A-kinase anchor protein 84/121 are targeted to mitochondria and mitotic spindles by overlapping amino-terminal motifs(725 views) Cardone L, de Cristofaro T, Affaitati A, Garbi C, Ginsberg MD, Saviano M, Varrone S, Rubin CS, Gottesman ME, Avvedimento EV, Feliciello A
Keywords: A-Kinase Anchor Proteins, Mitochondria, Mitotic Spindles, S-Akap84 Akap121, Cyclic Amp Dependent Protein Kinase, Cyclic Amp Dependent Protein Kinase Anchoring Protein, Green Fluorescent Protein, Hybrid Protein, Isoprotein, Mutant Protein, Tissue Extract, Tubulin, Unclassified Drug, Amino Terminal Sequence, Animal Cell, Animal Cell Culture, Animal Tissue, Article, Cellular Distribution, Controlled Study, Deletion Mutant, Germ Cell, Immunohistochemistry, Immunoprecipitation, Interphase, Microtubule, Mitosis Spindle, Mouse, Nonhuman, Priority Journal, Protein Binding, Protein Domain, Protein Localization, Protein Motif, Protein Purification, Site Directed Mutagenesis, Testis, Adaptor Proteins, Signal Transducing, Amino Acid Motifs, Amino Acid Sequence, Base Sequence, Carrier Proteins, Cell Line, Cyclic Amp-Dependent Protein Kinases, Complementary, Membrane Proteins, Mitotic Spindle Apparatus, Molecular Sequence Data, Site-Directed, Recombinant Fusion Proteins, Sequence Deletion, Spermatozoa, Two-Hybrid System Techniques,
Affiliations: *** IBB - CNR ***
Dipartimento Di Biologia E Patologia Molecolare E Cellulare, BioGem Consortium, Universitá Federico II, via S. Pansini 5, 80131 Naples, Italy
Institute of Cancer Research, Columbia University, New York, NY 10032, United States
Centro Studi Biocristallografia CNR, via Mezzocannone 6, Naples, Italy
Department of Molecular Pharmacology, Atran Laboratories, Albert Einstein College of Medicine, Bronx, NY 10461, United States
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Rubin, C. S., A kinase anchor proteins and the intracellular targeting of signals carried by cyclic AMP (1994) Biochim. Biophys. Acta, 1224, pp. 467-479
Smith, F. D., Scott, J. D., Signaling complexes: Junctions on the intracellular information super highway (2002) Curr. Biol., 12, pp. R32-R40
Miki, K., Eddy, E. M., Single amino acids determine specificity of binding of protein kinase A regulatory subunits by protein kinase A anchoring proteins (1999) J. Biol. Chem., 274, pp. 29057-29062
Angelo, R. G., Rubin, C. S., Characterization of structural features that mediate the tethering of Caenorhabditis elegans protein kinase A to a novel A kinase anchor protein. Insights into the anchoring of PKAI isoforms (2000) J. Biol. Chem., 275, pp. 4351-4362
Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Hicks, J. B., Gallatin, W. M., Scott, J. D., Association of protein kinase A and protein phosphatase 2B with a common anchoring protein (1995) Science, 267, pp. 108-111
Klauck, T. M., Faux, M. C., Labudda, K., Langeberg, L. K., Jaken, S., Scott, J. D., Coordination of three signaling enzymes by AKAP79, a mammalian scaffold-protein (1996) Science, 271, pp. 1589-1592
Schillace, R. V., Scott, J. D., Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220 (1999) Curr. Biol., 9, pp. 321-324
Westphal, R. S., Tavalin, S. J., Lin, J. W., Alto, N. M., Fraser, I. D., Langeberg, L. K., Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex (1999) Science, 285, pp. 93-96
Steen, R. L., Martins, S. B., Tasken, K., Collas, P., Recruitment of protein phosphatase 1 to the nuclear envelope by A-kinase anchoring protein AKAP149 is a prerequisite for nuclear lamina assembly (2000) J. Cell Biol., 150, pp. 1251-1262
Lester, L. B., Langeberg, L. K., Scott, J. D., Anchoring of protein kinase A facilitates hormone-mediated insulin secretion (1997) Proc. Natl. Acad. Sci. USA, 94, pp. 14942-14947
Gray, P. C., Scott, J. D., Catterall, W. A., Regulation of ion channels by cAMP-dependent protein kinase and A-kinase anchoring proteins (1998) Curr. Opin. Neurobiol., 8, pp. 330-334
Westphal, R. S., Soderling, S. H., Alto, N. M., Langeberg, L. K., Scott, J. D., Scar/WAVE-1, a wiskott-aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold (2000) EMBO J., 19, pp. 4589-4600
Lester, L. B., Faux, M. C., Nauert, J. B., Scott, J. D., Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation (2001) Endocrinology, 142, pp. 1218-1227
Fink, M. A., Zakhary, D. R., Mackey, J. A., Desnoyer, R. W., Apperson-Hansen, C., Damron, D. S., Bond, M., AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes (2001) Circ. Res., 88, pp. 291-297
Lin, R., Moss, S. B., Rubin, C. S., Characterization of S-AKAP84, a novel developmentally regulated A kinase anchor protein of male germ cells (1995) J. Biol. Chem., 270, pp. 27804-27811
Huang, L. J., Durick, K., Weiner, J. A., Chun, J., Taylor, S. S., Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits (1997) J. Biol. Chem., 272, pp. 8057-8064
Huang, L. J., Wang, L., Ma, Y., Durick, K., Perkins, G., Deerinck, T. J., NH2-Terminal targeting motifs direct dual specificity A-kinase-anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum (1999) J. Cell Biol., 145, pp. 951-959
Kelley, L. A., MacCallum, R. M., Sternberg, M. J. E., Enhanced genome annotation using structural profiles in the program 3D-PSSM (2000) J. Mol. Biol., 299, pp. 499-520
Weisiger, R. A., Fridovich, I., Mitochondrial superoxide dismutase. Site of synthesis and intra-mitochondrial localization (1973) J. Biol. Chem., 24, pp. 4793-4796
Straight, A. F., Field, C. M., Microtubules, membranes and cytokinesis (2000) Curr. Biol., 10, pp. R760-R770
Downing, K. H., Nogales, E., New insights into microtubule structure and function from the atomic model of tubulin (1998) Eur. Biophys. J., 27, pp. 431-436
Rubino, H. M., Dammerman, M., Shafit-Zagardo, B., Erlichman, J., Localization and characterization of the binding site for the regulatory subunit of type II cAMP-dependent protein kinase on MAP2 (1989) Neuron, 3, pp. 631-638
Vallee, R. B., DiBartolomeis, M. J., Theurkauf, W. E., A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2) (1981) J. Cell Biol., 90, pp. 568-576
Wolkolwicz, M. J., Coonrod, S. M., Reddi, P. P., Millan, J. C., Hofmann, M. C., Herr, J. R., Refinement of the differentiated phenotype of the spermatogenic cell line GC-2spd (ts) (1996) Biol. Reprod., 55, pp. 923-932
Williams, R. C., Lee, J. C., Preparation of tubulin from brain (1982) Methods Enzymol., 85, pp. 376-408
A-kinase anchor protein 84/121 are targeted to mitochondria and mitotic spindles by overlapping amino-terminal motifs
Ciccarelli M, Sorriento D, Coscioni E, Iaccarino G, Santulli G * Adrenergic Receptors(271 views) Endocrinol Of The Heart In Health And Dis (ISSN: 9780-1280311249780128031117), 2016; N/D: 285-315. Impact Factor:0 ViewExport to BibTeXExport to EndNote