Software development of digital MRI brain phantom

Software development of digital MRI brain phantom

Research areas: Quantitative Imaging,

Keywords: MRI segmentation, relaxometry, phantom, quantitative magnetic color imaging, multiparametric, Atrophy, Cognitive Impairment, Quantitative Imaging

Contact person: Marco Comerci, marco.comerci

ibb.cnr.it

Actors: Anna Prinster, anna.prinster

ibb.cnr.it, Marco Comerci, marco.comerci

ibb.cnr.it,

Description:
This activity comprises the development and tuning of a software tool that can produce digital MRI brain phantoms, which simulate relaxation rate distributions of real target studies.

Digital brain phantoms are needed to assess the performance of segmentation methods, providing a gold standard, against which compare the segmentation produced by the softwares.

The phantom is composed of 17 tissue compartment and an optional abnormal white matter compartment, simulating MS lesions.

The software has four head models, two normal volunteers and two MS models. Currently the software allow to manually specify the mean signal intensities of the compartments, orientation, position, noise and other parameters or derive them from a target study, segmented automatically by our segmentation software, optionally warping the phantom to the target study.

Four sample phantoms, one for each model, and the custom phantoms are available for download at this link.

Figures:

Physical model: R1 and compartments

Selected papers:
QMCI:

1) Multiparametric display of spin-echo data from MR studies of brain (PDF restricted )

Alfano B , Brunetti A , Arpaia M, Ciarmiello A, Covelli EM, Salvatore M , J Magn Reson Imaging, 1995 Mar-Apr;5 (2):217-225

2) Simultaneous display of multiple MR parameters with "quantitative magnetic color imaging" (PDF restricted )

Alfano B , Brunetti A , Ciarmiello A, Salvatore M , J Comput Assist Tomogr, 1992 Jul-Aug;16 (4):634-640

Segmentation:

3) Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis (PDF restricted )

Alfano B , Brunetti A , Larobina M , Quarantelli M , Tedeschi E , Ciarmiello A, Covelli EM, Salvatore M , J Magn Reson Imaging, 2000 Dec;12 (6):799-807

4) Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (PDF restricted )

Alfano B , Quarantelli M , Brunetti A , Larobina M , Covelli EM, Tedeschi E , Salvatore M , Magn Reson Med, 1998 Mar;39 (3):497-499

5) Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (PDF restricted )

Alfano B , Brunetti A , Covelli EM, Quarantelli M , Panico M , Ciarmiello A, Salvatore M , Magn Reson Med, 1997 Jan;37 (1):84-93

Phantom:

6) An MRI digital brain phantom for validation of segmentation methods (PDF restricted )

Alfano B , Comerci M , Larobina M , Prinster A , Hornak JP, Selvan SE, Amato U, Quarantelli M , Tedeschi G, Brunetti A , Salvatore M , Med Image Anal, 2011 Jun;15 (3):329-339

Software development of digital MRI brain phantom Your query: ([atitle, adesc, keywords] "MRI segmentation" OR [atitle, adesc, keywords] "relaxometry" OR [atitle, adesc, keywords] "quantitative magnetic color imaging" OR [atitle, adesc, keywords] "multiparametric" OR [atitle, adesc, keywords] "Cognitive Impairment") AND NOT [id] = 74

Your query: ([atitle, adesc, keywords] "MRI segmentation" OR [atitle, adesc, keywords] "relaxometry" OR [atitle, adesc, keywords] "quantitative magnetic color imaging" OR [atitle, adesc, keywords] "multiparametric" OR [atitle, adesc, keywords] "Cognitive Impairment") AND NOT [id] = 74

Software development of digital MRI brain phantom Your query: [btitle, abstract, keywords] "MRI segmentation" OR [btitle, abstract, keywords] "relaxometry" OR [btitle, abstract, keywords] "quantitative magnetic color imaging" OR [btitle, abstract, keywords] "multiparametric" OR [btitle, abstract, keywords] "Cognitive Impairment"

Your query: [btitle, abstract, keywords] "MRI segmentation" OR [btitle, abstract, keywords] "relaxometry" OR [btitle, abstract, keywords] "quantitative magnetic color imaging" OR [btitle, abstract, keywords] "multiparametric" OR [btitle, abstract, keywords] "Cognitive Impairment"

Last modified by Marco Comerci on Monday 14 December 2020, 19:49:59
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IBB website - v.1.0.338 - 17/09/2024 - by Marco Comerci. Copyright 2024 © CNR Istituto di Biostrutture e Bioimmagini. Page loaded at 16/10/2024 03:18:38.