Protective effect of carnosine during nitrosative stress in astroglial cell cultures(379 views) Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Keywords: Antioxidants, Carnosine, Heme Oxygenase, Mitochondria, Mt-Sod, Oxidative Stress, Gamma Interferon, Heat Shock Protein 32, Lipopolysaccharide, Nitric Oxide, Superoxide Dismutase, Animal Cell, Article, Astrocyte, Brain Mitochondrion, Cell Protection, Controlled Study, Drug Effect, Drug Mechanism, Nerve Degeneration, Neuroprotection, Nonhuman, Nucleotide Sequence, Priority Journal, Protein Modification, Upregulation, Base Sequence, Blotting, Western, Cultured, Dna Primers, Interferon Type Ii, Neuroprotective Agents, Nitrosation, Up-Regulation,
Affiliations: *** IBB - CNR ***
Department of Chemical Sciences, University of Catania, Italy
Department of Physiological Sciences, University of Catania, Italy
CNR Section of Catania, Institute of Neurological Sciences, Italy
Department of Internal Medicine, University of Catania, Italy
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Beal, M. F., Bioenergetic approaches for neuroprotection in Parkinson's disease (2003) Ann. Neurol., 53, pp. 39-4
Butterfield, D. A., Castegna, A., Drake, J., Scapagnini, G., Calabrese, V., Vitamin e and neurodegenerative disorders associated with oxidative stress (2002) Nutr. Neurosci., 5, pp. 229-239
Gegg, M. E., Beltran, B., Salas-Pino, S., Bolanos, J. P., Clark, J. B., Moncada, S., Heales, S. J., Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: Implications for neuroprotection/neurodegeneration? (2002) J. Neurochem., 86, pp. 228-237
Poon, H. F., Calabrese, V., Scapagnini, G., Butterfield, D. A., Free radicals and brain aging (2004) Clin. Geriatr. Med., 20, pp. 329-359
O'Dowd, J. J., Cairns, M. T., Trainor, M., Robins, D. J., Miller, D. J., Analysis of carnosine, homocarnosine, and other histidyl derivatives in rat brain (1990) J. Neurochem., 55, pp. 446-452
Hipkiss, A. R., Preston, J. E., Himsworth, D. T. M., Worthigton, V. C., Abbott, N. J., Protective effects of carnosine against malondialdehyde- induced toxicity towards cultured rat brain endothelial cells (1997) Neurosci. Lett., 283, pp. 135-138
Boldyrev, A. A., Song, R., Dyatlov, V., Lawrence, D., Carpenter, D., Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species (1999) Neuroscience, 94, pp. 571-577
Stvolinsky, S. L., Kukley, M. L., Dobrota, D., Matejovicova, M., Tkac, I., Boldyrev, A. A., Carnosine: An endogenous neuroprotector in the ischemic brain (1999) Cell. Mol. Neurobiol., 19, pp. 45-56
Stvolinskii, S. L., Fedorova, T. N., Yuneva, M. O., Boldyrev, A. A., Protective effect of carnosine on Cu, Zn-superoxide dismutase during impaired oxidative metabolism in the brain in vivo (2003) Bull. Exp. Biol. Med., 135, pp. 130-132
Decker, E. A., Livisay, S. A., Zhou, S., A re-evaluation of the antioxidant activity of purified carnosine (2000) Biochemistry (Moscow), 65, pp. 901-906
Kang, J. H., Kim, K. S., Choi, S. Y., Kwon, H. Y., Won, M. H., Kang, T. C., Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification (2002) Mol. Cells, 13, pp. 498-502
Bonomo, R. P., Bruno, V., Conte, E., De Guidi, G., La Mendola, D., MacCarrone, G., Nicoletti, F., Vecchio, G., Potentiometric, spectroscopic and antioxidant activity studies of SOD mimics containing carnosine (2003) Dalton Trans., pp. 4406-4415
Hipkiss, A. R., Brownson, C., Bertani, M. F., Ruiz, E., Ferro, A., Reaction of carnosine with aged proteins: Another protective process? (2002) Ann. NY Acad. Sci., 959, pp. 285-294
Hobart, L. J., Seibel, I., Yeargans, G. S., Seidler, N. W., Anti-crosslinking properties of carnosine: Significance of histidine (2004) Life Sci., 75, pp. 1379-1389
Warton, D. C., Tzagoloff, A., Cytochrome oxidase from bovine heart mitochondria (1967) Method Enzymol., 10, pp. 245-257
Schapira, A. H. V., Mann, V. M., Cooper, J. M., Dexter, D., Daniel, S. E., Jenner, P., Clark, J. B., Marsden, C. D., Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease (1990) J. Neurochem., 55, pp. 2142-2145
Genova, M. L., Pich, M. M., Pernacchia, A., Bianchi, C., Biondi, A., Bovina, C., Falasca, A. I., Lenaz, G., The mitochondrial production of reactive oxygen species in relation to aging and pathology (2004) Ann. NY Acad. Sci., 1011, pp. 86-100
Stewart, V. C., Heslegrave, A. J., Brown, G. C., Clark, J. B., Heales, S. J., Nitric oxide-dependent damage to neuronal mitochondria involves the NMDA receptor (2002) Eur. J. Neurosci., 15, pp. 458-464
Mosser, D. D., Morimoto, R. I., Molecular chaperones and the stress of oncogenesis (2004) Oncogene, 23, pp. 2907-2918
Maines, M. D., Heme oxygenase transgenic mice as a model to study neuroprotection (2002) Method Enzymol., 353, pp. 374-388
Hyun, D. H., Gray, D. A., Halliwell, B., Jenner, P., Interference with ubiquitination causes oxidative damage and increased protein nitration: Implications for neurodegenerative diseases (2004) J. Neurochem., 90, pp. 422-430
Severina, S. I., Bussygina, O. G., Pyatakova, N. V., Carnosine as a regulator of soluble guanylate cyclase (2000) Biochemistry (Moscow), 65, pp. 921-927
Reynolds, M. R., Berry, R. W., Binder, L. I., Site-Specific Nitration and Oxidative Dityrosine Bridging of the tau Protein by Peroxynitrite: Implications for Alzheimer's Disease (2005) Biochemistry., 44, pp. 1690-1700
Alam, J., Cook, J. L., Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway (2003) Curr. Pharm. Des., 9, pp. 2499-2511
Bonomo, R. P., Impellizzeri, G., La Mendola, D., Maccarrone, G., Pappalardo, G., Santoro, A. M., Tabb, G., Rizzarelli, E., Functional mimics of Cu-Zn Superoxide Dismutase Enzymes (2003) Metal-ligand Interactions in Nano-, Micro-, and Macro-systems in Complex Environments, pp. 41-63. , Russo N., Salahub D. R., and Witko M., (eds.), Kluwer, Dordrecht
Protective effect of carnosine during nitrosative stress in astroglial cell cultures
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