Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks (443 views) (PDF restricted 309 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2002 Nov; 29(11): 1447-1454.
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Paper type: Journal Article, Clinical Trial, Comparative Study, Controlled Clinical Trial, Research Support, Non-U. S. Gov'T,
Impact factor: 3.568, 5-year impact factor: 4.728
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036033630&partnerID=40&md5=1ec68a15cc54722122141f08c264a8ff
Keywords: Alzheimer, S Disease, Cerebral Perfusion, Frontotemporal Dementia, Spet, Statistical Parametric Mapping, Hexamethylpropylene Amine Oxime Technetium Tc 99m, Diagnostic Agent, Radiopharmaceutical Agent, Adult, Alzheimer Disease, Article, Behavior, Brain Blood Flow, Brain Cortex, Brain Region, Cingulate Gyrus, Clinical Article, Cognitive Defect, Controlled Study, Diagnostic Imaging, Diagnostic Procedure, Differential Diagnosis, Emotion, Female, Frontal Cortex, Human, Image Analysis, Nerve Cell Network, Occipital Cortex, Orbital Cortex, Parietal Lobe, Prefrontal Cortex, Single Photon Emission Computer Tomography, Statistical Parameters, Temporal Cortex, Brain Circulation, Clinical Trial, Comparative Study, Computer Assisted Diagnosis, Controlled Clinical Trial, Image Subtraction, Methodology, Pathophysiology, Scintiscanning, Three Dimensional Imaging, Vascularization, Cerebral Cortex, Cerebrovascular Circulation, Image Interpretation, Computer-Assisted, Three-Dimensional, Nerve Net, Subtraction Technique, Technetium Tc 99m Exametazime, Emission-Computed, Single-Photon, Alzheimer Disease Physiopathology Radionuclide Imaging, Cerebral Cortex Blood Supply Physiopathology Radionuclide Imaging, Dementia Physiopathology Radionuclide Imaging, Computer-Assisted Methods, Three-Dimensional Methods, Nerve Net Blood Supply Radionuclide Imaging, Radiopharmaceuticals Diagnostic Use, Technetium Tc 99m Exametazime Diagnostic Use, Single-Photon Methods,
Affiliations:
*** IBB - CNR ***
Biostructure and Bioimaging Institute, National Research Council, Via S. Pansini 5, 80131 Napoli, Italy. andrea.varrone@mailcmn.area.na.cnr.it
Faculty of Motor Sciences, University Parthenope, Napoli, Italy
Institute of Experimental Medicine and Biotechnology, Piano Lago Mangone (Cosenza), Italy
Department of Clinical and Experimental Medicine, University Federico II of Napoli, Italy
Department of Biomorphological and Functional Sciences, University Federico II of Napoli, Italy
References:
Francis, P.T., Holmes, C., Webster, M.T., Stratmann, G.C., Procter, A.W., Bowen, D.M., Preliminary neurochemical findings in non-Alzheimer dementia due to lobar atrophy (1993) Dementia, 4, pp. 172-17
Procter, A.W., Qurne, M., Francis, P.T., Neurochemical features of frontotemporal dementia (1999) Dement Geriatr Cogn Disord, 10 (SUPPL. 1), pp. 80-84
Litvan, I., Therapy and management of frontal lobe dementia patients (2001) Neurology, 56, pp. S41-S45
Miller, B.L., Ikonte, C., Ponton, M., Levy, M., Boone, K., Darby, A., Berman, N., Cummings, J.L., A study of the Lund-Manchester research criteria for frontotemporal dementia: Clinical and single-photon emission CT correlations (1997) Neurology, 48, pp. 937-942
Mathuranath, P.S., Nestor, P.J., Berrios, G.E., Rakowicz, W., Hodges, J.R., A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia (2000) Neurology, 55, pp. 1613-1620
Siri, S., Benaglio, I., Frigerio, A., Binetti, G., Cappa, S.F., A brief neuropsychological assessment for the differential diagnosis between frontotemporal dementia and Alzheimer's disease (2001) Eur J Neurol, 8, pp. 125-132
Starkstein, S.E., Migliorelli, R., Tesón, A., Sabe, L., Vázquez, S., Turjanski, M., Robinson, R.G., Leiguarda, R., Specificity of changes in cerebral blood flow in patients with frontal lobe dementia (1994) J Neurol Neurosurg Psychiatry, 57, pp. 790-796
Talbot, P.R., Lloyd, J.J., Snowden, J.S., Neary, D., Testa, H.J., A clinical role for 99mTc-HMPAO SPECT in the investigation of dementia? (1998) J Neurol Neurosurg Psychiatry, 64, pp. 306-313
Duara, R., Barker, W., Luis, C.A., Frontotemporal dementia and Alzheimer's disease: Differential diagnosis (1999) Dement Geriatr Cogn Disord, 10 (SUPPL. 1), pp. 37-42
Sjogren, M., Gustafson, L., Wikkelso, C., Wallin, A., Frontotemporal dementia can be distinguished from Alzheimer's disease and subcortical white matter dementia by an anterior-to-posterior rCBF-SPET ratio (2000) Dement Geriatr Cogn Disord, 11, pp. 275-285
Charpentier, P., Lavenu, I., Defebvre, L., Duhamel, A., Lecouffe, P., Pasquier, F., Steinling, M., Alzheimer's disease and frontotemporal dementia are differentiated by discriminant analysis applied to 99mTc HmPAO SPECT data (2000) J Neurol Neurosurg Psychiatry, 69, pp. 661-663
Holman, B.L., Johnson, K.A., Gerada, B., Carvalho, P.A., Satlin, A., The scintigraphic appearance of Alzheimer's disease: A prospective study using technetium-99m-HMPAO SPECT (1992) J Nucl Med, 33, pp. 181-185
Waldemar, G., Bruhn, P., Kristensen, M., Johnsen, A., Paulson, O.B., Lassen, N.A., Heterogeneity of neocortical cerebral blood flow deficits in dementia of the Alzheimer type: A [99mTc]-d,l-HMPAO SPECT study (1994) J Neurol Neurosurg Psychiatry, 57, pp. 285-295
Julin, P., Wahlund, L.O., Basun, H., Persson, A., Mare, K., Rudberg, U., Clinical diagnosis of frontal lobe dementia and Alzheimer's disease: Relation to cerebral perfusion, brain atrophy and electroencephalography (1995) Dementia, 6, pp. 142-147
Ishii, K., Sakamoto, S., Sasaki, M., Kitagaki, H., Yamaji, S., Hashimoto, M., Imamaura, T., Mori, E., Cerebral glucose metabolism in patients with frontotemporal dementia (1998) J Nucl Med, 39, pp. 1875-1878
Acton, P.D., Friston, K.J., Statistical parametric mapping in functional neuroimaging: Beyond PET and fMRI activation studies (1998) Eur J Nucl Med, 25, pp. 663-667
Imran, M.B., Kawashima, R., Awata, S., Sato, K., Kinomura, S., Ono, S., Yoshioka, S., Fukuda, H., Parametric mapping of cerebral blood flow deficits in Alzheimer's disease: A SPECT study using HMPAO and image standardization technique (1999) J Nucl Med, 40, pp. 244-249
Holmes, A., Poline, J.B., Friston, K.J., Characterising brain images with the general linear model (1997) Human brain function, pp. 59-84. , Frackowiak RSJ, ed. San Diego: Academic Press
Garraux, G., Salmon, E., Degueldre, C., Lemaire, C., Laureys, S., Franck, G., Comparison of impaired subcortico-frontal metabolic networks in normal aging, subcortico-frontal dementia, and cortical frontal dementia (1999) Neuroimage, 10, pp. 149-162
Clinical and neuropathological criteria for frontotemporal dementia (1994) J Neurol Neurosurg Psychiatry, 57, pp. 416-418. , The Lund and Manchester groups
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., Stadlan, E.M., Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease (1984) Neurology, 34, pp. 939-944
Chang, L.T., A method for attenuation correction in radionuclide computed tomography (1978) IEEE Trans Nucl Sci, 25, pp. 638-643
Pickut, B.A., Saerens, J., Mariën, P., Borggreve, F., Goeman, J., Vandevivere, J., Vervaet, A., De Deyn, P.P., Discriminative use of SPECT in frontal lobe-type dementia versus (senile) dementia of the Alzheimer's type (1997) J Nucl Med, 38, pp. 929-934
Ishii, K., Sasaki, M., Yamaji, S., Sakamoto, S., Kitagaki, H., Mori, E., Demonstration of decreased posterior cingulate perfusion in mild Alzheimer's disease by means of H2 15O positron emission tomography (1997) Eur J Nucl Med, 24, pp. 670-673
Salmon, E., Van der Linden, M.V., Franck, G., Anterior cingulate and motor network metabolic impairment in progressive supranuclear palsy (1997) Neuroimage, 5, pp. 173-178
Salmon, E., Collette, F., Degueldre, C., Lemaire, C., Franck, G., Voxel-based analysis of confounding effects of age and dementia severity on cerebral metabolism in Alzheimer's disease (2000) Hum Brain Mapping, 10, pp. 39-48
Pagani, M., Salmaso, D., Ramstrom, C., Jonsson, C., Lundqvist, R., Thurfjell, L., Schnell, P.D., Larsson, S.A., Mapping pathological (99m)Tc-d,l-hexamethylpropylene amine oxime uptake in Alzheimer's disease and frontal lobe dementia with SPECT (2001) Dement Geriatr Cogn Disord, 12, pp. 177-184
Mann, D.M., South, P.W., Snowden, J.S., Neary, D., Dementia of frontal lobe type: Neuropathology and immunohistochemistry (1993) J Neurol Neurosurg Psychiatry, 56, pp. 605-614
Sarazin, M., Pillon, B., Giannakopoulos, P., Rancurel, G., Samson, Y., Dubois, B., Clinicometabolic dissociation of cognitive functions and social behavior in frontal lobe lesions (1998) Neurology, 51, pp. 142-148
Devinsky, O., Morrell, M.J., Vogt, B.A., Contributions of anterior cingulate cortex to behaviour (1995) Brain, 118, pp. 279-306
Silberman, E.K., Weingartner, H., Hemispheric lateralization of functions related to emotion (1986) Brain Cogn, 5, pp. 322-353
Kawasaki, H., Kaufman, O., Damasio, H., Damasio, A.R., Granner, M., Bakken, H., Hori, T., Adolphs, R., Single-neuron responses to emotional visual stimuli recorded in human ventral prefrontal cortex (2001) Nat Neurosci, 4, pp. 15-16
Mychack, P., Kramer, J.H., Boone, K.B., Miller, B.L., The influence of right frontotemporal dysfunction on social behavior in frontotemporal dementia (2001) Neurology, 56, pp. S11-S15
Bonte, F.J., Hom, J., Tintner, R., Weiner, M.F., Single photon tomography in Alzheimer's disease and the dementias (1990) Semin Nucl Med, 20, pp. 342-352
O'Brien, J.T., Eagger, S., Syed, G.M., Sahakian, B.J., Levy, R., A study of regional cerebral blood flow and cognitive performance in Alzheimer's disease (1992) J Neurol Neurosurg Psychiatry, 55, pp. 1182-1187
Karbe, H., Kertesz, A., Davis, J., Kemp, B.J., Prato, F.S., Nicholson, R.L., Quantification of functional deficit in Alzheimer's disease using a computer-assisted mapping program for 99mTc-HMPAO SPECT (1994) Neuroradiology, 36, pp. 1-6
Osimani, A., Ichise, M., Chung, D.G., Pogue, J.M., Freedman, M., SPECT for differential diagnosis of dementia and correlation of rCBF with cognitive impairment (1994) Can J Neurol Sci, 21, pp. 104-111
Baron, J.C., Chetelat, G., Desgranges, B., Perchey, G., Landeau, B., De Sayette, V., Eustache, F., In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease (2001) Neuroimage, 14, pp. 298-309
Ebmeier, K.P., Glabus, M.F., Prentice, N., Ryman, A., Goodwin, G.M., A voxel-based analysis of cerebral perfusion in dementia and depression of old age (1998) Neuroimage, 7, pp. 199-208
Bouilleret, V., Dupont, S., Spelle, L., Baulac, M., Samson, Y., Semah, F., Insular cortex involvement in mesiotemporal lobe epilepsy: A positron emission tomography study (2002) Ann Neurol, 51, pp. 202-208
Frisoni, G., Beltramello, A., Geroldi, C., Weiss, C., Bianchetti, A., Trabucchi, M., Brain atrophy in frontotemporal dementia (1996) J Neurol Neurosurg Psychiatry, 61, pp. 157-165
Hodges, J., Frontotemporal dementia (Pick's disease): Clinical features and assessment (2001) Neurology, 56, pp. S6-S10
Signorini, M., Paulesu, E., Friston, K., Perani, D., Colleluori, A., Lucignani, G., Grassi, F., Fazio, F., Rapid assessment of regional cerebral metabolic abnormalities in single subjects with quantitative and nonquantitative [18F]FDG PET: A clinical validation of statistical parametric mapping (1999) Neuroimage, 9, pp. 63-80
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2002 Nov; 29(11): 1447-1454.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Clinical Trial, Comparative Study, Controlled Clinical Trial, Research Support, Non-U. S. Gov'T,
Impact factor: 3.568, 5-year impact factor: 4.728
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0036033630&partnerID=40&md5=1ec68a15cc54722122141f08c264a8ff
Keywords: Alzheimer, S Disease, Cerebral Perfusion, Frontotemporal Dementia, Spet, Statistical Parametric Mapping, Hexamethylpropylene Amine Oxime Technetium Tc 99m, Diagnostic Agent, Radiopharmaceutical Agent, Adult, Alzheimer Disease, Article, Behavior, Brain Blood Flow, Brain Cortex, Brain Region, Cingulate Gyrus, Clinical Article, Cognitive Defect, Controlled Study, Diagnostic Imaging, Diagnostic Procedure, Differential Diagnosis, Emotion, Female, Frontal Cortex, Human, Image Analysis, Nerve Cell Network, Occipital Cortex, Orbital Cortex, Parietal Lobe, Prefrontal Cortex, Single Photon Emission Computer Tomography, Statistical Parameters, Temporal Cortex, Brain Circulation, Clinical Trial, Comparative Study, Computer Assisted Diagnosis, Controlled Clinical Trial, Image Subtraction, Methodology, Pathophysiology, Scintiscanning, Three Dimensional Imaging, Vascularization, Cerebral Cortex, Cerebrovascular Circulation, Image Interpretation, Computer-Assisted, Three-Dimensional, Nerve Net, Subtraction Technique, Technetium Tc 99m Exametazime, Emission-Computed, Single-Photon, Alzheimer Disease Physiopathology Radionuclide Imaging, Cerebral Cortex Blood Supply Physiopathology Radionuclide Imaging, Dementia Physiopathology Radionuclide Imaging, Computer-Assisted Methods, Three-Dimensional Methods, Nerve Net Blood Supply Radionuclide Imaging, Radiopharmaceuticals Diagnostic Use, Technetium Tc 99m Exametazime Diagnostic Use, Single-Photon Methods,
Affiliations:
*** IBB - CNR ***
Biostructure and Bioimaging Institute, National Research Council, Via S. Pansini 5, 80131 Napoli, Italy. andrea.varrone@mailcmn.area.na.cnr.it
Faculty of Motor Sciences, University Parthenope, Napoli, Italy
Institute of Experimental Medicine and Biotechnology, Piano Lago Mangone (Cosenza), Italy
Department of Clinical and Experimental Medicine, University Federico II of Napoli, Italy
Department of Biomorphological and Functional Sciences, University Federico II of Napoli, Italy
References:
Francis, P.T., Holmes, C., Webster, M.T., Stratmann, G.C., Procter, A.W., Bowen, D.M., Preliminary neurochemical findings in non-Alzheimer dementia due to lobar atrophy (1993) Dementia, 4, pp. 172-17
Procter, A.W., Qurne, M., Francis, P.T., Neurochemical features of frontotemporal dementia (1999) Dement Geriatr Cogn Disord, 10 (SUPPL. 1), pp. 80-84
Litvan, I., Therapy and management of frontal lobe dementia patients (2001) Neurology, 56, pp. S41-S45
Miller, B.L., Ikonte, C., Ponton, M., Levy, M., Boone, K., Darby, A., Berman, N., Cummings, J.L., A study of the Lund-Manchester research criteria for frontotemporal dementia: Clinical and single-photon emission CT correlations (1997) Neurology, 48, pp. 937-942
Mathuranath, P.S., Nestor, P.J., Berrios, G.E., Rakowicz, W., Hodges, J.R., A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia (2000) Neurology, 55, pp. 1613-1620
Siri, S., Benaglio, I., Frigerio, A., Binetti, G., Cappa, S.F., A brief neuropsychological assessment for the differential diagnosis between frontotemporal dementia and Alzheimer's disease (2001) Eur J Neurol, 8, pp. 125-132
Starkstein, S.E., Migliorelli, R., Tesón, A., Sabe, L., Vázquez, S., Turjanski, M., Robinson, R.G., Leiguarda, R., Specificity of changes in cerebral blood flow in patients with frontal lobe dementia (1994) J Neurol Neurosurg Psychiatry, 57, pp. 790-796
Talbot, P.R., Lloyd, J.J., Snowden, J.S., Neary, D., Testa, H.J., A clinical role for 99mTc-HMPAO SPECT in the investigation of dementia? (1998) J Neurol Neurosurg Psychiatry, 64, pp. 306-313
Duara, R., Barker, W., Luis, C.A., Frontotemporal dementia and Alzheimer's disease: Differential diagnosis (1999) Dement Geriatr Cogn Disord, 10 (SUPPL. 1), pp. 37-42
Sjogren, M., Gustafson, L., Wikkelso, C., Wallin, A., Frontotemporal dementia can be distinguished from Alzheimer's disease and subcortical white matter dementia by an anterior-to-posterior rCBF-SPET ratio (2000) Dement Geriatr Cogn Disord, 11, pp. 275-285
Charpentier, P., Lavenu, I., Defebvre, L., Duhamel, A., Lecouffe, P., Pasquier, F., Steinling, M., Alzheimer's disease and frontotemporal dementia are differentiated by discriminant analysis applied to 99mTc HmPAO SPECT data (2000) J Neurol Neurosurg Psychiatry, 69, pp. 661-663
Holman, B.L., Johnson, K.A., Gerada, B., Carvalho, P.A., Satlin, A., The scintigraphic appearance of Alzheimer's disease: A prospective study using technetium-99m-HMPAO SPECT (1992) J Nucl Med, 33, pp. 181-185
Waldemar, G., Bruhn, P., Kristensen, M., Johnsen, A., Paulson, O.B., Lassen, N.A., Heterogeneity of neocortical cerebral blood flow deficits in dementia of the Alzheimer type: A [99mTc]-d,l-HMPAO SPECT study (1994) J Neurol Neurosurg Psychiatry, 57, pp. 285-295
Julin, P., Wahlund, L.O., Basun, H., Persson, A., Mare, K., Rudberg, U., Clinical diagnosis of frontal lobe dementia and Alzheimer's disease: Relation to cerebral perfusion, brain atrophy and electroencephalography (1995) Dementia, 6, pp. 142-147
Ishii, K., Sakamoto, S., Sasaki, M., Kitagaki, H., Yamaji, S., Hashimoto, M., Imamaura, T., Mori, E., Cerebral glucose metabolism in patients with frontotemporal dementia (1998) J Nucl Med, 39, pp. 1875-1878
Acton, P.D., Friston, K.J., Statistical parametric mapping in functional neuroimaging: Beyond PET and fMRI activation studies (1998) Eur J Nucl Med, 25, pp. 663-667
Imran, M.B., Kawashima, R., Awata, S., Sato, K., Kinomura, S., Ono, S., Yoshioka, S., Fukuda, H., Parametric mapping of cerebral blood flow deficits in Alzheimer's disease: A SPECT study using HMPAO and image standardization technique (1999) J Nucl Med, 40, pp. 244-249
Holmes, A., Poline, J.B., Friston, K.J., Characterising brain images with the general linear model (1997) Human brain function, pp. 59-84. , Frackowiak RSJ, ed. San Diego: Academic Press
Garraux, G., Salmon, E., Degueldre, C., Lemaire, C., Laureys, S., Franck, G., Comparison of impaired subcortico-frontal metabolic networks in normal aging, subcortico-frontal dementia, and cortical frontal dementia (1999) Neuroimage, 10, pp. 149-162
Clinical and neuropathological criteria for frontotemporal dementia (1994) J Neurol Neurosurg Psychiatry, 57, pp. 416-418. , The Lund and Manchester groups
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., Stadlan, E.M., Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease (1984) Neurology, 34, pp. 939-944
Chang, L.T., A method for attenuation correction in radionuclide computed tomography (1978) IEEE Trans Nucl Sci, 25, pp. 638-643
Pickut, B.A., Saerens, J., Mariën, P., Borggreve, F., Goeman, J., Vandevivere, J., Vervaet, A., De Deyn, P.P., Discriminative use of SPECT in frontal lobe-type dementia versus (senile) dementia of the Alzheimer's type (1997) J Nucl Med, 38, pp. 929-934
Ishii, K., Sasaki, M., Yamaji, S., Sakamoto, S., Kitagaki, H., Mori, E., Demonstration of decreased posterior cingulate perfusion in mild Alzheimer's disease by means of H2 15O positron emission tomography (1997) Eur J Nucl Med, 24, pp. 670-673
Salmon, E., Van der Linden, M.V., Franck, G., Anterior cingulate and motor network metabolic impairment in progressive supranuclear palsy (1997) Neuroimage, 5, pp. 173-178
Salmon, E., Collette, F., Degueldre, C., Lemaire, C., Franck, G., Voxel-based analysis of confounding effects of age and dementia severity on cerebral metabolism in Alzheimer's disease (2000) Hum Brain Mapping, 10, pp. 39-48
Pagani, M., Salmaso, D., Ramstrom, C., Jonsson, C., Lundqvist, R., Thurfjell, L., Schnell, P.D., Larsson, S.A., Mapping pathological (99m)Tc-d,l-hexamethylpropylene amine oxime uptake in Alzheimer's disease and frontal lobe dementia with SPECT (2001) Dement Geriatr Cogn Disord, 12, pp. 177-184
Mann, D.M., South, P.W., Snowden, J.S., Neary, D., Dementia of frontal lobe type: Neuropathology and immunohistochemistry (1993) J Neurol Neurosurg Psychiatry, 56, pp. 605-614
Sarazin, M., Pillon, B., Giannakopoulos, P., Rancurel, G., Samson, Y., Dubois, B., Clinicometabolic dissociation of cognitive functions and social behavior in frontal lobe lesions (1998) Neurology, 51, pp. 142-148
Devinsky, O., Morrell, M.J., Vogt, B.A., Contributions of anterior cingulate cortex to behaviour (1995) Brain, 118, pp. 279-306
Silberman, E.K., Weingartner, H., Hemispheric lateralization of functions related to emotion (1986) Brain Cogn, 5, pp. 322-353
Kawasaki, H., Kaufman, O., Damasio, H., Damasio, A.R., Granner, M., Bakken, H., Hori, T., Adolphs, R., Single-neuron responses to emotional visual stimuli recorded in human ventral prefrontal cortex (2001) Nat Neurosci, 4, pp. 15-16
Mychack, P., Kramer, J.H., Boone, K.B., Miller, B.L., The influence of right frontotemporal dysfunction on social behavior in frontotemporal dementia (2001) Neurology, 56, pp. S11-S15
Bonte, F.J., Hom, J., Tintner, R., Weiner, M.F., Single photon tomography in Alzheimer's disease and the dementias (1990) Semin Nucl Med, 20, pp. 342-352
O'Brien, J.T., Eagger, S., Syed, G.M., Sahakian, B.J., Levy, R., A study of regional cerebral blood flow and cognitive performance in Alzheimer's disease (1992) J Neurol Neurosurg Psychiatry, 55, pp. 1182-1187
Karbe, H., Kertesz, A., Davis, J., Kemp, B.J., Prato, F.S., Nicholson, R.L., Quantification of functional deficit in Alzheimer's disease using a computer-assisted mapping program for 99mTc-HMPAO SPECT (1994) Neuroradiology, 36, pp. 1-6
Osimani, A., Ichise, M., Chung, D.G., Pogue, J.M., Freedman, M., SPECT for differential diagnosis of dementia and correlation of rCBF with cognitive impairment (1994) Can J Neurol Sci, 21, pp. 104-111
Baron, J.C., Chetelat, G., Desgranges, B., Perchey, G., Landeau, B., De Sayette, V., Eustache, F., In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer's disease (2001) Neuroimage, 14, pp. 298-309
Ebmeier, K.P., Glabus, M.F., Prentice, N., Ryman, A., Goodwin, G.M., A voxel-based analysis of cerebral perfusion in dementia and depression of old age (1998) Neuroimage, 7, pp. 199-208
Bouilleret, V., Dupont, S., Spelle, L., Baulac, M., Samson, Y., Semah, F., Insular cortex involvement in mesiotemporal lobe epilepsy: A positron emission tomography study (2002) Ann Neurol, 51, pp. 202-208
Frisoni, G., Beltramello, A., Geroldi, C., Weiss, C., Bianchetti, A., Trabucchi, M., Brain atrophy in frontotemporal dementia (1996) J Neurol Neurosurg Psychiatry, 61, pp. 157-165
Hodges, J., Frontotemporal dementia (Pick's disease): Clinical features and assessment (2001) Neurology, 56, pp. S6-S10
Signorini, M., Paulesu, E., Friston, K., Perani, D., Colleluori, A., Lucignani, G., Grassi, F., Fazio, F., Rapid assessment of regional cerebral metabolic abnormalities in single subjects with quantitative and nonquantitative [18F]FDG PET: A clinical validation of statistical parametric mapping (1999) Neuroimage, 9, pp. 63-80
Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks
Characteristic patterns of regional cerebral blood flow (rCBF) reduction, as detected by technetium-99m hexamethylpropylene amine oxime 99mTc-HMPAO) single-photon emission tomography (SPET), may help clinicians in differentiating patients with fron-totemporal dementia (FTD) from those with Alzheimer's disease (AD). However, in some cases these patients may share common rCBF abnormalities and the visual analysis and/or the region of interest (ROI) approach may not sensitively detect more localised focal changes that could be more specific for each pathology. Recently, automated voxel-by-voxel statistical analysis of perfusion brain maps has been applied to SPET images. This method has the advantage of including the rCBF information for the whole brain for statistical analysis without any a priori hypothesis regarding the regions possibly involved. This could result in a better characterisation of rCBF differences in brain regions while also reducing the operator's subjectivity and the time required for data analysis. The purpose of this study was to apply such a technique to highlight the specific brain areas showing a relative functional involvement in FTD and AD. Thus, we compared the relative rCBF patterns obtained in eight FTD patients with those obtained in 21 AD patients using 99mTc-HMPAO SPET and statistical parametric mapping (SPM). When FTD patients were compared with AD patients, relatively lower rCBF was observed in right medial frontal cortex (BA 8, 9, 10), right anterior cingulate cortex (BA 32), right temporal cortex (BA 21/22), right orbitofrontal cortex (BA 11) and ventrolateral prefrontal cortex (BA 47); in BA 47 the reduction was evident bilaterally but was more marked on the right side. On the other hand, when AD patients were compared with FTD patients, a significant relative rCBF decrease was found in the bilateral superior parietal cortex (BA 7); this decrease was more extensive on the left side, where it also included the inferior parietal (BA 40), superior occipital (BA 19) and temporo-occipital regions (BA 39, 19). The results of this study confirm the preferential involvement of the frontotemporal regions in FTD patients and of the temporoparietal regions in AD patients. Furthermore, they highlight the networks that are more specifically impaired in these disorders and that could be implicated in the emotional-behavioural and cognitive disturbances that characterise FTD and AD respectively.
Characteristic patterns of regional cerebral blood flow (rCBF) reduction, as detected by technetium-99m hexamethylpropylene amine oxime 99mTc-HMPAO) single-photon emission tomography (SPET), may help clinicians in differentiating patients with fron-totemporal dementia (FTD) from those with Alzheimer's disease (AD). However, in some cases these patients may share common rCBF abnormalities and the visual analysis and/or the region of interest (ROI) approach may not sensitively detect more localised focal changes that could be more specific for each pathology. Recently, automated voxel-by-voxel statistical analysis of perfusion brain maps has been applied to SPET images. This method has the advantage of including the rCBF information for the whole brain for statistical analysis without any a priori hypothesis regarding the regions possibly involved. This could result in a better characterisation of rCBF differences in brain regions while also reducing the operator's subjectivity and the time required for data analysis. The purpose of this study was to apply such a technique to highlight the specific brain areas showing a relative functional involvement in FTD and AD. Thus, we compared the relative rCBF patterns obtained in eight FTD patients with those obtained in 21 AD patients using 99mTc-HMPAO SPET and statistical parametric mapping (SPM). When FTD patients were compared with AD patients, relatively lower rCBF was observed in right medial frontal cortex (BA 8, 9, 10), right anterior cingulate cortex (BA 32), right temporal cortex (BA 21/22), right orbitofrontal cortex (BA 11) and ventrolateral prefrontal cortex (BA 47); in BA 47 the reduction was evident bilaterally but was more marked on the right side. On the other hand, when AD patients were compared with FTD patients, a significant relative rCBF decrease was found in the bilateral superior parietal cortex (BA 7); this decrease was more extensive on the left side, where it also included the inferior parietal (BA 40), superior occipital (BA 19) and temporo-occipital regions (BA 39, 19). The results of this study confirm the preferential involvement of the frontotemporal regions in FTD patients and of the temporoparietal regions in AD patients. Furthermore, they highlight the networks that are more specifically impaired in these disorders and that could be implicated in the emotional-behavioural and cognitive disturbances that characterise FTD and AD respectively.
Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks
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Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks
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Danforth Dn JR, Aloj L, Carrasquillo JA, Bacharach SL, Chow C, Zujewski J, Whatley M, Galen B, Merino M, Neumann RD
* The role of 18F-FDG-PET in the local/regional evaluation of women with breast cancer (275 views)
Breast Cancer Res Tr Kluwer Academic Publishers (ISSN: 0167-6806), 2002; 75(2): 135-146.
Impact Factor: 3.132
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Camera L, Bresciani M, Soscia E, Percopo V, Mainenti PP, Salvatore M
* Morphological imaging of gastroenteropancreatic neuroendocrine tumours (256 views)
Minerva Endocrinol (ISSN: 0391-1977, 1827-1634electronic, 0391-1977linking), 2001 Sep; 26(3): 123-128.
Impact Factor: 1.464
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Cuocolo A, Acampa W
* Nuclear cardiology in the new millennium (324 views)
Rev Esp Med Nucl (ISSN: 0212-6982), 2001 Jun; 20(4): 305-308.
Impact Factor: 0.155
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Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (622 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
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Menna F, Acampa W, Florimonte L, Ferro A, Borrelli G, Mainolfi C, Cuocolo A
99mTc tetrofosmin cardiac tomography after nitrate administration in patients with coronary artery disease and left vetricular dysfunction (333 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2000; 99(4): 258-263.
Impact Factor: 1.368
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Formisano C, Limite G, Lamberti M, Fonti R, Forestieri P
Lymph node mapping and sentinel lymph node biopsy for evaluation of axillary lymph node status in early invasive breast cancer. Our experience (353 views)
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Impact Factor: 0
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Varrone A, Soricelli A, Postiglione A, Salvatore M
Comparison between cortical distribution of I-123 lomazenil and Tc-99m HMPAO in patients with Alzheimer's disease using SPECT (312 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Sep; 24(9): 660-665.
Impact Factor: 0.253
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Nicolai E, Cuocolo A, Acampa W, Varrone A, Pace L, Salvatore M
Exercise-test Tc-99m tetrofosmin SPECT in patients with chronic ischemic left ventricular dysfunction: direct comparison with Ti-201 reinjection (302 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1999 May; 6(3): 270-277.
Impact Factor: 1.765
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Gisonni P, Cuocolo A, Spinelli L, Acampa W, Florimonte L, Nicolai E, Petretta M, Sodano A
99mTc sestamibi cardiac tomography and dobutamine echocardiography in the identification of reversible left ventricular dysfunction in patients with acute myocardial infarction (284 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1999 Apr; 97(4): 265-270.
Impact Factor: 0.967
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Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (387 views)
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Impact Factor: 0.957
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (373 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Ferone D, Lastoria S, Colao A, Varrella P, Cerbone G, Acampa W, Merola B, Salvatore M, Lombardi G
Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas (317 views)
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Impact Factor: 5.641
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Mainolfi C, Maurea S, Varrella P, Alaia C, Imparato C, Alfano B, Abate G, Bazzicalupo L
18-FDG PET in the staging and follow-up of lymphoma patients: Comparison with clinical and radiologic findings (323 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 1998; 95(1-2): 98-104.
Impact Factor: 0.967
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Postiglione A, Soricelli A, Grossi D, Romano M, Mainenti PP, Ruocco A, Fragrassi N, Chiacchio L, Milan G, De Chiara S, Brunetti A
Changes in cerebral blood flow during cognitive activation evaluated by single photon emission computed tomography in patients with Alzheimer's disease (449 views)
Alzheimer S Res (ISSN: 1356-918x), 1997 Jun; 3(3): 93-99.
Impact Factor: 0
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Postiglione A, Soricelli, Salvatore M, Lassen NA
123I-iomazenil as a clinical tool for studying neuronal loss [4] (340 views)
J Am Geriatr Soc (ISSN: 0002-8614), 1997 Apr; 45(4): 534-536.
Impact Factor: 2.806
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Brunetti A, Alfano B, Soricelli A, Tedeschi E, Mainolfi C, Covelli EM, Aloj L, Panico M, Bazzicalupo L, Salvatore M
Functional characterization of brain tumors: An overview of the potential clinical value (747 views) (PDF 245 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 699-715.
Impact Factor: 1.042
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Soricelli A, Mainenti PP, Leone D, Discepolo A, Romano M, Varrone A, Servillo G, Serio S, Brunetti A, Salvatore M
Evaluation of brain perfusion with high resolution single photon emission tomography in the diagnosis of brain death (238 views)
Minerva Anestesiol (ISSN: 0375-9393), 1996 Jun; 62(6): 209-212.
Impact Factor: 1.627
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Postiglione A, Soricelli A, Covelli EM, Iazzetta N, Ruocco A, Milan G, Santoro L, Alfano B, Brunetti A
Premature aging in Werner's syndrome spares the central nervous system (600 views) (PDF 210 views)
Neurobiol Aging (ISSN: 0197-4580, 1558-1497electronic, 0197-4580linking), 1996 May; 17(3): 325-330.
Impact Factor: 2.872
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Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (451 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (336 views)
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Impact Factor: 2.125
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Soricelli A, Postiglione A, Cuocolo A, De Chiara S, Ruocco A, Brunetti A, Salvatore M, Ell PJ
EFFECT OF ADENOSINE ON CEREBRAL BLOOD-FLOW AS EVALUATED BY SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY IN NORMAL SUBJECTS AND IN PATIENTS WITH OCCLUSIVE CAROTID DISEASE - A COMPARISON WITH ACETAZOLAMIDE (256 views)
Stroke (ISSN: 0039-2499), 1995 Sep; 26(9): 1572-1576.
Impact Factor: 4.323
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Klain M, Imbriaco M, Cuocolo A, Celentano L, Maurea S, Carrillo F, Salvatore M
Morphofunctional evaluation of the kidney in retroperitoneal fibrosis. Correlations of computerized tomography, magnetic resonance and radionuclide renography (264 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994 Jul; 88(1-2): 146-149.
Impact Factor: 0.967
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Brunetti A, Mangoni di S Stefano ML, Chirianni A, Bonadies G, Celentano L, Foggia M, Tedeschi E, Cataldo PT, Piazza M, Salvatore M
Scintigraphy with gallium-67 citrate in patients with AIDS: pathologic extrapulmonary uptake (219 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994 May; 87(5): 683-687.
Impact Factor: 0.967
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Maurea S, Cuocolo A, Reynolds J, Keiser H, Neumann R, Salvatore M
Iodine-131 metaiodobenzylguanidine scintigraphy in the evaluation of paragangliomas. Comparison between benign and malignant tumors (252 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 87(5): 688-693.
Impact Factor: 0.967
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Brunetti A, Tedeschi E, Belfiore G, Salvatore M
Neuroblastoma metastasis to the falx cerebri. A case report (287 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992 Apr; 83(4): 467-470.
Impact Factor: 0.967
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Nappi A, Cuocolo A, Nicolai E, Imbriaco M, Pace L, Salvatore M
Ambulatory monitoring of left ventricular function with a radionuclide detector system (295 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 84(1-2): 132-139.
Impact Factor: 0.967
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Cuocolo A, Nappi A, Nicolai E, Pace L, Imbriaco M, Morisco C, Chiariello M, Trimarco B, Salvatore M
Ambulatory monitoring of left ventricular function: the assessment of transient episodes of ventricular dysfunction in patients with ischemic cardiopathy (347 views)
G Ital Cardiol (ISSN: 0046-5968), 1992; 22(7): 813-824.
Impact Factor: 0
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Maurea S, Maurelli L, Lastoria S, Cuocolo A, Brunetti A, Pace L, Caracò C, Klain M, Lupoli G, Salvatore M
Familial pheochromocytoma in Sipple's syndrome. A comparison between scintigraphy with 131I-meta-iodobenzylguanidine, computed tomography and echography (251 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 83(4): 486-490.
Impact Factor: 0.967
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Pace L, Cuocolo A, Nappi A, Nicolai E, Imbriaco M, Mangoni di Santo Stefano ML, Salvatore M
Myocardial scintigraphy with technetium 99m methoxyisobutylisonitrile. A comparison with coronary arteriography in patients with suspected ischemic cardiopathy (503 views)
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Impact Factor: 0.967
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Maurelli L, Cuocolo A, Lastoria S, Brunetti A, Maurea S, Lembo G, Klain M, Carac C, Salvatore M
131I-meta-iodobenzylguanidine scintigraphy in patients with a suspected pheochromocytoma. A comparison with CT and biohumoral parameters (442 views)
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Impact Factor: 0.967
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Salvatore M, López-Majano V, Pace L, Alfano B
The use of single-photon emission computed tomography in cardiology (554 views)
Kardiologiia (ISSN: 0022-9040), 1988 Sep; 28(8): 34-36.
Impact Factor: 0.216
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Marchetti P, Benzi L, Trischitta V, Brunetti A, Cecchetti P, Ciccarone AM, Pezzino V, Vigneri R, Navalesi R
Complementary use of gel permeation and reversed-phase liquid chromatography for the analysis of A14-[125I]insulin and its degradation products in isolated human monocytes (1719 views)
J Chromatogr B Biomed Sci Appl (ISSN: 0378-4347), 1986 Apr 25; 377(C): 339-344.
Impact Factor: 1.588
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* CD33 and SIGLECL1 Immunoglobulin Superfamily Involved in Dementia (94 views)
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Impact Factor: 3.51
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Milan G, Napoletano S, Pappata S, Gentile MT, Colucci-d'Amato L, Della Rocca G, Maciag A, Rossetti CP, Fucci L, Puca A, Grossi D, Postiglione A, Vitale E
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Impact Factor: 4.454
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Perani D, Della Rosa PA, Cerami C, Gallivanone F, Fallanca F, Vanoli EG, Panzacchi A, Nobili F, Pappata S, Marcone A, Garibotto V, Castiglioni I, Magnani G, Cappa SF, Gianolli L; EADC-PET Consortium
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Impact Factor: 2.526
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De Rosa A, Pappata S, Pellegrino T, De Leva MF, Maddaluno G, Fiumara G, Carotenuto R, Petretta M, Filla A, De Michele G, Cuocolo A
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Impact Factor: 2.692
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Iodice D, Di Donato O, Liccardo I, Lamanna L, Segreto S, Salvatore M, Imbriaco M
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Impact Factor: 1.368
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Maffei E, Midiri M, Russo V, Rengo M, Tedeschi C, Spagnolo P, Seitun S, Francone M, Guaricci AI, Carrabba N, Malagò R, Cuocolo A, Arcadi T, Catalano OA, Cademartiri F
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Impact Factor: 1.368
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Storto G, Gallicchio R, Pellegrino T, Nardelli A, Capacchione D, Sirignano C, Pace L
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Impact Factor: 2.408
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Mancini M, Di Donato O, Saldalamacchia G, Liuzzi R, Rivellese A, Salvatore M
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Impact Factor: 1.368
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Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
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Impact Factor: 5.774
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Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
* 3'-deoxy-3'-18F-fluorothymidine PET/CT to guide therapy with epidermal growth factor receptor antagonists and Bcl-xL inhibitors in non-small cell lung cancer (525 views)
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Impact Factor: 5.774
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Petretta M, Acampa W, Zampella E, Assante R, Petretta MP, Cuocolo R, Fabiani I, Della Rattal GL, Perrone-Filardi P, Cuocolo A
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Impact Factor: 7.132
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Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
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Impact Factor: 8.312
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Varrone A, Halldin C
Molecular imaging of the dopamine transporter (542 views)
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Impact Factor: 7.022
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
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Impact Factor: 5.036
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Pappata S, Varrone A, Vicidomini C, Milan G, De Falco C, Sansone V, Iavarone A, Comerci M, Loré E, Panico M, Quarantelli M, Postiglione A, Salvatore M
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Impact Factor: 5.036
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Lanzillo R, Orefice G, Quarantelli M, Rinaldi C, Prinster A, Ventrella G, Spitaleri D, Lus G, Vacca G, Carotenuto B, Salvatore E, Brunetti A, Tedeschi G, Brescia Morra V
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Impact Factor: 4.23
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Caprio MG, Cangiano A, Imbriaco M, Soscia F, Di Martino G, Farina A, Avitabile G, Pace L, Forestieri P, Salvatore M
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Impact Factor: 1.618
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Monfregola L, Saviano M, De Luca S
* Synthesis and Characterization of a Selective Alpha(v)Beta(3) Receptor Cyclic Peptide Antagonist Functionalized with a Chelating Group for Metal Labelling (378 views)
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Impact Factor: 1.034
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Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
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Impact Factor: 6.069
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Kapucu OL, Nobili F, Varrone A, Booij J, Vander Borght T, Nagren K, Darcourt J, Tatsch K, Van Laere KJ
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Impact Factor: 4.531
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Varrone A, Asenbaum S, Vander Borght T, Booij J, Nobili F, Någren K, Darcourt J, Kapucu OL, Tatsch K, Bartenstein P, Van Laere K
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Impact Factor: 4.531
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Takano A, Gulyas B, Varrone A, Maguire RP, Halldin C
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Impact Factor: 4.531
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Storto G, Nicolai E, Salvatore M
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Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009 Apr; 53(2): 167-180.
Impact Factor: 1.724
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Evangelista L, Acampa W, Petretta M, Ferro A, Ricci F, Luongo L, Daniele S, Punzo G, Cuocolo A
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Impact Factor: 2.777
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Zannetti A, Iommelli F, Fonti R, Papaccioli A, Sommella J, Lettieri A, Pirozzi G, Bianco R, Tortora G, Salvatore M, Del Vecchio S
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Impact Factor: 6.488
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Accardo A, Tesauro D, Aloj L, Tarallo L, Arra C, Mangiapia G, Vaccaro M, Pedone C, Paduano L, Morelli G
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Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2008 Apr; 3(4): 594-602.
Impact Factor: 3.15
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Pulcrano M, Camera L, Pagano L, Del Vecchio S, Ferone D, Bodei L, Murgia A, Pace L, Storto G, Paganelli G, Colao A, Salvatore M, Lombardi G, Biondi B
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Impact Factor: 1.888
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Saviano M, De Luca S, Morelli G, Tesauro D, Pedone C
* Preparation and use of cyclic and branched peptides and their labelled derivatives as therapeutic agents, cholecystokinin agonists or antagonists, and diagnostic agents to identify and locate tumours (432 views)
Patents Official Gazette Of The United States Patent And Trademark Office (ISSN: 0098-1133), 2008 Feb 12; N/D: N/D-N/D.
Impact Factor: 0
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
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Impact Factor: 6.662
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Milan G, Lamenza F, Iavarone A, Galeone F, Lore E, De Falco C, Sorrentino P, Postiglione A
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Impact Factor: 2.317
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Postiglione A, Milan G, Pappata S, De Falco C, Lamenza F, Schiattarella V, Gallotta G, Sorrentino P, Striano S
* Fronto-temporal dementia presenting as Geschwind's syndrome (475 views)
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Impact Factor: 0.918
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Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (476 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
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Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (478 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
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De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
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Cuocolo A, Acampa W, Varrone A, Salvatore M
* Highlights of the Annual Congress of the European Association of Nuclear Medicine, Istanbul, 2005: The incremental value of nuclear medicine for patient management and care (584 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Mar; 33(3): 360-381.
Impact Factor: 4.041
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Pace L, Salvatore M, Del Vecchio S
* Use of Tc-99m-Sestamibi scintigraphy in multiple myeloma (241 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2006 Mar; 47(3): 555-555.
Impact Factor: 4.986
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Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Salvatore B, Andretta C, Di Nuzzo C, Rotoli B, Salvatore M
* Washout of [99mTc] sestamibi in predicting response to chemotherapy in patients with multiple myeloma (381 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Sep; 49(3): 281-285.
Impact Factor: 1.724
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Rispo A, Imbriaco M, Celentano L, Cozzolino A, Camera L, Mainenti PP, Manguso F, Sabbatini F, D'Amico P, Castiglione F
* Noninvasive diagnosis of small bowel Crohn's disease: Combined use of bowel sonography and Tc-99m-HMPAO leukocyte scintigraphy (420 views)
Inflamm Bowel Dis (ISSN: 1078-0998, 1536-4844electronic), 2005 Apr; 11(4): 376-382.
Impact Factor: 3.012
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Acampa W, Spinelli L, Petretta M, De Lauro F, Ibello F, Cuocolo A
* Prognostic value of myocardial ischemia in patients with uncomplicated acute myocardial infarction: Direct comparison of stress echocardiography and myocardial perfusion imaging (290 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Mar; 46(3): 417-423.
Impact Factor: 4.684
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Pace L, Del Vecchio S, Salvatore M
* Technetium 99m sestamibi in multiple myeloma (273 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005 Jan; 234(1): 312-313.
Impact Factor: 5.377
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Pace L, Del Vecchio S, Salvatore M, Walker RC, Angtuaco E, Sethi R, Fassas A, Barlogie B
* Technetium 99m sestamibi in multiple myeloma [3] (multiple letters) (339 views)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005; 234(1): 312-313.
Impact Factor: 5.377
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Rispo A, Imbriaco M, Celentano L, Cozzolino A, Mainenti PP, Camera L, Di Girolamo E, De Falco T, Castiglione F
* Small bowel Crohn's disease: Comparison of enteroclysis, bowel sonography and Tc-99m-HMPAO leukocyte scintigraphy (340 views)
Eur Rev Med Pharmacol Sci (ISSN: 1128-3602), 2004 Sep; 8(5): 219-224.
Impact Factor: 0.988
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Del Vecchio S, Salvatore M
* Tc-99m-MIBI in the evaluation of breast cancer biology (600 views) (PDF 182 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Jun; 31(SUPPL.1): S88-S88.
Impact Factor: 3.935
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Aloj L, Caracò C, Panico M, Zannetti A, Del Vecchio S, Tesauro D, De Luca S, Arra C, Pedone C, Morelli G, Salvatore M
* In vitro and in vivo evaluation of In-111-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (587 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2004 Mar; 45(3): 485-494.
Impact Factor: 5.362
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Quarantelli M, Berkouk K, Prinster A, Landeau B, Svarer C, Balkay L, Alfano B, Brunetti A, Baron JC, Salvatore M
* Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction (555 views) (PDF 259 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2004 Feb; 45(2): 192-201.
Impact Factor: 5.362
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Pace L, Salvatore M, Del Vecchio S
* A new role for nuclear medicine in multiple Myeloma (322 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Sep; 44(8): 1369-1369.
Impact Factor: 4.899
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Spinelli L, Petretta M, Acampa W, He W, Petretta A, Bonaduce D, Cuocolo A
* Prognostic value of combined assessment of regional left ventricular function and myocardial perfusion by dobutamine and rest gated SPECT in patients with uncomplicated acute myocardial infarction (429 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Jul; 44(7): 1023-1029.
Impact Factor: 4.899
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (527 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Kim KM, Varrone A, Watabe H, Shidahara M, Fujita M, Innis RB, Iida H
* Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities (278 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Apr; 44(4): 512-519.
Impact Factor: 4.899
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Camera L, Del Vecchio S, Quarantelli M, Ibello F, Pellegrino T, Salvatore M
* Radiolabeled somatostatin analogs in the diagnosis and staging of neuroendocrine tumors (329 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2003; 26(8Suppl): 60-62.
Impact Factor: 1.621
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Pappata S, Dehaene S, Poline JB, Gregoire MC, Jobert A, Delforge J, Frouin V, Bottlaender M, Dolle F, Di Giamberardino L, Syrota A
* In Vivo detection of striatal dopamine release during reward: A PET study with [11C]raclopride and a single dynamic scan approach (377 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 16(4): 1015-1027.
Impact Factor: 5.624
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Caracò C, Fonti R, Botti G, D'Aiuto G, Salvatore M
* Dynamic coupling of Tc-99m-MIBI efflux and apoptotic pathway activation in untreated breast cancer patients (483 views)
Eur J Nucl Med (ISSN: 1619-7070, 0340-6997, 1619-7089), 2002 Jun; 29(6): 809-814.
Impact Factor: 3.568
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Fonti R, Limite G, Sodano A, Riccardi A, Forestieri P, De Cristofaro G, Pettinato G, Salvatore M
* Sentinel lymph node identification in breast cancer patients (314 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2002 Apr; 103(4): 370-377.
Impact Factor: 1.368
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Danforth Dn JR, Aloj L, Carrasquillo JA, Bacharach SL, Chow C, Zujewski J, Whatley M, Galen B, Merino M, Neumann RD
* The role of 18F-FDG-PET in the local/regional evaluation of women with breast cancer (275 views)
Breast Cancer Res Tr Kluwer Academic Publishers (ISSN: 0167-6806), 2002; 75(2): 135-146.
Impact Factor: 3.132
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Camera L, Bresciani M, Soscia E, Percopo V, Mainenti PP, Salvatore M
* Morphological imaging of gastroenteropancreatic neuroendocrine tumours (256 views)
Minerva Endocrinol (ISSN: 0391-1977, 1827-1634electronic, 0391-1977linking), 2001 Sep; 26(3): 123-128.
Impact Factor: 1.464
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Cuocolo A, Acampa W
* Nuclear cardiology in the new millennium (324 views)
Rev Esp Med Nucl (ISSN: 0212-6982), 2001 Jun; 20(4): 305-308.
Impact Factor: 0.155
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Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (622 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
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Menna F, Acampa W, Florimonte L, Ferro A, Borrelli G, Mainolfi C, Cuocolo A
99mTc tetrofosmin cardiac tomography after nitrate administration in patients with coronary artery disease and left vetricular dysfunction (333 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2000; 99(4): 258-263.
Impact Factor: 1.368
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Formisano C, Limite G, Lamberti M, Fonti R, Forestieri P
Lymph node mapping and sentinel lymph node biopsy for evaluation of axillary lymph node status in early invasive breast cancer. Our experience (353 views)
Przegl Lek (ISSN: 0033-2240print, 0033-2240linking), 2000; 57Suppl5: 113-115.
Impact Factor: 0
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Varrone A, Soricelli A, Postiglione A, Salvatore M
Comparison between cortical distribution of I-123 lomazenil and Tc-99m HMPAO in patients with Alzheimer's disease using SPECT (312 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Sep; 24(9): 660-665.
Impact Factor: 0.253
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Nicolai E, Cuocolo A, Acampa W, Varrone A, Pace L, Salvatore M
Exercise-test Tc-99m tetrofosmin SPECT in patients with chronic ischemic left ventricular dysfunction: direct comparison with Ti-201 reinjection (302 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1999 May; 6(3): 270-277.
Impact Factor: 1.765
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Gisonni P, Cuocolo A, Spinelli L, Acampa W, Florimonte L, Nicolai E, Petretta M, Sodano A
99mTc sestamibi cardiac tomography and dobutamine echocardiography in the identification of reversible left ventricular dysfunction in patients with acute myocardial infarction (284 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1999 Apr; 97(4): 265-270.
Impact Factor: 0.967
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Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (387 views)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (373 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Ferone D, Lastoria S, Colao A, Varrella P, Cerbone G, Acampa W, Merola B, Salvatore M, Lombardi G
Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas (317 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1998 Jan; 83(1): 248-252.
Impact Factor: 5.641
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Mainolfi C, Maurea S, Varrella P, Alaia C, Imparato C, Alfano B, Abate G, Bazzicalupo L
18-FDG PET in the staging and follow-up of lymphoma patients: Comparison with clinical and radiologic findings (323 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 1998; 95(1-2): 98-104.
Impact Factor: 0.967
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Postiglione A, Soricelli A, Grossi D, Romano M, Mainenti PP, Ruocco A, Fragrassi N, Chiacchio L, Milan G, De Chiara S, Brunetti A
Changes in cerebral blood flow during cognitive activation evaluated by single photon emission computed tomography in patients with Alzheimer's disease (449 views)
Alzheimer S Res (ISSN: 1356-918x), 1997 Jun; 3(3): 93-99.
Impact Factor: 0
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Postiglione A, Soricelli, Salvatore M, Lassen NA
123I-iomazenil as a clinical tool for studying neuronal loss [4] (340 views)
J Am Geriatr Soc (ISSN: 0002-8614), 1997 Apr; 45(4): 534-536.
Impact Factor: 2.806
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Brunetti A, Alfano B, Soricelli A, Tedeschi E, Mainolfi C, Covelli EM, Aloj L, Panico M, Bazzicalupo L, Salvatore M
Functional characterization of brain tumors: An overview of the potential clinical value (747 views) (PDF 245 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 699-715.
Impact Factor: 1.042
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Soricelli A, Mainenti PP, Leone D, Discepolo A, Romano M, Varrone A, Servillo G, Serio S, Brunetti A, Salvatore M
Evaluation of brain perfusion with high resolution single photon emission tomography in the diagnosis of brain death (238 views)
Minerva Anestesiol (ISSN: 0375-9393), 1996 Jun; 62(6): 209-212.
Impact Factor: 1.627
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Postiglione A, Soricelli A, Covelli EM, Iazzetta N, Ruocco A, Milan G, Santoro L, Alfano B, Brunetti A
Premature aging in Werner's syndrome spares the central nervous system (600 views) (PDF 210 views)
Neurobiol Aging (ISSN: 0197-4580, 1558-1497electronic, 0197-4580linking), 1996 May; 17(3): 325-330.
Impact Factor: 2.872
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Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (451 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (336 views)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
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Soricelli A, Postiglione A, Cuocolo A, De Chiara S, Ruocco A, Brunetti A, Salvatore M, Ell PJ
EFFECT OF ADENOSINE ON CEREBRAL BLOOD-FLOW AS EVALUATED BY SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY IN NORMAL SUBJECTS AND IN PATIENTS WITH OCCLUSIVE CAROTID DISEASE - A COMPARISON WITH ACETAZOLAMIDE (256 views)
Stroke (ISSN: 0039-2499), 1995 Sep; 26(9): 1572-1576.
Impact Factor: 4.323
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Klain M, Imbriaco M, Cuocolo A, Celentano L, Maurea S, Carrillo F, Salvatore M
Morphofunctional evaluation of the kidney in retroperitoneal fibrosis. Correlations of computerized tomography, magnetic resonance and radionuclide renography (264 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994 Jul; 88(1-2): 146-149.
Impact Factor: 0.967
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Brunetti A, Mangoni di S Stefano ML, Chirianni A, Bonadies G, Celentano L, Foggia M, Tedeschi E, Cataldo PT, Piazza M, Salvatore M
Scintigraphy with gallium-67 citrate in patients with AIDS: pathologic extrapulmonary uptake (219 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994 May; 87(5): 683-687.
Impact Factor: 0.967
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Maurea S, Cuocolo A, Reynolds J, Keiser H, Neumann R, Salvatore M
Iodine-131 metaiodobenzylguanidine scintigraphy in the evaluation of paragangliomas. Comparison between benign and malignant tumors (252 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 87(5): 688-693.
Impact Factor: 0.967
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Brunetti A, Tedeschi E, Belfiore G, Salvatore M
Neuroblastoma metastasis to the falx cerebri. A case report (287 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992 Apr; 83(4): 467-470.
Impact Factor: 0.967
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Nappi A, Cuocolo A, Nicolai E, Imbriaco M, Pace L, Salvatore M
Ambulatory monitoring of left ventricular function with a radionuclide detector system (295 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 84(1-2): 132-139.
Impact Factor: 0.967
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Cuocolo A, Nappi A, Nicolai E, Pace L, Imbriaco M, Morisco C, Chiariello M, Trimarco B, Salvatore M
Ambulatory monitoring of left ventricular function: the assessment of transient episodes of ventricular dysfunction in patients with ischemic cardiopathy (347 views)
G Ital Cardiol (ISSN: 0046-5968), 1992; 22(7): 813-824.
Impact Factor: 0
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Maurea S, Maurelli L, Lastoria S, Cuocolo A, Brunetti A, Pace L, Caracò C, Klain M, Lupoli G, Salvatore M
Familial pheochromocytoma in Sipple's syndrome. A comparison between scintigraphy with 131I-meta-iodobenzylguanidine, computed tomography and echography (251 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 83(4): 486-490.
Impact Factor: 0.967
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Pace L, Cuocolo A, Nappi A, Nicolai E, Imbriaco M, Mangoni di Santo Stefano ML, Salvatore M
Myocardial scintigraphy with technetium 99m methoxyisobutylisonitrile. A comparison with coronary arteriography in patients with suspected ischemic cardiopathy (503 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 1992; 83(1-2): 97-100.
Impact Factor: 0.967
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Maurelli L, Cuocolo A, Lastoria S, Brunetti A, Maurea S, Lembo G, Klain M, Carac C, Salvatore M
131I-meta-iodobenzylguanidine scintigraphy in patients with a suspected pheochromocytoma. A comparison with CT and biohumoral parameters (442 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1991; 82(6): 839-843.
Impact Factor: 0.967
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Salvatore M, López-Majano V, Pace L, Alfano B
The use of single-photon emission computed tomography in cardiology (554 views)
Kardiologiia (ISSN: 0022-9040), 1988 Sep; 28(8): 34-36.
Impact Factor: 0.216
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Marchetti P, Benzi L, Trischitta V, Brunetti A, Cecchetti P, Ciccarone AM, Pezzino V, Vigneri R, Navalesi R
Complementary use of gel permeation and reversed-phase liquid chromatography for the analysis of A14-[125I]insulin and its degradation products in isolated human monocytes (1719 views)
J Chromatogr B Biomed Sci Appl (ISSN: 0378-4347), 1986 Apr 25; 377(C): 339-344.
Impact Factor: 1.588
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85 Records (80 excluding Abstracts).
Total impact factor: 251.28 (230.554 excluding Abstracts).
Total 5 year impact factor: 287.605 (263.306 excluding Abstracts).
Total impact factor: 251.28 (230.554 excluding Abstracts).
Total 5 year impact factor: 287.605 (263.306 excluding Abstracts).
443 views. Last view on Thursday 23 February 2023, 18:28:40
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