Gastrin and cholecystokinin peptide-based radiopharmaceuticals: An in vivo and in vitro comparison(380 views) Tornesello AL, Aurilio M, Accardo A, Tarallo L, Barbieri A, Arra C, Tesauro D, Morelli G, Aloj L
Keywords: Ga And In Complexes, Minigastrin And Cck8 Peptide Conjugates, Nuclear Medicine, Cholecystokinin B Receptor, Cholecystokinin Octapeptide Derivative, Gallium 68, Gastrin Derivative, Indium 111, Animal Experiment, Article, Comparative Study, Controlled Study, Drug Structure, Drug Transport, Drug Uptake, In Vitro Study, In Vivo Study, Internalization, Isotope Labeling, Mouse, Nonhuman, Priority Journal, Cell Line, Tumor, Gallium Radioisotopes, Indium Radioisotopes,
Affiliations: *** IBB - CNR ***
Department of Biological Sciences, CIRPeB, University of Naples Federico II, IBB CNR, Via Mezzocannone 16, 80134 Naples, Italy
Department of Nuclear Medicine, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, Via M. Semmola, 80131 Naples, Italy
Animal Experimentation Facility, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, Via M. Semmola, 80131 Naples, Italy
INBIOS srl, Via Pietro Castellino 131, 80131 Naples, Italy
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Behr, T. M., Gotthardt, M., Barth, A., Behe, M., Imaging tumors with peptide-based radioligands (2001) Q. J. Nucl. Med., 45, pp. 189-20
Reubi, J. C., Peptide receptors as molecular targets for cancer diagnosis and therapy (2003) Endocr. Rev., 24, pp. 389-427
Kwekkeboom, D. J., Mueller-Brand, J., Paganelli, G., Anthony, L. B., Pauwels, S., Kvols, L. K., O'Dorisio, T. M., Krenning, E. P., Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs (2005) J. Nucl. Med., 46 (SUPPL. 1), pp. 62S-66S
Wank, S. A., G protein-coupled receptors in gastrointestinal physiology. I. CCK receptors: an exemplary family (1998) Am. J. Physiol., 274, pp. G607-G613
Reubi, J. C., Schaer, J. C., Waser, B., Cholecystokinin CCK) -A and CCK-B/gastrin receptors in human tumors (1997) Cancer Res., 57, pp. 1377-1386
Behr, T. M., Behe, M. P., Cholecystokinin-B/Gastrin receptor-targeting peptides for staging and therapy of medullary thyroid cancer and other cholecystokinin-B receptor-expressing malignancies (2002) Semin. Nucl. Med., 32, pp. 97-109
Reubi, J. C., Waser, B., Schaer, J. C., Laederach, U., Erion, J., Srinivasan, A., Schmidt, M. A., Bugaj, J. E., Unsulfated DTPA- and DOTA-CCK analogs as specific high-affinity ligands for CCK-B receptor-expressing human and rat tissues in vitro and in vivo (1998) Eur. J. Nucl. Med., 25, pp. 481-490
Nock, B. A., Maina, T., Behe, M., Nikolopoulou, A., Gotthardt, M., Schmitt, J. S., Behr, T. M., Macke, H. R., CCK-2/gastrin receptor-targeted tumor imaging with 99m) Tc-labeled minigastrin analogs (2005) J. Nucl. Med., 46, pp. 1727-1736
Froberg, A. C., de Jong, M., Nock, B. A., Breeman, W. A., Erion, J. L., Maina, T., Verdijsseldonck, M., Krenning, E. P., Comparison of three radiolabelled peptide analogues for CCK-2 receptor scintigraphy in medullary thyroid carcinoma (2009) Eur. J. Nucl. Med. Mol. Imaging, 36, pp. 1265-1272
Behr, T. M., Jenner, N., Behe, M., Angerstein, C., Gratz, S., Raue, F., Becker, W., Radiolabeled peptides for targeting cholecystokinin-B/gastrin receptor-expressing tumors (1999) J. Nucl. Med., 40, pp. 1029-1044
Anelli, P. L., Fedeli, F., Gazzotti, O., Lattuada, L., Lux, G., Rebasti, F., L-Glutamic acid and L-lysine as useful building blocks for the preparation of bifunctional DTPA-like ligands (1999) Bioconjugate Chem., 10, pp. 137-140
Zhernosekov, K. P., Filosofov, D. V., Baum, R. P., Aschoff, P., Bihl, H., Razbash, A. A., Jahn, M., Rosch, F., Processing of generator-produced 68Ga for medical application (2007) J. Nucl. Med., 48, pp. 1741-1748
Mather, S. J., McKenzie, A. J., Sosabowski, J. K., Morris, T. M., Ellison, D., Watson, S. A., Selection of radiolabeled gastrin analogs for peptide receptor-targeted radionuclide therapy (2007) J. Nucl. Med., 48, pp. 615-622
Gastrin and cholecystokinin peptide-based radiopharmaceuticals: An in vivo and in vitro comparison
Aloj L, Aurilio M, Rinaldi V, D'Ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R, Von Guggenberg E, Joosten L, Sosabowski JK, Breeman WA, De Blois E, Koelewijn S, Melis M, Waser B, Beetschen K, Reubi JC, De Jong M * The EEE project(449 views) Proc Int Cosm Ray Conf Icrc Universidad Nacional Autonoma De Mexico, 2007; 5(HEPART2): 977-980. Impact Factor:0 ViewExport to BibTeXExport to EndNote