New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (444 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 2.882, 5-year impact factor: 3.114
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-38949163284&partnerID=40&md5=f04150fd1c1d1b248f754fc7876883e3
Keywords: β-Cyclodextrin, Anserine, Antioxidant Activity, Carnosine, Homocarnosine, Neurodegeneration, Aminoacylhistidine Dipeptidase, Beta Cyclodextrin, Copper Ion, Dipeptide Derivative, Enzyme, Glycoside, Malonaldehyde, Unclassified Drug, Animal Tissue, Article, Enzyme Activity, Hydrolysis, Mass Spectrometry, Nonhuman, Proton Nuclear Magnetic Resonance, ß-Cyclodextrin,
Affiliations:
*** IBB - CNR ***
Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
CNR Institute of Biostructure and Bioimaging, Viale A. Doria 6, 95125 Catania, Italy
Institute of Biochemistry and Clinical Biochemistry, Catholic University of Rome, Largo F. Vito 1, 00164 Rome, Italy
References:
Neidle, A., Kandera, J., (1974) Brain Res., 80, pp. 359-36
Sobue, K., Konishi, H., Nakajima, T., (1975) J. Neurochem., 24, pp. 1261-1262
Bonfanti, L., Peretto, P., De Marchis, S., Fasolo, A., (1999) Prog. Neurobiol., 59, pp. 333-353
Nadi, N.S., Hirsch, J.D., Margolis, F.L., (1980) J. Neurochem., 34, pp. 138-146
Baslow, M.H., (2002) Neurochem. Int., 40, pp. 295-300
Baslow, M.H., (2003) Neurochem. Res., 28, pp. 941-953
Baslow, M.H., Dyakin, V.V., Nowak, K.L., Hungund, B.L., Guilfoyle, D.N., (2005) J. Mol. Neurosci., 26, pp. 1-15
Baslow, M.H., Suckow, R.F., Berg, M.J., Marks, N., Saito, M., Bhakoo, K.K., (2001) J. Mol. Neurosci., 17, pp. 351-359
Boldyrev, A.A., Dupin, A.M., Pindel, E.V., Severin, S.E., (1988) Comp. Biochem. Physiol., B, 89, pp. 245-250
Boldyrev, A.A., Johnson, P., Wei, Y., Tan, Y., Carpenter, D.O., (1999) Neurosci. Lett., 263, pp. 169-172
Kohen, R., Yamamoto, Y., Cundy, K.C., Ames, B.N., (1988) Proc. Natl. Acad. Sci. U.S.A., 85, pp. 3175-3179
Cuzzocrea, S., Genovese, T., Failla, M., Vecchio, G., Fruciano, M., Mazzon, E., Di Paola, R., Vancheri, C., (2007) Am. J. Physiol., 292, pp. L1095-L1104
Abe, H., (2000) Biochemistry (Mosc.), 65, pp. 757-765
Hipkiss, A.R., Brownson, C., Bertani, M.F., Ruiz, E., Ferro, A., (2002) Ann. N.Y. Acad. Sci., 959, pp. 285-294
Seidler, N.W., Yeargans, G.S., Morgan, T.G., (2004) Arch. Biochem. Biophys., 427, pp. 110-115
Boldyrev, A., Koudinov, A., Berezov, T., Carpenter, D.O., (2004) J. Alzheimers Dis., 6, pp. 633-638. , discussion 673-681
Dukic-Stefanovic, S., Schinzel, R., Riederer, P., Munch, G., (2001) Biogerontology, 2, pp. 19-34
Kang, J.H., Kim, K.S., (2003) Mol. Cell, 15, pp. 87-93
Munch, G., Mayer, S., Michaelis, J., Hipkiss, A.R., Riederer, P., Muller, R., Neumann, A., Cunningham, A.M., (1997) Biochim. Biophys. Acta, 1360, pp. 17-29
Jackson, M.C., Kucera, C.M., Lenney, J.F., (1991) Clin. Chim. Acta, 196, pp. 193-205
Lenney, J.F., George, R.P., Weiss, A.M., Kucera, C.M., Chan, P.W., Rinzler, G.S., (1982) Clin. Chim. Acta, 123, pp. 221-231
Teufel, M., Saudek, V., Ledig, J.-P., Bernhardt, A., Boularand, S., Carreau, A., Cairns, N.J., Smirnova, T., (2003) J. Biol. Chem., 278, pp. 6521-6531
Lenney, J.F., Peppers, S.C., Kucera-Orallo, C.M., George, R.P., (1985) Biochem. J., 228, pp. 653-660
Otani, H., Okumura, N., Hashida-Okumura, A., Nagai, K., (2005) J. Biochem. (Tokyo), 137, pp. 167-175
Bonomo, R.P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., (2003) J. Chem. Soc., Dalton Trans., pp. 4406-4415
La Mendola, D., Sortino, S., Vecchio, G., Rizzarelli, E., (2002) Helv. Chim. Acta, 85, pp. 1633-1643
Amorini, A.M., Bellia, F., Di Pietro, V., Giardina, B., La Mendola, D., Lazzarino, G., Sortino, S., Vecchio, G., (2007) Eur. J. Med. Chem., 42, pp. 910-920
Bonomo, R.P., Cucinotta, V., D'Alessandro, F., Impellizzeri, G., Maccarrone, G., Vecchio, G., Rizzarelli, E., (1991) Inorg. Chem., 30, pp. 2708-2713
Teranishi, K., Watanabe, K., Hisamatsu, M., Yamada, T., (1998) J. Carbohydr. Chem., 17, pp. 489-494
Lazzarino, G., Amorini, A.M., Fazzina, G., Vagnozzi, R., Signoretti, S., Donzelli, S., Di Stasio, E., Tavazzi, B., (2003) Anal. Biochem., 322, pp. 51-59
Fernandez, M., Fragoso, A., Cao, R., Banos, M., Ansorge-Schumacher, M., Hartmeier, W., Villalonga, R., (2004) J. Mol. Catal., B Enzym., 31, pp. 47-52
Schaschke, N., Fiori, S., Weyher, E., Escrieut, C., Fourmy, D., Mueller, G., Moroder, L., (1998) J. Am. Chem. Soc., 120, pp. 7030-7038
E. Rizzarelli, G. Vecchio, D. La Mendola, Eur. Pat. Appl. 1176154, 2002Donze, C., Rizzarelli, E., Vecchio, G., (1998) Supramol. Chem., 10, pp. 33-42
Vecchio, G., La Mendola, D., Rizzarelli, E., (2001) J. Supramol. Chem., 1, pp. 87-95
Di Blasio, B., Galdiero, S., Saviano, M., Pedone, C., Benedetti, E., Rizzarelli, E., Pedotti, S., Gibbons, W.A., (1996) Carbohydr. Res., 282, pp. 41-52
Chen, W.-H., Yuan, D.-Q., Fujita, K., (1996) Tetrahedron Lett., 37, pp. 7561-7564
Fujita, K., Chen, W.-H., Yuan, D.-Q., Nogami, Y., Koga, T., Fujioka, T., Mihashi, K., Lichtenthaler, F.W., (1999) Tetrahedron: Asymmetry, 10, pp. 1689-1696
Fujita, K., Ohta, K., Ikegami, Y., Shimada, H., Tahara, T., Nogami, Y., Koga, T., Nakajima, T., (1994) Tetrahedron Lett., 35, pp. 9577-9580
Bonomo, R.P., Maccarrone, G., Rizzarelli, E., Vecchio, G., (2002) Inorg. Chim. Acta, 339, pp. 455-460
Cucinotta, V., Giuffrida, A., La Mendola, D., Maccarrone, G., Puglisi, A., Rizzarelli, E., Vecchio, G., (2004) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 800, pp. 127-133
Nogami, Y., Nasu, K., Koga, T., Ohta, K., Fujita, K., Immel, S., Lindner, H.J., Lichtenthaler, F.W., (1997) Angew. Chem., Int. Ed. Engl., 36, pp. 1899-1902
Janssen, B., Hohenadel, D., Brinkkoetter, P., Peters, V., Rind, N., Fischer, C., Rychlik, I., van der Woude, F.J., (2005) Diabetes, 54, pp. 2320-2327
Lee, Y.T., Hsu, C.C., Lin, M.H., Liu, K.S., Yin, M.C., (2005) Eur. J. Pharmacol., 513, pp. 145-150
Guiotto, A., Calderan, A., Ruzza, P., Osler, A., Rubini, C., Jo, D.G., Mattson, M.P., Borin, G., (2005) J. Med. Chem., 48, pp. 6156-6161
Jin, C.L., Yang, L.X., Wu, X.H., Li, Q., Ding, M.P., Fan, Y.Y., Zhang, W.P., Chen, Z., (2005) Neuroscience, 135, pp. 939-947
Babizhayev, M.A., (2005) Drugs R D, 6, pp. 345-369
Babizhayev, M.A., Deyev, A.I., Yermakova, V.N., Semiletov, Y.A., Davydova, N.G., Kurysheva, N.I., Zhukotskii, A.V., Goldman, I.M., (2001) Peptides, 22, pp. 979-994
Aldini, G., Facino, R.M., Beretta, G., Carini, M., (2005) Biofactors, 24, pp. 77-87
Roesel, R.A., Kearse, E.C., Blankeship, P.R., (1986) Fed. Proc., 45, p. 470
Calabrese, V., Colombrita, C., Guagliano, E., Sapienza, M., Ravagna, A., Cardile, V., Scapagnini, G., Rizzarelli, E., (2005) Neurochem. Res., 30, pp. 797-807
Boldyrev, A., Bulygina, E., Leinsoo, T., Petrushanko, I., Tsubone, S., Abe, H., (2004) Comp. Biochem. Physiol. Biochem. Mol. Biol., 137, pp. 81-88
Nadi, N. S., Hirsch, J. D., Margolis, F. L., (1980) J. Neurochem., 34, pp. 138-146
Baslow, M. H., (2002) Neurochem. Int., 40, pp. 295-300
Baslow, M. H., Dyakin, V. V., Nowak, K. L., Hungund, B. L., Guilfoyle, D. N., (2005) J. Mol. Neurosci., 26, pp. 1-15
Baslow, M. H., Suckow, R. F., Berg, M. J., Marks, N., Saito, M., Bhakoo, K. K., (2001) J. Mol. Neurosci., 17, pp. 351-359
Boldyrev, A. A., Dupin, A. M., Pindel, E. V., Severin, S. E., (1988) Comp. Biochem. Physiol., B, 89, pp. 245-250
Boldyrev, A. A., Johnson, P., Wei, Y., Tan, Y., Carpenter, D. O., (1999) Neurosci. Lett., 263, pp. 169-172
Hipkiss, A. R., Brownson, C., Bertani, M. F., Ruiz, E., Ferro, A., (2002) Ann. N. Y. Acad. Sci., 959, pp. 285-294
Seidler, N. W., Yeargans, G. S., Morgan, T. G., (2004) Arch. Biochem. Biophys., 427, pp. 110-115
Kang, J. H., Kim, K. S., (2003) Mol. Cell, 15, pp. 87-93
Jackson, M. C., Kucera, C. M., Lenney, J. F., (1991) Clin. Chim. Acta, 196, pp. 193-205
Lenney, J. F., George, R. P., Weiss, A. M., Kucera, C. M., Chan, P. W., Rinzler, G. S., (1982) Clin. Chim. Acta, 123, pp. 221-231
Lenney, J. F., Peppers, S. C., Kucera-Orallo, C. M., George, R. P., (1985) Biochem. J., 228, pp. 653-660
Bonomo, R. P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., (2003) J. Chem. Soc., Dalton Trans., pp. 4406-4415
Amorini, A. M., Bellia, F., Di Pietro, V., Giardina, B., La Mendola, D., Lazzarino, G., Sortino, S., Vecchio, G., (2007) Eur. J. Med. Chem., 42, pp. 910-920
Bonomo, R. P., Cucinotta, V., D'Alessandro, F., Impellizzeri, G., Maccarrone, G., Vecchio, G., Rizzarelli, E., (1991) Inorg. Chem., 30, pp. 2708-2713
Chen, W. -H., Yuan, D. -Q., Fujita, K., (1996) Tetrahedron Lett., 37, pp. 7561-7564
Bonomo, R. P., Maccarrone, G., Rizzarelli, E., Vecchio, G., (2002) Inorg. Chim. Acta, 339, pp. 455-460
Lee, Y. T., Hsu, C. C., Lin, M. H., Liu, K. S., Yin, M. C., (2005) Eur. J. Pharmacol., 513, pp. 145-150
Jin, C. L., Yang, L. X., Wu, X. H., Li, Q., Ding, M. P., Fan, Y. Y., Zhang, W. P., Chen, Z., (2005) Neuroscience, 135, pp. 939-947
Babizhayev, M. A., (2005) Drugs R D, 6, pp. 345-369
Roesel, R. A., Kearse, E. C., Blankeship, P. R., (1986) Fed. Proc., 45, p. 470
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 2.882, 5-year impact factor: 3.114
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-38949163284&partnerID=40&md5=f04150fd1c1d1b248f754fc7876883e3
Keywords: β-Cyclodextrin, Anserine, Antioxidant Activity, Carnosine, Homocarnosine, Neurodegeneration, Aminoacylhistidine Dipeptidase, Beta Cyclodextrin, Copper Ion, Dipeptide Derivative, Enzyme, Glycoside, Malonaldehyde, Unclassified Drug, Animal Tissue, Article, Enzyme Activity, Hydrolysis, Mass Spectrometry, Nonhuman, Proton Nuclear Magnetic Resonance, ß-Cyclodextrin,
Affiliations:
*** IBB - CNR ***
Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
CNR Institute of Biostructure and Bioimaging, Viale A. Doria 6, 95125 Catania, Italy
Institute of Biochemistry and Clinical Biochemistry, Catholic University of Rome, Largo F. Vito 1, 00164 Rome, Italy
References:
Neidle, A., Kandera, J., (1974) Brain Res., 80, pp. 359-36
Sobue, K., Konishi, H., Nakajima, T., (1975) J. Neurochem., 24, pp. 1261-1262
Bonfanti, L., Peretto, P., De Marchis, S., Fasolo, A., (1999) Prog. Neurobiol., 59, pp. 333-353
Nadi, N.S., Hirsch, J.D., Margolis, F.L., (1980) J. Neurochem., 34, pp. 138-146
Baslow, M.H., (2002) Neurochem. Int., 40, pp. 295-300
Baslow, M.H., (2003) Neurochem. Res., 28, pp. 941-953
Baslow, M.H., Dyakin, V.V., Nowak, K.L., Hungund, B.L., Guilfoyle, D.N., (2005) J. Mol. Neurosci., 26, pp. 1-15
Baslow, M.H., Suckow, R.F., Berg, M.J., Marks, N., Saito, M., Bhakoo, K.K., (2001) J. Mol. Neurosci., 17, pp. 351-359
Boldyrev, A.A., Dupin, A.M., Pindel, E.V., Severin, S.E., (1988) Comp. Biochem. Physiol., B, 89, pp. 245-250
Boldyrev, A.A., Johnson, P., Wei, Y., Tan, Y., Carpenter, D.O., (1999) Neurosci. Lett., 263, pp. 169-172
Kohen, R., Yamamoto, Y., Cundy, K.C., Ames, B.N., (1988) Proc. Natl. Acad. Sci. U.S.A., 85, pp. 3175-3179
Cuzzocrea, S., Genovese, T., Failla, M., Vecchio, G., Fruciano, M., Mazzon, E., Di Paola, R., Vancheri, C., (2007) Am. J. Physiol., 292, pp. L1095-L1104
Abe, H., (2000) Biochemistry (Mosc.), 65, pp. 757-765
Hipkiss, A.R., Brownson, C., Bertani, M.F., Ruiz, E., Ferro, A., (2002) Ann. N.Y. Acad. Sci., 959, pp. 285-294
Seidler, N.W., Yeargans, G.S., Morgan, T.G., (2004) Arch. Biochem. Biophys., 427, pp. 110-115
Boldyrev, A., Koudinov, A., Berezov, T., Carpenter, D.O., (2004) J. Alzheimers Dis., 6, pp. 633-638. , discussion 673-681
Dukic-Stefanovic, S., Schinzel, R., Riederer, P., Munch, G., (2001) Biogerontology, 2, pp. 19-34
Kang, J.H., Kim, K.S., (2003) Mol. Cell, 15, pp. 87-93
Munch, G., Mayer, S., Michaelis, J., Hipkiss, A.R., Riederer, P., Muller, R., Neumann, A., Cunningham, A.M., (1997) Biochim. Biophys. Acta, 1360, pp. 17-29
Jackson, M.C., Kucera, C.M., Lenney, J.F., (1991) Clin. Chim. Acta, 196, pp. 193-205
Lenney, J.F., George, R.P., Weiss, A.M., Kucera, C.M., Chan, P.W., Rinzler, G.S., (1982) Clin. Chim. Acta, 123, pp. 221-231
Teufel, M., Saudek, V., Ledig, J.-P., Bernhardt, A., Boularand, S., Carreau, A., Cairns, N.J., Smirnova, T., (2003) J. Biol. Chem., 278, pp. 6521-6531
Lenney, J.F., Peppers, S.C., Kucera-Orallo, C.M., George, R.P., (1985) Biochem. J., 228, pp. 653-660
Otani, H., Okumura, N., Hashida-Okumura, A., Nagai, K., (2005) J. Biochem. (Tokyo), 137, pp. 167-175
Bonomo, R.P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., (2003) J. Chem. Soc., Dalton Trans., pp. 4406-4415
La Mendola, D., Sortino, S., Vecchio, G., Rizzarelli, E., (2002) Helv. Chim. Acta, 85, pp. 1633-1643
Amorini, A.M., Bellia, F., Di Pietro, V., Giardina, B., La Mendola, D., Lazzarino, G., Sortino, S., Vecchio, G., (2007) Eur. J. Med. Chem., 42, pp. 910-920
Bonomo, R.P., Cucinotta, V., D'Alessandro, F., Impellizzeri, G., Maccarrone, G., Vecchio, G., Rizzarelli, E., (1991) Inorg. Chem., 30, pp. 2708-2713
Teranishi, K., Watanabe, K., Hisamatsu, M., Yamada, T., (1998) J. Carbohydr. Chem., 17, pp. 489-494
Lazzarino, G., Amorini, A.M., Fazzina, G., Vagnozzi, R., Signoretti, S., Donzelli, S., Di Stasio, E., Tavazzi, B., (2003) Anal. Biochem., 322, pp. 51-59
Fernandez, M., Fragoso, A., Cao, R., Banos, M., Ansorge-Schumacher, M., Hartmeier, W., Villalonga, R., (2004) J. Mol. Catal., B Enzym., 31, pp. 47-52
Schaschke, N., Fiori, S., Weyher, E., Escrieut, C., Fourmy, D., Mueller, G., Moroder, L., (1998) J. Am. Chem. Soc., 120, pp. 7030-7038
E. Rizzarelli, G. Vecchio, D. La Mendola, Eur. Pat. Appl. 1176154, 2002Donze, C., Rizzarelli, E., Vecchio, G., (1998) Supramol. Chem., 10, pp. 33-42
Vecchio, G., La Mendola, D., Rizzarelli, E., (2001) J. Supramol. Chem., 1, pp. 87-95
Di Blasio, B., Galdiero, S., Saviano, M., Pedone, C., Benedetti, E., Rizzarelli, E., Pedotti, S., Gibbons, W.A., (1996) Carbohydr. Res., 282, pp. 41-52
Chen, W.-H., Yuan, D.-Q., Fujita, K., (1996) Tetrahedron Lett., 37, pp. 7561-7564
Fujita, K., Chen, W.-H., Yuan, D.-Q., Nogami, Y., Koga, T., Fujioka, T., Mihashi, K., Lichtenthaler, F.W., (1999) Tetrahedron: Asymmetry, 10, pp. 1689-1696
Fujita, K., Ohta, K., Ikegami, Y., Shimada, H., Tahara, T., Nogami, Y., Koga, T., Nakajima, T., (1994) Tetrahedron Lett., 35, pp. 9577-9580
Bonomo, R.P., Maccarrone, G., Rizzarelli, E., Vecchio, G., (2002) Inorg. Chim. Acta, 339, pp. 455-460
Cucinotta, V., Giuffrida, A., La Mendola, D., Maccarrone, G., Puglisi, A., Rizzarelli, E., Vecchio, G., (2004) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 800, pp. 127-133
Nogami, Y., Nasu, K., Koga, T., Ohta, K., Fujita, K., Immel, S., Lindner, H.J., Lichtenthaler, F.W., (1997) Angew. Chem., Int. Ed. Engl., 36, pp. 1899-1902
Janssen, B., Hohenadel, D., Brinkkoetter, P., Peters, V., Rind, N., Fischer, C., Rychlik, I., van der Woude, F.J., (2005) Diabetes, 54, pp. 2320-2327
Lee, Y.T., Hsu, C.C., Lin, M.H., Liu, K.S., Yin, M.C., (2005) Eur. J. Pharmacol., 513, pp. 145-150
Guiotto, A., Calderan, A., Ruzza, P., Osler, A., Rubini, C., Jo, D.G., Mattson, M.P., Borin, G., (2005) J. Med. Chem., 48, pp. 6156-6161
Jin, C.L., Yang, L.X., Wu, X.H., Li, Q., Ding, M.P., Fan, Y.Y., Zhang, W.P., Chen, Z., (2005) Neuroscience, 135, pp. 939-947
Babizhayev, M.A., (2005) Drugs R D, 6, pp. 345-369
Babizhayev, M.A., Deyev, A.I., Yermakova, V.N., Semiletov, Y.A., Davydova, N.G., Kurysheva, N.I., Zhukotskii, A.V., Goldman, I.M., (2001) Peptides, 22, pp. 979-994
Aldini, G., Facino, R.M., Beretta, G., Carini, M., (2005) Biofactors, 24, pp. 77-87
Roesel, R.A., Kearse, E.C., Blankeship, P.R., (1986) Fed. Proc., 45, p. 470
Calabrese, V., Colombrita, C., Guagliano, E., Sapienza, M., Ravagna, A., Cardile, V., Scapagnini, G., Rizzarelli, E., (2005) Neurochem. Res., 30, pp. 797-807
Boldyrev, A., Bulygina, E., Leinsoo, T., Petrushanko, I., Tsubone, S., Abe, H., (2004) Comp. Biochem. Physiol. Biochem. Mol. Biol., 137, pp. 81-88
Nadi, N. S., Hirsch, J. D., Margolis, F. L., (1980) J. Neurochem., 34, pp. 138-146
Baslow, M. H., (2002) Neurochem. Int., 40, pp. 295-300
Baslow, M. H., Dyakin, V. V., Nowak, K. L., Hungund, B. L., Guilfoyle, D. N., (2005) J. Mol. Neurosci., 26, pp. 1-15
Baslow, M. H., Suckow, R. F., Berg, M. J., Marks, N., Saito, M., Bhakoo, K. K., (2001) J. Mol. Neurosci., 17, pp. 351-359
Boldyrev, A. A., Dupin, A. M., Pindel, E. V., Severin, S. E., (1988) Comp. Biochem. Physiol., B, 89, pp. 245-250
Boldyrev, A. A., Johnson, P., Wei, Y., Tan, Y., Carpenter, D. O., (1999) Neurosci. Lett., 263, pp. 169-172
Hipkiss, A. R., Brownson, C., Bertani, M. F., Ruiz, E., Ferro, A., (2002) Ann. N. Y. Acad. Sci., 959, pp. 285-294
Seidler, N. W., Yeargans, G. S., Morgan, T. G., (2004) Arch. Biochem. Biophys., 427, pp. 110-115
Kang, J. H., Kim, K. S., (2003) Mol. Cell, 15, pp. 87-93
Jackson, M. C., Kucera, C. M., Lenney, J. F., (1991) Clin. Chim. Acta, 196, pp. 193-205
Lenney, J. F., George, R. P., Weiss, A. M., Kucera, C. M., Chan, P. W., Rinzler, G. S., (1982) Clin. Chim. Acta, 123, pp. 221-231
Lenney, J. F., Peppers, S. C., Kucera-Orallo, C. M., George, R. P., (1985) Biochem. J., 228, pp. 653-660
Bonomo, R. P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., Maccarrone, G., Nicoletti, F., Vecchio, G., (2003) J. Chem. Soc., Dalton Trans., pp. 4406-4415
Amorini, A. M., Bellia, F., Di Pietro, V., Giardina, B., La Mendola, D., Lazzarino, G., Sortino, S., Vecchio, G., (2007) Eur. J. Med. Chem., 42, pp. 910-920
Bonomo, R. P., Cucinotta, V., D'Alessandro, F., Impellizzeri, G., Maccarrone, G., Vecchio, G., Rizzarelli, E., (1991) Inorg. Chem., 30, pp. 2708-2713
Chen, W. -H., Yuan, D. -Q., Fujita, K., (1996) Tetrahedron Lett., 37, pp. 7561-7564
Bonomo, R. P., Maccarrone, G., Rizzarelli, E., Vecchio, G., (2002) Inorg. Chim. Acta, 339, pp. 455-460
Lee, Y. T., Hsu, C. C., Lin, M. H., Liu, K. S., Yin, M. C., (2005) Eur. J. Pharmacol., 513, pp. 145-150
Jin, C. L., Yang, L. X., Wu, X. H., Li, Q., Ding, M. P., Fan, Y. Y., Zhang, W. P., Chen, Z., (2005) Neuroscience, 135, pp. 939-947
Babizhayev, M. A., (2005) Drugs R D, 6, pp. 345-369
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New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity
Synthesis, antioxidant properties and resistance to carnosinase hydrolysis of histidine-containing dipeptides are reported in this study. Carnosine (beta-alanyl-l-histidine), homocarnosine (gamma-aminobutyryl-l-histidine) and anserine (beta-alanyl-3-methyl-l-histidine) were covalently derivatized with beta-cyclodextrin to form different OH- or NH-bound conjugates. Mass spectroscopic and (1)H NMR data were used to determine the structure and the purity of the various beta-cyclodextrin derivatives. The inhibitory effect towards oxidation of human LDL induced by Cu(2+) ions, was estimated by measuring malondialdehyde formation as a function of increasing concentrations of these newly synthesized compounds (the beta-cyclodextrin-anserine conjugated in 3 had the highest antioxidant effect). All derivatives had higher antioxidant effects than those of the corresponding free histidine-containing dipeptides. Resistance to rat brain carnosinase hydrolysis of the most active derivatives indicated that these compounds are good candidates for further studies in more complex cellular and animal models. Their possible applications for remedies in neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases, are discussed.
Synthesis, antioxidant properties and resistance to carnosinase hydrolysis of histidine-containing dipeptides are reported in this study. Carnosine (beta-alanyl-l-histidine), homocarnosine (gamma-aminobutyryl-l-histidine) and anserine (beta-alanyl-3-methyl-l-histidine) were covalently derivatized with beta-cyclodextrin to form different OH- or NH-bound conjugates. Mass spectroscopic and (1)H NMR data were used to determine the structure and the purity of the various beta-cyclodextrin derivatives. The inhibitory effect towards oxidation of human LDL induced by Cu(2+) ions, was estimated by measuring malondialdehyde formation as a function of increasing concentrations of these newly synthesized compounds (the beta-cyclodextrin-anserine conjugated in 3 had the highest antioxidant effect). All derivatives had higher antioxidant effects than those of the corresponding free histidine-containing dipeptides. Resistance to rat brain carnosinase hydrolysis of the most active derivatives indicated that these compounds are good candidates for further studies in more complex cellular and animal models. Their possible applications for remedies in neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases, are discussed.
New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity
New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity
Other filter: ([btitle,keywords] "β-Cyclodextrin" OR ...
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Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (366 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
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Di Blasio B, Galdiero S, Saviano M, De Simone G, Benedetti E, Pedone C, Gibbons WA, Deschenaux R, Rizzarelli E, Vecchio G
Functionalized cyclodextrins: Synthesis and structural characterization of 6-deoxy-6-{4-[N-tert-butoxycarbonyl-2-aminoethyl]-imidazolyl}-cyclomaltoheptaose (326 views)
Supramol Chem (ISSN: 1061-0278), 1996; 7(1): 47-54.
Impact Factor: 3.19
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DALESSANDRO F, GULINO F, IMPELLIZZERI G, PAPPALARDO G, RIZZARELLI E, SCIOTTO D, VECCHIO G
A new water soluble host compound possessing two different hydrophobic recognition cavities: Calix[4]arene derivative conjugated with monofunctionalized β-cyclodextrin (425 views)
Tetrahedron Lett (ISSN: 0040-4039), 1994 Jan 24; 35(4): 629-632.
Impact Factor: 2.5
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Cucinotta V, Mangano A, Nobile G, Santoro AM, Vecchio G
New platinum(II) complexes of β-cyclodextrin diamine derivatives and their antitumor activity (468 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Nov 15; 52(3): 183-190.
Impact Factor: 1.342
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Di Blasio B, Pavone V, Nastri F, Isernia C, Saviano M, Pedone C, Cucinotta V, Impellizzeri G, Rizzarelli E, Vecchio G
Conformation for a β-cyclodextrin monosubstituted with a cyclic dipeptide (485 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 1992 Sep 1; 89(15): 7218-7221.
Impact Factor: 9.04
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* Validation of FDG-PET datasets of normal controls for the extraction of SPM-based brain metabolism maps (6 views)
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070linking), 2021 Jul; 48(8): 2486-2499.
Impact Factor: 9.236
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Rendina A, Drongitis D, Donizetti A, Fucci L, Milan G, Tripodi F, Giustezza F, Postiglione A, Pappata S, Ferrari R, Bossù P, Angiolillo A, Di Costanzo A, Caiazzo M, Vitale E
* CD33 and SIGLECL1 Immunoglobulin Superfamily Involved in Dementia (94 views)
J Neuropathol Exp Neurol (ISSN: 0022-3069linking), 2020 Jul 10; 79(8): 891-901.
Impact Factor: 3.51
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Dubbioso R, Ruggiero L, Esposito M, Tarantino P, De Angelis M, Aruta F, Pappata S, Ugga L, Piperno A, Iorio R, Santoro L, Iodice R, Manganelli F
* Different cortical excitability profiles in hereditary brain iron and copper accumulation (131 views)
Neurol Sci (ISSN: 1590-1874linking, 1590-3478), 2020 Mar; 41(3): 679-685.
Impact Factor: 1.315
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Spampinato SF, Copani A, Nicoletti F, Sortino MA, Caraci F
* Metabotropic Glutamate Receptors in Glial Cells: A New Potential Target for Neuroprotection? (246 views)
Front Mol Neurosci (ISSN: 1662-5099, 1662-5099linking, 1662-5099electronic), 2018 Nov 13; 11: 414-414.
Impact Factor: 3.902
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Oliveri V, Zimbone S, Giuffrida ML, Bellia F, Tomasello MF, Vecchio G
* Porphyrin Cyclodextrin Conjugates Modulate Amyloid Beta Peptide Aggregation and Cytotoxicity (362 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(24): 6349-6353.
Impact Factor: 5.476
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Sciacca MFM, Romanucci V, Zarrelli A, Monaco I, Lolicato F, Spinella N, Galati C, Grasso G, D'Urso L, Romeo M, Diomede L, Salmona M, Bongiorno C, Di Fabio G, La Rosa C, Milardi D
* Inhibition of Abeta Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry (401 views) (PDF 194 views)
Acs Chem Neurosci (ISSN: 1948-7193, 1948-7193electronic), 2017 Jun 09; N/D: N/D-N/D.
Impact Factor: 4.211
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Grasso G, Santoro AM, Lanza V, Sbardella D, Tundo GR, Ciaccio C, Marini S, Coletta M, Milardi D
* The double faced role of copper in Ab homeostasis: A survey on the interrelationship between metal dyshomeostasis, UPS functioning and autophagy in neurodegeneration (268 views)
Coordination Chemistry Reviews, 2017 Jun; N/D: 1-22.
Impact Factor: 13.324
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Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Sciacca MFM, Sinopoli A, Milardi D, Pappalardo G, De Spirito M, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G
* Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies (262 views)
Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2017 Apr 22; N/D: N/D-N/D.
Impact Factor: 5.168
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Caraci F, Bruno V, Copani A, Matrisciano F, Nicoletti F, Battaglia G
* The impact of metabotropic glutamate receptors into active neurodegenerative processes: A "dark side" in the development of new symptomatic treatments for neurologic and psychiatric disorders (291 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2017 Mar 15; 115: 180-192.
Impact Factor: 5.012
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Sandomenico A, Severino V, Apone F, De Lucia A, Caporale A, Doti N, Russo A, Russo R, Rega C, Del Giacco T, Falcigno L, Ruvo M, Chambery A
* Trifluoroacetylated tyrosine-rich D-tetrapeptides have potent antioxidant activity (401 views)
Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 2017 Mar; 89: 50-59.
Impact Factor: 2.851
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D'Andrea LD, Rosa LD, Vigliotti C, Cataldi M
* VEGF mimic peptides: Potential applications in central nervous system therapeutics (639 views)
New Horizons Transl Med (ISSN: 2307-5023), 2017; 3(5): 233-251.
Impact Factor: 0
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Oliveri V, Bellia F, Grasso GI, Pietropaolo A, Vecchio G
* Trehalose-8-hydroxyquinoline conjugates as antioxidant modulators of Aβ aggregation (942 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(53): 47229-47236.
Impact Factor: 3.108
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Caso JV, Russo L, Palmieri M, Malgieri G, Galdiero S, Falanga A, Isernia C, Iacovino R
* Investigating the inclusion properties of aromatic amino acids complexing beta-cyclodextrins in model peptides (418 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015; N/D: N/D-N/D.
Impact Factor: 3.196
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Salvatore E, Tedeschi E, Mollica C, Vicidomini C, Varrone A, Coda ARD, Brunetti A, Salvatore M, De Michele G, Filla A, Pappata S
* Supratentorial and infratentorial damage in spinocerebellar ataxia 2: a diffusion-weighted MRI study (376 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2014 May; 29(6): 780-786.
Impact Factor: 5.68
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Bellia F, Vecchio G, Rizzarelli E
* Carnosinases, Their Substrates And Diseases (659 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2014 Feb 21; 19(2): 2299-2329.
Impact Factor: 2.416
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Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
* Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound (560 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Feb; 131: 56-63.
Impact Factor: 3.444
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Dathan NA, Alterio V, Troiano E, Vullo D, Ludwig M, De Simone G, Supuran CT, Monti SM
* Biochemical Characterization Of The Chloroplastic β-Carbonic Anhydrase From Flaveria Bidentis (l. ) "kuntze" (449 views)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2014; 29(4): 500-504.
Impact Factor: 2.332
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine and Cognitive Deficits (171 views)
Diet And Nutr In Dement And Cogn Decline (ISSN: 9780-1240793979780124078246), 2014; N/D: 973-982.
Impact Factor: 0
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (509 views)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
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Caraci F, Battaglia G, Sortino MA, Spampinato S, Molinaro G, Copani A, Nicoletti F, Bruno V
* Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic? (626 views)
Neurochem Int (ISSN: 0197-0186), 2012 Sep; 61(4): 559-565.
Impact Factor: 2.659
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
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Riccio A, Cubellis MV
* Gain of function in CDKN1C (503 views)
Nature Genetics (ISSN: 1061-4036), 2012 Jul; 44(7): 737-738.
Impact Factor: 35.209
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (3606 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (535 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Arena G, Fattorusso R, Grasso G, Grasso GI, Isernia C, Malgieri G, Milardi D, Rizzarelli E
* Zinc(II) complexes of ubiquitin: speciation, affinity and binding features (559 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Oct 4; 17(41): 11596-11603.
Impact Factor: 5.925
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Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ
* Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity (880 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 279-304.
Impact Factor: 9.97
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Cucinotta V, Giuffrida A, Grasso G, MacCarrone G, Mazzaglia A, Messina M, Vecchio G
* Diaminotrehalose-capped β-cyclodextrin, a new member of hemispherodextrins: Synthesis, thermodynamic and spectroscopic characterization and its exploitation in chiral electrokinetic chromatography (400 views)
J Sep Sci (ISSN: 1615-9306), 2011 Jan; 34(1): 70-76.
Impact Factor: 2.733
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Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (539 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
* Carnosinase levels in aging brain: redox state induction and cellular stress response (415 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2759-2775.
Impact Factor: 7.581
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion Proteins Leading to Neurodegeneration (vol 5, pg 579, 2008) (233 views)
Current Alzheimer Research (ISSN: 1567-2050), 2009 Jun; 6(3): N/D-N/D.
Impact Factor: 4.971
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La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion proteins leading to neurodegeneration (420 views)
Current Alzheimer Research (ISSN: 1567-2050), 2008 Dec; 5(6): 579-590.
Impact Factor: 4.132
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (388 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Impact Factor: 2.26
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Gustavsson T, Banyasz A, Sarkar N, Markovitsi D, Improta R
* Statin: New life for an old drug (365 views)
Pharmacol Res Academic Press, 2008 Jun 23; 350(1-3): 1-2.
Impact Factor: 3.976
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Copani A, Guccione S, Giurato L, Caraci F, Calafiore M, Sortino MA
* The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development (452 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2008; 15(24): 2420-2432.
Impact Factor: 4.823
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (753 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Nicoletti VG, Santoro AM, Grasso G, Vagliasindi LI, Giuffrida ML, Cuppari C, Purrello VS, Stella AMG, Rizzarelli E
* Carnosine interaction with nitric oxide and astroglial cell protection (648 views)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2007 Sep 1; 85(10): 2239-2245.
Impact Factor: 3.268
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Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
* Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates (370 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.
Impact Factor: 2.301
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Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
* Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity (254 views)
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.
Impact Factor: 1.713
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Cucinotta V, Giuffrida A, Maccarrone G, Messina M, Puglisi A, Rizzarelli E, Vecchio G
* Coordination properties of 3-functionalized β-cyclodextrins. Thermodynamic stereoselectivity of copper(II) complexes of the A, B-diamino derivative and its exploitation in LECE (356 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Sep 21; (16): 2731-2736.
Impact Factor: 3.003
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Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (669 views)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
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Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (348 views)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
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Cucinotta V, Giuffrida A, La Mendola D, Maccarrone G, Puglisi A, Rizzarelli E, Vecchio G
* 3-Amino Derivative Of Beta-Cyclodextrin: Thermodynamics Of Copper (ii) Complexes And Exploitation Of Its Enantioselectivity In The Separation Of Amino Acid Racemates By Ligand Exchange Capillary Electrophoresis (350 views)
And Life Sciencesjournal Of Chromatography B Analytical Technologies In The Biomedical, 2004 Feb 5; 800(1-2): 127-133.
Impact Factor: 1.403
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Mineo P, Vitalini D, La Mendola D, Rizzarelli E, Scamporrino E, Vecchio G
* Coordination Features Of Difunctionalized Beta-Cyclodextrins With Carnosine: Esi-Ms And Spectroscopic Investigations On 6a, 6d-Di-(beta-Alanyl-L-Histidine)-6a, 6d-Dideoxy-Beta-Cyclodextrin And 6a, 6c-Di-(beta-Alanyl-L-Histidine)-6a, 6c-Dideoxy-Beta-Cyclodextrin And Their Copper (ii) Complexes (429 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2004 Feb; 98(2): 254-265.
Impact Factor: 2.225
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (437 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Bonomo RP, Bruno V, Conte E, De Guidi G, La Mendola D, Maccarrone G, Nicoletti F, Rizzarelli E, Sortino S, Vecchio G
* Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (385 views)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2003; (23): 4406-4415.
Impact Factor: 2.908
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Borrelli RC, Fogliano V, Monti SM, Ames JM
* Characterization of melanoidins from a glucose-glycine model system (243 views)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(3): 210-215.
Impact Factor: 1.021
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Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (883 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
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Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (564 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
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Impellizzeri G, Pappalardo G, D'Alessandro F, Rizzarelli E, Saviano M, Iacovino R, Benedetti E, Pedone C
Erratum: Solid state and solution conformation of 6-{4-[N-tert- butoxycarbonyl-N-(N'-ethyl)propanamide]imidazolyl}-6- deoxycyclomaltoheptaose: Evidence of self-inclusion of the boc group within the β-cyclodextrin cavity (European Journal of Organic Chemistry (2000) (1065-1076)) (447 views)
Eur J Org Chem (ISSN: 1434-193x), 2000; (12): 2345-2345.
Impact Factor: 2.15
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Impellizzeri G, Pappalardo G, D'Alessandro F, Rizzarelli E, Saviano M, Iacovino R, Benedetti E, Pedone C
Solid state and solution conformation of 6-{4-[N-tert-butoxycarbonyl-N- (N'-ethyl)propanamide]imidazolyl}-6-deoxycyclomaltoheptaose: Evidence of self-inclusion of the Boc group within the β-cyclodextrin cavity (360 views)
European J Org Chem (ISSN: 1434-193x), 2000; (6): 1065-1076.
Impact Factor: 2.15
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Fogliano V, Ritieni A, Monti SM, Gallo M, Della Medaglia D, Ambrosino ML, Sacchi R
Antioxidant activity of virgin olive oil phenolic compounds in a micellar system (301 views)
Journal Of The Science Of Food And Agriculture (ISSN: 0022-5142), 1999 Oct; 79(13): 1803-1808.
Impact Factor: 1.097
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Campagna T, Grasso G, Rizzarelli E, Vecchio G
L- and D-cysteine derivatives of β-cyclodextrin: Different molecular recognition properties of their copper(II) complexes for amino acids (333 views)
Inorg Chim Acta (ISSN: 0020-1693), 1998; 275-276: 395-400.
Impact Factor: 1.454
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Bonomo RP, Cucinotta V, D'Alessandro F, Impellizzeri G, Maccarrone G, Rizzarelli E, Vecchio G, Carima L, Corradini R, Sartor G, Marchelli R
Chiral recognition by the copper(ii) complex of 6-deoxy-6-n-(2 - methylaminopyridine)-β-cyclodextrin (378 views)
Chirality (ISSN: 0899-0042), 1997; 9(4): 341-349.
Impact Factor: 1.915
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Bonomo RP, Pedotti S, Vecchio G, Rizzarelli E
Molecular Recognition of Amino Acids by Copper(II) Complexes of 6A, 6X-Diamino-6A, 6 X-dideoxy-β-cyclodextrin (X = B, C, D) (254 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Nov 6; 35(23): 6873-6877.
Impact Factor: 2.736
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Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (685 views)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
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Di Blasio B, Galdiero S, Saviano M, Pedone C, Benedetti E, Rizzarelli E, Pedotti S, Vecchio G, Gibbons WA
Synthesis And Structural Characterization Of 6i, 6ii-Diamino-6i, 6ii-Dideoxy-Cyclomaltoheptaose, A Difunctionalized Beta-Cyclodextrin (426 views)
Carbohydr Res, 1996 Feb 28; 282(1): 41-52.
Impact Factor: 0
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Cucinotta V, Grasso G, Pedotti S, Rizzarelli E, Vecchio G, Di Blasio B, Isernia C, Saviano M, Pedone C
A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose (410 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996; 35(26): 7535-7540.
Impact Factor: 2.736
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Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (366 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
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Di Blasio B, Galdiero S, Saviano M, De Simone G, Benedetti E, Pedone C, Gibbons WA, Deschenaux R, Rizzarelli E, Vecchio G
Functionalized cyclodextrins: Synthesis and structural characterization of 6-deoxy-6-{4-[N-tert-butoxycarbonyl-2-aminoethyl]-imidazolyl}-cyclomaltoheptaose (326 views)
Supramol Chem (ISSN: 1061-0278), 1996; 7(1): 47-54.
Impact Factor: 3.19
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DALESSANDRO F, GULINO F, IMPELLIZZERI G, PAPPALARDO G, RIZZARELLI E, SCIOTTO D, VECCHIO G
A new water soluble host compound possessing two different hydrophobic recognition cavities: Calix[4]arene derivative conjugated with monofunctionalized β-cyclodextrin (425 views)
Tetrahedron Lett (ISSN: 0040-4039), 1994 Jan 24; 35(4): 629-632.
Impact Factor: 2.5
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Cucinotta V, Mangano A, Nobile G, Santoro AM, Vecchio G
New platinum(II) complexes of β-cyclodextrin diamine derivatives and their antitumor activity (468 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Nov 15; 52(3): 183-190.
Impact Factor: 1.342
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Di Blasio B, Pavone V, Nastri F, Isernia C, Saviano M, Pedone C, Cucinotta V, Impellizzeri G, Rizzarelli E, Vecchio G
Conformation for a β-cyclodextrin monosubstituted with a cyclic dipeptide (485 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 1992 Sep 1; 89(15): 7218-7221.
Impact Factor: 9.04
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64 Records (62 excluding Abstracts).
Total impact factor: 283.501 (276.38 excluding Abstracts).
Total 5 year impact factor: 291.616 (284.617 excluding Abstracts).
Total impact factor: 283.501 (276.38 excluding Abstracts).
Total 5 year impact factor: 291.616 (284.617 excluding Abstracts).
444 views. Last view on Saturday 14 January 2023, 19:26:21
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