Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin(393 views) Cigliano L, D'Andrea LD, Maresca B, Serino M, Carlucci A, Salvatore A, Spagnuolo MS, Scigliuolo G, Pedone C, Abrescia P
Keywords: Apoa-I Zaragoza, Apoa-I Zavalla, High-Density Lipoprotein, Lecithin-Cholesterol Acyltransferase, Peptides, Reverse Cholesterol Transport, Apolipoprotein A1, Haptoglobin, High Density Lipoprotein Cholesterol, Phosphatidylcholine Sterol Acyltransferase, Amino Acid Substitution, Article, Binding Assay, Binding Site, Correlation Analysis, Enzyme Activity, Enzyme Regulation, Human, Point Mutation, Priority Journal, Protein Binding, Protein Protein Interaction, Protein Variant, Amino Acid Sequence, Competitive, Molecular Sequence Data, Phosphatidylcholine-Sterol O-Acyltransferase,
Affiliations: *** IBB - CNR ***
Dipartimento delle Scienze Biologiche, Universita di Napoli Federico II, I-80134 Napoli, Italy.
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, I-80134 Napoli, Italy
Dipartimento di Patologia Sistematica, Sezione di Dermatologia, Università di Napoli Federico II, I-80131 Napoli, Italy
Istituto Per Il Sistema Produzione Animale in Ambiente Mediterraneo, Consiglio Nazionale Delle Ricerche, I-80147 Napoli, Italy
Istituto di Genetica e Biofisica 'A. Buzzati Traverso', Consiglio Nazionale Delle Ricerche, I-80131 Napoli, Italy
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Ajees, A.A., Anantharamaiah, G.M., Mishra, V.K., Hussain, M.M., Murthy, H.M., Crystal structure of human apolipoprotein A-I: Insights into its protective effect against cardiovascular diseases (2006) Proc. Natl. Acad. Sci. USA, 103, pp. 2126-2131
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Chan, W.D., White, P.D., (2000) Fmoc Solid Phase Peptide Synthesis, , New York, USA: Academic Press
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Zannis, V.I., Koukos, G., Drosatos, K., Vezeridis, A., Zanni, E.E., Kypreos, K.E., Chroni, A., Discrete roles of apoAI and apoE in the biogenesis of HDL species: Lessons learned from gene transfer studies in different mouse models (2008) Ann. Med, 40 (SUPPL. 1), pp. 14-28
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Ansell, B. J., Navab, M., Hama, S., Kamranpour, N., Fonarow, G., Hough, G., Rahmani, S., Fogelman, A. M., Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment (2003) Circulation, 108, pp. 2751-2756
Ajees, A. A., Anantharamaiah, G. M., Mishra, V. K., Hussain, M. M., Murthy, H. M., Crystal structure of human apolipoprotein A-I: Insights into its protective effect against cardiovascular diseases (2006) Proc. Natl. Acad. Sci. USA, 103, pp. 2126-2131
Borhani, D. W., Rogers, D. P., Engler, J. A., Brouillette, C. G., Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation (1997) Proc. Natl. Acad. Sci. USA, 94, pp. 12291-12296
Chan, W. D., White, P. D., (2000) Fmoc Solid Phase Peptide Synthesis, , New York, USA: Academic Press
Chen, C. -H., Albers, J. J., Characterization of proteoliposomes containing apoprotein A-I: A new substrate for the measurement of lecithin: cholesterol acyltransferase activity (1982) J. Lipid Res, 23, pp. 680-691
Davidson, V. S., Thompson, T. B., The structure of apolipoprotein A-I in high density lipoproteins (2007) J. Biol. Chem, 282, pp. 22249-22253
Hovingh, G. K., Brownlie, A., Bisoendial, R. J., Dube, M. P., Levels, J. H., Petersen, W., Dullaart, R. P., de Groot, E., A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease (2004) J. Am. Coll. Cardiol, 44, pp. 1429-1435
Langlois, M. R., Delanghe, J. R., Biological and clinical significance of haptoglobin polymorphism in humans (1996) Clin. Chem, 42, pp. 1589-1600
Lindholm, E. M., Bielicki, J. K., Curtiss, L. K., Rubin, E. M., Forte, T. M., Deletion of amino acids Glu146 to Arg160 in human apolipoprotein A-I (apoA-I Seattle) alters lecithin: Cholesterol acyltransferase activity and recruitment of cell phospholipid (1998) Biochemistry, 37, pp. 4863-4868
Miettinen, H. E., Gylling, H., Miettinen, T. A., Viikari, J., Paulin, L., Kontula, K., Apolipoprotein A-IFin. Dominantly inherited hypoalphalipoproteinemia due to a single base substitution in the apolipoprotein A-I gene (1997) Arterioscler. Thromb. Vasc. Biol, 17, pp. 83-90
Palgunachari, M. N., Mishra, V. K., Lund-Katz, S., Phillips, M. C., Adeyeye, S. O., Alluri, S., Anantharamaiah, G. M., Segrest, J. P., Only the two end helixes of eight tandem amphipathic helical domains of human apo A-I have significant lipid affinity. Implications for HDL assembly (1996) Arterioscler. Thromb. Vasc. Biol, 16, pp. 328-338
Rader, D. J., High-density lipoproteins and atherosclerosis (2002) Am. J. Cardiol, 90, pp. 62i-70i
Sorci-Thomas, M. G., Thomas, M. J., The effects of altered apolipoproteinA-I structure on plasma HDL concentration (2002) Trends Cardiovasc. Med, 12, pp. 121-128
Spagnuolo, M. S., Cigliano, L., Abrescia, P., The binding of haptoglobin to apolipoprotein A-I: Influence of hemoglobin and concanavalin A (2003) Biol. Chem, 384, pp. 1593-1596
Zannis, V. I., Chroni, A., Krieger, M., Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL (2006) J. Mol. Med, 84, pp. 276-294
Zannis, V. I., Koukos, G., Drosatos, K., Vezeridis, A., Zanni, E. E., Kypreos, K. E., Chroni, A., Discrete roles of apoAI and apoE in the biogenesis of HDL species: Lessons learned from gene transfer studies in different mouse models (2008) Ann. Med, 40 (SUPPL. 1), pp. 14-28
Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin