Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia (722 views) (PDF public 234 views)
Prog Neuropsychopharmacol Biol Psychiatry (ISSN: 0278-5846, 0278-5846linking), 2012 Jun 1; 37(2): 264-269.
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Paper type: Journal Article
Impact factor: 3.552, 5-year impact factor: 3.505
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84859586739&partnerID=40&md5=9c1984954523b894b9793857413d9802
Keywords: Deficit Schizophrenia, Dorsolateral Prefrontal Cortex, Mri, Negative Symptoms, Adult, Article, Brain Region, Brain Size, Clinical Assessment, Controlled Study, Female, Gray Matter, Hippocampus, Human, Major Clinical Study, Morphometrics, Neuroimaging, Neuropathology, Nuclear Magnetic Resonance Imaging, Social Interaction, Adolescent, Three-Dimensional, Middle Aged, Organ Size, Psychiatric Status Rating Scales, Prefrontal Cortex Pathology , Schizophrenia Diagnosis Pathology
Affiliations:
*** IBB - CNR ***
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Biostructure and Bioimaging Institute, CNR and Diagnostic Imaging, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy
References:
Not available.
Prog Neuropsychopharmacol Biol Psychiatry (ISSN: 0278-5846, 0278-5846linking), 2012 Jun 1; 37(2): 264-269.
Export to BibTeX Export to EndNote
Paper type: Journal Article
Impact factor: 3.552, 5-year impact factor: 3.505
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84859586739&partnerID=40&md5=9c1984954523b894b9793857413d9802
Keywords: Deficit Schizophrenia, Dorsolateral Prefrontal Cortex, Mri, Negative Symptoms, Adult, Article, Brain Region, Brain Size, Clinical Assessment, Controlled Study, Female, Gray Matter, Hippocampus, Human, Major Clinical Study, Morphometrics, Neuroimaging, Neuropathology, Nuclear Magnetic Resonance Imaging, Social Interaction, Adolescent, Three-Dimensional, Middle Aged, Organ Size, Psychiatric Status Rating Scales, Prefrontal Cortex Pathology , Schizophrenia Diagnosis Pathology
Affiliations:
*** IBB - CNR ***
Department of Psychiatry, University of Naples SUN, Largo Madonna delle Grazie, 80138 Naples, Italy
Biostructure and Bioimaging Institute, CNR and Diagnostic Imaging, University of Naples Federico II, Via Pansini, 5, 80131 Naples, Italy
References:
Not available.
Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia
Deficit schizophrenia (DS) represents a promising putative clinical subtype of schizophrenia and is characterized by the presence of primary and enduring negative symptoms. Previous studies have often reported a reduced amount of gray matter within prefrontal and temporal cortices in schizophrenia subjects with prevailing negative symptoms; however, the evidence concerning brain structural abnormalities in patients with DS remains controversial.The aim of the present study was to investigate whether patients with DS differed from those with nondeficit schizophrenia (NDS) with respect to the volume of the dorsolateral prefrontal cortex (DLPFC) and hippocampus, two brain areas considered as key regions in the pathogenesis of schizophrenia.In the present study a 3D-T1w MR imaging procedure and an extensive clinical assessment was carried out in 18 patients with schizophrenia, (10 DS and 8 NDS). 3D MPRAGE images were preprocessed with SPM software and two regions of interest (hippocampus and DLPFC) were manually traced to obtain their gray matter volumes.We found a significant reduction of DLPFC in the entire schizophrenia group, with respect to healthy subjects. Although the subgroup of patients with DS had a more severe clinical picture and more impaired social functioning, the DLPFC volume reduction was greater in NDS than in DS patients.In conclusion, according to our structural neuroimaging findings, DS patients, although characterized by a more severe clinical picture and a worse outcome, show less neurobiological abnormalities. © 2012 Elsevier Inc.
Deficit schizophrenia (DS) represents a promising putative clinical subtype of schizophrenia and is characterized by the presence of primary and enduring negative symptoms. Previous studies have often reported a reduced amount of gray matter within prefrontal and temporal cortices in schizophrenia subjects with prevailing negative symptoms; however, the evidence concerning brain structural abnormalities in patients with DS remains controversial.The aim of the present study was to investigate whether patients with DS differed from those with nondeficit schizophrenia (NDS) with respect to the volume of the dorsolateral prefrontal cortex (DLPFC) and hippocampus, two brain areas considered as key regions in the pathogenesis of schizophrenia.In the present study a 3D-T1w MR imaging procedure and an extensive clinical assessment was carried out in 18 patients with schizophrenia, (10 DS and 8 NDS). 3D MPRAGE images were preprocessed with SPM software and two regions of interest (hippocampus and DLPFC) were manually traced to obtain their gray matter volumes.We found a significant reduction of DLPFC in the entire schizophrenia group, with respect to healthy subjects. Although the subgroup of patients with DS had a more severe clinical picture and more impaired social functioning, the DLPFC volume reduction was greater in NDS than in DS patients.In conclusion, according to our structural neuroimaging findings, DS patients, although characterized by a more severe clinical picture and a worse outcome, show less neurobiological abnormalities. © 2012 Elsevier Inc.
Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia
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Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia
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* Investigating the Relationship between White Matter Connectivity and Motivational Circuits in Subjects with Deficit Schizophrenia: A Diffusion Tensor Imaging (DTI) Study (46 views)
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Impact Factor:
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* Brain tissue volumes and relaxation rates in multiple sclerosis: implications for cognitive impairment (345 views) (PDF 31 views)
J Neurol (ISSN: 1432-1459electronic, 0340-5354linking, 0340-5354print), 2019 Feb; 266(2): 361-368.
Impact Factor: 3.853
View Export to BibTeX Export to EndNote
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* Pragmatic abilities in multiple sclerosis: The contribution of the temporo-parietal junction (665 views)
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Impact Factor: 2.851
View Export to BibTeX Export to EndNote
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* Reduced Intracranial Volume in Fabry Disease: Evidence of Abnormal Neurodevelopment? (351 views)
Front Neurol (ISSN: 1664-2295linking, 1664-2295print), 2018 Aug 17; 9(AUG): 672-672.
Impact Factor: 3.508
View Export to BibTeX Export to EndNote
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* Cognitive and functional connectivity alterations in Friedreich's ataxia (1605 views)
Ann Clin Transl Neurol (ISSN: 2328-9503linking, 2328-9503electronic), 2018 Apr 14; 5(6): 677-686.
Impact Factor: 4.649
View Export to BibTeX Export to EndNote
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* Functional connectivity of the ventral tegmental area and avolition in subjects with schizophrenia: a resting state functional MRI study (1070 views)
European Neuropsychopharmacology (ISSN: 0924-977x), 2018 Apr; 28(5): 589-602.
Impact Factor: 4.239
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Lanzillo R, Quarantelli M, Pozzilli C, Trojano M, Amato MP, Marrosu MG, Francia A, Florio C, Orefice G, Tedeschi G, Bellantonio P, Annunziata P, Grimaldi LM, Comerci M, Brunetti A, Bonavita V, Alfano B, Marini S, Brescia Morra V
* No evidence for an effect on brain atrophy rate of atorvastatin add-on to interferon β1b therapy in relapsing-remitting multiple sclerosis (the ARIANNA study) (580 views) (PDF 28 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2016 Aug; 22(9): 1163-1173.
Impact Factor: 4.84
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Mucci A, Dima D, Soricelli A, Volpe U, Bucci P, Frangou S, Prinster A, Salvatore M, Galderisi S, Maj M
* Is avolition in schizophrenia associated with a deficit of dorsal caudate activity? A functional magnetic resonance imaging study during reward anticipation and feedback (523 views)
Psychol Med (ISSN: 0033-2917), 2015 Jan 12; 45(8): 1765-1778.
Impact Factor: 5.491
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Saccà F, Puorro G, Brunetti A, Capasso G, Cervo A, Cocozza S, De Leva M, Marsili A, Pane C, Quarantelli M, Russo CV, Trepiccione F, De Michele G, Filla A, Morra VB
* A randomized controlled pilot trial of lithium in spinocerebellar ataxia type two (1023 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 0340-5354print), 2015 Jan; 262(1): 149-153.
Impact Factor: 3.408
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Patti F, De Stefano M, Lavorgna L, Messina S, Chisari CG, Ippolito D, Lanzillo R, Vacchiano V, Realmuto S, Valentino P, Coniglio G, Buccafusca M, Paolicelli D, D'Ambrosio A, Montella P, Morra VB, Savettieri G, Alfano B, Gallo A, Simone I, Viterbo R, Zappia M, Bonavita S, Tedeschi G
* Lesion load may predict long-term cognitive dysfunction in multiple sclerosis patients (569 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015; 10(3): N/D-N/D.
Impact Factor: 3.057
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Lavorgna L, Bonavita S, Ippolito D, Lanzillo R, Salemi G, Patti F, Valentino P, Coniglio G, Buccafusca M, Paolicelli D, D'Ambrosio A, Bresciamorra V, Savettieri G, Zappia M, Alfano B, Gallo A, Simone I, Tedeschi G
* Clinical And Magnetic Resonance Imaging Predictors Of Disease Progression In Multiple Sclerosis: A Nine-Year Follow-Up Study (719 views) (PDF 253 views)
Mult Scler (ISSN: 1352-4585, 1477-0970), 2014 Feb; 20(2): 220-226.
Impact Factor: 4.822
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Quarantelli M, Palladino O, Prinster A, Schiavone V, Carotenuto B, Brunetti A, Marsili A, Casiello M, Muscettola G, Salvatore M, De Bartolomeis A
* Patients with poor response to antipsychotics have a more severe pattern of frontal atrophy: a voxel-based morphometry study of treatment resistance in schizophrenia (477 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141, 2314-6141electronic), 2014; 2014: 325052-325052.
Impact Factor: 1.579
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Quarantelli M, Salvatore E, Giorgio SM, Filla A, Cervo A, Russo CV, Cocozza S, Massarelli M, Brunetti A, De Michele G
* Default-mode network changes in Huntington's disease: an integrated MRI study of functional connectivity and morphometry (1052 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Aug 19; 8(8): e72159-e72159.
Impact Factor: 3.534
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Pascual B, Prieto E, Arbizu J, Marti-climent JM, Penuelas I, Quincoces G, Zarauza R, Pappata S, Masdeu JC
* Decreased carbon-11-flumazenil binding in early Alzheimer's disease (457 views) (PDF 285 views)
Brain (ISSN: 0006-8950, 1460-2156electronic, 0006-8950linking), 2012 Sep; 135(Pt9): 2817-2825.
Impact Factor: 9.915
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Travaglia A, Pietropaolo A, La Mendola D, Nicoletti VG, Rizzarelli E
* The inorganic perspectives of neurotrophins and Alzheimer's disease (826 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jun; 111: 130-137.
Impact Factor: 3.197
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Fragassi NA, Chiacchio L, Errichiello L, Pappata S, Tedeschi MR, Striano P, Striano S
* Posterior cortical atrophy with prominent alexia without agraphia in a Tourette syndrome (576 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Dec; 32(6): 1129-1133.
Impact Factor: 1.315
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Iavarone A, Lorè E, De Falco C, Milan G, Mosca R, Pappata S, Galeone F, Sorrentino P, Scognamiglio M, Postiglione A
* Dysexecutive performance of healthy oldest old subjects on the Frontal Assessment Battery (500 views)
Aging Clin Exp Res (ISSN: 1594-0667, 1720-8319), 2011 Oct; 23(5-6): 351-356.
Impact Factor: 1.552
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Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J
* Extrastriatal dopamine D 2 receptor binding in Huntington's disease (740 views)
Hum Brain Mapp (ISSN: 1065-9471, 1097-0193electronic, 1065-9471linking), 2011 Oct; 32(10): 1626-1636.
Impact Factor: 5.88
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Gulyas B, Vas A, Toth M, Takano A, Varrone A, Cselenyi Z, Schain M, Mattsson P, Halldin C
* Age and disease related changes in the translocator protein (TSPO) system in the human brain: Positron emission tomography measurements with [11C]vinpocetine (652 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2011 Jun 1; 56(3): 1111-1121.
Impact Factor: 5.895
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Esmaeilzadeh M, Kullingsjo J, Ullman H, Varrone A, Tedroff J
* Regional cerebral glucose metabolism after pridopidine (ACR16) treatment in patients with huntington disease (432 views)
Clin Neuropharmacol (ISSN: 0362-5664), 2011 May; 34(3): 95-100.
Impact Factor: 2.166
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Dinacci D, Tessitore A, Russo AA, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Marcuccio L, Comerci M, Galletti P, Alfano B, Tedeschi G
* BDNF Val66Met polymorphism and brain volumes in multiple sclerosis (500 views) (PDF 255 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Feb; 32(1): 117-123.
Impact Factor: 1.315
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Finnema SJ, Varrone A, Hwang TJ, Gulyas B, Pierson ME, Halldin C, Farde L
* Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain (557 views)
Synapse (ISSN: 0887-4476), 2010 Jul; 64(7): 573-577.
Impact Factor: 2.925
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Cervenka S, Varrone A, Fransen E, Halldin C, Farde L
* PET studies of D2-receptor binding in striatal and extrastriatal brain regions: Biochemical support in vivo for separate dopaminergic systems in humans (656 views)
Synapse (ISSN: 0887-4476), 2010 Jun; 64(6): 478-485.
Impact Factor: 2.925
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Pellecchia MT, Barone PB, Mollica C, Salvatore E, Ianniciello M, Longo K, Varrone A, Vicidomini C, Picillo M, De Michele G, Filla A, Salvatore M, Pappata S
* Diffusion-weighted imaging in multiple system atrophy: a comparison between clinical subtypes (722 views)
Mov Disord (ISSN: 1531-8257, 0885-3185, 0885-3185linking), 2009 Apr 15; 24(5): 689-696.
Impact Factor: 4.014
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Castiglione M, Calafiore M, Costa L, Sortino MA, Nicoletti F, Copani A
* Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice (617 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2008 Sep; 55(4): 560-567.
Impact Factor: 3.383
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Galderisi S, Quarantelli M, Volpe U, Mucci A, Cassano GB, Invernizzi G, Rossi A, Vita A, Pini S, Cassano P, Daneluzzo E, De Peri L, Stratta P, Brunetti A, Maj M
* Patterns of structural MRI abnormalities in deficit and nondeficit schizophrenia (564 views) (PDF 204 views)
Schizophr Bull (ISSN: 0586-7614, 1745-1701electronic, 0586-7614linking), 2008 Mar; 34(2): 393-401.
Impact Factor: 6.592
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Jovanovic H, Lundberg J, Karlsson P, Cerin A, Saijo T, Varrone A, Halldin C, Nordstrom AL
* Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET (650 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2008 Feb 1; 39(3): 1408-1419.
Impact Factor: 5.694
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Takano A, Gulyas B, Varrone A, Karlsson P, Schou M, Airaksinen AJ, Vandenhende F, Tauscher J, Halldin C
* Imaging the norepinephrine transporter with positron emission tomography: Initial human studies with (S, S)-[18F]FMeNER-D2 (517 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Jan; 35(1): 153-157.
Impact Factor: 4.532
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Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (1215 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
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Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (622 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
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Quarantelli M, Lanzillo R, Del Vecchio W, Mollica C, Prinster A, Iadicicco L, Iodice V, Santoro L, Salvatore M
* Modifications of brain tissue volumes in facioscapulohumeral dystrophy (728 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2006 Sep; 32(3): 1237-1242.
Impact Factor: 5.559
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Prinster A, Quarantelli M, Orefice G, Lanzillo R, Brunetti A, Mollica C, Salvatore E, Morra VB, Coppola G, Vacca G, Alfano B, Salvatore M
* Grey matter loss in relapsing-remitting multiple sclerosis: A voxel-based morphometry study (655 views) (PDF 252 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2006 Feb 1; 29(3): 859-867.
Impact Factor: 5.559
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Tedeschi G, Lavorgna L, Russo P, Prinster A, Dinacci D, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone IL, Salvatore M, Bonavita V, Alfano B
* Brain atrophy and lesion load in a large population of patients with multiple sclerosis (601 views) (PDF 269 views)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2005 Jul 26; 65(2): 280-285.
Impact Factor: 5.065
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Hervé D, Molko N, Pappata S, Buffon F, LeBihan D, Bousser MG, Chabriat H
* Longitudinal thalamic diffusion changes after middle cerebral artery infarcts (453 views)
J Neurol Neurosurg Psychiatry (ISSN: 0022-3050), 2005 Feb; 76(2): 200-205.
Impact Factor: 3.122
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Galderisi S, Mucci A, Quarantelli M, Volpe U, Amati G, Alfano B, Maj M
* Structural and functional brain imaging findings in deficit and nondeficit schizophrenia (353 views)
International Journal Of Neuropsychopharmacology (ISSN: 1461-1457), 2004 Jun; 7: N/D-N/D.
Impact Factor: 4.128
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Fujita M, Varrone A, Kim KM, Watabe H, Zoghbi SS, Seneca N, Tipre D, Seibyl JP, Innis RB, Iida H
* Effect of scatter correction on the compartmental measurement of striatal and extrastriatal dopamine D2 receptors using [ 123I]epidepride SPET (427 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 May; 31(5): 644-654.
Impact Factor: 3.935
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Galderisi S, Del Zompo M, Invernizzi G, Pini S, Quarantelli M, Rossi A, Cassano P, Severino G, Stratta P, Vita A, Volpe U, Salvatore M, Maj M
* MRI, neuropsychological and genetic findings in deficit and non-deficit schizophrenia: A multicentre study (317 views)
Eur Psychiat (ISSN: 0924-9338), 2004 Apr; 19: N/D-N/D.
Impact Factor: 1.191
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Kim KM, Varrone A, Watabe H, Shidahara M, Fujita M, Innis RB, Iida H
* Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities (383 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Apr; 44(4): 512-519.
Impact Factor: 4.899
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Quarantelli M, Ciarmiello A, Morra VB, Orefice G, Larobina M, Lanzillo R, Schiavone V, Salvatore E, Alfano B, Brunetti A
* Brain tissue volume changes in relapsing-remitting multiple sclerosis: Correlation with lesion load (556 views) (PDF 252 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2003 Feb; 18(2): 360-366.
Impact Factor: 6.192
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Varrone A, Pappata S, Caracò C, Soricelli A, Milan G, Quarantelli M, Alfano B, Postiglione A, Salvatore M
* Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks (550 views) (PDF 323 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2002 Nov; 29(11): 1447-1454.
Impact Factor: 3.568
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Quarantelli M, Larobina M, Volpe U, Amati G, Tedeschi E, Ciarmiello A, Brunetti A, Galderisi S, Alfano B
* Stereotaxy-based regional brain volumetry applied to segmented MRI: Validation and results in deficit and nondeficit schizophrenia (553 views) (PDF 234 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 17(1): 373-384.
Impact Factor: 5.624
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Alfano B, Brunetti A, Larobina M, Quarantelli M, Tedeschi E, Ciarmiello A, Covelli EM, Salvatore M
Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis (544 views) (PDF 637 views)
J Magn Reson Imaging (ISSN: 1053-1807, 1522-2586electronic, 1053-1807linking), 2000 Dec; 12(6): 799-807.
Impact Factor: 1.302
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Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (798 views) (PDF 614 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1998 Mar; 39(3): 497-499.
Impact Factor: 2.962
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Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M
Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (730 views) (PDF 707 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1997 Jan; 37(1): 84-93.
Impact Factor: 3.012
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44 Records (41 excluding Abstracts).
Total impact factor: 191.87 (183.017 excluding Abstracts).
Total 5 year impact factor: 215.031 (202.439 excluding Abstracts).
Total impact factor: 191.87 (183.017 excluding Abstracts).
Total 5 year impact factor: 215.031 (202.439 excluding Abstracts).
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