Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity(454 views) Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M
Department of Experimental Medicine and Biochemical Sciences, University of Roma Tor Vergata, Rome, Italy.
Interuniversity Consortium for the Research on the Chemistry of Metals in Biological Systems, P.za Umberto I 1, I-70100 Bari, Italy
Department of Chemistry, University of Catania, V.le A. Doria, Catania, Italy
Institute of Biostructure and Bioimaging, CNR, Catania, Italy
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Duckeorth, W. C., Bennett, R. G., Hamel, F. G., Insulin degradation: progress and potential (1998) Endocr. Rev., 19, pp. 608-624
Leissring, M. A., Farris, W., Wu, X., Cristodoulou, D. C., Haigis, M. C., Guarente, L., Selkoe, D. J., Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria (2004) Biochem. J., 383, pp. 439-446
Qiu, W. Q., Folstein, M. F., Insulin, insulin-degrading enzyme and amyloid- peptide in Alzheimer's disease: review and hypothesis (2006) Neurobiol. Aging, 27, pp. 190-198
Meigs, J. B., Panhuysen, C. I., Myers, R. H., Wilson, P. W., Cupples, L. A., A genome-wide scan for loci linked to plasma levels of glucose and HbA (1c) in a community-based sample of Caucasian pedigrees: the Framingham offspring study (2002) Diabetes, 53, pp. 833-840
Song, E. -S., Juliano, M. A., Juliano, L., Hersh, L. B., Substrate activation of insulin-degrading enzyme (Insulysin). A potential target for drug development (2003) J. Biol. Chem., 278, pp. 49789-49794
Kuoroichkin, I. V., Insulin-degrading enzyme: embarking on amyloid destruction (2001) Trends Biochem. Sci., 26, pp. 421-425
Davis, K. L., Mohs, R. C., Marin, D. B., Purohit, D. P., Perl, D. P., Lantz, M., Neuropeptide abnormalities in patients with early Alzheimer disease (1999) Arch. Gen. Psychiatry, 56, pp. 981-987
Nemeroff, C. B., The preeminent role of neuropeptide systems in the early pathophysiology of Alzheimer's disease: up with corticotrophin-releasing factor, down with acetylcholine (1999) Arch. Gen. Psychiatry, 56, pp. 991-992
Yowler, B. C., Schengrund, C. L., Botulinum neurotoxin A changes conformation upon binding to ganglioside GT1b (2004) Biochemistry, 43, pp. 9725-9731
Qiu, W. Q., Walsh, D. M., Ye, Z., Vekrellis, K., Zhang, J., Podlisny, M. B., Insulin-degrading enzyme regulates extracellular levels of amyloid -protein by degradation (1998) J. Biol. Chem., 273, pp. 32730-32738
Miller, B. C., Eckman, E. A., Sambamurti, K., Dobbs, N., Chow, K. M., Eckman, C. B., Amyloid- peptide levels in brain are inversely correlated with insulysin activity levels in vivo (2003) Proc. Natl Acad. Sci. USA, 100, pp. 6221-6226
Fields, G. B., Noble, R. L., Solid phase peptide synthesis utilizing 9-fluorenylmethoxy-carbonil amino acids (1990) Int. J. Pept. Protein Res., 35, pp. 161-214
Leissring, M. A., Lu, A., Condron, M. M., Teplow, D. B., Stein, R. L., Farris, W., Selkoe, D. J., Kinetics of amyloid -protein degradation determined by novel fluorescence- and fluorescence polarization-based assays (2003) J. Biol. Chem., 278, pp. 37314-37320
Myszka, D. G., He, X., Dembo, M., Morton, T. A., Goldstein, B., Extending the range of rate constants available from BIACORE: interpreting mass transport-influenced binding data (1998) Biophys. J., 75, pp. 583-594
Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity