Comparison of Myocardial Perfusion (82)Rb PET Performed with CT- and Transmission CT-Based Attenuation Correction(562 views) Slomka PJ, Le Meunier L, Hayes SW, Acampa W, Oba M, Haemer GG, Berman DS, Germano G
Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States
Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
Department of Imaging, Cedars-Sinai Medical Center, #A047, 8700 Beverly Blvd., Los Angeles, CA 90048, United States
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Santana, C. A., Folks, R. D., Garcia, E. V., Quantitative 82Rb PET/CT: Development and Validation of Myocardial Perfusion Database (2007) J Nucl Med, 48, pp. 1122-1128
van Dalen, J. A., Visser, E. P., Vogel, W. V., Corstens, F. H., Oyen, W. J., Impact of Ge-68/Ga-68-based versus CT-based attenuation correction on PET (2007) Med Phys, 34, pp. 889-897
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Cook, R. A., Carnes, G., Lee, T. Y., Wells, R. G., Respiration-averaged CT for attenuation correction in canine cardiac PET/CT (2007) J Nucl Med, 48, pp. 811-818
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Comparison of Myocardial Perfusion (82)Rb PET Performed with CT- and Transmission CT-Based Attenuation Correction
CT-based attenuation correction (AC) for myocardial perfusion PET studies is challenging because of respiratory motion. Our study aimedto compare the transmission CT (TCT)-based and CT-based AC for myocardial perfusion PET/CT images with a direct semi-quantitative approach comparing differences in segmental count distribution. Methods: Stress and rest (82)Rb PET scans from 54 consecutive patients acquired on a PET/CT scanner with dual CT-based and TCT-based AC were considered. TCT- and CT-based AC images were automatically registered to each other, and direct voxel-based and American Heart Association segment-based estimation of positive and negative changes between these scans was performed. Additionally, visual quality control (QC) of CT map alignment with PET emission data was performed by 2 expert observers, and studies with significant (>= 5 mm) misalignment were reprocessed with corrected CT alignment. Results: We used the 17-segment American Heart Association model for TCT-to-CT regional change analysis in all patients and found that 4 segments on rest and 4 segments on stress scans differed more than 3% between CT- and TCT-corrected images for studies without significant misalignments (
Comparison of Myocardial Perfusion (82)Rb PET Performed with CT- and Transmission CT-Based Attenuation Correction
Aloj L, Aurilio M, Rinaldi V, D'Ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R, Von Guggenberg E, Joosten L, Sosabowski JK, Breeman WA, De Blois E, Koelewijn S, Melis M, Waser B, Beetschen K, Reubi JC, De Jong M * The EEE project(449 views) Proc Int Cosm Ray Conf Icrc Universidad Nacional Autonoma De Mexico, 2007; 5(HEPART2): 977-980. Impact Factor:0 ViewExport to BibTeXExport to EndNote