Imaging techniques for assessment of coronary flow reserve(540 views) Petretta M, Acampa W, Zampella E, Assante R, Petretta MP, Cuocolo R, Fabiani I, Della Rattal GL, Perrone-Filardi P, Cuocolo A
Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
Department of Biomorphological and Functional Sciences, University Federico II, Via Sergio Pansini, 5, I-80131 Naples, Italy
Institute of Biostructures and Bioimages, National Council of Research, Naples, Italy
References: Not available.
Imaging techniques for assessment of coronary flow reserve
The assessment of coronary flow reserve (CFR) may be useful for the functional evaluation of coronary artery disease (CAD). Invasive techniques, such as intracoronary Doppler ultrasound and pressure-derived method, directly assess CFR velocity and fractional flow reserve. Positron emission tomography (PET) has emerged as an accurate noninvasive technique to quantify CFR. Nevertheless, this approach has not been applied to routine studies because of its high cost and complexity. Recently, attempts to estimate CFR with single-photon emission computed tomography (SPECT) tracers have been made in order to obtain, with noninvasive methods, data for quantitative functional assessment of CAD. This review analyzes the relative merit and limitations of CFR measurements by cardiac imaging techniques and describes the potential clinical applications.
Imaging techniques for assessment of coronary flow reserve