Ribosome's mode of function: Myths, facts and recent results
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Ribosome's mode of function: Myths, facts and recent results
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552 views
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Wekselman I, Davidovich C, Agmon I, Zimmerman E, Rozenberg H, Bashan A,
Berisio R
, Yonath A
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print)
,
2009 Mar;
15(3): 122-130.
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Paper type:
Journal Article,
Impact factor:
1.807,
5-year impact factor:
1.872
Url:
http://www.scopus.com/inward/record.url?eid=2-s2.0-63449099344&partnerID=40&md5=aa96247ad45adc4e30b77f0c20ac004a
Keywords:
Antibiotics, Nanomachine, Peptide Biosynthesis, Ribosome, Tunnel, X-Ray Crystallography, Peptidyltransferase, Ribosome Protein, Catalysis, Chemical Bond, Conference Paper, Polymerization, Priority Journal, Protein Expression, Protein Synthesis, Rna Translation, Animal, Binding Site, Chemical Structure, Chemistry, Human, Metabolism, Protein Conformation, Review, Models, Molecular, Ribosomal Proteins,
Affiliations:
*** IBB - CNR ***
Weizmann Inst. of Science, Rehovot 76100, Israel
Istituto di Biostrutture e Bioimmagini, C.N.R., I-80134 Napoli, Italy
References:
Not available.
Ribosome's mode of function: Myths, facts and recent results
Ribosomes translate the genetic code into proteins in all living cells with extremely high efficiency, owing to their inherent flexibility and to their spectacular architecture. During the last 6 decades, extensive effort has been made to elucidate the molecular mechanisms associated with their function, and a quantum jump has been made in recent years, once the three dimensional structures of ribosomes and their functional complexes have been determined. These illuminated key issues in ribosome function, confirmed various biochemical, genetic, and medical findings, and revealed mechanistic details beyond previous expectation, thus leading to conceptual revolutions, and turning old myths into actual facts. Copyright © 2008 European Peptide Society and John Wiley & Sons, Ltd.
Ribosome's mode of function: Myths, facts and recent results
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Animal Care, interventional procedures, anesthesia and analgesia of murine models in preclinical imaging
Gargiulo Sara
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Galectins: Structure, function and therapeutic potential inhibitors
Pedone EmiliaMaria
Di Gaetano Sonia
Pirone Luciano
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Peptides of therapeutic interest with antimicrobial and/ or antitumoral activity
Pedone EmiliaMaria
Di Gaetano Sonia
Pirone Luciano
Ribosome's mode of function: Myths, facts and recent results
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Fik-jaskółka M, Mittova V, Motsonelidze C, Vakhania M,
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,
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Agmon I, Amit M, Auerbach T, Bashan A, Baram D, Bartels H,
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Cimino P,
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,
2003 Mar 3;
4(2-3): 171-180.
Impact Factor:
3.992
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Bashan A, Agmon I, Zarivach R, Schluenzen F, Harms J,
Berisio R
, Bartels H, Franceschi F, Auerbach T, Hansen HAS, Kossoy E, Kessler M, Yonath A
*
Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression
(
574 views
)
Mol Cell (ISSN: 1097-2765, 1097-4164)
,
2003 Jan;
11(1): 91-102.
Impact Factor:
16.835
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Yonath A, Bashan A, Zarivach R, Franceschi F, Schluenzen F, Harms J, Albrecht R,
Berisio R
*
Methods Of Growing Crystals Of Free, Antibiotic-Complexed, And Substrate-Complexed Large Ribosomal Subunits, And Methods Of Rational Designing Or Identifying Antibiotics Using Structure Coordinate Data Derived From Such Crystals
(
382 views
)
International Publication Number
,
2003;
N/D: N/D-N/D.
Impact Factor:
4.622
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Esposito L
,
Sica F
, Raia CA, Giordano A, Rossi M,
Mazzarella L
, Zagari A
*
Crystal Structure Of The Alcohol Dehydrogenase From The Hyperthermophilic Archaeon Sulfolobus Solfataricus At 1. 85 Angstrom Resolution
(
746 views
)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic)
,
2002 Apr 26;
318(2): 463-477.
Impact Factor:
5.359
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Romanelli A
, Garella I,
Menchise V
, Iacovino R, Saviano M, Montesarchio D, Didierjean C, Lello PD,
Rossi F
, Benedetti E
*
Crystal-state conformation of Cα, α-dialkylated peptides containing chiral β-homo-residues
(
636 views
)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print)
,
2001;
7(1): 15-26.
Impact Factor:
1.451
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Ciarmiello A,
Del Vecchio S
, Silvestro P, Potena MI, Carriero MV, Thomas R, Botti G, D'Aiuto G,
Salvatore M
Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer
(
677 views
)
Journal Of Clinical Oncology (ISSN: 0732-183x)
,
1998 May;
16(5): 1677-1683.
Impact Factor:
8.228
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50
Records (
50
excluding Abstracts).
Total impact factor:
181.566
(
181.566
excluding Abstracts).
Total 5 year impact factor:
178.025
(
178.025
excluding Abstracts).
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