Kinetic investigation of porphyrin interaction with chiral templates reveals unexpected features of the induction and self-propagation mechanism of chiral memory
Kinetic investigation of porphyrin interaction with chiral templates reveals unexpected features of the induction and self-propagation mechanism of chiral memory(405 views) Lauceri R, Fasciglione G, D'Urso A, Marini S, Purrello R, Coletta M
Istituto di Biostrutture e Bioimmagini, CNR, Sezione di Catania, Viale A. Doria 6, 95125 Catania, Italy.
References: Bellacchio, E., Lauceri, R., Gurrieri, S., Monsù Scolaro, L., Romeo, A., Purrello, R., (1998) J. Am. Chem. Soc, 120, p. 1235
Purrello, R., Raudino, A., Monsù Scolaro, L., Loisi, A., Bellacchio, E., Lauceri, R., (2000) J. Phys. Chem. A, 104, p. 10900
Lauceri, R., Raudino, A., Monsù Scolaro, L., Micali, N., Purrello, R., (2002) J. Am. Chem. Soc, 124, p. 894
As already reported,1-3 CuT4-TPPS interactions do not lead to CD signals because their assemblies are not chiral in the absence of a chiral matrixIn this experimental approach light scattering (due to porphyrin aggregation and causing baseline increases, see Supporting Information) is competing with absorption and must be carefully consideredSteinbach, P.J., (1991) Biochemistry, 30, p. 3988
Kinetic profiles for L- or D-PheA are the sameInteractions of one porphyrin with PheA do not lead to an ICD. The absence of a CD signal can be due either to the absence of chiral species or (more likely) to the formation of species having very weak CD signalsThis fast cooperative event is accompanied by an increase of light scattering (data not shown) which reflects porphyrin aggregation. This impairs the observation of the typical hypochromicity associated to aggregationThe observation that β value is always oscillating between 3.0 and 4.0 suggests structural organization of at least four moleculesAbraham, F.F., (1974) Homogeneous Nucleation Theory, , Academic Press: New York
Likely occurring within the first second after the mixingThis is suggested by the decreasing intensity of the signal upon addition of the latter porphyrinUR - http://www.scopus.com/inward/record.url?eid=2-s2.0-49449085692&partnerID=40&md5=cc01ba73e199b21e22ef046122de2d8c
Kinetic investigation of porphyrin interaction with chiral templates reveals unexpected features of the induction and self-propagation mechanism of chiral memory
Kinetic investigation of porphyrin interaction with chiral templates reveals unexpected features of the induction and self-propagation mechanism of chiral memory
Kinetic investigation of porphyrin interaction with chiral templates reveals unexpected features of the induction and self-propagation mechanism of chiral memory
Kállay C, Dávid A, Timári S, Nagy EM, Sanna D, Garribba E, Micera G, De Bona P, Pappalardo G, Rizzarelli E, Sóvágó I * Copper(II) complexes of rat amylin fragments(357 views) Dalton T (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2011 Oct 14; 40(38): 9711-9721. Impact Factor:3.838 ViewExport to BibTeXExport to EndNote