Dual-phase versus single-phase helical CT to detect and assess resectability of pancreatic carcinoma(356 views) Imbriaco M, Megibow AJ, Camera L, Pace L, Mainenti PP, Romano M, Selva G, Salvatore M
Am J Roentgenol (ISSN: 0361-803x), 2002 Jun; 178(6): 1473-1479.
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Diehl, S.J., Lehmann, K.J., Sadick, M., Lachmann, R., Georgi, M., Pancreatic cancer: Value of dual-phase helical CT in assessing resectability (1998) Radiology, 206, pp. 373-378
Hollet, M.D., Jorgensen, M.J., Jeffrey R.B., Jr., Quantitafive evaluation of pancreatic enhancement during dual-phase helical CT (1995) Radiology, 195, pp. 359-361
Baron, R.L., Understanding and optimizing use of contrast material for CT of the liver (1994) AJR, 163, pp. 323-331
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Boland, G.W., O'Malley, M.E., Saez, M., Fernandezdel-Castillo, C., Warshaw, A.L., Mueller, P.R., Pancreatic-phase versus portal vein-phase helical CT of the pancreas: Optimal temporal window for evaluation of pancreatic adenocarcinoma (1999) AJR, 172, pp. 605-608
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Farnell, M.B., Nagorney, D.M., Sarr, M.G., The Mayo clinic approach to the surgical treatment of adenocarcinoma of the pancreas (2001) Surg Clin North Am, 81, pp. 611-623
Keogan, M. T., McDermott, V. G., Paulson, E. K., Pancreatic malignancy: Effect of dual phase in tumor detection and vascular opacification (1997) Radiology, 205, pp. 513-518
Freeny, P. C., Traverso, L. W., Ryan, J. A., Diagnosis and staging of pancreatic adenocarcinoma with dynamic computed tomography (1993) Ant J Surg, 165, pp. 600-606
Choi, B. I., Chung, M. J., Han, J. K., Han, M. C., Yoon, Y. B., Detection of pancreatic adenocarcinoma: Relative value of arterial and late phases of spiral CT (1997) Abdom Imaging, 22, pp. 199-203
Lu, D. S., Vedantham, S., Krasny, R. M., Kadell, B., Berger, W. L., Reber, H. A., Two-phase helical CT for pancreatic tumors: Pancreatic versus hepatic phase enhancement of tumor, pancreas, and vascular structures (1996) Radiology, 199, pp. 697-701
Megibow, A. J., Pancreatic adenocarcinoma: Designing the examination to evaluate the clinical questions (1992) Radiology, 183, pp. 297-303
Kennedy, B. J., (1992) Manual for the staging of cancer, 4th ed., pp. 59-63. , Philadelphia: Lippincott
Zeman, R. K., Cooper, C., Zeiberg, A. S., TNM staging of pancreatic carcinoma using helical CT (1997) AJR, 169, pp. 459-464
Dupuy, D. E., Costello, P., Ecker, C. P., Spiral CT of the pancreas (1992) Radiology, 183, pp. 815-818
O'Malley, M. E., Boland, G. W., Wood, B. J., Fernandez-Del Castillo, C., Warshaw, A. L., Mueller, P. R., Adenocarcinoma of the head of the pancreas: Determination of surgical unresectability with thin-section pancreaticphase helical CT (1999) AJR, 173, pp. 1513-1518
Bluemke, D. A., Cameron, J. L., Hruban, R. H., Potentially resectable pancreatic adenocarcinoma: Spiral CT assessment with surgical and pathologic correlation (1995) Radiology, 197, pp. 381-385
Bonaldi, V. M., Bret, P. M., Atri, M., Garcia, P., Reinhold, C., A comparison of two injection protocols using helical and dynamic acquisitions in CT examinations of the pancreas (1996) AJR, 167, pp. 49-55
Diehl, S. J., Lehmann, K. J., Sadick, M., Lachmann, R., Georgi, M., Pancreatic cancer: Value of dual-phase helical CT in assessing resectability (1998) Radiology, 206, pp. 373-378
Hollet, M. D., Jorgensen, M. J., Jeffrey R. B., Jr., Quantitafive evaluation of pancreatic enhancement during dual-phase helical CT (1995) Radiology, 195, pp. 359-361
Baron, R. L., Understanding and optimizing use of contrast material for CT of the liver (1994) AJR, 163, pp. 323-331
Chambers, T. P., Baron, R. L., Lush, R. M., Hepatic CT enhancement, I. Alterations in the volume of contrast material within the same patients (1994) Radiology, 193, pp. 513-517
Boland, G. W., O'Malley, M. E., Saez, M., Fernandezdel-Castillo, C., Warshaw, A. L., Mueller, P. R., Pancreatic-phase versus portal vein-phase helical CT of the pancreas: Optimal temporal window for evaluation of pancreatic adenocarcinoma (1999) AJR, 172, pp. 605-608
McNulty, N. J., Francis, I. R., Platt, J. F., Cohan, R. H., Korobkin, M., Gebremariam, A., Multi-detector row helical CT of the pancreas: Effect of contrast-enhanced multiphasic imaging on enhancement of the pancreas, peripancreatic vasculature, and pancreatic adenocarcinoma (2001) Radiology, 220, pp. 97-102
Farnell, M. B., Nagorney, D. M., Sarr, M. G., The Mayo clinic approach to the surgical treatment of adenocarcinoma of the pancreas (2001) Surg Clin North Am, 81, pp. 611-623
Dual-phase versus single-phase helical CT to detect and assess resectability of pancreatic carcinoma
OBJECTIVE. The aim of this study was to compare dual-phase and single-phase helical CT for the detection and assessment of resectability of pancreatic adenocarcinoma. SUBJECTS AND METHODS. We studied 60 patients (31 men, 29 women; age range, 31-84 years; mean age, 62 years) with suspected pancreatic malignancy. Patients were randomly assigned to one of two groups. For group A (n = 30), unenhanced scans through the liver and pancreas were followed by two separate acquisitions (dual-phase) at 20-25 and at 60-80 sec after IV contrast administration. For group B (n = 30), unenhanced scans were followed by one set of scans (single-phase) acquired caudocranially (from the inferior hepatic margin to the diaphragm) starting 50 sec after IV contrast administration. Two observers independently scored images for the presence of tumor and for assessment of tumor resectability. RESULTS. Comparison of dual-phase versus single-phase helical CT for tumor detection showed a diagnostic accuracy for observer 1 of 87% and 90%, respectively, and for observer 2, of 90% and 87%, respectively. For both helical CT techniques, the overall agreement between the two observers was 83% (κ = 0.73 ± 0.03) for single-phase helical CT and 90% (κ = 0.89 ± 0.03) for dual-phase helical CT. The assessment of resectability was affected by the low number of resectable tumors (n = 8). CONCLUSION. Single-phase helical CT is effective for the diagnosis and assessment of resectability of patients with suspected pancreatic carcinoma. Advantages are the lower radiation dose and fewer images to film and store.
Dual-phase versus single-phase helical CT to detect and assess resectability of pancreatic carcinoma
Cusanno F, Cisbani E, Colilli S, Fratoni R, Garibaldi F, Giuliani F, Gricia M, Lucentini M, Magliozzi ML, Santarivenere F, Torrioli S, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, De Vincentis G, Scopinaro F * Results of clinical trials with SPEM(278 views) Nucl Instrum Methods Phys Res Sect A, 2007 Feb 1; 497(1): 46-50. Impact Factor:3.221 ViewExport to BibTeXExport to EndNote