Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer (385 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004 Apr 15; 73(6): 689-695.
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Paper type: Journal Article,
Impact factor: 2.863, 5-year impact factor: 2.675
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-1942499483&partnerID=40&md5=57f01366b4a8730d3a22a3173d575cfb
Keywords: Ligand Binding, Population Shift, Protein Dynamics, Protein Structure-Function, Ribonucleases, Three-Dimensional Domain Swapping, X-Ray Diffraction, Complexation, Conformations, Crystal Structure, Enzyme Kinetics, Isomers, Molecular Structure, Biopolymers, Deoxycitidylyl (3, ) 2 Deoxyadenosine, Bovine Seminal Ribonuclease, Sulfate, Unclassified Drug, Article, Cattle, Chemical Binding, Conformational Transition, Disulfide Bond, Enzyme Structure, Animals, Binding Sites, Crystallography, Dimerization, Endoribonucleases, Models, Quaternary,
Affiliations:
*** IBB - CNR ***
Dipartimento di Chimica, Univ. Studi Napoli Federico II, Via Cynthia, 80126 Napoli, Italy
Dipto. di Scienze Farmaceutiche, Università di Salerno, Via ponte don Melillo, 84084, Fisciano (Sa), Italy
Ist. di Biostrutture e Bioimmagini, CNR, Via Mezzocannone 6, 80134 Napoli, Italy
References:
Bennet, A.M., Choe, S., Eisenberg, D., (1994) Proc Natl Acad Sci USA, 91, pp. 3127-313
Bennet, M.J., Schlunegger, M.P., Eisenberg, D., (1995) Protein Sci, 4, pp. 2455-2468
Schlunegger, M.P., Bennet, M.J., Eisenberg, D., (1997) Advances in Protein Chemistry, pp. 61-122. , Richards, F. M., Eisenberg, D. S., Kim, P. S., Eds.
Academic Press: New York
Newcomer, M.E., (2001) Nat Struct Biol, 8, pp. 282-284
Liu, Y., Eisenberg, D., (2002) Protein Sci, 11, pp. 1285-1299
Capasso, S., Giordano, F., Mattia, C.A., Mazzarella, L., Zagari, A., (1983) Biopolymers, 22, pp. 327-332
Mazzarella, L., Capasso, S., Demasi, D., Di Lorenzo, G., Mattia, C.A., Zagari, A., (1993) Acta Cryst D, 49, pp. 389-402
Di Donato, A., Piccoli, R., D'Alessio, G., (1987) Biochem J, 241, pp. 435-440
Piccoli, R., Di Donato, A., D'Alessio, G., (1988) Biochem J, 253, pp. 329-336
Piccoli, R., Tamburini, M., Piccialli, G., Di Donato, A., Parente, A., D'Alessio, G., (1992) Proc Natl Acad Sci USA, 89, pp. 1870-1874
Berisio, R., Sica, F., Di Lorenzo, C., Di Fiore, A., Piccoli, R., Mazzarella, L., (2003) FEBS Lett, 554, pp. 105-110
Di Donato, A., Cafaro, V., Romeo, I., D'Alessio, G., (1995) Protein Sci, 4, pp. 1470-1477
Ciglic, M.I., Jackson, P.J., Raillard, S.A., Haugg, M., Jermann, T.M., Opitz, J.G., Trabesinger-Ruf, N., Benner, S.A., (1998) Biochemistry, 37, pp. 4008-4022
Opitz, J.G., Ciglic, M.I., Haugg, M., Trautwein-Fritz, K., Raillard, S.A., Jerman, T.M., Benner, S.A., (1998) Biochemistry, 37, pp. 4023-4033
Crestfield, A.M., Stein, W.H., Moore, S., (1962) Arch Biochem Biophys, (SUPPL. 1), pp. 221-222
Liu, Y., Hart, P.J., Schlunegger, M.P., Eisenberg, D., (1998) Proc Natl Acad Sci USA, 95, pp. 3437-3442
Liu, Y., Gotte, G., Libonati, M., Eisenberg, D., (2001) Nat Struct Biol, 8, pp. 211-214
Vitagliano, L., Adinolfi, S., Sica, F., Merlino, A., Zagari, A., Mazzarella, L., (1999) J Mol Biol, 293, pp. 569-577
Kumar, S.M., Buyong, M., Tsai, C.J., Sinha, N., Nussinov, R., (2000) Protein Sci, 9, pp. 10-19
Ma, B., Kumar, S.M., Tsai, C.J., Nussinov, R., (1999) Protein Eng, 12, pp. 713-720
Koshland, D.E., (1958) Proc Natl Acad Sci USA, 44, pp. 98-123
Monod, J., Wyman, J., Cahngeux, J.P., (1965) J Mol Biol, 12, pp. 80-118
Sica, F., Adinolfi, A., Berisio, R., De Lorenzo, C., Mazzarella, L., Piccoli, R., Vitagliano, L., Zagari, A., (1999) J Cryst Growth, 196, pp. 305-312
Otwinowsky, Z., Minor, W., (1997) Methods Enzymol, 276, pp. 307-326
Brunger, A.T., (1992) X-PLOR Version 3.1: A System for X-Ray Crystallography and NMR, , Yale University Press, New Haven, CT
Jones, T.A., Zou, J.Y., Cowan, S.W., Kjeldgaard, M., (1991) Acta Cryst A, 47, pp. 110-119
Laskowski, R.A., MacArthur, M.W., Moss, M.D., Thornton, J.M., (1993) J Appl Crystallogr, 26, pp. 283-291
Hooft, R.W., Vriend, G., Sander, C., Abola, E.E., (1996) Nature, 381, p. 272
Campbell, R.L., Petsko, G.A., (1987) Biochemistry, 26, pp. 8579-8584
Wlodawer, A., Svenson, L.A., Sjolin, L., Gilliland, G.L., (1988) Biochemistry, 27, pp. 2705-2717
Leonidas, D.D., Shapiro, R., Irons, L.I., Russo, N., Acharya, K.R., (1997) Biochemistry, 36, pp. 5578-5588
Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L., (2000) Protein Sci, 9, pp. 1217-1225
Berisio, R., Lamzin, V.S., Sica, F., Wilson, K.S., Zagari, A., Mazzarella, L., (1999) J Mol Biol, 292, pp. 845-854
Esposito, L., Vitagliano, L., Sica, F., Sorrentino, G., Zagari, A., Mazzarella, L., (2000) J Mol Biol, 297, pp. 713-732
Borkakoti, N., Moss, D.S., Palmer, R.A., (1982) Acta Cryst B, 38, pp. 2210-2217
Gilliland, G., (1997) Ribonucleases: Structures and Functions, pp. 306-341. , Riordan, J. F., D'Alessio, G., Eds.
Sica, F., Di Fiore, A., Zagari, A., Mazzarella, L., (2003) Proteins, 52, pp. 263-271
Zegers, I., Maes, D., Dao-Thi, M.H., Poortmans, F., Palmer, R., Wyns, L., (1994) Protein Sci, 3, pp. 2322-2339
Radha Kishan, K.V., Chandra, N.R., Sudarsanakumar, C., Suguna, K., Vijayan, M., (1995) Acta Cryst D, 51, pp. 703-710
Sadasivan, C., Nagendra, H.G., Vijayan, M., (1998) Acta Cryst D, 54, pp. 1343-1352
Merlino, A., Vitagliano, L., Ceruso, M.A., Di Nola, A., Mazzarella, L., (2002) Biopolymers, 65, pp. 274-283
Volkman, B.F., Lipson, D., Wemmer, D.E., (2001) Science, 291, pp. 2429-2433
Stock, A., (1999) Nature, 400, pp. 221-222
Feher, V.A., Cavanagh, J., (1999) Nature, 400, pp. 289-290
Nevo, R., Stroth, C., Kienberger, F., Kaftan, D., Brumfeld, V., Elbaum, M., Reich, Z., Hinterdorfer, P., (2003) Nature Struct Biol, 10, pp. 553-557
Bennet, A. M., Choe, S., Eisenberg, D., (1994) Proc Natl Acad Sci USA, 91, pp. 3127-313
Bennet, M. J., Schlunegger, M. P., Eisenberg, D., (1995) Protein Sci, 4, pp. 2455-2468
Newcomer, M. E., (2001) Nat Struct Biol, 8, pp. 282-284
Ciglic, M. I., Jackson, P. J., Raillard, S. A., Haugg, M., Jermann, T. M., Opitz, J. G., Trabesinger-Ruf, N., Benner, S. A., (1998) Biochemistry, 37, pp. 4008-4022
Opitz, J. G., Ciglic, M. I., Haugg, M., Trautwein-Fritz, K., Raillard, S. A., Jerman, T. M., Benner, S. A., (1998) Biochemistry, 37, pp. 4023-4033
Crestfield, A. M., Stein, W. H., Moore, S., (1962) Arch Biochem Biophys, (SUPPL. 1), pp. 221-222
Liu, Y., Hart, P. J., Schlunegger, M. P., Eisenberg, D., (1998) Proc Natl Acad Sci USA, 95, pp. 3437-3442
Kumar, S. M., Buyong, M., Tsai, C. J., Sinha, N., Nussinov, R., (2000) Protein Sci, 9, pp. 10-19
Ma, B., Kumar, S. M., Tsai, C. J., Nussinov, R., (1999) Protein Eng, 12, pp. 713-720
Koshland, D. E., (1958) Proc Natl Acad Sci USA, 44, pp. 98-123
Brunger, A. T., (1992) X-PLOR Version 3. 1: A System for X-Ray Crystallography and NMR, , Yale University Press, New Haven, CT
Jones, T. A., Zou, J. Y., Cowan, S. W., Kjeldgaard, M., (1991) Acta Cryst A, 47, pp. 110-119
Laskowski, R. A., MacArthur, M. W., Moss, M. D., Thornton, J. M., (1993) J Appl Crystallogr, 26, pp. 283-291
Hooft, R. W., Vriend, G., Sander, C., Abola, E. E., (1996) Nature, 381, p. 272
Campbell, R. L., Petsko, G. A., (1987) Biochemistry, 26, pp. 8579-8584
Leonidas, D. D., Shapiro, R., Irons, L. I., Russo, N., Acharya, K. R., (1997) Biochemistry, 36, pp. 5578-5588
Radha Kishan, K. V., Chandra, N. R., Sudarsanakumar, C., Suguna, K., Vijayan, M., (1995) Acta Cryst D, 51, pp. 703-710
Volkman, B. F., Lipson, D., Wemmer, D. E., (2001) Science, 291, pp. 2429-2433
Feher, V. A., Cavanagh, J., (1999) Nature, 400, pp. 289-290
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004 Apr 15; 73(6): 689-695.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.863, 5-year impact factor: 2.675
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-1942499483&partnerID=40&md5=57f01366b4a8730d3a22a3173d575cfb
Keywords: Ligand Binding, Population Shift, Protein Dynamics, Protein Structure-Function, Ribonucleases, Three-Dimensional Domain Swapping, X-Ray Diffraction, Complexation, Conformations, Crystal Structure, Enzyme Kinetics, Isomers, Molecular Structure, Biopolymers, Deoxycitidylyl (3, ) 2 Deoxyadenosine, Bovine Seminal Ribonuclease, Sulfate, Unclassified Drug, Article, Cattle, Chemical Binding, Conformational Transition, Disulfide Bond, Enzyme Structure, Animals, Binding Sites, Crystallography, Dimerization, Endoribonucleases, Models, Quaternary,
Affiliations:
*** IBB - CNR ***
Dipartimento di Chimica, Univ. Studi Napoli Federico II, Via Cynthia, 80126 Napoli, Italy
Dipto. di Scienze Farmaceutiche, Università di Salerno, Via ponte don Melillo, 84084, Fisciano (Sa), Italy
Ist. di Biostrutture e Bioimmagini, CNR, Via Mezzocannone 6, 80134 Napoli, Italy
References:
Bennet, A.M., Choe, S., Eisenberg, D., (1994) Proc Natl Acad Sci USA, 91, pp. 3127-313
Bennet, M.J., Schlunegger, M.P., Eisenberg, D., (1995) Protein Sci, 4, pp. 2455-2468
Schlunegger, M.P., Bennet, M.J., Eisenberg, D., (1997) Advances in Protein Chemistry, pp. 61-122. , Richards, F. M., Eisenberg, D. S., Kim, P. S., Eds.
Academic Press: New York
Newcomer, M.E., (2001) Nat Struct Biol, 8, pp. 282-284
Liu, Y., Eisenberg, D., (2002) Protein Sci, 11, pp. 1285-1299
Capasso, S., Giordano, F., Mattia, C.A., Mazzarella, L., Zagari, A., (1983) Biopolymers, 22, pp. 327-332
Mazzarella, L., Capasso, S., Demasi, D., Di Lorenzo, G., Mattia, C.A., Zagari, A., (1993) Acta Cryst D, 49, pp. 389-402
Di Donato, A., Piccoli, R., D'Alessio, G., (1987) Biochem J, 241, pp. 435-440
Piccoli, R., Di Donato, A., D'Alessio, G., (1988) Biochem J, 253, pp. 329-336
Piccoli, R., Tamburini, M., Piccialli, G., Di Donato, A., Parente, A., D'Alessio, G., (1992) Proc Natl Acad Sci USA, 89, pp. 1870-1874
Berisio, R., Sica, F., Di Lorenzo, C., Di Fiore, A., Piccoli, R., Mazzarella, L., (2003) FEBS Lett, 554, pp. 105-110
Di Donato, A., Cafaro, V., Romeo, I., D'Alessio, G., (1995) Protein Sci, 4, pp. 1470-1477
Ciglic, M.I., Jackson, P.J., Raillard, S.A., Haugg, M., Jermann, T.M., Opitz, J.G., Trabesinger-Ruf, N., Benner, S.A., (1998) Biochemistry, 37, pp. 4008-4022
Opitz, J.G., Ciglic, M.I., Haugg, M., Trautwein-Fritz, K., Raillard, S.A., Jerman, T.M., Benner, S.A., (1998) Biochemistry, 37, pp. 4023-4033
Crestfield, A.M., Stein, W.H., Moore, S., (1962) Arch Biochem Biophys, (SUPPL. 1), pp. 221-222
Liu, Y., Hart, P.J., Schlunegger, M.P., Eisenberg, D., (1998) Proc Natl Acad Sci USA, 95, pp. 3437-3442
Liu, Y., Gotte, G., Libonati, M., Eisenberg, D., (2001) Nat Struct Biol, 8, pp. 211-214
Vitagliano, L., Adinolfi, S., Sica, F., Merlino, A., Zagari, A., Mazzarella, L., (1999) J Mol Biol, 293, pp. 569-577
Kumar, S.M., Buyong, M., Tsai, C.J., Sinha, N., Nussinov, R., (2000) Protein Sci, 9, pp. 10-19
Ma, B., Kumar, S.M., Tsai, C.J., Nussinov, R., (1999) Protein Eng, 12, pp. 713-720
Koshland, D.E., (1958) Proc Natl Acad Sci USA, 44, pp. 98-123
Monod, J., Wyman, J., Cahngeux, J.P., (1965) J Mol Biol, 12, pp. 80-118
Sica, F., Adinolfi, A., Berisio, R., De Lorenzo, C., Mazzarella, L., Piccoli, R., Vitagliano, L., Zagari, A., (1999) J Cryst Growth, 196, pp. 305-312
Otwinowsky, Z., Minor, W., (1997) Methods Enzymol, 276, pp. 307-326
Brunger, A.T., (1992) X-PLOR Version 3.1: A System for X-Ray Crystallography and NMR, , Yale University Press, New Haven, CT
Jones, T.A., Zou, J.Y., Cowan, S.W., Kjeldgaard, M., (1991) Acta Cryst A, 47, pp. 110-119
Laskowski, R.A., MacArthur, M.W., Moss, M.D., Thornton, J.M., (1993) J Appl Crystallogr, 26, pp. 283-291
Hooft, R.W., Vriend, G., Sander, C., Abola, E.E., (1996) Nature, 381, p. 272
Campbell, R.L., Petsko, G.A., (1987) Biochemistry, 26, pp. 8579-8584
Wlodawer, A., Svenson, L.A., Sjolin, L., Gilliland, G.L., (1988) Biochemistry, 27, pp. 2705-2717
Leonidas, D.D., Shapiro, R., Irons, L.I., Russo, N., Acharya, K.R., (1997) Biochemistry, 36, pp. 5578-5588
Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L., (2000) Protein Sci, 9, pp. 1217-1225
Berisio, R., Lamzin, V.S., Sica, F., Wilson, K.S., Zagari, A., Mazzarella, L., (1999) J Mol Biol, 292, pp. 845-854
Esposito, L., Vitagliano, L., Sica, F., Sorrentino, G., Zagari, A., Mazzarella, L., (2000) J Mol Biol, 297, pp. 713-732
Borkakoti, N., Moss, D.S., Palmer, R.A., (1982) Acta Cryst B, 38, pp. 2210-2217
Gilliland, G., (1997) Ribonucleases: Structures and Functions, pp. 306-341. , Riordan, J. F., D'Alessio, G., Eds.
Sica, F., Di Fiore, A., Zagari, A., Mazzarella, L., (2003) Proteins, 52, pp. 263-271
Zegers, I., Maes, D., Dao-Thi, M.H., Poortmans, F., Palmer, R., Wyns, L., (1994) Protein Sci, 3, pp. 2322-2339
Radha Kishan, K.V., Chandra, N.R., Sudarsanakumar, C., Suguna, K., Vijayan, M., (1995) Acta Cryst D, 51, pp. 703-710
Sadasivan, C., Nagendra, H.G., Vijayan, M., (1998) Acta Cryst D, 54, pp. 1343-1352
Merlino, A., Vitagliano, L., Ceruso, M.A., Di Nola, A., Mazzarella, L., (2002) Biopolymers, 65, pp. 274-283
Volkman, B.F., Lipson, D., Wemmer, D.E., (2001) Science, 291, pp. 2429-2433
Stock, A., (1999) Nature, 400, pp. 221-222
Feher, V.A., Cavanagh, J., (1999) Nature, 400, pp. 289-290
Nevo, R., Stroth, C., Kienberger, F., Kaftan, D., Brumfeld, V., Elbaum, M., Reich, Z., Hinterdorfer, P., (2003) Nature Struct Biol, 10, pp. 553-557
Bennet, A. M., Choe, S., Eisenberg, D., (1994) Proc Natl Acad Sci USA, 91, pp. 3127-313
Bennet, M. J., Schlunegger, M. P., Eisenberg, D., (1995) Protein Sci, 4, pp. 2455-2468
Newcomer, M. E., (2001) Nat Struct Biol, 8, pp. 282-284
Ciglic, M. I., Jackson, P. J., Raillard, S. A., Haugg, M., Jermann, T. M., Opitz, J. G., Trabesinger-Ruf, N., Benner, S. A., (1998) Biochemistry, 37, pp. 4008-4022
Opitz, J. G., Ciglic, M. I., Haugg, M., Trautwein-Fritz, K., Raillard, S. A., Jerman, T. M., Benner, S. A., (1998) Biochemistry, 37, pp. 4023-4033
Crestfield, A. M., Stein, W. H., Moore, S., (1962) Arch Biochem Biophys, (SUPPL. 1), pp. 221-222
Liu, Y., Hart, P. J., Schlunegger, M. P., Eisenberg, D., (1998) Proc Natl Acad Sci USA, 95, pp. 3437-3442
Kumar, S. M., Buyong, M., Tsai, C. J., Sinha, N., Nussinov, R., (2000) Protein Sci, 9, pp. 10-19
Ma, B., Kumar, S. M., Tsai, C. J., Nussinov, R., (1999) Protein Eng, 12, pp. 713-720
Koshland, D. E., (1958) Proc Natl Acad Sci USA, 44, pp. 98-123
Brunger, A. T., (1992) X-PLOR Version 3. 1: A System for X-Ray Crystallography and NMR, , Yale University Press, New Haven, CT
Jones, T. A., Zou, J. Y., Cowan, S. W., Kjeldgaard, M., (1991) Acta Cryst A, 47, pp. 110-119
Laskowski, R. A., MacArthur, M. W., Moss, M. D., Thornton, J. M., (1993) J Appl Crystallogr, 26, pp. 283-291
Hooft, R. W., Vriend, G., Sander, C., Abola, E. E., (1996) Nature, 381, p. 272
Campbell, R. L., Petsko, G. A., (1987) Biochemistry, 26, pp. 8579-8584
Leonidas, D. D., Shapiro, R., Irons, L. I., Russo, N., Acharya, K. R., (1997) Biochemistry, 36, pp. 5578-5588
Radha Kishan, K. V., Chandra, N. R., Sudarsanakumar, C., Suguna, K., Vijayan, M., (1995) Acta Cryst D, 51, pp. 703-710
Volkman, B. F., Lipson, D., Wemmer, D. E., (2001) Science, 291, pp. 2429-2433
Feher, V. A., Cavanagh, J., (1999) Nature, 400, pp. 289-290
Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
Bovine seminal ribonuclease (BS-RNase) is a unique member of the pancreatic-like ribonuclease superfamily. This enzyme exists as two conformational isomers with distinctive biological properties. The structure of the major isomer is characterized by the swapping of the N-terminal segment (M x M BS-RNase). In this article, the crystal structures of the ligand-free M x M BS-RNase and its complex with 2'-deoxycitidylyl(3',5')-2'-deoxyadenosine derived from isomorphous crystals have been refined. Interestingly, the comparison between this novel ligand-free form and the previously published sulfate-bound structure reveals significant differences. In particular, the ligand-free M x M BS-RNase is closer to the structure of M x M BS-RNase productive complexes than to the sulfate-bound form. These results reveal that M x M BS-RNase presents a remarkable flexibility, despite the structural constraints of the interchain disulfide bridges and swapping of the N-terminal helices. These findings have important implications to the ligand binding mechanism of M x M BS-RNase. Indeed, a population shift rather than a substrate-induced conformational transition may occur in the M x M BS-RNase ligand binding process. (C) 2004 Wiley Periodicals, Inc.
Bovine seminal ribonuclease (BS-RNase) is a unique member of the pancreatic-like ribonuclease superfamily. This enzyme exists as two conformational isomers with distinctive biological properties. The structure of the major isomer is characterized by the swapping of the N-terminal segment (M x M BS-RNase). In this article, the crystal structures of the ligand-free M x M BS-RNase and its complex with 2'-deoxycitidylyl(3',5')-2'-deoxyadenosine derived from isomorphous crystals have been refined. Interestingly, the comparison between this novel ligand-free form and the previously published sulfate-bound structure reveals significant differences. In particular, the ligand-free M x M BS-RNase is closer to the structure of M x M BS-RNase productive complexes than to the sulfate-bound form. These results reveal that M x M BS-RNase presents a remarkable flexibility, despite the structural constraints of the interchain disulfide bridges and swapping of the N-terminal helices. These findings have important implications to the ligand binding mechanism of M x M BS-RNase. Indeed, a population shift rather than a substrate-induced conformational transition may occur in the M x M BS-RNase ligand binding process. (C) 2004 Wiley Periodicals, Inc.
Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
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Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
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* The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer (328 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Nov 29; 587(23): 3755-3762.
Impact Factor: 3.341
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Tabbì G, Giuffrida A, Bonomo RP
* Determination Of Formal Redox Potentials In Aqueous Solution Of Copper(ii) Complexes With Ligands Having Nitrogen And Oxygen Donor Atoms And Comparisonwith Their Epr And Uv–vis Spectral Features (336 views)
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Impact Factor: 3.274
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Alcides Petruk A, Vergara A, Estrin D, Merlino A
* Molecular basis of the NO trans influence in quaternary T-state human hemoglobin: A computational study (408 views)
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Impact Factor: 3.341
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McNeill A, Wu RM, Tzen KY, Aguiar PC, Arbelo JM, Barone P, Bhatia K, Barsottini O, Bonifati V, Bostantjopoulou S, Bressan R, Cossu G, Cortelli P, Felicio A, Ferraz HB, Herrera J, Houlden H, Hoexter M, Isla C, Lees A, Lorenzo-Betancor O, Mencacci NE, Pastor P, Pappata S, Pellecchia MT, Silveria-Moriyama L, Varrone A, Foltynie T, Schapira AH
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Impact Factor: 3.534
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Sasaki T, Ito H, Kimura Y, Arakawa R, Takano H, Seki C, Kodaka F, Fujie S, Takahata K, Nogami T, Suzuki M, Fujiwara H, Takahashi H, Nakao R, Fukumura T, Varrone A, Halldin C, Nishikawa T, Suhara T
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Impact Factor: 5.774
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Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L
* Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (300 views)
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Impact Factor: 3.361
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D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D
* Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease (556 views)
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Impact Factor: 3.99
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Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J
* Extrastriatal dopamine D 2 receptor binding in Huntington's disease (477 views)
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Impact Factor: 5.88
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Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
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Impact Factor: 4.897
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Finnema SJ, Varrone A, Hwang TJ, Gulyas B, Pierson ME, Halldin C, Farde L
* Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain (360 views)
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Impact Factor: 2.925
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Alfieri A, Pasanisi F, Salzano S, Esposito L, Martone D, Tafuri D, Daniele A, Contaldo F, Sacchetti L, Zagari A, Buono P
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
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Impact Factor: 2.773
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Ruggiero A, Masullo M, Marasco D, Ruocco MR, Grimaldi P, Arcari P, Zagari A, Vitagliano L
* The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability (406 views)
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Impact Factor: 3.085
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Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F
* Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants (399 views)
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Impact Factor: 2.605
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Varrone A, Steiger C, Schou M, Takano A, Finnema SJ, Guilloteau D, Gulyas B, Halldin C
* In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand (571 views)
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Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F
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Marasco D, Perretta G, Sabatella M, Ruvo M
* Past and Future Perspectives of Synthetic Peptide Libraries (561 views)
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Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F
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Impact Factor: 4.146
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D'Auria S, Varriale A, Gonnelli M, Saviano M, Staiano M, Rossi M, Strambini GB
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Joszal V, Nagy Z, Osz K, Sanna D, Di Natale G, La Mendola D, Pappalardo G, Rizzarelli E, Sovago I
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Impact Factor: 2.654
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Picone D, Di Fiore A, Ercole C, Franzese M, Sica F, Tomaselli S, Mazzarella L
* The role of the hinge loop in domain swapping - The special case of bovine seminal ribonuclease (376 views)
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Impact Factor: 5.854
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Sica F, Di Fiore A, Merlino A, Mazzarella L
* Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease - An enzyme tailored to evade ribonuclease protein inhibitor (443 views)
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Impact Factor: 6.355
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Pedone E, Ren B, Ladenstein R, Rossi M, Bartolucci S
* Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus - A member of a novel protein family related to protein disulfide-isomerase (392 views)
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Aloj L, Caracò C, Panico M, Zannetti A, Del Vecchio S, Tesauro D, De Luca S, Arra C, Pedone C, Morelli G, Salvatore M
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Impact Factor: 5.362
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Merlino A, Vitagliano L, Ceruso MA, Mazzarella L
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Sica F, Di Fiore A, Zagari A, Mazzarella L
* The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative (355 views)
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Impact Factor: 4.313
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Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
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Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
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Impact Factor: 3.992
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Hirst WD, Abrahamsen B, Blaney FE, Calver AR, Aloj L, Price GW, Medhurst AD
* Differences In The Central Nervous System Distribution And Pharmacology Of The Mouse 5-Hydroxytryptamine-6 Receptor Compared With Rat And Human Receptors Investigated By Radioligand Binding, Site-Directed Mutagenesis, And Molecular Modeling (272 views)
Molecular Pharmacology, 2003; 64: 1295-1308.
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Merlino A, Vitagliano L, Ceruso M, Di Nola A, Mazzarella L
* Global and local motions in ribonuclease A: A molecular dynamics study (411 views)
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Impact Factor: 2.372
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Riccio A, Vitagliano L, Di Prisco G, Zagari A, Mazzarella L
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Impact Factor: 10.7
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Vitagliano L, Merlino A, Zagari A, Mazzarella L
* Reversible substrate-induced domain motions in ribonuclease (345 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2002 Jan 1; 46(1): 97-104.
Impact Factor: 4.096
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Aloj L, Panico M, Caracó C, Zannetti A, Del Vecchio S, Di Nuzzo C, Arra C, Morelli G, Tesauro D, De Luca S, Pedone C, Salvatore M
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Impact Factor: 2.372
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De Luca S, Tesauro D, Di Lello P, Fattorusso R, Saviano M, Pedone C, Morelli G
* Synthesis and solution characterization of a porphyrin-CCK8 conjugate (443 views)
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Impact Factor: 1.451
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Delforge J, Bottlaender M, Pappata S, Loc'h C, Syrota A
* Absolute quantification by positron emission tomography of the endogenous ligand (343 views)
J Cereb Blood Flow Metab (ISSN: 0271-678x), 2001 May; 21(5): 613-630.
Impact Factor: 5.477
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Orru S, Vitagliano L, Esposito L, Mazzarella L, Marino G, Ruoppolo M
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Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Dec; 9(12): 2577-2582.
Impact Factor: 3.869
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Esposito L, Vitagliano L, Zagari A, Mazzarella L
Experimental evidence for the correlation of bond distances in peptide groups detected in ultrahigh-resolution protein structures (301 views)
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Impact Factor: 2.442
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Esposito L, Vitagliano L, Zagari A, Mazzarella L
Pyramidalization of backbone carbonyl carbon atoms in proteins (451 views)
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Impact Factor: 3.869
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Vitagliano L, Merlino A, Zagari A, Mazzarella L
Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2 ', 5 ')guanosine (680 views)
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Impact Factor: 3.869
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Berisio R, Vitagliano L, Mazzarella L, Zagari A
Crystal Structure Of A Collagen-Like Polypeptide With Repeating Sequence Pro-Hyp-Gly At 1. 4 Ang Resolution: Implications For Collagen Hydration (437 views)
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Impact Factor: 2.405
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Vitagliano L, Adinolfi S, Sica F, Merlino A, Zagari A, Mazzarella L
A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease (384 views)
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Impact Factor: 5.501
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Fogliano V, Monti SM, Visconti A, Randazzo G, Facchiano AM, Colonna G, Ritieni A
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Vitagliano L, Adinolfi S, Riccio A, Sica F, Zagari A, Mazzarella L
Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2 ', 5 ')adenosine (465 views)
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Impact Factor: 4.44
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Adinolfi S, Piccoli R, Sica F, Mazzarella L
BS-RNase tetramers: An example of domain-swapped oligomers (421 views)
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Impact Factor: 3.504
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Bonomo RP, Marchelli R, Tabbì G
Study of H2O2 interaction with copper(II) complexes with diamino-diamide type ligands, diastereoisomeric dipeptides, and tripeptides (513 views)
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* A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping (491 views)
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Moreira M, Ruggiero A, Esposito L, Choi HG, Kim HJ, Berisio R
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Ruggiero A, Garcia-ortega L, Ragucci S, Russo R, Landi N, Berisio R, Di Maro A
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Autiero I, Ruvo M, Improta R, Vitagliano L
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Calvanese L, Caporale A, Focà G, Iaccarino E, Sandomenico A, Doti N, Apicella I, Incisivo GM, De Falco S, Falcigno L, D’auria G, Ruvo M
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Picone D, Donnarumma F, Ferraro G, Gotte G, Fagagnini A, Butera G, Donadelli M, Merlino A
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Romano M, Squeglia F, Berisio R
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Picone D, Donnarumma F, Ferraro G, Russo Krauss I, Fagagnini A, Gotte G, Merlino A
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Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
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Sica F, Pica A, Merlino A, Russo Krauss I, Ercole C, Picone D
* The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer (328 views)
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Impact Factor: 3.341
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Tabbì G, Giuffrida A, Bonomo RP
* Determination Of Formal Redox Potentials In Aqueous Solution Of Copper(ii) Complexes With Ligands Having Nitrogen And Oxygen Donor Atoms And Comparisonwith Their Epr And Uv–vis Spectral Features (336 views)
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Impact Factor: 3.274
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Alcides Petruk A, Vergara A, Estrin D, Merlino A
* Molecular basis of the NO trans influence in quaternary T-state human hemoglobin: A computational study (408 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Sep 2; 587(15): 2393-2398.
Impact Factor: 3.341
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McNeill A, Wu RM, Tzen KY, Aguiar PC, Arbelo JM, Barone P, Bhatia K, Barsottini O, Bonifati V, Bostantjopoulou S, Bressan R, Cossu G, Cortelli P, Felicio A, Ferraz HB, Herrera J, Houlden H, Hoexter M, Isla C, Lees A, Lorenzo-Betancor O, Mencacci NE, Pastor P, Pappata S, Pellecchia MT, Silveria-Moriyama L, Varrone A, Foltynie T, Schapira AH
* Dopaminergic Neuronal Imaging in Genetic Parkinson's Disease: Insights into Pathogenesis (461 views)
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Impact Factor: 3.534
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Sasaki T, Ito H, Kimura Y, Arakawa R, Takano H, Seki C, Kodaka F, Fujie S, Takahata K, Nogami T, Suzuki M, Fujiwara H, Takahashi H, Nakao R, Fukumura T, Varrone A, Halldin C, Nishikawa T, Suhara T
* Quantification of dopamine transporter in human brain using PET with 18F-FE-PE2I (574 views)
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Impact Factor: 5.774
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Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L
* Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (300 views)
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Impact Factor: 3.361
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D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D
* Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease (556 views)
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Impact Factor: 3.99
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Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J
* Extrastriatal dopamine D 2 receptor binding in Huntington's disease (477 views)
Hum Brain Mapp (ISSN: 1065-9471, 1097-0193electronic, 1065-9471linking), 2011 Oct; 32(10): 1626-1636.
Impact Factor: 5.88
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Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
* A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (835 views)
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Impact Factor: 4.897
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Finnema SJ, Varrone A, Hwang TJ, Gulyas B, Pierson ME, Halldin C, Farde L
* Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain (360 views)
Synapse (ISSN: 0887-4476), 2010 Jul; 64(7): 573-577.
Impact Factor: 2.925
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Alfieri A, Pasanisi F, Salzano S, Esposito L, Martone D, Tafuri D, Daniele A, Contaldo F, Sacchetti L, Zagari A, Buono P
* Functional analysis of melanocortin-4-receptor mutants identified in severely obese subjects living in Southern Italy (397 views)
Gene (ISSN: 0378-1119), 2010 Jun 1; 457(1-2): 35-41.
Impact Factor: 2.266
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (422 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Ruggiero A, Masullo M, Marasco D, Ruocco MR, Grimaldi P, Arcari P, Zagari A, Vitagliano L
* The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability (406 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2009 Dec; 77(4): 1004-1008.
Impact Factor: 3.085
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Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F
* Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants (399 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1029-1037.
Impact Factor: 2.605
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Varrone A, Steiger C, Schou M, Takano A, Finnema SJ, Guilloteau D, Gulyas B, Halldin C
* In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand (571 views)
Synapse (ISSN: 0887-4476), 2009 Oct; 63(10): 871-880.
Impact Factor: 2.557
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Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F
* Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant (354 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic, 0961-8368linking), 2009 Jan; 18(1): 50-57.
Impact Factor: 2.937
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Marasco D, Perretta G, Sabatella M, Ruvo M
* Past and Future Perspectives of Synthetic Peptide Libraries (561 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2008 Oct; 9(5): 447-467.
Impact Factor: 3.011
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Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F
* The buried diversity of bovine seminal ribonuclease: Shape and cytotoxicity of the swapped non-covalent form of the enzyme (546 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2008 Feb 15; 376(2): 427-437.
Impact Factor: 4.146
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D'Auria S, Varriale A, Gonnelli M, Saviano M, Staiano M, Rossi M, Strambini GB
* Tryptophan phosphorescence studies of the D-galactose/ D-glucose-binding protein from Escherichia coli provide a molecular portrait with structural and dynamics features of the protein (693 views)
J Proteome Res (ISSN: 1535-3893), 2007; 6(4): 1306-1312.
Impact Factor: 5.675
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Joszal V, Nagy Z, Osz K, Sanna D, Di Natale G, La Mendola D, Pappalardo G, Rizzarelli E, Sovago I
* Transition metal complexes of terminally protected peptides containing histidyl residues (515 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2006 Sep; 100(8): 1399-1409.
Impact Factor: 2.654
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Picone D, Di Fiore A, Ercole C, Franzese M, Sica F, Tomaselli S, Mazzarella L
* The role of the hinge loop in domain swapping - The special case of bovine seminal ribonuclease (376 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Apr 8; 280(14): 13771-13778.
Impact Factor: 5.854
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Sica F, Di Fiore A, Merlino A, Mazzarella L
* Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease - An enzyme tailored to evade ribonuclease protein inhibitor (443 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2004 Sep 27; 279(35): 36753-36760.
Impact Factor: 6.355
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Pedone E, Ren B, Ladenstein R, Rossi M, Bartolucci S
* Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus - A member of a novel protein family related to protein disulfide-isomerase (392 views)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print), 2004 Sep; 271(16): 3437-3448.
Impact Factor: 3.26
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Aloj L, Caracò C, Panico M, Zannetti A, Del Vecchio S, Tesauro D, De Luca S, Arra C, Pedone C, Morelli G, Salvatore M
* In vitro and in vivo evaluation of In-111-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (587 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2004 Mar; 45(3): 485-494.
Impact Factor: 5.362
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Merlino A, Vitagliano L, Ceruso MA, Mazzarella L
* Subtle functional collective motions in pancreatic-like ribonucleases: From ribonuclease A to angiogenin (386 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2003 Oct 1; 53(1): 101-110.
Impact Factor: 4.313
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Sica F, Di Fiore A, Zagari A, Mazzarella L
* The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative (355 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2003 Sep 1; 52(2): 263-271.
Impact Factor: 4.313
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Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (393 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
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Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (430 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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Hirst WD, Abrahamsen B, Blaney FE, Calver AR, Aloj L, Price GW, Medhurst AD
* Differences In The Central Nervous System Distribution And Pharmacology Of The Mouse 5-Hydroxytryptamine-6 Receptor Compared With Rat And Human Receptors Investigated By Radioligand Binding, Site-Directed Mutagenesis, And Molecular Modeling (272 views)
Molecular Pharmacology, 2003; 64: 1295-1308.
Impact Factor: 4.12
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Merlino A, Vitagliano L, Ceruso M, Di Nola A, Mazzarella L
* Global and local motions in ribonuclease A: A molecular dynamics study (411 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002 Nov 15; 65(4): 274-283.
Impact Factor: 2.372
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Riccio A, Vitagliano L, Di Prisco G, Zagari A, Mazzarella L
* The crystal structure of a tetrameric hemoglobin in a partial hemichrome state (553 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2002 Jul 23; 99(15): 9801-9806.
Impact Factor: 10.7
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Vitagliano L, Merlino A, Zagari A, Mazzarella L
* Reversible substrate-induced domain motions in ribonuclease (345 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2002 Jan 1; 46(1): 97-104.
Impact Factor: 4.096
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Aloj L, Panico M, Caracó C, Zannetti A, Del Vecchio S, Di Nuzzo C, Arra C, Morelli G, Tesauro D, De Luca S, Pedone C, Salvatore M
* Radiolabeling approaches for cholecystokinin B receptor imaging (496 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002; 66(6): 370-380.
Impact Factor: 2.372
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De Luca S, Tesauro D, Di Lello P, Fattorusso R, Saviano M, Pedone C, Morelli G
* Synthesis and solution characterization of a porphyrin-CCK8 conjugate (443 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2001 Jul; 7(7): 386-394.
Impact Factor: 1.451
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Delforge J, Bottlaender M, Pappata S, Loc'h C, Syrota A
* Absolute quantification by positron emission tomography of the endogenous ligand (343 views)
J Cereb Blood Flow Metab (ISSN: 0271-678x), 2001 May; 21(5): 613-630.
Impact Factor: 5.477
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Orru S, Vitagliano L, Esposito L, Mazzarella L, Marino G, Ruoppolo M
Effect of deamidation on folding of ribonuclease (388 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Dec; 9(12): 2577-2582.
Impact Factor: 3.869
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Esposito L, Vitagliano L, Zagari A, Mazzarella L
Experimental evidence for the correlation of bond distances in peptide groups detected in ultrahigh-resolution protein structures (301 views)
Protein Eng (ISSN: 0269-2139, 0269-2139print, 0269-2139linking), 2000 Dec; 13(12): 825-828.
Impact Factor: 2.442
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Esposito L, Vitagliano L, Zagari A, Mazzarella L
Pyramidalization of backbone carbonyl carbon atoms in proteins (451 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Oct; 9(10): 2038-2042.
Impact Factor: 3.869
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Vitagliano L, Merlino A, Zagari A, Mazzarella L
Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2 ', 5 ')guanosine (680 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Jun; 9(6): 1217-1225.
Impact Factor: 3.869
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Berisio R, Vitagliano L, Mazzarella L, Zagari A
Crystal Structure Of A Collagen-Like Polypeptide With Repeating Sequence Pro-Hyp-Gly At 1. 4 Ang Resolution: Implications For Collagen Hydration (437 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 8-13.
Impact Factor: 2.405
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Vitagliano L, Adinolfi S, Sica F, Merlino A, Zagari A, Mazzarella L
A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease (384 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 29; 293(3): 569-577.
Impact Factor: 5.501
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Fogliano V, Monti SM, Visconti A, Randazzo G, Facchiano AM, Colonna G, Ritieni A
Identification of a β-lactoglobulin lactosylation site (448 views)
Biochim Biophys Acta Protein Struct Mol Enzymol (ISSN: 0167-4838), 1998 Nov 10; 1388(2): 295-304.
Impact Factor: 1.687
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Vitagliano L, Adinolfi S, Riccio A, Sica F, Zagari A, Mazzarella L
Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2 ', 5 ')adenosine (465 views)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 1998 Sep; 7(8): 1691-1699.
Impact Factor: 4.44
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Adinolfi S, Piccoli R, Sica F, Mazzarella L
BS-RNase tetramers: An example of domain-swapped oligomers (421 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 1996 Dec 2; 398(2-3): 326-332.
Impact Factor: 3.504
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Bonomo RP, Marchelli R, Tabbì G
Study of H2O2 interaction with copper(II) complexes with diamino-diamide type ligands, diastereoisomeric dipeptides, and tripeptides (513 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Nov 15; 60(3): 205-218.
Impact Factor: 1.342
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54 Records (53 excluding Abstracts).
Total impact factor: 210.936 (207.402 excluding Abstracts).
Total 5 year impact factor: 205.418 (201.403 excluding Abstracts).
Total impact factor: 210.936 (207.402 excluding Abstracts).
Total 5 year impact factor: 205.418 (201.403 excluding Abstracts).
385 views. Last view on Friday 19 May 2023, 20:49:54
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