Keywords: Circular Dichroism, Differential Scanning Calorimetry, Domain Swapping, Open And Closed Interface, Protein Aggregation, Structure-Stability Relationship, Dimer, Ribonuclease A, Alpha Helix, Amino Terminal Sequence, Article, Carboxy Terminal Sequence, Chemical Reaction Kinetics, Comparative Study, Correlation Analysis, Dissociation, Enzyme Structure, Priority Journal, Thermostability, Animals, Cattle, Dimerization, Enzyme Stability, Protein Denaturation, Protein Structure, Tertiary, Pancreatic,
Affiliations: *** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone 6, I-80134 Napoli, Italy
Dipartimento di Chimica Biologica, Universitá degli Studi di Napoli Federico II, via Mezzocannone 6, I-80134 Napoli, Italy
Dipartimento di Scienze Biologiche Ed Ambientali, Universitá del Sannio, Via Port'Arsa, 11, I-82100 Benevento, Italy
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Fruchter, R. G., Crestfield, A. M., Preparation and properties of two active forms of ribonuclease dimer (1965) J. Biol. Chem., 240, pp. 3868-3874
Liu, Y., Hart, P. J., Schlunegger, M. P., Eisenberg, D., The crystal structure of a 3D domain-swapped dimer of RNase a at 2. 1 resolution (1998) Proc. Natl. Acad. Sci. U. S. A., 95, pp. 3437-3442
Privalov, P. L., Stability of proteins: Small globular proteins (1979) Adv. Protein Chem., 33, pp. 167-241
Zhou, Y., Hall, C. K., Karplus, M., The calorimetric criterion for a two-state process revisited (1999) Protein Sci., 8, pp. 1064-1074
Yan, Y. B., Zhang, R. Q., Zhou, H. M., Biphasic reductive unfolding of ribonuclease a is temperature dependent (2002) Eur. J. Biochem., 269, pp. 5314-5322
Simons, E. R., Blout, E. R., Circular dichroism of ribonuclease A, ribonuclease S, and some fragments (1968) J. Biol. Chem., 243, pp. 218-221
Kraulis, P. J., A program to produce both detailed and schematic plots of protein structures (1991) J. Appl. Crystallogr., 24, pp. 946-950
Merritt, E. A., Murphy, M. E. P., Raster3D Version 2. 0-a program for photorealistic molecular graphics (1994) Acta Crystallogr., D Biol. Crystallogr., 50, pp. 869-873
On the thermal stability of the two dimeric forms of ribonuclease