Imaging techniques for assessment of coronary flow reserve(402 views) Petretta M, Acampa W, Zampella E, Assante R, Petretta MP, Cuocolo R, Fabiani I, Della Rattal GL, Perrone-Filardi P, Cuocolo A
Department of Clinical Medicine, Cardiovascular and Immunological Sciences, University Federico II, Naples, Italy
Department of Biomorphological and Functional Sciences, University Federico II, Via Sergio Pansini, 5, I-80131 Naples, Italy
Institute of Biostructures and Bioimages, National Council of Research, Naples, Italy
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Johnson, P. C., Review of previous studies and current theories of autoregulation (1964) Circ Res, 15 (SUPPL.), pp. 2-
Shaw, R. F., Mosher, P., Ross Jr., J., Physiologic principles of coronary perfusion (1962) J Thorac Cardiovasc Surg, 44, pp. 608-616
Gould, K. L., Lipscomb, K., Effects of coronary stenoses on coronary flow reserve and resistance (1974) Am J Cardiol, 34, pp. 48-55
Gould, K. L., Kirkeeide, R. L., Buchi, M., Coronary flow reserve as a physiologic measure of stenosis severity (1990) Journal of the American College of Cardiology, 15 (2), pp. 459-474
Kern, M. J., Coronary physiology revisited: Practical insights from the cardiac catheterization laboratory (2000) Circulation, 101 (11), pp. 1344-1351
Strauer, B. E., The significance of coronary reserve in clinical heart disease (1990) J Am Coll Cardiol, 15, pp. 775-783
Pijls, N. H. J., Van Son, J. A. M., Kirkeeide, R. L., De Bruyne, B., Gould, K. L., Experimental basis of determining maximum coronary, myocardial, and collateral blood flow by pressure measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty (1993) Circulation, 87 (4), pp. 1354-1367
Blows, L. J., Redwood, S. R., The pressure wire in practice (2007) Heart, 93 (4), pp. 419-422. , DOI 10. 1136/hrt. 2005. 066837
Drake-Holland, A. J., Laird, J. D., Noble, M. I. M., Oxygen and coronary vascular resistance during autoregulation and metabolic vasodilatation in the dog (1984) Journal of Physiology, VOL. 348, pp. 285-299
Doucette, J. W., Corl, P. D., Payne, H. M., Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity (1992) Circulation, 85, pp. 1899-1911
Labovitz, A. J., Anthonis, D. M., Cravens, T. L., Kern, M. J., Validation of volumetric flow measurements by means of a Doppler-tipped coronary angioplasty guide wire (1993) American Heart Journal, 126 (6), pp. 1456-1461. , DOI 10. 1016/0002-8703 (93) 90545-K
Miller, D. D., Donohue, T. J., Younis, L. T., Correlation of pharmacological 99mTc-sestamibi myocardial perfusion imaging with poststenotic coronary flow reserve in patients with angiographically intermediate coronary artery stenoses (1994) Circulation, 89, pp. 2150-2160
McGinn, A. L., White, C. W., Wilson, R. F., Interstudy variability of coronary flow reserve: Influence of heart rate, arterial pressure, and ventricular preload (1990) Circulation, 81 (4), pp. 1319-1330
Rossen, J. D., Winniford, M. D., Effect of increases in heart rate and arterial presure on coronary flow reserve in humans (1993) Journal of the American College of Cardiology, 21 (2), pp. 343-348
Vicario, M. L. E., Cirillo, L., Storto, G., Pellegrino, T., Ragone, N., Fontanella, L., Petretta, M., Cuocolo, A., Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (2005) Journal of Nuclear Medicine, 46 (9), pp. 1438-1443
Brunken, R. C., Challenges for measurement of myocardial perfusion and perfusion reserve by SPECT imaging (2007) Journal of Nuclear Cardiology, 14 (2), pp. 145-149. , DOI 10. 1016/j. nuclcard. 2007. 01. 034, PII S1071358107001067
Gullberg, G. T., Di, B. E. V. R., Sinusas, A. J., Estimation of coronary flow reserve: Can SPECT compete with other modalities? (2001) Journal of Nuclear Cardiology, 8 (5), pp. 620-625. , DOI 10. 1067/mnc. 2001. 118121
Bergmann, S. R., Herrero, P., Markham, J., Weinheimer, C. J., Walsh, M. N., Noninvasive quantitation of myocardial blood flow in human subjects with oxygen-15-labeled water and positron emission tomography (1989) Journal of the American College of Cardiology, 14 (3), pp. 639-652
Araujo, L. I., Lammertsma, A. A., Rhodes, C. G., Noninvasive quantification of regional myocardial blood flow in coronary artery disease with oxygen-15-labeled carbon dioxide inhalation and positron emission tomography (1991) Circulation, 83, pp. 875-885
Uren, N. G., Camici, P. G., Melin, J. A., Effect of aging on myocardial perfusion reserve (1995) J Nucl Med, 36, pp. 2032-2036
Kaufmann, P. A., Gnecchi-Ruscone, T., Di Terlizzi, M., Coronary heart disease in smokers: Vitamin C restores coronary microcirculatory function (2000) Circulation, 102, pp. 1233-1238
Uren, N. G., Melin, J. A., De, B. B., Relation between myocardial blood flow and the severity of coronary artery stenosis (1994) N Engl J Med, 330, pp. 1782-1788
Gould, K. L., Noninvasive assessment of coronary stenoses by myocardial perfusion imaging during pharmacologic coronary vasodilatation. I. Physiologic basis and experimental validation (1978) American Journal of Cardiology, 41 (2), pp. 267-278. , DOI 10. 1016/0002-9149 (78) 90165-0
Muhling, O. M., Dickson, M. E., Zenovich, A., Huang, Y., Wilson, B. V., Wilson, R. F., Anand, I. S., Wilke, N. M., Quantitative magnetic resonance first-pass perfusion analysis: Inter- and intraobserver agreement (2001) Journal of Cardiovascular Magnetic Resonance, 3 (3), pp. 247-256. , DOI 10. 1081/JCMR-100107473
Yang, E. H., Lerman, A., Angina pectoris with a normal coronary angiogram (2005) Herz, 30 (1), pp. 17-25. , DOI 10. 1007/s00059-005-2641-5
Beltrame, J. F., Horowitz, J. D., ST elevation secondary to microvascular dysfunction (1999) J Am Coll Cardiol, 34, pp. 312-313
Lanza, G. A., Manzoli, A., Pasceri, V., Ischemic-like ST-segment changes during Holter monitoring in patients with angina pectoris and normal coronary arteries but negative exercise testing (1997) Am J Cardiol, 79, pp. 1-6
Galassi, A. R., Crea, F., Araujo, L. I., Lammertsma, A. A., Pupita, G., Yamamoto, Y., Rechavia, E., Lewington, G., Comparison of regional myocardial blood flow in syndrome X and one-vessel coronary artery disease (1993) American Journal of Cardiology, 72 (2), pp. 134-139. , DOI 10. 1016/0002-9149 (93) 90148-6
Van Den Heuvel, A. F., Van Veldhuisen, D. J., Van Der Wall, E. E., Regional myocardial blood flow reserve impairment and metabolic changes suggesting myocardial ischemia in patients with idiopathic dilated cardiomyopathy (2000) J Am Coll Cardiol, 35, pp. 19-28
Murthy, V. L., Naya, M., Foster, C. R., Improved cardiac risk assessment with noninvasive measures of coronary flow reserve (2011) Circulation, 124, pp. 2215-2224
Imaging techniques for assessment of coronary flow reserve
The assessment of coronary flow reserve (CFR) may be useful for the functional evaluation of coronary artery disease (CAD). Invasive techniques, such as intracoronary Doppler ultrasound and pressure-derived method, directly assess CFR velocity and fractional flow reserve. Positron emission tomography (PET) has emerged as an accurate noninvasive technique to quantify CFR. Nevertheless, this approach has not been applied to routine studies because of its high cost and complexity. Recently, attempts to estimate CFR with single-photon emission computed tomography (SPECT) tracers have been made in order to obtain, with noninvasive methods, data for quantitative functional assessment of CAD. This review analyzes the relative merit and limitations of CFR measurements by cardiac imaging techniques and describes the potential clinical applications.
Imaging techniques for assessment of coronary flow reserve