Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: Comparison with sestamibi and Tl-201 scintigraphy
Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: Comparison with sestamibi and Tl-201 scintigraphy(307 views) Acampa W, Cuocolo A, Petretta M, Bruno A, Castellani M, Finzi A, Gerundini P
Nuclear Medicine Center of the National Council of Research (CNR), Department of Biomorphological and Functional Sciences, IRCCS Ospedale Maggiore, Milano, Italy
References: Braunwald, E., Rutherford, J.D., Reversible ischemic left ventricular dysfunction: Evidence for "hibernating myocardium (1986) J. Am. Coll. Cardiol., 8, pp. 1467-147
Bonow, R.O., Dilsizian, V., Cuocolo, A., Bacharach, S.L., Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose (1991) Circulation, 83, pp. 26-37
Beller, G.A., Ragosta, M., Extent of myocardial viability in regions of left ventricular dysfunction by rest-redistribution thallium-201 imaging: A powerful predictor of outcome (1998) J. Nucl. Cardiol., 5, pp. 445-448
Dilsizian, V., Bonow, R.O., Current diagnostic techniques of assessing myocardial viability in hibernating and stunned myocardium (1993) Circulation, 87, pp. 1-20
Kauffman, G.J., Boyne, T.S., Watson, D.D., Smith, W.H., Beller, G.A., Comparison of resting Tl-201 imaging and resting Tc-99m-sestamibi imaging for assessment of myocardial viability in patients with coronary artery disease and severe left ventricular dysfunction (1996) J. Am. Coll. Cardiol., 27, pp. 1592-1597
Dilsizian, V., Arrighi, J.A., Diodati, J.G., Quyyumi, A.A., Alavi, K., Bacharach, S.L., Myocardial viability in patients with chronic coronary artery disease. Comparison of 99mTc-sestamibi with thallium reinjection and [18F]fluorodeoxyglucose (1994) Circulation, 89, pp. 578-587
Udelson, E.J., Coleman, P.S., Metheral, J., Pandian, N.G., Gomez, A.R., Griffith, J.L., Predicting recovery of severe regional ventricular dysfunction. Comparison of resting scintigraphy with 201T1 and 99mTc-sestamibi (1994) Circulation, 89, pp. 2552-2561
Sciagrà, R., Santoro, G.M., Bisi, B., Pedenovi, P., Fazzini, P.F., Pupi, A., Rest-redistribution thallium-201 SPECT to detect myocardial viability (1998) J. Nucl. Med., 39, pp. 385-390
Pace, L., Perrone-Filardi, P., Mainenti, P.P., Cuocolo, A., Vezzuto, P., Varrone, A., Identification of viable myocardium in patients with chronic coronary artery disease using rest-redistribution thallium-201 tomography: Optimal image analysis (1998) J. Nucl. Med., 39, pp. 1869-1874
Maes, A.F., Borgers, M., Flameng, W., Nuyts, J.L., van de Werf, F., Ausma, J.J., Assessment of myocardial viability in chronic coronary artery disease using technetium-99m sestamibi SPECT. Correlation with histologic and positron emission tomography studies and functional follow-up (1997) J. Am. Coll. Cardiol., 29, pp. 62-68
Flamen, P., Bossuyt, A., Franken, P.R., Technetium-99m tetrofosmin in dipyridamole-stress myocardial SPECT imaging: Intraindividual comparison with technetium-99m sestamibi (1995) J. Nucl. Med., 36, pp. 2009-2015
Acampa, W., Cuocolo, A., Sullo, P., Varrone, A., Nicolai, E., Pace, L., Direct comparison of technetium 99m-sestamibi and technetium 99m-tetrofosmin cardiac single-photon emission computed tomography in patients with coronary artery disease (1998) J. Nucl. Cardiol., 5, pp. 265-274
Rigo, P., Leclercq, B., Itti, R., Lahiri, A., Braat, S., Technetium-99m tetrofosmin myocardial imaging: A comparison with thallium-201 and angiography (1994) J. Nucl. Med., 35, pp. 587-593
Matsunari, I., Fujino, S., Taki, J., Senma, J., Aoyama, T., Wakasugi, T., Quantitative rest technetium-99m tetrofosmin imaging in predicting functional recovery after coronary revascularization: Comparison with rest-redistribution thallium-201 (1997) J. Am. Coll. Cardiol., 29, pp. 1226-1233
Marwick, T., Willermart, B., D'Hondt, A.M., Baudhuin, T., Wijns, W., Detry, J.M., Selection of the optimal nonexercise stress for the evaluation of ischemic regional myocardial dysfunction and malperfusion: Comparison of dobutamine and adenosine using echocardiography and 99mTc-MIBI single computed tomography (1993) Circulation, 87, pp. 345-354
Kaul, S., Response of dysfunctional myocardium to dobutamine. The eyes see what the mind knows (1996) J. Am. Coll. Cardiol., 27, pp. 1608-1611
DePasquale, E.E., Nody, A.C., DePuey, G.E., Garcia, E.V., Pilcher, G., Bredlau, C., Quantitative rotational thallium-201 tomography for identifying and localizing coronary artery disease (1988) Circulation, 77, pp. 316-327
Sullo, P., Cuocolo, A., Nicolai, E., Cardei, S., Nappi, A., Squame, F., Quantitative exercise technetium-99m tetrofosmin myocardial tomography for the identification and localization of coronary artery disease (1996) Eur. J. Nucl. Med., 23, pp. 648-655
Nicolai, E., Cuocolo, A., Pace, L., Nappi, A., Sullo, P., Cardei, S., Adenosine coronary vasodilatation quantitative Tc-99m methoxy isobutyl isonitrile myocardial tomography in the identification and localization of coronary artery disease (1996) J. Nucl. Cardiol., 3, pp. 9-17
Petretta, M., Cuocolo, A., Bonaduce, D., Nicolai, E., Cardei, S., Berardino, S., Incremental prognostic value of thallium reinjection after stress-redistribution imaging in patients with previous myocardial infarction and left ventricular dysfunction (1997) J. Nucl. Med., 38, pp. 195-200
Hanley, J.A., McNeil, B.J., The meaning and use of the area under a receiver operating characteristic (ROC) curve (1982) Radiology, 143, pp. 29-36
Cohen, J., A coefficient of agreement for nominal scales (1960) Educ. Psychol. Meas., 20, pp. 37-46
Fleiss, J.L., (1981) Statistical Methods for Rates and Proportions, pp. 217-225. , 2nd ed. New York: John Wiley & Sons
Koplan, B.A., Beller, G.A., Ruiz, M., Yang, J.Y., Watson, D.D., Glover, D.K., Comparison between thallium-201 and technetium-99m-tetrofosmin uptake with sustained low flow and profound systolic dysfunction (1996) J. Nucl. Med., 37, pp. 1398-1402
Sansoy, V., Glover, D.K., Watson, D.D., Ruiz, M., Smith, W.H., Simanis, J.P., Comparison of thallium-201 resting redistribution with technetium-99m-sestamibi uptake and functional response to dobutamine for assessment of myocardial viability (1995) Circulation, 92, pp. 994-1004
Maublant, J.C., Marcaggi, X., Lusson, J.R., Boire, J.Y., Cauvin, J.C., Jacob, P., Comparison between thallium-201 and technetium-99m methoxy-isobutyl isonitrile defect size in single-photon emission computed tomography at rest, exercise and redistribution in coronary artery disease (1992) Am. J. Cardiol., 69, pp. 183-187
Cuocolo, A., Acampa, W., Nicolai, E., Pace, L., Petretta, M., Salvatore, M., Quantitative thallium-201 and technetium-99m sestamibi tomography at rest in detection of myocardial viability in patients with chronic ischemic left ventricular dysfunction (2000) J. Nucl. Cardiol., 7, pp. 8-15
Bonow, R. O., Dilsizian, V., Cuocolo, A., Bacharach, S. L., Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose (1991) Circulation, 83, pp. 26-37
Beller, G. A., Ragosta, M., Extent of myocardial viability in regions of left ventricular dysfunction by rest-redistribution thallium-201 imaging: A powerful predictor of outcome (1998) J. Nucl. Cardiol., 5, pp. 445-448
Kauffman, G. J., Boyne, T. S., Watson, D. D., Smith, W. H., Beller, G. A., Comparison of resting Tl-201 imaging and resting Tc-99m-sestamibi imaging for assessment of myocardial viability in patients with coronary artery disease and severe left ventricular dysfunction (1996) J. Am. Coll. Cardiol., 27, pp. 1592-1597
Udelson, E. J., Coleman, P. S., Metheral, J., Pandian, N. G., Gomez, A. R., Griffith, J. L., Predicting recovery of severe regional ventricular dysfunction. Comparison of resting scintigraphy with 201T1 and 99mTc-sestamibi (1994) Circulation, 89, pp. 2552-2561
Sciagr, R., Santoro, G. M., Bisi, B., Pedenovi, P., Fazzini, P. F., Pupi, A., Rest-redistribution thallium-201 SPECT to detect myocardial viability (1998) J. Nucl. Med., 39, pp. 385-390
Maes, A. F., Borgers, M., Flameng, W., Nuyts, J. L., van de Werf, F., Ausma, J. J., Assessment of myocardial viability in chronic coronary artery disease using technetium-99m sestamibi SPECT. Correlation with histologic and positron emission tomography studies and functional follow-up (1997) J. Am. Coll. Cardiol., 29, pp. 62-68
DePasquale, E. E., Nody, A. C., DePuey, G. E., Garcia, E. V., Pilcher, G., Bredlau, C., Quantitative rotational thallium-201 tomography for identifying and localizing coronary artery disease (1988) Circulation, 77, pp. 316-327
Hanley, J. A., McNeil, B. J., The meaning and use of the area under a receiver operating characteristic (ROC) curve (1982) Radiology, 143, pp. 29-36
Fleiss, J. L., (1981) Statistical Methods for Rates and Proportions, pp. 217-225. , 2nd ed. New York: John Wiley & Sons
Koplan, B. A., Beller, G. A., Ruiz, M., Yang, J. Y., Watson, D. D., Glover, D. K., Comparison between thallium-201 and technetium-99m-tetrofosmin uptake with sustained low flow and profound systolic dysfunction (1996) J. Nucl. Med., 37, pp. 1398-1402
Maublant, J. C., Marcaggi, X., Lusson, J. R., Boire, J. Y., Cauvin, J. C., Jacob, P., Comparison between thallium-201 and technetium-99m methoxy-isobutyl isonitrile defect size in single-photon emission computed tomography at rest, exercise and redistribution in coronary artery disease (1992) Am. J. Cardiol., 69, pp. 183-187
Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: Comparison with sestamibi and Tl-201 scintigraphy
Background. Technetium 99m tetrofosmin has been introduced as a myocardial perfusion agent, providing similar results to those of thallium 201 and sestamibi in the identification of patients with coronary artery disease. No data are available comparing tetrofosmin and sestamibi imaging in the identification of reversible left ventricular (LV) dysfunction in the same patients. This study compared the results of tetrofosmin, thallium, and sestamibi single photon emission computed tomography at rest in detection of myocardial viability in patients with previous myocardial infarction. Methods and Results. Seventeen patients with previous myocardial infarction who were undergoing coronary revascularization were studied. Echocardiography was performed at baseline and 3 months after revascularization to evaluate recovery of LV function. The optimal threshold cutoffs to separate reversible from irreversible dysfunction, as determined by receiver operating characteristic analysis, were 55% of peak activity for both tetrofosmin and sestamibi and 60% for thallium. In all asynergic segments (n = 77) analyzed, tetrofosmin uptake correlated with both sestamibi (r = 0.90, P < .0001) and thallium (r = 0.85, P < .0001) activity. The sensitivity and specificity for reversible dysfunction were, respectively, 70% and 70% for tetrofosmin, 70% and 66% for sestamibi, and 60% and 68% for thallium imaging (all P = not significant). The areas under the receiver operating characteristic curves constructed for tetrofosmin, thallium, and sestamibi activity were 0.74 ± 0.06 (mean ± SD), 0.75 ± 0.06, and 0.74 ± 0.06, respectively (all P = not significant). Concordance for detecting myocardial viability between tetrofosmin and thallium imaging was found in 67 regions (87%) (κ = 0.74), and concordance between tetrofosmin and sestamibi imaging was found in 69 regions (90%) (κ = 0.79). Conclusions. The diagnostic performance of quantitative rest tetrofosmin single photon emission computed tomography in predicting functional recovery after revascularization is comparable to that of both thallium and sestamibi scintigraphy in patients with myocardial infarction and chronic LV dysfunction.
Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: Comparison with sestamibi and Tl-201 scintigraphy
Tetrofosmin imaging in the detection of myocardial viability in patients with previous myocardial infarction: Comparison with sestamibi and Tl-201 scintigraphy
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R * 3. 0 T perfusion MR imaging(694 views) Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812. Impact Factor:0.023 ViewExport to BibTeXExport to EndNote