Statin: New life for an old drug (365 views)
Pharmacol Res Academic Press, 2008 Jun 23; 350(1-3): 1-2.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.976, 5-year impact factor: 4.483
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84906790576&partnerID=40&md5=0affe368fbeda69452be1e433a8680a5
Keywords: Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor, Antioxidant Activity, Blood Clotting, Bone Metabolism, Cardiovascular Effect, Drug Mechanism, Drug Metabolism, Drug Safety, Editorial, Human, Immunoregulation, Metabolic Regulation, Myopathy, Neuroprotection, Pharmacogenomics, Priority Journal, Sepsis, Conical Intersection, Excited States, Femtosecond, Fluorescence Upconversion, Nucleobases, Pyrimidines, Solvent Effect, Thymine, Uracil,
Affiliations:
*** IBB - CNR ***
Department of Medicine and Surgery, University of Salerno, 84081 Baronissi, Salerno, Italy
Biopharm Research Laboratories, Inc., Tokyo 181-0013, Japan
Laboratoire Francis Perrin, CEA/DSM/DRECAM/SPAM - CNRS URA 2453, CEA/Saclay, F-91191 Gif-sur-Yvette, France
Department of Chemistry, Indian Institute of Technology, Kharagpur, 721 302 WB, India
Dipartimento di Chimica, Universita Federico II, Complesso Universitario Monte S. Angelo, Via Cintia, I-80126 Napoli, Italy
Istituto Biostrutture e Bioimmagini, CNR, V. Mezzocannone 6, 80134 Napoli, Italy
References:
Stossel, T.P., The discovery of statins (2008) Cell, 134 (6), pp. 903-90
Endo, A., The discovery and development of HMG-CoA reductase inhibitors (1992) J Lipid Res, 33 (11), pp. 1569-1582
Endo, A., A historical perspective on the discovery of statins (2010) Proc Jpn Acad ser B: Phys Biol Sci, 86 (5), pp. 484-493
Sirtori, C.R., The pharmacology of statins (2014) Pharmacol Res, 88, pp. 3-11
Mihos, C.G., Pineda, A.M., Santana, O., Cardiovascular effects of statins, beyond lipid-lowering properties (2014) Pharmacol Res, 88, pp. 12-19
Ferri, N., Corsini, A., Clinical evidence of statin therapy in non-dyslipidemic disorders (2014) Pharmacol Res, 88, pp. 20-30
Dobesh, P.P., Olsen, K.M., Statins role in the prevention and treatment of sepsis (2014) Pharmacol Res, 88, pp. 31-40
Ulivieri, C., Baldari, C.T., Statins: From cholesterol-lowering drugs to novel immunomodulators for the treatment of th17-mediated autoimmune diseases (2014) Pharmacol Res, 88, pp. 41-52
Zhang, Y., Bradley, A.D., Wang, D., Reinhardt, R.A., Statins, bone metabolism and treatment of bone catabolic diseases (2014) Pharmacol Res, 88, pp. 53-61
Kassimatis, T., Goldsmith, D.J.A., Statins in chronic kidney disease and kidney transplantation (2014) Pharmacol Res, 88, pp. 62-73
Malfitano, A.M., Marasco, G., Proto, M.C., Laezza, C., Gazzerro, P., Bifulco, M., Statins in neurological disorders: An overview and update (2014) Pharmacol Res, 88, pp. 74-83
Pisanti, S., Picardi, P., Ciaglia, E., D'Alessandro, A., Bifulco, M., Novel prospects of statins as therapeutic agents in cancer (2014) Pharmacol Res, 88, pp. 84-98
Gelissen, I.C., McLachlan, A.J., The pharmacogenomics of statins (2014) Pharmacol Res, 88, pp. 99-106
Norata, G.D., Tibolla, G., Catapano, A.L., Statins and skeletal muscles toxicity: From clinical trials to everyday practice (2014) Pharmacol Res, 88, pp. 107-113
Kohler, B., (2007) Photochem. Photobiol., 83, p. 59
Crespo-Hern ndez, C. E., Cohen, B., Hare, P. M., Kohler, B., (2004) Chem. Rev., 104, p. 1977
Matsika, S., (2004) J. Phys. Chem. A, 108, p. 7584
Matsika, S., (2005) J. Phys. Chem. A, 109, p. 7538
Improta, R., Barone, V., (2004) J. Am. Chem. Soc., 126, p. 14320
Zgierski, M. Z., Patchkovskii, S., Fujiwara, T., Lim, E. C., (2005) J. Phys. Chem. A, 109, p. 9384
Merch n, M., Gonzalez-Luque, R., Climent, T., Serrano-Andres, L., Rodriguez, E., Reguero, M., Pelaez, D., (2006) J. Phys. Chem. B, 110, p. 26471
Hudock, H. R., Levine, B. G., Thompson, A. L., Satzger, H., Townsend, D., Gador, N., Ullrich, S., Martinez, T. J., (2007) J. Phys. Chem. A, 111, p. 8500
Ismail, N., Blancafort, L., Olivucci, M., Kohler, B., Robb, M. A., (2002) J. Am. Chem. Soc., 124, p. 6818
Blancafort, L., Robb, M. A., (2004) J. Phys. Chem. A, 108, p. 10609
Blancafort, L., Cohen, B., Hare, P. M., Kohler, B., Robb, M. A., (2005) J. Phys. Chem. A, 109, p. 4431
Zgierski, M. Z., Alavi, S., (2006) Chem. Phys. Lett., 426, p. 398
Blancafort, L., (2007) Photochem. Photobiol., 83, p. 603
Kistler, K. A., Matsika, S., (2007) J. Phys. Chem. A, 111, p. 2650
Zgierski, M. Z., Fujiwara, T., Kofron, W. G., Lim, E. C., (2007) Phys. Chem. Chem. Phys., 9, p. 3206
Marian, C. M., (2005) J. Chem. Phys., 122, p. 104314
Marian, C., Nolting, D., Weinkauf, R., (2005) Phys. Chem. Chem. Phys., 7, p. 3306
Nielsen, S. B., S lling, T. I., (2005) ChemPhysChem., 6, p. 1276
Perun, S., Sobolewski, A. L., Domcke, W., (2005) Chem. Phys., 313, p. 107
Barbatti, M., Lischka, H., (2007) J. Phys. Chem. A, 111, p. 2852
Chung, W. C., Lan, Z., Ohtsuki, Y., Shimakura, N., Domcke, W., Fujimura, Y., (2007) Phys. Chem. Chem. Phys., 9, p. 2075
Santoro, F., Barone, V., Improta, R., (2007) Proc. Natl. Acad. Sci. USA, 104, p. 9931
Yamazaki, S., Kato, S., (2007) J. Am. Chem. Soc., 129, p. 2901
Gustavsson, T., Banyasz, A., Lazzarotto, E., Markovitsi, D., Scalmani, G., Frisch, M. J., Barone, V., Improta, R., (2006) J. Am. Chem. Soc., 128, p. 607
Gustavsson, T., Sarkar, N., Lazzarotto, E., Markovitsi, D., Barone, V., Improta, R., (2006) J. Phys. Chem. B, 110, p. 12843
Hare, P. M., Crespo-Hern ndez, C. E., Kohler, B., (2006) J. Phys. Chem. B, 110, p. 18641
Markovitsi, D., Talbot, F., Gustavsson, T., Onidas, D., Lazzarotto, E., Marguet, S., (2006) Nature, 441, pp. E7
Onidas, D., Gustavsson, T., Lazzarotto, E., Markovitsi, D., (2007) J. Phys. Chem. B, 111, p. 9644
Buchvarov, I., Wang, Q., Raytchev, M., Trifonov, A., Fiebig, T., (2007) Proc. Natl. Acad. Sci. USA, 104, p. 4794
Gustavsson, T., Sharonov, A., Markovitsi, D., (2002) Chem. Phys. Lett., 351, p. 195
Sharonov, A., Gustavsson, T., Carr, V., Renault, E., Markovitsi, D., (2003) Chem. Phys. Lett., 380, p. 173
Shiang, J. J., Cole, A. G., Sension, R. J., Hang, K., Weng, Y., Trommel, J. S., Marzilli, L. G., Lian, T., (2006) J. Am. Chem. Soc., 128, p. 801
Marks, D., Zhang, H., Glasbeek, M., Borowicz, P., Grabowska, A., (1997) Chem. Phys. Lett., 275, p. 370
Gulbinas, V., Markovitsi, D., Gustavsson, T., Karpicz, R., Veber, M., (2000) J. Phys. Chem. A, 104, p. 5181
Gustavsson, T., Cassara, L., Marguet, S., Gurzadyan, G., Meulen, P. v. d., Pommeret, S., Mialocq, J. -C., (2003) Photochem. Photobiol. Sci., 2, p. 329
Olivucci, M., Lami, A., Santoro, F., (2005) Angew. Chem., Int. Ed., 44, p. 5118
Improta, R., Santoro, F., (2005) J. Chem. Theory Comput., 1, p. 215
F rster, T., Rokos, K., (1967) Chem. Phys. Lett., 1, p. 279
Knight, A. E. W., Selinger, B. K., (1971) Chem. Phys. Lett., 12, p. 419
Pant, D., Levinger, N. E., (1999) J. Phys. Chem. B, 103, p. 7846
Middleton, C. T., Cohen, B., Kohler, B., (2007) J. Phys. Chem. A, 111, p. 10460
Salet, C., Bensasson, R., (1975) Photochem. Photobiol., 22, p. 231
Brown, I. H., Johns, H. E., (1968) Photochem. Photobiol., 8, p. 273
Marian, C. M., Schneider, F., Kleinschmidt, M., Tatchen, J., (2002) Eur. Phys. J. D: Atom., Mol. Opt. Phys., 20, p. 357
Climent, T., Gonzalez-Luque, R., Merchan, M., Serrano-Andres, L., (2007) Chem. Phys. Lett., 441, p. 327
Crespo-Hernández, C.E., Cohen, B., Hare, P.M., Kohler, B., (2004) Chem. Rev., 104, p. 1977
Zgierski, M.Z., Patchkovskii, S., Fujiwara, T., Lim, E.C., (2005) J. Phys. Chem. A, 109, p. 9384
Merchán, M., Gonzalez-Luque, R., Climent, T., Serrano-Andres, L., Rodriguez, E., Reguero, M., Pelaez, D., (2006) J. Phys. Chem. B, 110, p. 26471
Hudock, H.R., Levine, B.G., Thompson, A.L., Satzger, H., Townsend, D., Gador, N., Ullrich, S., Martinez, T.J., (2007) J. Phys. Chem. A, 111, p. 8500
Zgierski, M.Z., Alavi, S., (2006) Chem. Phys. Lett., 426, p. 398
Kistler, K.A., Matsika, S., (2007) J. Phys. Chem. A, 111, p. 2650
Zgierski, M.Z., Fujiwara, T., Kofron, W.G., Lim, E.C., (2007) Phys. Chem. Chem. Phys., 9, p. 3206
Marian, C.M., (2005) J. Chem. Phys., 122, p. 104314
Nielsen, S.B., Sølling, T.I., (2005) ChemPhysChem., 6, p. 1276
Chung, W.C., Lan, Z., Ohtsuki, Y., Shimakura, N., Domcke, W., Fujimura, Y., (2007) Phys. Chem. Chem. Phys., 9, p. 2075
Hare, P.M., Crespo-Hernández, C.E., Kohler, B., (2006) J. Phys. Chem. B, 110, p. 18641
Shiang, J.J., Cole, A.G., Sension, R.J., Hang, K., Weng, Y., Trommel, J.S., Marzilli, L.G., Lian, T., (2006) J. Am. Chem. Soc., 128, p. 801
Förster, T., Rokos, K., (1967) Chem. Phys. Lett., 1, p. 279
Knight, A.E.W., Selinger, B.K., (1971) Chem. Phys. Lett., 12, p. 419
Middleton, C.T., Cohen, B., Kohler, B., (2007) J. Phys. Chem. A, 111, p. 10460
Brown, I.H., Johns, H.E., (1968) Photochem. Photobiol., 8, p. 273
Marian, C.M., Schneider, F., Kleinschmidt, M., Tatchen, J., (2002) Eur. Phys. J. D: Atom., Mol. Opt. Phys., 20, p. 357
Pharmacol Res Academic Press, 2008 Jun 23; 350(1-3): 1-2.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.976, 5-year impact factor: 4.483
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84906790576&partnerID=40&md5=0affe368fbeda69452be1e433a8680a5
Keywords: Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor, Antioxidant Activity, Blood Clotting, Bone Metabolism, Cardiovascular Effect, Drug Mechanism, Drug Metabolism, Drug Safety, Editorial, Human, Immunoregulation, Metabolic Regulation, Myopathy, Neuroprotection, Pharmacogenomics, Priority Journal, Sepsis, Conical Intersection, Excited States, Femtosecond, Fluorescence Upconversion, Nucleobases, Pyrimidines, Solvent Effect, Thymine, Uracil,
Affiliations:
*** IBB - CNR ***
Department of Medicine and Surgery, University of Salerno, 84081 Baronissi, Salerno, Italy
Biopharm Research Laboratories, Inc., Tokyo 181-0013, Japan
Laboratoire Francis Perrin, CEA/DSM/DRECAM/SPAM - CNRS URA 2453, CEA/Saclay, F-91191 Gif-sur-Yvette, France
Department of Chemistry, Indian Institute of Technology, Kharagpur, 721 302 WB, India
Dipartimento di Chimica, Universita Federico II, Complesso Universitario Monte S. Angelo, Via Cintia, I-80126 Napoli, Italy
Istituto Biostrutture e Bioimmagini, CNR, V. Mezzocannone 6, 80134 Napoli, Italy
References:
Stossel, T.P., The discovery of statins (2008) Cell, 134 (6), pp. 903-90
Endo, A., The discovery and development of HMG-CoA reductase inhibitors (1992) J Lipid Res, 33 (11), pp. 1569-1582
Endo, A., A historical perspective on the discovery of statins (2010) Proc Jpn Acad ser B: Phys Biol Sci, 86 (5), pp. 484-493
Sirtori, C.R., The pharmacology of statins (2014) Pharmacol Res, 88, pp. 3-11
Mihos, C.G., Pineda, A.M., Santana, O., Cardiovascular effects of statins, beyond lipid-lowering properties (2014) Pharmacol Res, 88, pp. 12-19
Ferri, N., Corsini, A., Clinical evidence of statin therapy in non-dyslipidemic disorders (2014) Pharmacol Res, 88, pp. 20-30
Dobesh, P.P., Olsen, K.M., Statins role in the prevention and treatment of sepsis (2014) Pharmacol Res, 88, pp. 31-40
Ulivieri, C., Baldari, C.T., Statins: From cholesterol-lowering drugs to novel immunomodulators for the treatment of th17-mediated autoimmune diseases (2014) Pharmacol Res, 88, pp. 41-52
Zhang, Y., Bradley, A.D., Wang, D., Reinhardt, R.A., Statins, bone metabolism and treatment of bone catabolic diseases (2014) Pharmacol Res, 88, pp. 53-61
Kassimatis, T., Goldsmith, D.J.A., Statins in chronic kidney disease and kidney transplantation (2014) Pharmacol Res, 88, pp. 62-73
Malfitano, A.M., Marasco, G., Proto, M.C., Laezza, C., Gazzerro, P., Bifulco, M., Statins in neurological disorders: An overview and update (2014) Pharmacol Res, 88, pp. 74-83
Pisanti, S., Picardi, P., Ciaglia, E., D'Alessandro, A., Bifulco, M., Novel prospects of statins as therapeutic agents in cancer (2014) Pharmacol Res, 88, pp. 84-98
Gelissen, I.C., McLachlan, A.J., The pharmacogenomics of statins (2014) Pharmacol Res, 88, pp. 99-106
Norata, G.D., Tibolla, G., Catapano, A.L., Statins and skeletal muscles toxicity: From clinical trials to everyday practice (2014) Pharmacol Res, 88, pp. 107-113
Kohler, B., (2007) Photochem. Photobiol., 83, p. 59
Crespo-Hern ndez, C. E., Cohen, B., Hare, P. M., Kohler, B., (2004) Chem. Rev., 104, p. 1977
Matsika, S., (2004) J. Phys. Chem. A, 108, p. 7584
Matsika, S., (2005) J. Phys. Chem. A, 109, p. 7538
Improta, R., Barone, V., (2004) J. Am. Chem. Soc., 126, p. 14320
Zgierski, M. Z., Patchkovskii, S., Fujiwara, T., Lim, E. C., (2005) J. Phys. Chem. A, 109, p. 9384
Merch n, M., Gonzalez-Luque, R., Climent, T., Serrano-Andres, L., Rodriguez, E., Reguero, M., Pelaez, D., (2006) J. Phys. Chem. B, 110, p. 26471
Hudock, H. R., Levine, B. G., Thompson, A. L., Satzger, H., Townsend, D., Gador, N., Ullrich, S., Martinez, T. J., (2007) J. Phys. Chem. A, 111, p. 8500
Ismail, N., Blancafort, L., Olivucci, M., Kohler, B., Robb, M. A., (2002) J. Am. Chem. Soc., 124, p. 6818
Blancafort, L., Robb, M. A., (2004) J. Phys. Chem. A, 108, p. 10609
Blancafort, L., Cohen, B., Hare, P. M., Kohler, B., Robb, M. A., (2005) J. Phys. Chem. A, 109, p. 4431
Zgierski, M. Z., Alavi, S., (2006) Chem. Phys. Lett., 426, p. 398
Blancafort, L., (2007) Photochem. Photobiol., 83, p. 603
Kistler, K. A., Matsika, S., (2007) J. Phys. Chem. A, 111, p. 2650
Zgierski, M. Z., Fujiwara, T., Kofron, W. G., Lim, E. C., (2007) Phys. Chem. Chem. Phys., 9, p. 3206
Marian, C. M., (2005) J. Chem. Phys., 122, p. 104314
Marian, C., Nolting, D., Weinkauf, R., (2005) Phys. Chem. Chem. Phys., 7, p. 3306
Nielsen, S. B., S lling, T. I., (2005) ChemPhysChem., 6, p. 1276
Perun, S., Sobolewski, A. L., Domcke, W., (2005) Chem. Phys., 313, p. 107
Barbatti, M., Lischka, H., (2007) J. Phys. Chem. A, 111, p. 2852
Chung, W. C., Lan, Z., Ohtsuki, Y., Shimakura, N., Domcke, W., Fujimura, Y., (2007) Phys. Chem. Chem. Phys., 9, p. 2075
Santoro, F., Barone, V., Improta, R., (2007) Proc. Natl. Acad. Sci. USA, 104, p. 9931
Yamazaki, S., Kato, S., (2007) J. Am. Chem. Soc., 129, p. 2901
Gustavsson, T., Banyasz, A., Lazzarotto, E., Markovitsi, D., Scalmani, G., Frisch, M. J., Barone, V., Improta, R., (2006) J. Am. Chem. Soc., 128, p. 607
Gustavsson, T., Sarkar, N., Lazzarotto, E., Markovitsi, D., Barone, V., Improta, R., (2006) J. Phys. Chem. B, 110, p. 12843
Hare, P. M., Crespo-Hern ndez, C. E., Kohler, B., (2006) J. Phys. Chem. B, 110, p. 18641
Markovitsi, D., Talbot, F., Gustavsson, T., Onidas, D., Lazzarotto, E., Marguet, S., (2006) Nature, 441, pp. E7
Onidas, D., Gustavsson, T., Lazzarotto, E., Markovitsi, D., (2007) J. Phys. Chem. B, 111, p. 9644
Buchvarov, I., Wang, Q., Raytchev, M., Trifonov, A., Fiebig, T., (2007) Proc. Natl. Acad. Sci. USA, 104, p. 4794
Gustavsson, T., Sharonov, A., Markovitsi, D., (2002) Chem. Phys. Lett., 351, p. 195
Sharonov, A., Gustavsson, T., Carr, V., Renault, E., Markovitsi, D., (2003) Chem. Phys. Lett., 380, p. 173
Shiang, J. J., Cole, A. G., Sension, R. J., Hang, K., Weng, Y., Trommel, J. S., Marzilli, L. G., Lian, T., (2006) J. Am. Chem. Soc., 128, p. 801
Marks, D., Zhang, H., Glasbeek, M., Borowicz, P., Grabowska, A., (1997) Chem. Phys. Lett., 275, p. 370
Gulbinas, V., Markovitsi, D., Gustavsson, T., Karpicz, R., Veber, M., (2000) J. Phys. Chem. A, 104, p. 5181
Gustavsson, T., Cassara, L., Marguet, S., Gurzadyan, G., Meulen, P. v. d., Pommeret, S., Mialocq, J. -C., (2003) Photochem. Photobiol. Sci., 2, p. 329
Olivucci, M., Lami, A., Santoro, F., (2005) Angew. Chem., Int. Ed., 44, p. 5118
Improta, R., Santoro, F., (2005) J. Chem. Theory Comput., 1, p. 215
F rster, T., Rokos, K., (1967) Chem. Phys. Lett., 1, p. 279
Knight, A. E. W., Selinger, B. K., (1971) Chem. Phys. Lett., 12, p. 419
Pant, D., Levinger, N. E., (1999) J. Phys. Chem. B, 103, p. 7846
Middleton, C. T., Cohen, B., Kohler, B., (2007) J. Phys. Chem. A, 111, p. 10460
Salet, C., Bensasson, R., (1975) Photochem. Photobiol., 22, p. 231
Brown, I. H., Johns, H. E., (1968) Photochem. Photobiol., 8, p. 273
Marian, C. M., Schneider, F., Kleinschmidt, M., Tatchen, J., (2002) Eur. Phys. J. D: Atom., Mol. Opt. Phys., 20, p. 357
Climent, T., Gonzalez-Luque, R., Merchan, M., Serrano-Andres, L., (2007) Chem. Phys. Lett., 441, p. 327
Crespo-Hernández, C.E., Cohen, B., Hare, P.M., Kohler, B., (2004) Chem. Rev., 104, p. 1977
Zgierski, M.Z., Patchkovskii, S., Fujiwara, T., Lim, E.C., (2005) J. Phys. Chem. A, 109, p. 9384
Merchán, M., Gonzalez-Luque, R., Climent, T., Serrano-Andres, L., Rodriguez, E., Reguero, M., Pelaez, D., (2006) J. Phys. Chem. B, 110, p. 26471
Hudock, H.R., Levine, B.G., Thompson, A.L., Satzger, H., Townsend, D., Gador, N., Ullrich, S., Martinez, T.J., (2007) J. Phys. Chem. A, 111, p. 8500
Zgierski, M.Z., Alavi, S., (2006) Chem. Phys. Lett., 426, p. 398
Kistler, K.A., Matsika, S., (2007) J. Phys. Chem. A, 111, p. 2650
Zgierski, M.Z., Fujiwara, T., Kofron, W.G., Lim, E.C., (2007) Phys. Chem. Chem. Phys., 9, p. 3206
Marian, C.M., (2005) J. Chem. Phys., 122, p. 104314
Nielsen, S.B., Sølling, T.I., (2005) ChemPhysChem., 6, p. 1276
Chung, W.C., Lan, Z., Ohtsuki, Y., Shimakura, N., Domcke, W., Fujimura, Y., (2007) Phys. Chem. Chem. Phys., 9, p. 2075
Hare, P.M., Crespo-Hernández, C.E., Kohler, B., (2006) J. Phys. Chem. B, 110, p. 18641
Shiang, J.J., Cole, A.G., Sension, R.J., Hang, K., Weng, Y., Trommel, J.S., Marzilli, L.G., Lian, T., (2006) J. Am. Chem. Soc., 128, p. 801
Förster, T., Rokos, K., (1967) Chem. Phys. Lett., 1, p. 279
Knight, A.E.W., Selinger, B.K., (1971) Chem. Phys. Lett., 12, p. 419
Middleton, C.T., Cohen, B., Kohler, B., (2007) J. Phys. Chem. A, 111, p. 10460
Brown, I.H., Johns, H.E., (1968) Photochem. Photobiol., 8, p. 273
Marian, C.M., Schneider, F., Kleinschmidt, M., Tatchen, J., (2002) Eur. Phys. J. D: Atom., Mol. Opt. Phys., 20, p. 357
Statin: New life for an old drug
The excited state lifetimes of uracil, thymine and 5-fluorouracil have been measured using femtosecond UV fluorescence upconversion in various protic and aprotic polar solvents. The fastest decays are observed in acetonitrile and the slowest in aqueous solution while those observed in alcohols are intermediate. No direct correlation with macroscopic solvent parameters such as polarity or viscosity is found, but hydrogen bonding is one key factor affecting the fluorescence decay. It is proposed that the solvent modulates the relative energy of two close-lying electronically excited states, the bright pi pi* and the dark pi pi* states. This relative energy gap controls the non-radiative relaxation of the pi pi* state through a conical intersection close to the Franck-Condon region competing with the ultrafast internal conversion to the ground state. In addition, an inverse isotope effect is observed in D2O where the decays are faster than in H2O. (C) 2008 Elsevier B.V. All rights reserved.
The excited state lifetimes of uracil, thymine and 5-fluorouracil have been measured using femtosecond UV fluorescence upconversion in various protic and aprotic polar solvents. The fastest decays are observed in acetonitrile and the slowest in aqueous solution while those observed in alcohols are intermediate. No direct correlation with macroscopic solvent parameters such as polarity or viscosity is found, but hydrogen bonding is one key factor affecting the fluorescence decay. It is proposed that the solvent modulates the relative energy of two close-lying electronically excited states, the bright pi pi* and the dark pi pi* states. This relative energy gap controls the non-radiative relaxation of the pi pi* state through a conical intersection close to the Franck-Condon region competing with the ultrafast internal conversion to the ground state. In addition, an inverse isotope effect is observed in D2O where the decays are faster than in H2O. (C) 2008 Elsevier B.V. All rights reserved.
Statin: New life for an old drug
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Statin: New life for an old drug
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J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2014; 29(4): 500-504.
Impact Factor: 2.332
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (510 views)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
View Export to BibTeX Export to EndNote
Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (3606 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (550 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (445 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
View Export to BibTeX Export to EndNote
Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
View Export to BibTeX Export to EndNote
Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (377 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
View Export to BibTeX Export to EndNote
Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
View Export to BibTeX Export to EndNote
Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (554 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
View Export to BibTeX Export to EndNote
Coppola G, Fortunato D, Auricchio G, Mainolfi C, Operto FF, Signoriello G, Pascotto A, Salvatore M
* Bone mineral density in children, adolescents, and young adults with epilepsy (372 views)
Epilepsia (ISSN: 1528-1167, 0013-9580), 2009 Sep; 50(9): 2140-2146.
Impact Factor: 4.052
View Export to BibTeX Export to EndNote
Cittadini A, Saldamarco L, Marra AM, Arcopinto M, Carlomagno G, Imbriaco M, Del Forno D, Vigorito C, Merola B, Oliviero U, Fazio S, Sacca L
* Growth Hormone Deficiency in Patients with Chronic Heart Failure and Beneficial Effects of Its Correction (610 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2009 Sep; 94(9): 3329-3336.
Impact Factor: 6.202
View Export to BibTeX Export to EndNote
De Simone G, Supuran CT
* Drug Design of Antiobesity Carbonic Anhydrase Inhibitors (332 views)
Drug Des Of Zinc Enzyme Inhibitors (ISSN: 9780-4702, 9780-470275009), 2009; 66(DECEMBERSPEC.I): 241-254.
Impact Factor: 1.156
View Export to BibTeX Export to EndNote
Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (449 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Vitiello M, Galdiero S, D'Isanto M, D'Amico M, Di Filippo C, Cantisani M, Galdiero M, Pedone C
* Pathophysiological changes of gram-negative bacterial infection can be reproduced by a synthetic peptide mimicking loop L7 sequence of Haemophilus influenzae porin (323 views)
Microbes And Infection / Institut Pasteur (ISSN: 1286-4579), 2008 May; 10(6): 657-663.
Impact Factor: 2.801
View Export to BibTeX Export to EndNote
Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (444 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
View Export to BibTeX Export to EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (753 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
View Export to BibTeX Export to EndNote
Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (370 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
View Export to BibTeX Export to EndNote
Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
* Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity (254 views)
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.
Impact Factor: 1.713
View Export to BibTeX Export to EndNote
Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (669 views)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
View Export to BibTeX Export to EndNote
Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (348 views)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
View Export to BibTeX Export to EndNote
Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (437 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
View Export to BibTeX Export to EndNote
Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
* Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (385 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2003; (23): 4406-4415.
Impact Factor: 2.908
View Export to BibTeX Export to EndNote
Borrelli RC, Fogliano V, Monti SM, Ames JM
* Characterization of melanoidins from a glucose-glycine model system (243 views)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(3): 210-215.
Impact Factor: 1.021
View Export to BibTeX Export to EndNote
Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (883 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
View Export to BibTeX Export to EndNote
Colao A, Marzullo P, Ferone D, Spinelli L, Cuocolo A, Bonaduce D, Salvatore M, Boerlin V, Lancranjan I, Lombardi G
Cardiovascular effects of depot long-acting somatostatin analog sandostatin LAR in acromegaly (428 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Sep; 85(9): 3132-3140.
Impact Factor: 5.447
View Export to BibTeX Export to EndNote
Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (564 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
View Export to BibTeX Export to EndNote
Fogliano V, Ritieni A, Monti SM, Gallo M, Della Medaglia D, Ambrosino ML, Sacchi R
Antioxidant activity of virgin olive oil phenolic compounds in a micellar system (301 views)
Journal Of The Science Of Food And Agriculture (ISSN: 0022-5142), 1999 Oct; 79(13): 1803-1808.
Impact Factor: 1.097
View Export to BibTeX Export to EndNote
De Simone G, Lombardi A, Galdiero S, Nastri F, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V
Hirunorms Are True Hirudin Mimetics. The Crystal Structure Of Human Alpha-Thrombin-Hirunorm V Complex (520 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 1998 Feb; 7(2): 243-253.
Impact Factor: 4.44
View Export to BibTeX Export to EndNote
Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (685 views)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
View Export to BibTeX Export to EndNote
Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (366 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
View Export to BibTeX Export to EndNote
* Trifluoroacetylated tyrosine-rich D-tetrapeptides have potent antioxidant activity (401 views)
Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 2017 Mar; 89: 50-59.
Impact Factor: 2.851
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Marcucci G, Cianferotti L, Beck-Peccoz P, Capezzone M, Cetani F, Colao A, Davì MV, Degli Uberti E, Del Prato S, Elisei R, Faggiano A, Ferone D, Foresta C, Fugazzola L, Ghigo E, Giacchetti G, Giorgino F, Lenzi A, Malandrino P, Mannelli M, Marcocci C, Masi L, Pacini F, Opocher G, Radicioni A, Tonacchera M, Vigneri R, Zatelli MC, Brandi ML
* Rare diseases in clinical endocrinology: A taxonomic classification system (778 views)
J Endocrinol Invest (ISSN: 1720-8386, 0391-4097, 1720-8386electronic), 2015; 38(2): 193-259.
Impact Factor: 1.994
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Dathan NA, Alterio V, Troiano E, Vullo D, Ludwig M, De Simone G, Supuran CT, Monti SM
* Biochemical Characterization Of The Chloroplastic β-Carbonic Anhydrase From Flaveria Bidentis (l. ) "kuntze" (464 views)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2014; 29(4): 500-504.
Impact Factor: 2.332
View Export to BibTeX Export to EndNote
Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (510 views)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
View Export to BibTeX Export to EndNote
Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
View Export to BibTeX Export to EndNote
Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (3606 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
View Export to BibTeX Export to EndNote
De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (550 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
View Export to BibTeX Export to EndNote
Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (445 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
View Export to BibTeX Export to EndNote
Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
View Export to BibTeX Export to EndNote
Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (377 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
View Export to BibTeX Export to EndNote
Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
View Export to BibTeX Export to EndNote
Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (554 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
View Export to BibTeX Export to EndNote
Coppola G, Fortunato D, Auricchio G, Mainolfi C, Operto FF, Signoriello G, Pascotto A, Salvatore M
* Bone mineral density in children, adolescents, and young adults with epilepsy (372 views)
Epilepsia (ISSN: 1528-1167, 0013-9580), 2009 Sep; 50(9): 2140-2146.
Impact Factor: 4.052
View Export to BibTeX Export to EndNote
Cittadini A, Saldamarco L, Marra AM, Arcopinto M, Carlomagno G, Imbriaco M, Del Forno D, Vigorito C, Merola B, Oliviero U, Fazio S, Sacca L
* Growth Hormone Deficiency in Patients with Chronic Heart Failure and Beneficial Effects of Its Correction (610 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2009 Sep; 94(9): 3329-3336.
Impact Factor: 6.202
View Export to BibTeX Export to EndNote
De Simone G, Supuran CT
* Drug Design of Antiobesity Carbonic Anhydrase Inhibitors (332 views)
Drug Des Of Zinc Enzyme Inhibitors (ISSN: 9780-4702, 9780-470275009), 2009; 66(DECEMBERSPEC.I): 241-254.
Impact Factor: 1.156
View Export to BibTeX Export to EndNote
Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (449 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Vitiello M, Galdiero S, D'Isanto M, D'Amico M, Di Filippo C, Cantisani M, Galdiero M, Pedone C
* Pathophysiological changes of gram-negative bacterial infection can be reproduced by a synthetic peptide mimicking loop L7 sequence of Haemophilus influenzae porin (323 views)
Microbes And Infection / Institut Pasteur (ISSN: 1286-4579), 2008 May; 10(6): 657-663.
Impact Factor: 2.801
View Export to BibTeX Export to EndNote
Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (444 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
View Export to BibTeX Export to EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (753 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
View Export to BibTeX Export to EndNote
Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (370 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
View Export to BibTeX Export to EndNote
Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
* Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity (254 views)
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.
Impact Factor: 1.713
View Export to BibTeX Export to EndNote
Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (669 views)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
View Export to BibTeX Export to EndNote
Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (348 views)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
View Export to BibTeX Export to EndNote
Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (437 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
View Export to BibTeX Export to EndNote
Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
* Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (385 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2003; (23): 4406-4415.
Impact Factor: 2.908
View Export to BibTeX Export to EndNote
Borrelli RC, Fogliano V, Monti SM, Ames JM
* Characterization of melanoidins from a glucose-glycine model system (243 views)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(3): 210-215.
Impact Factor: 1.021
View Export to BibTeX Export to EndNote
Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (883 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
View Export to BibTeX Export to EndNote
Colao A, Marzullo P, Ferone D, Spinelli L, Cuocolo A, Bonaduce D, Salvatore M, Boerlin V, Lancranjan I, Lombardi G
Cardiovascular effects of depot long-acting somatostatin analog sandostatin LAR in acromegaly (428 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2000 Sep; 85(9): 3132-3140.
Impact Factor: 5.447
View Export to BibTeX Export to EndNote
Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (564 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
View Export to BibTeX Export to EndNote
Fogliano V, Ritieni A, Monti SM, Gallo M, Della Medaglia D, Ambrosino ML, Sacchi R
Antioxidant activity of virgin olive oil phenolic compounds in a micellar system (301 views)
Journal Of The Science Of Food And Agriculture (ISSN: 0022-5142), 1999 Oct; 79(13): 1803-1808.
Impact Factor: 1.097
View Export to BibTeX Export to EndNote
De Simone G, Lombardi A, Galdiero S, Nastri F, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V
Hirunorms Are True Hirudin Mimetics. The Crystal Structure Of Human Alpha-Thrombin-Hirunorm V Complex (520 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 1998 Feb; 7(2): 243-253.
Impact Factor: 4.44
View Export to BibTeX Export to EndNote
Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (685 views)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
View Export to BibTeX Export to EndNote
Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (366 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
View Export to BibTeX Export to EndNote
33 Records (33 excluding Abstracts).
Total impact factor: 124.152 (124.152 excluding Abstracts).
Total 5 year impact factor: 132.963 (132.963 excluding Abstracts).
Total impact factor: 124.152 (124.152 excluding Abstracts).
Total 5 year impact factor: 132.963 (132.963 excluding Abstracts).
365 views. Last view on Saturday 14 January 2023, 19:14:19
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