Factor: 1.19
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Cuocolo A, Acampa W
* Nuclear cardiology in the new millennium (324 views)
Rev Esp Med Nucl (ISSN: 0212-6982), 2001 Jun; 20(4): 305-308.
Impact Factor: 0.155
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Pace L, Catalano L, Del Vecchio S, Di Gennaro F, De Renzo A, Sica G, Califano C, Tedesco N, Borrelli G, Rotoli B, Salvatore M
* Predictive value of technetium-99m sestamibi in patients with multiple myeloma and potential role in the follow-up (410 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Mar; 28(3): 304-312.
Impact Factor: 3.464
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Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (622 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (429 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(2): 214-220.
Impact Factor: 3.464
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Blocklet D, Schoutens A, Kentos A, Feremans W, Fonti R, Del Vecchio S, Pace L
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma [1] (multiple letters) (315 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(9): 1430-1432.
Impact Factor: 3.464
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Acampa W, Di Benedetto C, Cuocolo A
An overview of radiotracers in nuclear cardiology (376 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2000 Nov; 7(6): 701-707.
Impact Factor: 1.854
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Del Vecchio S, Ciarmiello A, Salvatore M
Scintigraphic detection of multidrug resistance in cancer (467 views)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2000 Sep; 15(4): 327-337.
Impact Factor: 0.989
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Cuocolo A, Acampa W, Nicolai E, Pace L, Petretta M, Salvatore M
Quantitative thallium-201 and technetium 99m sestamibi tomography at rest in detection of myocardial viability in patients with chronic ischemic left ventricular dysfunction (344 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2000 Jan; 7(1): 8-15.
Impact Factor: 1.854
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Spinelli L, Petretta M, Cuocolo A, Nicolai E, Acampa W, Vicario L, Bonaduce D
Prediction of recovery of left ventricular dysfunction after acute myocardial infarction: Comparison between Tc-99m-sestamibi cardiac tomography and low-dose dobutamine echocardiography (290 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1999 Oct; 40(10): 1683-1692.
Impact Factor: 3.326
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Herscher LL, Cook JA, Pacelli R, Pass HI, Russo A, Mitchell JB
Principles of chemoradiation: Theoretical and practical considerations (406 views)
Oncology (ISSN: 0890-9091), 1999 Oct; 13(10SUPPL.5): 11-22.
Impact Factor: 0.933
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Del Vecchio S, Ciarmiello A, Salvatore M
Clinical imaging of multidrug resistance in cancer (361 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1999 Jun; 43(2): 125-131.
Impact Factor: 2.125
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Gisonni P, Cuocolo A, Spinelli L, Acampa W, Florimonte L, Nicolai E, Petretta M, Sodano A
99mTc sestamibi cardiac tomography and dobutamine echocardiography in the identification of reversible left ventricular dysfunction in patients with acute myocardial infarction (284 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1999 Apr; 97(4): 265-270.
Impact Factor: 0.967
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Di Gennaro F, Catalano L, Pace L, de Renzo A, Pinto AM, del Vecchio S, Rotoli B, Salvatore M
Tc-99m sestamibi scintigraphy in multiple myeloma (272 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Feb; 24(2): 115-116.
Impact Factor: 0.253
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Fonti R, Levchenko A, Mehta BM, Zhang J, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography (312 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999 Jan; 26(1): 35-41.
Impact Factor: 1.623
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Catalano L, Pace L, Califano C, Pinto AM, De Renzo A, Di Gennaro F, Del Vecchio S, Fonti R, Salvatore M, Rotoli B
Detection of focal myeloma lesions by technetium-99m-sestaMIBI scintigraphy (358 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 1998 Nov 15; 92(10): 119-124.
Impact Factor: 1.876
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Pace L, Catalano L, Pinto A, De Renzo A, Di Gennaro F, Califano C, Del Vecchio S, Rotoli B, Salvatore M
Different patterns of technetium-99m sestamibi uptake in multiple myeloma (346 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1998 Jul; 25(7): 714-720.
Impact Factor: 2.564
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Acampa W, Cuocolo A, Sullo P, Varrone A, Nicolai E, Pace L, Petretta M, Salvatore M
Direct comparison of technetium 99m-sestamibi and technetium 99m-tetrofosmin cardiac single photon emission computed tomography in patients with coronary artery disease (443 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1998 May; 5(3): 265-274.
Impact Factor: 1.336
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Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (383 views)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
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Maurea S, Acampa W, Varrella P, De Rosa V, Fimiani P, Abate G, Salvatore M
Tc-99m sestamibi imaging in the diagnostic assessment of patients with lymphomas: Comparison with clinical and radiological evaluation (289 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1998 May; 23(5): 283-290.
Impact Factor: 0.283
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Ciarmiello A, Del Vecchio S, Silvestro P, Potena MI, Carriero MV, Thomas R, Botti G, D'Aiuto G, Salvatore M
Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (470 views)
Journal Of Clinical Oncology (ISSN: 0732-183x), 1998 May; 16(5): 1677-1683.
Impact Factor: 8.228
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Mansi L, Rambaldi PF, Cuccurullo V, Pecori B, Quarantelli M, Fallanca F, Del Vecchio E
Diagnostic and prognostic role of 99mTc-Tetrofosmin in breast cancer (297 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1997 Sep; 41(3): 239-250.
Impact Factor: 2.125
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Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Fractional retention of technetium-99m-sestamibi as an index of P- glycoprotein expression in untreated breast cancer patients (982 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Sep; 38(9): 1348-1351.
Impact Factor: 3.491
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Wang H, Maurea S, Mainolfi C, Fiore F, Gravina A, Panico M, Bazzicalupo L, Salvatore M
Tc-99m MIBI scintigraphy in patients with lung cancer comparison with CT and fluorine-18 FDG PET imaging (302 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1997 Apr; 22(4): 243-249.
Impact Factor: 0.34
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Vecchio SD, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Thomas R, Cerra M, D'Aiuto G, Tsuruo T, Salvatore M
In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients (328 views)
Eur J Nucl Med (ISSN: 0340-6997print, 0340-6997linking), 1997 Feb; 24(2): 150-159.
Impact Factor: 5.036
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Marcassa C, Galli M, Cuocolo A, Scappellato F, Maurea S, Salvatore M
Rest-redistribution thallium-201 and rest technetium-99m-sestamibi SPECT in patients with stable coronary artery disease and ventricular dysfunction (286 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997; 38(3): 419-424.
Impact Factor: 3.491
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Brunetti A, Alfano B, Soricelli A, Tedeschi E, Mainolfi C, Covelli EM, Aloj L, Panico M, Bazzicalupo L, Salvatore M
Functional characterization of brain tumors: An overview of the potential clinical value (746 views) (PDF 245 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 699-715.
Impact Factor: 1.042
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Iaffaioli RV, Facchini G, Tortoriello A, Scala S, Pacelli R, La Mura G, Pagliarulo C, Palmieri G, Caponigro F
Modulation of chemosensitivity by alpha interferon in multiple myeloma and non-Hodgkin's lymphoma (477 views)
J Exp Ther Oncol (ISSN: 1359-4117), 1996 Jul; 1(4): 226-230.
Impact Factor: 0
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Nappi A, Trimarco B, Salvatore M
Technetium-99m MIBI SPECT to identify viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction (297 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1996; 92(3): 289-296.
Impact Factor: 0.967
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Klain M, Maurea S, Cuocolo A, Colao A, Marzano L, Lombardi G, Salvatore M
Technetium-99m tetrofosmin imaging in thyroid diseases: Comparison with Tc-99m-pertechnetate, thallium-201 and Tc-99m-methioxyisobutylisonitrile scans (307 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1996; 23(12): 1568-1574.
Impact Factor: 2.692
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Klain M, Maurea S, Lastoria S, Cuocolo A, Colao A, Salvatore M
Technetium-99m-tetrofosmin imaging of differentiated mixed thyroid cancer (282 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Dec; 36(12): 2248-2251.
Impact Factor: 3.491
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Nappi A, Squame F, Imbriaco M, Trimarco B, Salvatore M
ENHANCED DETECTION OF VIABLE MYOCARDIUM BY TECHNETIUM-99M-MIBI IMAGING AFTER NITRATE ADMINISTRATION IN CHRONIC CORONARY-ARTERY DISEASE (245 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Nov; 36(11): 1945-1952.
Impact Factor: 3.491
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Squame F, Imbriaco M, De Luca N, Trimarco B, Salvatore M
MYOCARDIAL VIABILITY INDEX IN CHRONIC CORONARY-ARTERY DISEASE - TECHNETIUM-99M-METHOXY ISOBUTYL ISONITRILE REDISTRIBUTION (256 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Nov; 36(11): 1953-1960.
Impact Factor: 3.491
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Morisco C, Argenziano L, Salvatore M
Assessment of systolic wall thickening using technetium-99m methoxyisobutylisonitrile in patients with coronary artery disease: relation to thallium-201 scintigraphy with re-injection (322 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1995 Sep; 22(9): 1017-1022.
Impact Factor: 2.692
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Del Vecchio S, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Tsuruo T, Salvatore M
Quantitation of P-glycoprotein in sections of human breast carcinoma (298 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Ciarmiello A, Del Vecchio S, Potena MI, Mainolfi C, Carriero MV, Tsuruo T, Marone A, Salvatore M
Tc-99m-SESTAMIBI efflux and P-glycoprotein expression in human breast carcinoma (261 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Cuocolo A, Soricelli A, Pace L, Nicolai E, Castelli L, Nappi A, Imbriaco M, Morisco C, Ell PJ, Salvatore M
ADENOSINE TECHNETIUM-99M-METHOXY ISOBUTYL ISONITRILE MYOCARDIAL TOMOGRAPHY IN PATIENTS WITH CORONARY-ARTERY DISEASE - COMPARISON WITH EXERCISE (254 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Jul; 35(7): 1110-1115.
Impact Factor: 3.491
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Maurea S, Cuocolo A, Nicolai E, Salvatore M
Improved detection of viable myocardium with thallium-201 reinjection in chronic coronary artery disease: comparison with technetium-99m-MIBI imaging (292 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Apr; 35(4): 621-624.
Impact Factor: 3.491
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Cuocolo A, Pace L, Maurea S, Ricciardelli B, Nicolai E, Nappi A, Imbriaco M, Trimarco B, Salvatore M
Enhanced thallium-201 uptake after reinjection: Relation to regional ventricular function, myocardial perfusion and coronary anatomy (247 views)
J Nucl Med Allied Sci, 1994 Mar; 38(1): 6-13.
Impact Factor: 0
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Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
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Maurea S, Cuocolo A, Pace L, Nicolai E, Nappi A, Imbriaco M, Trimarco B, Salvatore M
Left ventricular dysfunction in coronary artery disease: Comparison between rest-redistribution thallium 201 and resting technetium 99m methoxyisobutyl isonitrile cardiac imaging (287 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1994 Jan; 1(1): 65-71.
Impact Factor: 1.878
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Imbriaco M, Cuocolo A, Pace L, Nicolai E, Nappi A, Celentano L, Palma G, Vosa C
Technetium-99m methoxy isobutyl isonitrile simultaneous evaluation of ventricular function and myocardial perfusion in patients with congenital heart disease (274 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1994 Jan; 19(1): 28-32.
Impact Factor: 0.34
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Cardei S, Morisco C, Argenziano L, Salvatore M
Ventricular systolic wall thickening by Technetium-99m methoxy-isobutyl-isonitrile. Relationship with coronary anatomy (261 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 88(1-2): 100-106.
Impact Factor: 0.967
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Cuocolo A, Maurea S, Pace L, Nicolai E, Nappi A, Imbriaco M, Trimarco B, Salvatore M
Resting technetium-99m methoxyisobutylisonitrile cardiac imaging in chronic coronary artery disease: comparison with rest-redistribution thallium-201 scintigraphy (323 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Dec; 20(12): 1186-1192.
Impact Factor: 2.692
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Maurea S, Cuocolo A, Pace L, Nicolai E, Nappi A, Imbriaco M, Morisco C, Chiariello M, Trimarco B, Salvatore M
Rest-injected thallium-201 redistribution and resting technetium-99m methoxyisobutylisonitrile uptake in coronary artery disease: relation to the severity of coronary artery stenosis (279 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Jun; 20(6): 502-510.
Impact Factor: 2.692
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SANTOMAURO M, CUOCOLO A, CELENTANO L, FERRARO S, PACE L, PAPPONE C, MADDALENA G, SALVATORE M, CHIARIELLO M
Diagnosis of coronary artery disease with Tc 99m-methoxy isobutil isonitrile and transesophageal pacing (379 views)
Angiology (ISSN: 0003-3197), 1992 Oct; 43(10): 818-825.
Impact Factor: 0.352
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Pace L, Cuocolo A, Nappi A, Nicolai E, Imbriaco M, Mangoni di Santo Stefano ML, Salvatore M
Myocardial scintigraphy with technetium 99m methoxyisobutylisonitrile. A comparison with coronary arteriography in patients with suspected ischemic cardiopathy (503 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 1992; 83(1-2): 97-100.
Impact Factor: 0.967
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Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
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* Molecular Immunology in Bacterial Vaccine Discovery (6 views)
Cells (ISSN: 2073-4409linking), 2022 Nov 28; 11(23): N/D-N/D.
Impact Factor: 7.7
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De Rosa V, Iommelli F, Terlizzi C, Leggiero E, Camerlingo R, Altobelli GG, Fonti R, Pastore L, Del Vecchio S
* Non-Canonical Role of PDK1 as a Negative Regulator of Apoptosis through Macromolecular Complexes Assembly at the ER-Mitochondria Interface in Oncogene-Driven NSCLC (16 views)
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Link W, Ilardi G, Zannetti A
* Editorial: Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression (18 views)
Front Oncol (ISSN: 2234-943xlinking), 2021 Aug 13; 11: 730815-730815.
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Susana F, Fagoonee S, Alessandro S, Valentina G, Chiara R, Marco P, Fiorella A, Danilo D
* Impedance-based drug-resistance characterization of colon cancer cells through real-time cell culture monitoring (82 views)
Talanta (ISSN: 0039-9140linking), 2021 Jan 15; 222: 121441-121441.
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Grund ME, Choi SJ, Mcnitt DH, Barbier M, Hu G, Lasala PR, Cote CK, Berisio R, Lukomski S
* Burkholderia collagen-like protein 8, Bucl8, is a unique outer membrane component of a putative tetrapartite efflux pump in Burkholderia pseudomallei and Burkholderia mallei (68 views)
Plosone (ISSN: 1932-6203linking, 1932-6203electronic), 2020 Nov 23; 15(11): e0242593-N/D.
Impact Factor: 2.74
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Russi S, Verma HK, Laurino S, Mazzone P, Storto G, Nardelli A, Zoppoli P, Calice G, La Rocca F, Sgambato A, Lucci V, Falco G, Ruggieri V
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Fagoonee S, Pellicano R
* Helicobacter pylori: molecular basis for colonization and survival in gastric environment and resistance to antibiotics. A short review (180 views)
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Husada F, Bountra K, Tassis K, De Boer M, Romano M, Rebuffat S, Beis S, Cordes T
* Conformational dynamics of the ABC transporter McjD seen by single-molecule FRET (114 views)
The Embo J, 2018 Nov; 2;37(21): N/D-N/D.
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Romano M, Fusco G, Choudhury H, G , Mehmood S, Robinson C, V , Zirah S, Hegemann J, D , Lescop E, Marahiel M, A , Rebuffat S, De Simone A, Beis K
* Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters (161 views)
Acs Chemical Biology, 2018 Jun; 13(6): 1598-1609.
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Nappi C, Nicolai E, Daniele S, Acampa W, Gaudieri V, Assante R, Zampella E, Segreto S, Imbriaco M, Petretta M, Salvatore M, Cuocolo A
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Impact Factor: 2.811
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Caviglia GP, Sguazzini C, Cisaro F, Ribaldone DG, Rosso C, Fagoonee S, Smedile A, Saracco GM, Astegiano M, Pellicano R
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Impact Factor: 2.863
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Dennehy R, RomanoM, Ruggiero A, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA, Berisio R, Mcclean S
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Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S
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Fonti R, Pace L, Cerchione C, Catalano L, Salvatore B, Pane F, Salvatore M, Del Vecchio S
* 18F-FDG PET/CT, 99mTc-MIBI, and MRI in the prediction of outcome of patients with multiple myeloma: a comparative study (432 views) (PDF 255 views)
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Impact Factor: 4.278
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Berisio R
* Editorial: Molecular determinants of bacterial diseases (354 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015; 22(14): 1640-1641.
Impact Factor: 3.455
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Marini C, Acampa W, Bauckneht M, Daniele S, Capitanio S, Cantoni V, Fiz F, Zampella E, Dib B, Assante R, Bruzzi P, Sambuceti G, Cuocolo A
* Added prognostic value of ischaemic threshold in radionuclide myocardial perfusion imaging: a common-sense integration of exercise tolerance and ischaemia severity (502 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2014 Dec 5; 42(5): 750-760.
Impact Factor: 5.383
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Iommelli F, De Rosa V, Gargiulo S, Panico M, Monti M, Greco A, Gramanzini M, Ortosecco G, Fonti R, Brunetti A, Del Vecchio S
* Monitoring Reversal of MET-Mediated Resistance to EGFR Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer Using 3 '-Deoxy-3 '-[F-18]-Fluorothymidine Positron Emission Tomography (513 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2014 Sep 15; 20(18): 4806-4815.
Impact Factor: 8.722
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D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, D'Armiento FP, Carlomagno C, Bianco F, Silvestro L, Pacelli R, Napolitano M, Iaffaioli RV, Scala S
* A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients (440 views)
Int J Cancer (ISSN: 0020-7136), 2014 Jul 15; 135(2): 379-390.
Impact Factor: 5.085
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Ruggiero A, Dattelbaum JD, Staiano M, Berisio R, D'Auria S, Vitagliano L
* A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima (437 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2014 May 15; 9(5): e96560-e96560.
Impact Factor: 3.234
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Storto G, Gallicchio R, Maddalena F, Pellegrino T, Petretta M, Fiumara G, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in patients with mild hypertension and normal coronary arteries (478 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1827-1936), 2014 Mar 14; 59(3): 336-341.
Impact Factor: 2.033
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Nold-Petry CA, Rudloff I, Baumer Y, Ruvo M, Marasco D, Botti P, Farkas L, Cho SX, Zepp JA, Azam T, Dinkel H, Palmer BE, Boisvert WA, Cool CD, Taraseviciene-Stewart L, Heinhuis B, Joosten LA, Dinarello CA, Voelkel NF, Nold MF
* IL-32 Promotes Angiogenesis (768 views)
J Immunol (ISSN: 0022-1767), 2014 Jan 15; 192(2): 589-602.
Impact Factor: 4.922
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Petretta M, Acampa W, Evangelista L, Daniele S, Zampella E, Assante R, Nappi C, Cantoni V, Fiumara G, Cuocolo A
* Reclassification of cardiovascular risk by myocardial perfusion imaging in diabetic patients with abnormal resting electrocardiogram (378 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2014; 24(6): 588-593.
Impact Factor: 3.323
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Ferro A, Petretta M, Acampa W, Fiumara G, Daniele S, Petretta MP, Cantoni V, Cuocolo A
* Post-stress left ventricular ejection fraction drop in patients with diabetes: A gated myocardial perfusion imaging study (346 views)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2013 Nov 14; 13: 99-99.
Impact Factor: 1.5
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Petretta M, Acampa W, Daniele S, Petretta MP, Plaitano M, Cuocolo A
* Transient ischemic dilation in patients with diabetes mellitus: prognostic value and effect on clinical outcome after coronary revascularization (346 views)
Circ Cardiovasc Imaging (ISSN: 1942-0080, 1941-9651), 2013 Nov; 6(6): 908-915.
Impact Factor: 1.783
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Greco A, Fiumara G, Gargiulo S, Gramanzini M, Brunetti A, Cuocolo A
* High-resolution positron emission tomography/computed tomography imaging of the mouse heart (466 views)
Exp Physiol Experimental Physiology (ISSN: 1469-445x, 0958-0670), 2013 Mar; 98(3): 645-651.
Impact Factor: 2.871
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Petretta M, Acampa W, Daniele S, Petretta MP, Nappi C, Assante R, Zampella E, Costanzo P, Perrone-Filardi P, Cuocolo A
* Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients (667 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2013 Feb; 20(1): 45-52.
Impact Factor: 2.645
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Bartolucci S, Contursi P, Fiorentino G, Limauro D, Pedone E
* Responding to toxic compounds: a genomic and functional overview of Archaea (702 views)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2013 Jan 1; 18: 165-189.
Impact Factor: 4.249
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Rosa R, Marciano R, Malapelle U, Formisano L, Nappi L, D'Amato C, D'Amato V, Damiano V, Marf G, Del Vecchio S, Zannetti A, Greco A, De Stefano A, Carlomagno C, Veneziani BM, Troncone G, De Placido S, Bianco R
* Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models (672 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2013 Jan 1; 19(1): 138-147.
Impact Factor: 8.193
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Del Giudice R, Monti DM, Truppo E, Arciello A, Supuran CT, De Simone G, Monti SM
* Human Carbonic Anhydrase Vii Protects Cells From Oxidative Damage (366 views)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1431-1673, 1437-4315), 2013; 394(10): 1343-1348.
Impact Factor: 2.689
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Galdiero S, Falanga A, Cantisani M, Tarallo R, della Pepa ME, D'Oriano V, Galdiero M
* Microbe-Host Interactions: Structure and Role of Gram-Negative Bacterial Porins (629 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 843-854.
Impact Factor: 2.326
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Perrone-filardi P, Cuocolo A, Dellegrottaglie S
Myocardial perfusion imaging in very elderly patients with suspected coronary artery disease: never too late! (387 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2012 Apr; 19(2): 224-226.
Impact Factor: 2.847
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Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
* 3'-deoxy-3'-18F-fluorothymidine (FLT) PET/CT to guide therapy with epidermal growth factor receptor (EGFR) antagonists and Bcl-xL inhibitors in non-small cell lung cancer (614 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2012 Mar 1; 53(3): 443-450.
Impact Factor: 5.774
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Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
* 3'-deoxy-3'-18F-fluorothymidine PET/CT to guide therapy with epidermal growth factor receptor antagonists and Bcl-xL inhibitors in non-small cell lung cancer (525 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2012 Mar 1; 53(3): 443-450.
Impact Factor: 5.774
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De Rosa A, Rinaldi C, Tucci T, Pappata S, Rossi F, Morra VB, Faggiano A, Colao A, De Michele G
* Co-existence of primary hyperparathyroidism and Parkinson's disease in three patients: An incidental finding? (379 views)
Parkinsonism Relat D (ISSN: 1353-8020, 1873-5126, 1873-5126electronic), 2011 Dec; 17(10): 771-773.
Impact Factor: 3.795
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Petretta M, Acampa W, Zampella E, Assante R, Petretta MP, Cuocolo R, Fabiani I, Della Rattal GL, Perrone-Filardi P, Cuocolo A
* Imaging techniques for assessment of coronary flow reserve (400 views)
Monaldi Arch Chest Dis Card Ser (ISSN: 1122-0643, 1122-0643print), 2011 Dec; 76(4): 192-197.
Impact Factor: 7.132
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Di Paola R, Impellizzeri D, Salinaro AT, Mazzon E, Bellia F, Cavallaro M, Cornelius C, Vecchio G, Calabrese V, Rizzarelli E, Cuzzocrea S
* Administration of carnosine in the treatment of acute spinal cord injury (603 views)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2011 Nov 15; 82(10): 1478-1489.
Impact Factor: 4.705
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Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
* Assessment of cardiac sympathetic activity by MIBG imaging in patients with heart failure: a clinical appraisal (319 views)
Heart (ISSN: 1468-201x, 1355-6037), 2011 Nov; 97(22): 1828-1833.
Impact Factor: 4.223
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Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ
* Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity (880 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 279-304.
Impact Factor: 9.97
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Daniele S, Nappi C, Acampa W, Storto G, Pellegrino T, Ricci F, Xhoxhi E, Porcaro F, Petretta M, Cuocolo A
* Incremental prognostic value of coronary flow reserve assessed with single-photon emission computed tomography (427 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2011 Sep; 18(4): 612-619.
Impact Factor: 2.668
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Berti V, Sciagrà R, Acampa W, Ricci F, Cerisano G, Gallicchio R, Vigorito C, Pupi A, Cuocolo A
* Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction (369 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2011 Jun; 38(6): 1124-1131.
Impact Factor: 4.991
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Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (377 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
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Manganelli F, Spadafora M, Varrella P, Peluso G, Sauro R, Di Lorenzo E, Rosato G, Daniele S, Cuocolo A
* Addition of atropine to submaximal exercise stress testing in patients evaluated for suspected ischaemia with SPECT imaging: a randomized, placebo-controlled trial (357 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 Feb; 38(2): 245-251.
Impact Factor: 4.991
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Cicala S, Pellegrino T, Storto G, Caprio MG, Paladini R, Mainolfi C, de Leva F, Cuocolo A
* Noninvasive quantification of coronary endothelial function by SPECT imaging in children with a history of Kawasaki disease (384 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2010 Dec; 37(12): 2249-2255.
Impact Factor: 5.036
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Spadafora M, Varrella P, Acampa W, Spirito M, Nappi C, Mansi L, Miletto P, Rosato G, Cuocolo A
* Direct imaging of viable myocardium by gated SPECT in patients with ischaemic left ventricular dysfunction (414 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Sep; 37(9): 1730-1735.
Impact Factor: 5.036
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Perrone-Filardi P, Costanzo P, Dellegrottaglie S, Gargiulo P, Ruggiero D, Savarese G, Parente A, D'Amore C, Cuocolo A, Chiariello M
* Prognostic role of myocardial single photon emission computed tomography in the elderly (390 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2010 Apr; 17(2): 310-315.
Impact Factor: 2.811
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (578 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Acampa W, Caprio MG, Nicolai E, Liuzzi R, Capasso E, Luongo L, Petretta M, Cuocolo A
* Assessment of poststress left ventricular ejection fraction by gated SPECT: Comparison with equilibrium radionuclide angiocardiography (460 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Feb; 37(2): 349-356.
Impact Factor: 5.036
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Sorriento D, Iaccarino G, Trimarco B
The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy (410 views)
High Blood Press Cardiovasc Prev High Blood Pressure And Cardiovascular Prevention (ISSN: 1120-9879), 2010; 17(4): 209-217.
Impact Factor: 0
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Storto G, Soricelli A, Pellegrino T, Petretta M, Cuocolo A
* Assessment of the arterial input function for estimation of coronary flow reserve by single photon emission computed tomography: comparison of two different approaches (1958 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Dec; 36(12): 2034-2041.
Impact Factor: 4.531
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Lucignani G, Cuocolo A
Recent advances in the assessment of myocardial viability (358 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Nov; 36(11): 1892-1895.
Impact Factor: 4.531
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Fabbricini R, Catalano L, Pace L, Del Vecchio S, Fonti R, Salvatore M, Rotoli B
* Bone scintigraphy and SPECT/CT in bisphosphonate-induced osteonecrosis of the jaw (287 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2009 Aug; 50(8): 1385-1385.
Impact Factor: 6.424
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Di Fiore A, Fiorentino G, Vitale RM, Ronca R, Amodeo P, Pedone C, Bartolucci S, De Simone G
* Structural analysis of BldR from Sulfolobus solfataricus provides insights into the molecular basis of transcriptional activation in Archaea by MarR family proteins (470 views)
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 May 8; 388(3): 559-569.
Impact Factor: 3.871
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Evangelista L, Acampa W, Petretta M, Ferro A, Ricci F, Luongo L, Daniele S, Punzo G, Cuocolo A
* Incremental prognostic value of cardiac single-photon emission computed tomography after nitrate administration in patients with ischemic left ventricular dysfunction (422 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2009 Feb; 16(1): 38-44.
Impact Factor: 2.777
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Insabato L, Amelio I, Quarto M, Zannetti A, Tolino F, De Mauro G, Cerchia L, Riccio P, Baumhoer D, Condorelli G, Terracciano L, De Franciscis V
* Elevated Expression of the Tyrosine Phosphatase SHP-1 Defines a Subset of High-Grade Breast Tumors (448 views)
Oncology (ISSN: 0030-2414), 2009; 77(6): 378-384.
Impact Factor: 2.112
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Ruvo M, Sandomenico A, Marasco D, Monti SM, Tizzano B, De Capua A, Pedone C, Saporito A, Vitale RM, Formisano S, Stilo R, Liguoro D
* Self-association regions in the CARD of Bcl-10 (364 views)
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 569-570.
Impact Factor: 2.02
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Petretta M, Costanzo P, Acampa W, Imbriaco M, Ferro A, Filardi PP, Cuocolo A
* Noninvasive assessment of coronary anatomy and myocardial perfusion: Going toward an integrated imaging approach (373 views)
J Cardiovasc Med (ISSN: 1558-2027, 1558-2035), 2008 Oct; 9(10): 977-986.
Impact Factor: 1.407
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Zannetti A, Iommelli F, Fonti R, Papaccioli A, Sommella J, Lettieri A, Pirozzi G, Bianco R, Tortora G, Salvatore M, Del Vecchio S
* Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-xL modulation of inositol trisphosphate receptor type (537 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2008 Aug 15; 14(16): 5209-5219.
Impact Factor: 6.488
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (416 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
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Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (572 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (546 views)
J Nucl Med (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.
Impact Factor: 6.662
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Petretta M, Acampa W, Evangelista L, Daniele S, Ferro A, Cuocolo A
* Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (309 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 100-104.
Impact Factor: 2.442
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Wolak A, Slomka PJ, Fish MB, Lorenzo S, Acampa W, Berman DS, Germano G
* Quantitative myocardial-perfusion SPECT: Comparison of three state-of-the-art software packages (503 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 27-34.
Impact Factor: 2.442
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Ferro A, Pellegrino T, Spinelli L, Acampa W, Petretta M, Cuocolo A
* Comparison Between Dobutamine Echocardiography and Single-Photon Emission Computed Tomography for Interpretive Reproducibility (334 views)
Am J Cardiol (ISSN: 0002-9149), 2007 Oct 15; 100(8): 1239-1244.
Impact Factor: 3.603
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Storto G, Sorrentino AR, Pellegrino T, Liuzzi R, Petretta M, Cuocolo A
* Assessment of coronary flow reserve by sestamibi imaging in patients with typical chest pain and normal coronary arteries (355 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Sep; 34(8): 1156-1161.
Impact Factor: 4.101
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Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (616 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
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Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (412 views)
Ann Hematol (ISSN: 0939-5555, 0939-5555linking), 2007 Jun; 86(6): 415-423.
Impact Factor: 2.342
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Storto G, Pellegrino T, Sorrentino AR, Luongo L, Petretta M, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries (322 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
Impact Factor: 2.359
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Berisio R, Corti N, Pfister P, Yonath A, Böttger EC
* 23S rRNA 2058A→G alteration mediates ketolide resistance in combination with deletion in L22 (400 views)
Antimicrob Agents Ch (ISSN: 0066-4804, 1098-6596), 2006 Nov; 50(11): 3816-3823.
Impact Factor: 4.153
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Cuocolo A, Acampa W, Varrone A, Salvatore M
* Highlights of the Annual Congress of the European Association of Nuclear Medicine, Istanbul, 2005: The incremental value of nuclear medicine for patient management and care (584 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Mar; 33(3): 360-381.
Impact Factor: 4.041
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Pace L, Salvatore M, Del Vecchio S
* Use of Tc-99m-Sestamibi scintigraphy in multiple myeloma (241 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2006 Mar; 47(3): 555-555.
Impact Factor: 4.986
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Del Vecchio S, Zannetti A, Salvatore B, Paone G, Fonti R, Salvatore M
* Functional imaging of multidrug resistance in breast cancer (408 views)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2006; 21(SUPPL.1): 24-27.
Impact Factor: 0.313
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Pellegrino T, Storto G, Filardi PP, Sorrentino AR, Silvestro A, Petretta M, Brevetti G, Chiariello M, Salvatore M, Cuocolo A
* Relationship between brachial artery flow-mediated dilation and coronary flow reserve in patients with peripheral artery disease (330 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Dec; 46(12): 1997-2002.
Impact Factor: 4.684
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Perrone-Filardi P, Cuocolo A, Brevetti G, Silvestro A, Storto G, Dellegrottaglie S, Corrado L, Cafiero M, Camerino R, Polimeno M, Zarrilli A, Caiazzo G, Maglione A, Petretta A, Chiariello M
* Sodium and diseases in the aged (260 views)
Clin Ter, 2005 Nov 1; 138(5-6): 199-205.
Impact Factor: 0.329
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (350 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
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Catalano L, Andretta C, Pace L, Del Vecchio S, Salvatore B, De Rosa G, Buonanno MT, Paone G, Rotoli B
* Tc 99-Sesta Mibi Uptake In Nonsecretory Multiple Myeloma (369 views)
Hematology (ISSN: 1024-5332), 2005 Sep; 10(4): 335-338.
Impact Factor: 1.189
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Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Salvatore B, Andretta C, Di Nuzzo C, Rotoli B, Salvatore M
* Washout of [99mTc] sestamibi in predicting response to chemotherapy in patients with multiple myeloma (381 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Sep; 49(3): 281-285.
Impact Factor: 1.724
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Acampa W, Petretta M, Spinelli L, Ibello F, De Lauro F, Sansone V, Salvatore M, Cuocolo A
* Survival benefit after revascularization is independent of left ventricular ejection fraction improvement in patients with previous myocardial infarction and viable myocardium (282 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Apr; 32(4): 430-437.
Impact Factor: 3.883
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Acampa W, Spinelli L, Petretta M, De Lauro F, Ibello F, Cuocolo A
* Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: Direct comparison of stress echocardiography and myocardial perfusion imaging (290 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Mar; 46(3): 417-423.
Impact Factor: 4.684
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Cuocolo A, Acampa W, Imbriaco M, De Luca N, Iovino GL, Salvatore M
* The many ways to myocardial perfusion imaging (472 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Mar; 49(1): 4-18.
Impact Factor: 1.724
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Pace L, Del Vecchio S, Salvatore M
* Technetium 99m sestamibi in multiple myeloma (273 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005 Jan; 234(1): 312-313.
Impact Factor: 5.377
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Filippo C, Mariangela C, Giuseppina F, Pier Luigi C, Angelo B, Marco C, Giuseppe B, Paolo B, Ferdinando N, Agata C, Maria Angela S
* Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against β-amyloid toxicity (797 views)
Brain Res (ISSN: 0006-8993), 2005; 1047(1): 30-37.
Impact Factor: 2.296
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Pace L, Del Vecchio S, Salvatore M, Walker RC, Angtuaco E, Sethi R, Fassas A, Barlogie B
* Technetium 99m sestamibi in multiple myeloma [3] (multiple letters) (339 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005; 234(1): 312-313.
Impact Factor: 5.377
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Petretta M, Storto G, Acampa W, Sansone V, Evangelista L, Spinelli L, Cuocolo A
* Relation between wall thickening on gated perfusion SPECT and functional recovery after coronary revascularization in patients with previous myocardial infarction (372 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Dec; 31(12): 1599-1605.
Impact Factor: 3.935
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Storto G, Cirillo P, Eufrasia Vicario ML, Pellegrino T, Sorrentino AR, Petretta M, Galasso G, De Sanctis V, Piscione F, Cuocolo A
* Estimation of coronary flow reserve by Tc-99m sestamibi imaging in patients with coronary artery disease: Comparison with the results of intracoronary Doppler technique (421 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2004 Nov; 11(6): 682-688.
Impact Factor: 1.849
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Del Vecchio S, Salvatore M
* Tc-99m-MIBI in the evaluation of breast cancer biology (600 views) (PDF 182 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Jun; 31(SUPPL.1): S88-S88.
Impact Factor: 3.935
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Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (694 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
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Aloj L, Zannetti A, Caracó C, Del Vecchio S, Salvatore M
* Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines (555 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004; 31(4): 521-527.
Impact Factor: 3.935
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Catalano L, Andretta C, Pace L, Del Vecchio S, Fonti R, Pollio G, Salvatore B, Esposito C, Salvatore M, Rotoli B
* Follow-Up Of Solitary Plasmacytoma By 99mtc-Sestamibi Scintigraphy (354 views)
Haema (ISSN: 1108-2682), 2004; 7(3): 329-334.
Impact Factor: 0
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Catalano L, Pace L, Rotoli B, Salvatore M
* Functional Imaging Of Multidrug Resistant Phenotype By 99mtc-Mibi Scan In Patients With Multiple Myeloma (461 views)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2004; 19(2): 165-170.
Impact Factor: 1.091
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Pace L, Salvatore M, Del Vecchio S
* A new role for nuclear medicine in multiple Myeloma (322 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Sep; 44(8): 1369-1369.
Impact Factor: 4.899
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Spinelli L, Petretta M, Acampa W, He W, Petretta A, Bonaduce D, Cuocolo A
* Prognostic value of combined assessment of regional left ventricular function and myocardial perfusion by dobutamine and rest gated SPECT in patients with uncomplicated acute myocardial infarction (429 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Jul; 44(7): 1023-1029.
Impact Factor: 4.899
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Berisio R, Harms J, Schluenzen F, Zarivach R, Hansen HAS, Fucini P, Yonath A
* Structural insight into the antibiotic action of telithromycin against resistant mutants (418 views)
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2003 Jul; 185(14): 4276-4279.
Impact Factor: 4.175
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Andretta C, Catalano L, Pace L, Fonti R, Annunziata G, Rotoli B
* 99mTc-sestaMIBI scintigraphy in thalidomide-treated refractory or relapsed multiple myeloma patients [2] (304 views)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2003 Jun; 44(6): 1081-1082.
Impact Factor: 1.163
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (527 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (463 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
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Acampa W, Petretta M, Florimonte L, Mattera A, Cuocolo A
* Prognostic value of exercise cardiac tomography performed late after percutaneous coronary intervention in symptomatic and symptom-free patients (383 views)
Am J Cardiol (ISSN: 0002-9149), 2003 Feb 1; 91(3): 259-263.
Impact Factor: 3.059
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Cuocolo A, Acampa W, Evangelista L
* Nuclear medicine and positron emission tomography imaging in cardiology (397 views)
Nucl Med Rev (ISSN: 1506-9680), 2003; 6(1): 59-63.
Impact Factor: 0.155
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Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (467 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Caracò C, Fonti R, Botti G, D'Aiuto G, Salvatore M
* Dynamic coupling of Tc-99m-MIBI efflux and apoptotic pathway activation in untreated breast cancer patients (483 views)
Eur J Nucl Med (ISSN: 1619-7070, 0340-6997, 1619-7089), 2002 Jun; 29(6): 809-814.
Impact Factor: 3.568
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Acampa W, He W, di Nuzzo C, Cuocolo A
* Quantification of SPECT myocardial perfusion imaging (352 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2002 May; 9(3): 338-342.
Impact Factor: 1.167
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Acampa W, Cuocolo A, Petretta M, Bruno A, Castellani M, Finzi A, Gerundini P
* Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: Comparison with sestamibi and Tl-201 scintigraphy (307 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2002 Jan; 9(1): 33-40.
Impact Factor: 1.167
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Petretta M, Acampa W, Cuocolo A
* Myocardial viability assessment in regions of left ventricular dysfunction. Part I: Radionuclide imaging and clinical implications (345 views)
Nuclear Medicine Communications (ISSN: 0143-3636, 1473-5628), 2001 Jun; 22(6): 607-611.
Impact Factor: 1.19
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Cuocolo A, Acampa W
* Nuclear cardiology in the new millennium (324 views)
Rev Esp Med Nucl (ISSN: 0212-6982), 2001 Jun; 20(4): 305-308.
Impact Factor: 0.155
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Pace L, Catalano L, Del Vecchio S, Di Gennaro F, De Renzo A, Sica G, Califano C, Tedesco N, Borrelli G, Rotoli B, Salvatore M
* Predictive value of technetium-99m sestamibi in patients with multiple myeloma and potential role in the follow-up (410 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Mar; 28(3): 304-312.
Impact Factor: 3.464
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Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (622 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
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Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma (429 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(2): 214-220.
Impact Factor: 3.464
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Blocklet D, Schoutens A, Kentos A, Feremans W, Fonti R, Del Vecchio S, Pace L
* Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma [1] (multiple letters) (315 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001; 28(9): 1430-1432.
Impact Factor: 3.464
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Acampa W, Di Benedetto C, Cuocolo A
An overview of radiotracers in nuclear cardiology (376 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2000 Nov; 7(6): 701-707.
Impact Factor: 1.854
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Del Vecchio S, Ciarmiello A, Salvatore M
Scintigraphic detection of multidrug resistance in cancer (467 views)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2000 Sep; 15(4): 327-337.
Impact Factor: 0.989
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Cuocolo A, Acampa W, Nicolai E, Pace L, Petretta M, Salvatore M
Quantitative thallium-201 and technetium 99m sestamibi tomography at rest in detection of myocardial viability in patients with chronic ischemic left ventricular dysfunction (344 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2000 Jan; 7(1): 8-15.
Impact Factor: 1.854
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Spinelli L, Petretta M, Cuocolo A, Nicolai E, Acampa W, Vicario L, Bonaduce D
Prediction of recovery of left ventricular dysfunction after acute myocardial infarction: Comparison between Tc-99m-sestamibi cardiac tomography and low-dose dobutamine echocardiography (290 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1999 Oct; 40(10): 1683-1692.
Impact Factor: 3.326
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Herscher LL, Cook JA, Pacelli R, Pass HI, Russo A, Mitchell JB
Principles of chemoradiation: Theoretical and practical considerations (406 views)
Oncology (ISSN: 0890-9091), 1999 Oct; 13(10SUPPL.5): 11-22.
Impact Factor: 0.933
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Del Vecchio S, Ciarmiello A, Salvatore M
Clinical imaging of multidrug resistance in cancer (361 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1999 Jun; 43(2): 125-131.
Impact Factor: 2.125
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Gisonni P, Cuocolo A, Spinelli L, Acampa W, Florimonte L, Nicolai E, Petretta M, Sodano A
99mTc sestamibi cardiac tomography and dobutamine echocardiography in the identification of reversible left ventricular dysfunction in patients with acute myocardial infarction (284 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1999 Apr; 97(4): 265-270.
Impact Factor: 0.967
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Di Gennaro F, Catalano L, Pace L, de Renzo A, Pinto AM, del Vecchio S, Rotoli B, Salvatore M
Tc-99m sestamibi scintigraphy in multiple myeloma (272 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Feb; 24(2): 115-116.
Impact Factor: 0.253
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Fonti R, Levchenko A, Mehta BM, Zhang J, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography (312 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999 Jan; 26(1): 35-41.
Impact Factor: 1.623
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Catalano L, Pace L, Califano C, Pinto AM, De Renzo A, Di Gennaro F, Del Vecchio S, Fonti R, Salvatore M, Rotoli B
Detection of focal myeloma lesions by technetium-99m-sestaMIBI scintigraphy (358 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 1998 Nov 15; 92(10): 119-124.
Impact Factor: 1.876
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Pace L, Catalano L, Pinto A, De Renzo A, Di Gennaro F, Califano C, Del Vecchio S, Rotoli B, Salvatore M
Different patterns of technetium-99m sestamibi uptake in multiple myeloma (346 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1998 Jul; 25(7): 714-720.
Impact Factor: 2.564
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Acampa W, Cuocolo A, Sullo P, Varrone A, Nicolai E, Pace L, Petretta M, Salvatore M
Direct comparison of technetium 99m-sestamibi and technetium 99m-tetrofosmin cardiac single photon emission computed tomography in patients with coronary artery disease (443 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1998 May; 5(3): 265-274.
Impact Factor: 1.336
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Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (383 views)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
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Maurea S, Acampa W, Varrella P, De Rosa V, Fimiani P, Abate G, Salvatore M
Tc-99m sestamibi imaging in the diagnostic assessment of patients with lymphomas: Comparison with clinical and radiological evaluation (289 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1998 May; 23(5): 283-290.
Impact Factor: 0.283
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Ciarmiello A, Del Vecchio S, Silvestro P, Potena MI, Carriero MV, Thomas R, Botti G, D'Aiuto G, Salvatore M
Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (470 views)
Journal Of Clinical Oncology (ISSN: 0732-183x), 1998 May; 16(5): 1677-1683.
Impact Factor: 8.228
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Mansi L, Rambaldi PF, Cuccurullo V, Pecori B, Quarantelli M, Fallanca F, Del Vecchio E
Diagnostic and prognostic role of 99mTc-Tetrofosmin in breast cancer (297 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1997 Sep; 41(3): 239-250.
Impact Factor: 2.125
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Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Fractional retention of technetium-99m-sestamibi as an index of P- glycoprotein expression in untreated breast cancer patients (982 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Sep; 38(9): 1348-1351.
Impact Factor: 3.491
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Wang H, Maurea S, Mainolfi C, Fiore F, Gravina A, Panico M, Bazzicalupo L, Salvatore M
Tc-99m MIBI scintigraphy in patients with lung cancer comparison with CT and fluorine-18 FDG PET imaging (302 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1997 Apr; 22(4): 243-249.
Impact Factor: 0.34
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Vecchio SD, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Thomas R, Cerra M, D'Aiuto G, Tsuruo T, Salvatore M
In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients (328 views)
Eur J Nucl Med (ISSN: 0340-6997print, 0340-6997linking), 1997 Feb; 24(2): 150-159.
Impact Factor: 5.036
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Marcassa C, Galli M, Cuocolo A, Scappellato F, Maurea S, Salvatore M
Rest-redistribution thallium-201 and rest technetium-99m-sestamibi SPECT in patients with stable coronary artery disease and ventricular dysfunction (286 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997; 38(3): 419-424.
Impact Factor: 3.491
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Brunetti A, Alfano B, Soricelli A, Tedeschi E, Mainolfi C, Covelli EM, Aloj L, Panico M, Bazzicalupo L, Salvatore M
Functional characterization of brain tumors: An overview of the potential clinical value (746 views) (PDF 245 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 699-715.
Impact Factor: 1.042
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Iaffaioli RV, Facchini G, Tortoriello A, Scala S, Pacelli R, La Mura G, Pagliarulo C, Palmieri G, Caponigro F
Modulation of chemosensitivity by alpha interferon in multiple myeloma and non-Hodgkin's lymphoma (477 views)
J Exp Ther Oncol (ISSN: 1359-4117), 1996 Jul; 1(4): 226-230.
Impact Factor: 0
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Nappi A, Trimarco B, Salvatore M
Technetium-99m MIBI SPECT to identify viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction (297 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1996; 92(3): 289-296.
Impact Factor: 0.967
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Klain M, Maurea S, Cuocolo A, Colao A, Marzano L, Lombardi G, Salvatore M
Technetium-99m tetrofosmin imaging in thyroid diseases: Comparison with Tc-99m-pertechnetate, thallium-201 and Tc-99m-methioxyisobutylisonitrile scans (307 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1996; 23(12): 1568-1574.
Impact Factor: 2.692
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Klain M, Maurea S, Lastoria S, Cuocolo A, Colao A, Salvatore M
Technetium-99m-tetrofosmin imaging of differentiated mixed thyroid cancer (282 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Dec; 36(12): 2248-2251.
Impact Factor: 3.491
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Nappi A, Squame F, Imbriaco M, Trimarco B, Salvatore M
ENHANCED DETECTION OF VIABLE MYOCARDIUM BY TECHNETIUM-99M-MIBI IMAGING AFTER NITRATE ADMINISTRATION IN CHRONIC CORONARY-ARTERY DISEASE (245 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Nov; 36(11): 1945-1952.
Impact Factor: 3.491
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Maurea S, Cuocolo A, Soricelli A, Castelli L, Squame F, Imbriaco M, De Luca N, Trimarco B, Salvatore M
MYOCARDIAL VIABILITY INDEX IN CHRONIC CORONARY-ARTERY DISEASE - TECHNETIUM-99M-METHOXY ISOBUTYL ISONITRILE REDISTRIBUTION (256 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Nov; 36(11): 1953-1960.
Impact Factor: 3.491
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Morisco C, Argenziano L, Salvatore M
Assessment of systolic wall thickening using technetium-99m methoxyisobutylisonitrile in patients with coronary artery disease: relation to thallium-201 scintigraphy with re-injection (322 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1995 Sep; 22(9): 1017-1022.
Impact Factor: 2.692
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Del Vecchio S, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Tsuruo T, Salvatore M
Quantitation of P-glycoprotein in sections of human breast carcinoma (298 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Ciarmiello A, Del Vecchio S, Potena MI, Mainolfi C, Carriero MV, Tsuruo T, Marone A, Salvatore M
Tc-99m-SESTAMIBI efflux and P-glycoprotein expression in human breast carcinoma (261 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Cuocolo A, Soricelli A, Pace L, Nicolai E, Castelli L, Nappi A, Imbriaco M, Morisco C, Ell PJ, Salvatore M
ADENOSINE TECHNETIUM-99M-METHOXY ISOBUTYL ISONITRILE MYOCARDIAL TOMOGRAPHY IN PATIENTS WITH CORONARY-ARTERY DISEASE - COMPARISON WITH EXERCISE (254 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Jul; 35(7): 1110-1115.
Impact Factor: 3.491
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Maurea S, Cuocolo A, Nicolai E, Salvatore M
Improved detection of viable myocardium with thallium-201 reinjection in chronic coronary artery disease: comparison with technetium-99m-MIBI imaging (292 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Apr; 35(4): 621-624.
Impact Factor: 3.491
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Cuocolo A, Pace L, Maurea S, Ricciardelli B, Nicolai E, Nappi A, Imbriaco M, Trimarco B, Salvatore M
Enhanced thallium-201 uptake after reinjection: Relation to regional ventricular function, myocardial perfusion and coronary anatomy (247 views)
J Nucl Med Allied Sci, 1994 Mar; 38(1): 6-13.
Impact Factor: 0
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Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
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Maurea S, Cuocolo A, Pace L, Nicolai E, Nappi A, Imbriaco M, Trimarco B, Salvatore M
Left ventricular dysfunction in coronary artery disease: Comparison between rest-redistribution thallium 201 and resting technetium 99m methoxyisobutyl isonitrile cardiac imaging (287 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1994 Jan; 1(1): 65-71.
Impact Factor: 1.878
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Imbriaco M, Cuocolo A, Pace L, Nicolai E, Nappi A, Celentano L, Palma G, Vosa C
Technetium-99m methoxy isobutyl isonitrile simultaneous evaluation of ventricular function and myocardial perfusion in patients with congenital heart disease (274 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1994 Jan; 19(1): 28-32.
Impact Factor: 0.34
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Cardei S, Morisco C, Argenziano L, Salvatore M
Ventricular systolic wall thickening by Technetium-99m methoxy-isobutyl-isonitrile. Relationship with coronary anatomy (261 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 88(1-2): 100-106.
Impact Factor: 0.967
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Cuocolo A, Maurea S, Pace L, Nicolai E, Nappi A, Imbriaco M, Trimarco B, Salvatore M
Resting technetium-99m methoxyisobutylisonitrile cardiac imaging in chronic coronary artery disease: comparison with rest-redistribution thallium-201 scintigraphy (323 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Dec; 20(12): 1186-1192.
Impact Factor: 2.692
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Maurea S, Cuocolo A, Pace L, Nicolai E, Nappi A, Imbriaco M, Morisco C, Chiariello M, Trimarco B, Salvatore M
Rest-injected thallium-201 redistribution and resting technetium-99m methoxyisobutylisonitrile uptake in coronary artery disease: relation to the severity of coronary artery stenosis (279 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Jun; 20(6): 502-510.
Impact Factor: 2.692
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SANTOMAURO M, CUOCOLO A, CELENTANO L, FERRARO S, PACE L, PAPPONE C, MADDALENA G, SALVATORE M, CHIARIELLO M
Diagnosis of coronary artery disease with Tc 99m-methoxy isobutil isonitrile and transesophageal pacing (379 views)
Angiology (ISSN: 0003-3197), 1992 Oct; 43(10): 818-825.
Impact Factor: 0.352
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Pace L, Cuocolo A, Nappi A, Nicolai E, Imbriaco M, Mangoni di Santo Stefano ML, Salvatore M
Myocardial scintigraphy with technetium 99m methoxyisobutylisonitrile. A comparison with coronary arteriography in patients with suspected ischemic cardiopathy (503 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 1992; 83(1-2): 97-100.
Impact Factor: 0.967
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Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
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150 Records (141 excluding Abstracts).
Total impact factor: 478.613 (451.865 excluding Abstracts).
Total 5 year impact factor: 553.56 (515.118 excluding Abstracts).
Total impact factor: 478.613 (451.865 excluding Abstracts).
Total 5 year impact factor: 553.56 (515.118 excluding Abstracts).
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