Mild cognitive impairment. Survey of attitudes of specialists and general physicians(613 views) Serrano CM, Allegri RF, Caramelli P, Taragano FE, Camera L
Keywords: Alzheimer, S Disease, Data Collection, Dementia, Mild Cognitive Impairment, Alpha Tocopherol, Cholinesterase Inhibitor, Memantine, Adult, Aged, Alzheimer Disease, Argentina, Article, Brazil, Cognitive Defect, Controlled Study, Disease Classification, Female, General Practitioner, Health Survey, Human, Medical Expert, Medical Specialist, Neurology, Physician Attitude, Psychiatrist, Questionnaire, Standardization, Treatment Planning, Aging, Attitude Of Health Personnel, Cognition Disorders, Vascular, Middle Aged, S Role, Professional Practice, Severity Of Illness Index,
Affiliations: *** IBB - CNR ***
Laboratorio de Investigación de la Memoria del Hospital A. Zubizarreta (GCBA), Buenos Aires, Argentina
Servicio de Neuropsicología (SIREN), Instituto Universitario CEMIC, Galván 4102, 1431 Buenos Aires, Argentina
Unidad de Neurologia Cognitiva y del Comportamiento, Sao Paulo, SP, Brazil
Programa de Medicina Geriátrica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
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Wells, C. E., A deluge of dementia (1981) Psychosomatics, 22, pp. 837-838
Allegri, R. F., Laurent, B., Thomas Anterion, C., Serrano, C. M., La memoria en el envejecimiento, el deterioro cognitivo leve y las demencias (2005) Demencia: Enfoque Multidisciplinario, pp. 351-372. , En Mangone CA, Allegri RF, Arizaga RL, Ollari JA (eds): 3a Ed. Buenos Aires: Editorial Polemos
Jorm, A. F., Korten, A. E., Henderson, A. S., The prevalence of dementia: A quantitative integration of the literature (1987) Acta Psychiatr Scand, 76, pp. 465-479
Jorm, A. F., (1990) The Epidemiology of Alzheimer's Disease and Related Disorders, , London: Chapman and Hall
Mangone, C. A., Allegri, R. F., Arizaga, R. L., Ollari, J. A., Epidemiolog a de la Demencia en pa ses latinoamericanos (1999) Rev Neuropsicol Neuropsiquatr Y Neuroc, 1, pp. 1-4
Arizaga, R. L., Epidemiolog a de las demencias (1995) Enfermedad De Alzheimer: Enfoque Actual, pp. 62-128. , En Mangone CA, Allegri RF, Arizaga RL y Ollari JA. (eds). Buenos Aires: Editorial Argentum
Kral, V. C., Senescent forgetfulness: Benign and malignant (1962) Can Med Assoc J, 86, pp. 257-260
Petersen, R. C., Smith, G., Waring, S., Ivnick, R., Kokmen, E., Tangalos, E., Aging, Memory and Mild Cognitive Impairment (1997) Int Psychogeriatr., 9, pp. 37-43
Petersen, R. C., Diagnosis of Dementia: Diagnostic criteria, rating and early detection (2000) Dementia Update. Educational Program Syllabus, pp. 34-36. , In American Academy of Neurology 3fd
Petersen, R. C., Normal aging, mild cognitive impairment, and early Alzheimer's disease (1995) Neurologist, 1, pp. 326-344
Pag s Larraya, F., Grasso, L., Mar, G., Prevalencia de las demencias de tipo Alzheimer, demencias vasculares y otras demencias en la Rep blica Argentina (2004) Rev Neurol Arg, 29, pp. 148-153
Serrano, C. M., Allegri, R. F., Tratamiento Farmacol gico de las Demencias (2005) El Abordaje Farmacol gico En El Paciente Psiqui trico Adulto, , En Wikinski S y Jufre G (eds). Buenos Aires: Panamericana
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Allegri, R. F., Harris, P., Drake, M., Evaluaci n Neuropsicol gica (2002) Psicogeriatr a: Bases Conceptuales, , En:: Quiroga P y Rohde G (eds). Ediciones de la Sociedad de Neurolog a, Psiquiatr a y Neurocirug a, Chile
Cummings, J. L., Mega, M. S., (2003) Neuropsychiatry and Behavioral Neuroscience, , Oxford: University Press
Zec, R. F., Neuropsychological functioning in Alzheimer's disease (1993) Neuropsychology of Alzheimer's Disease and Other Dementias, pp. 3-80. , In Parks RW, Zec RF, Wilson RS (eds). New York: Oxford University Press
Petersen, R. C., Conceptual Overview (2003) Mild Cognitive Impairment: Aging to Alzheimer's Disease, pp. 1-14. , In Petersen RC (ed.). New York: Oxford University Press
Allegri, R. F., Drake, M., Harris, P., Serrano, C. M., Taragano, F. E., Intrusions in verbal learning in mild cognitive impairment: Prodromal Alzheimer's disease (2005) Neurology, (SUPPL. 1), pp. A165
Kaye, J. A., Swihart, T., Howieson, D., Volume loss of the hippocampus and temporal lobe in healthy elderly person destined to develop dementia (1997) Neurology, 48, pp. 1297-1304
Jack, C. R., Petersen, R. C., Xu, Y. C., Medial temporal atrophy on MRI in normal aging and very mild Alzheimer's disease (1997) Neurology, 49, pp. 786-794
Xu, Y., Jack, C. R., Petersen, R. C., Usefulness of MRI measures of entorhinal cortex versus hippocampus in AD (2000) Neurology, 54, pp. 1760-1767
Johnson, K. A., Albert, M. S., Functional Imaging (2003) Mild Cognitive Impairment: Aging to Alzheimer's Disease, pp. 133-148. , In: Petersen RC (ed.). New York: Oxford University Press
Petersen, R. C., Mild cognitive impairment clinical trials (2003) Nat Rev Drug Discov, 2, pp. 646-653
Petersen, R. C., Thomas, R. G., Grundman, M., Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment (2005) N Engl J Med, 352, pp. 2378-2388
Visser, P. J., Scheltens, P., Verthey, F. R. J., Do MCI criteria in drug trials accurately identify subjects wth predementia Alzheimer's disease? (2005) J Neurol Neurosurg Psychiatty, 76, pp. 1348-1354
Mild cognitive impairment. Survey of attitudes of specialists and general physicians
Mild cognitive impairment (MCI) refers to persons who are slightly cognitively impaired for age but do not meet the criteria for dementia. MCI has been related to a pre-dementia stage of Alzheimer's disease (AD). However, other possible diagnoses such as cerebro-vascular disease, frontotemporal dementia or normal aging have been considered. Diagnosis, etiology and conversion to dementia are a source of ambiguity in MCI. The aim was to evaluate the opinion of experts on dementia and of general practitioners concerning MCI. A total of 24 experts from Argentina and Brazil (16 neurologists and 8 psychiatrists) and 30 general practitioners agreed to reply to a questionnaire on MCI (adapted from Dubois inventory, 2003). Of these, 92% of experts considered MCI as an ambiguous entity, not necessarily as a "pre-dementia" stage; 63% confirmed a tendency to worsen over the time and 83% of experts decided to initiate treatment using cholinesterase inhibitors, memantine and vitamin E. The opinion on MCI was that a priori it is not only an Alzheimer disease pre-dementia stage, but most of them consider the treatment against AD. MCI is a heterogeneous entity that should be classified as an open category and making it necessary to standardize definitions and design diagnosis guides to better understand Alzheimer disease pre-dementia stage.
Mild cognitive impairment. Survey of attitudes of specialists and general physicians
Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, Tomaino C, Muraca MG, Leotta A, Lio SG, Pinessi L, Rainero I, Sorbi S, Nee L, Milan G, Pappata S, Postiglione A, Abbamondi N, Forloni G, St George Hyslop P, Rogaeva E, Bugiani O, Giaccone G, Foncin JF, Spillantini MG, Puccio G * Worldwide distribution of PSEN1 Met146Leu mutation: A large variability for a founder mutation(819 views) Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2010 Mar 9; 74(10): 798-806. Impact Factor:8.017 ViewExport to BibTeXExport to EndNote