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NameGiovanni Nicola Roviello
AreaResearch&Development
PositionResearcher
Work siteNaples - Castellino
AddressVia Pietro Castellino 111, 80131 Naples - Italy
E-mailgiroviel@unina.it
Web pagehttps: / /www.researchgate.net /profile /Giovanni-Roviello
▼    Other Diseases
▼    Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼    Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼    Bioactive peptide-membrane assemblies
No results.
▼    Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    Chemical protein synthesis and modification for biomedical applications
▼    Comparison of noninvasive cardiac imaging modalities in patients with myocardial infarction
▼    Structural and functional studies of virulence factors in Mycobacterium tuberculosis infection
▼    Assessment of the cardiac risk and its temporal variation
▼    Evaluation of new molecular probes by preclinical imaging
▼    Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
▼    Phenotyping of murine models by preclinical imaging
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
▼    Drug discovery by mirror-image phage display
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications
▼    Technologies and techniques in medicine
▼    Cancer Diseases
▼    Gadd45 beta and its implication in chronic inflammation
▼    Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
▼    Characterization of the KCTD protein family: key factors in several biological processes
▼    Characterization of neurotoxic and neuroprotective factors by using computational methodologies
▼    Monoclonal Antibodies for therapeutic and diagnostic applications
▼    Targeted Drug Delivery by integrin avb3 antagonist
▼    Chemical protein synthesis and modification for biomedical applications
▼    Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    Imaging Tumor Acidosis
▼    Bioactive peptide-membrane assemblies
No results.
▼    Carbonic Anhydrase IX as target for the development of new anti-tumour drugs
▼    Clinical Oncology
▼    Translational Molecular Imaging in Cancer
▼    Molecular imaging for personalized therapy in oncology
▼    Modeling radiation induced normal tissue effects
▼    Evaluation of new molecular probes by preclinical imaging
▼    Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
▼    Brain segmentation for radiation oncology application
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
▼    Drug discovery by mirror-image phage display
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications
▼    Small molecules and peptides/modified peptides for diagnostic, therapeutic and biotechnological applications
▼    Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    New peptide–based molecules as NGF mimetics in the therapy of neurological dysfunctions
▼    Peptide-based molecules for αvβ3 integrin modulation in Th17 cells-dependent demyelinating diseases
▼    Development of integrin subtypes selective ligands: from a first rationally designed peptide to a wide range of molecules
▼    Design of New FSHR-Specific Peptides for therapeutic and diagnostic applications
▼    New synthetic molecules for active targeting of multifunctional theranostic nanosystems
▼    Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications
▼    Galectins: Structure, function and therapeutic potential inhibitors
▼    Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives
▼    A multi-targeting approach to fight COVID-19
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications
▼    Drug discovery by mirror-image phage display
▼    Peptides of therapeutic interest with antimicrobial and/ or antitumoral activity
▼    Analysis of Sam domain druggability through computational and experimental studies
▼    Targeting Sam-Sam interactions mediated by EphA2 receptor: design and evaluation of peptide inhibitors
▼    Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
▼    Plant polypeptides as natural enhancers of biostimulation
▼    Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
▼    Design and screening of molecular repertoires as a source for new bioactive compounds
▼    Targeting Of Protein-Protein Interactions For Therapeutic Purposes
▼    Structure and function of proteins involved in physio-pathologic processes
▼    Carbonic Anhydrase IX as target for the development of new anti-tumour drugs
▼    Biomolecules able to modulate the VEGF-dependent angiogenesis
▼    A multi-targeting approach to fight COVID-19
▼    Galectins: Structure, function and therapeutic potential inhibitors
▼    Carbonic Anhydrase family as target for rational drug design
▼    Characterization of the KCTD protein family: key factors in several biological processes
▼    Chemical protein synthesis and modification for biomedical applications
▼    Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives
▼    Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications
▼    Structural characterization of the porphyrins/proteasome interaction
▼    Axl and Gas6 targeting for therapeutic and diagnostic applications
▼    Drug discovery by mirror-image phage display
▼    Analysis of Sam domain druggability through computational and experimental studies
▼    Targeting Sam-Sam interactions mediated by EphA2 receptor: design and evaluation of peptide inhibitors
▼    Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
▼    Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases
▼    Biochemical and functional characterization of Protein-Protein and DNA-protein Interaction networks in physio/pathological events
▼    Biochemical and structural insights on Chromatin Assembly Factor 1 in physio/pathological events
▼    Targeting Of Protein-Protein Interactions For Therapeutic Purposes
▼    Structural and electronic properties of nucleic acids

Curriculum Vitae Dr. Giovanni N. Roviello, Ph.D.

Ist Level Researcher at Italian National Council for Research (CNR), Institute of Biostructure and Bioimaging (IBB)

 

E-mails: giroviel@unina.it; giovanni.roviello@cnr.it;

H-index: 26 (Scopus), 26 (WoS),  27 (Google Scholar)

ORCID ID: https://orcid.org/0000-0001-6065-2367

https://www.scopus.com/authid/detail.uri?authorId=35580154100
https://www.reviewercredits.com/user/giovrovi/
CNR scientific leader for EU project NoBiasFluors, H2020, 872331
https://cordis.europa.eu/project/id/872331


 

June 2002: Degree in Chemistry cum laude. Federico II University, Naples – Italy

 

June 2002-Jan. 2003: partecipation in the European Research Project Centre for Design and Structure in Biology (CDSB) -Jena (Germany), Istituto di Biostrutture e Bioimmagini del CNR, Napoli/IMB-Institut fr Molekulare Biotechnologie, Jena (Germany).

 

November 2002-January 2006: Ph. D. in Biotechnology Federico II University, Naples - Italy. Thesis: PNA/DNA chimeras for biotechnological applications.

 

March 2005-June 2005: Research activity at the Georg-August-Universität of Goettingen (Germany).

 

April 2006-May 2006: scientific collaboration with RiboVax Biotechnologies S. A.

 

June 2006-November 2006: scientific collaboration with Biostructure and Bioimaging Institute of National Council of Research (IBB-CNR).

 

November 2006-today: CNR Researcher at Biostructure and Bioimaging Institute of National Council of Research.

 

 1st April 2017 -31st May 2017: visiting researcher at UCD-Dublin /O'Brien Science Centre and collaboration with Kelada Pharmachem Ltd (H2020 Marie Sklowdowska-Curie RISE grant - ChemoEnz).

 

1st September 2018 -30 November 2018: supervisor of  Dr. Marta Fik (post-doc activity at IBB-CNR, SONATINA 1 Research Programme no. 2017/24/C/ST5/00181) and Martyna Szymanska (doctorate activity at IBB-CNR, CHEMINTER Research Programme no. POWR.03.02.00-00-IO26/16), both from Department of Bioinorganic Chemistry, Faculty of Chemistry - Adam Mickiewicz University in Poznan, POLAND. 

 

IBB CNR Research Coordinator for the scientific collaborations with Adam Mickiewicz University - Poznan, POLAND, (Agreement prot n. IBB CNR 0001777 26/09/2018)

 

7th January 2019 -28th January 2019: visiting researcher at Friedrich-Alexander University - Erlangen, Germany and collaboration with prof. Andriy Mokhir (Department Chemie und Pharmazie). CNR Short Term Mobility programme (STM 2018 prot.n. CNR0067802/2018 - 15/10/2018)

 

25th October 2021 - Scientific Consultant for the Research Project 'Synthesis and biological evaluation of unnatural alpha-amino acids and peptide-based systems for biomedical strategies' (Scientific Committeee of Republic of Armenia; Code 21T-1D057, start date 25-10-2021, duration 3 years)  


January 2023-2025: Project leader/coordinator of  the international research project “Synthetic alpha-amino acids and peptide-based systems for anticancer strategies”; Joint research Project – CNR/MESRA (Armenia) cooperation (CNR Prot. N. 19140 del 20230125 (2023-CNR0A00-0019140))


Teaching activities:

September 2004-September 2006: Lecturer at Chemistry introductive course, Faculty of Sciences Federico II University of Naples.

November 2007-November 2010 and May 2012 - November 2012: Lecturer in Chemistry, Federico II University of Naples.(Facoltà di Biotecnologie; Facoltà di Agraria; Chimica Generale ed Inorganica) 

November 2010-March 2012: Lecturer in Chemistry, Parthenope University of Naples. (Facoltà di Scienze e Tecnologie; Chimica Generale ed Inorganica con Laboratorio)

January 2019: Lecturer in Chemistry, Friedrich-Alexander University - Erlangen, Germany ('Bioanorganische Chemie III' CME3-B5, M.Sc. Chemistry WS 18/19)

April 2021: Teaching activity (15 h) for the Ph.D. students Adam Mickiewicz University - Poznan, POLAND (Faculty of Chemistry): Advanced Course on Nucleic acid chemistry for Biomedical application

June 2021: participation in the Evaluation Committee for the doctoral candidates of Adam Mickiewicz University - Poznan, POLAND (Faculty of Chemistry): AMU University - EU European Social Fund

Mar 2022-today: Lecturer for the course "The Biotechnological Basis of Rehabilitation'' (45 academic hours) for the Georgian State Teaching University of Physical Education and Sports (Tbilisi, Georgia; Level of Education: Bachelor's Level;  Education Program: Physical Medicine and Rehabilitation) 


Project Leaderships:

Jan 2014-Oct 2020: New strategies for medical and molecular diagnosis and for food traceability and monitoring (Nuove strategie per la diagnostica medica e molecolare e per la tracciabilita' ed il monitoraggio dei prodotti alimentari) 4.049.300,00 € (104.000,00 € IBB-CNR, Roviello G. scientific project leader for CNR) Italian Ministry for University and Research (MIUR) - Campania Region POR-FESR 2014-2020 project PON03PE_0060_4; OR5; n. prot 668 released by Regione Campania 24 Dec 2018;

 

Jan 2020-Dec 2024:    NoBiasFluors (Non-biased fluorescent dyes as markers of drugs for optical in cellulo and in vivo imaging)            669.200,00 € (92.000,00 € IBB-CNR, Roviello G. scientific project leader for CNR). European Union EU - H2020-MSCA-RISE-2019 number: 872331.

 

Sept 2012-Apr 2014: Synthesis of Chemiluminescent compounds for diagnostic applications (Industrial Research Project) funded by ALTERGON Italia SRL, 20.000 € (IBB CNR-Roviello G PI);   prot. IBB CNR N. 0001626; prot. IBB CNR N. 0001024

 

Apr 2015-Dec 2016: New nucleopeptide-based systems for diagnostic applications (Nuovi sistemi nucleopeptidici per applicazioni diagnostiche) funded by Regione Campania, Italy; 15.000,00 € (IBB CNR - Roviello G, PI);

 

January 2023-2025: Project leader/coordinator of  the international research project “Synthetic alpha-amino acids and peptide-based systems for anticancer strategies”; 10.000,00 € IBB-CNR, Roviello G. PI for CNR; Joint research Project – CNR/MESRA (Armenia) cooperation (CNR Prot. N. 19140 del 20230125 (2023-CNR0A00-0019140))

 

CNR scientific leader for the project 'Synthesis and biological evaluation of unnatural alpha-amino acids and peptide-based systems for biomedical strategies' unilaterally funded by the Science Committee of the Republic of Armenia (Code 21T-1D057; 28th Oct 2021 -28th Oct 2024)


Membership in scientific/organizing committees: 1- 3rd International Conference of Young Scientists – Chemistry Today - 2013, Georgia; 2- 4th International Conference of Young Scientists - Chemistry Today - 2014, Armenia; 3- Novel Strategies in Anticancer Therapy and Diagnostics - Workshop in the frame of the POR FESR 2014 - 2020 - 2019, Italy 4-I Chimici per le Biotecnologie- Workshop Federico II University, Naples, 2023 -Italy https://www.chimiciperlebiotecnologie.it/workshop-2023


Other appointments:

 

May 2012: achievement of the title of Professor honoris causa in Medicinal Chemistry, Geomedi Medical University of Tbilisi - Georgia.

May 2012: Nomination as an Expert consultant in the field of Chemistry for Chemical, Biological, Radiological and Nuclear (CBRN) Centres of Excellence (CoE).

November 2012-September 2016 Supervisor for the General Chemistry Laboratory, Department of Biological Sciences, Parthenope University of Naples.

June 2012: Poster Prize awarded at COST Conference Personalised Medicine: Better Healthcare for the Future 17-22 Giugno 2012, Larnaca, Cipro

January 2014-July 2016: participant in the Caspases Project supported by Regione Sardegna


Italian National Scientific Qualification (Abilitazione Scientifica Nazionale): habilitation as "Associate Professor" (II fascia)

2017 - 03/C1 - Organic Chemistry

2017 - 03/B1 - Inorganic & General Chemistry

2017 - 05/E1 - General Biochemisty

 habilitation as "Full Professor" (I fascia):

2021 - 03/C1 - Organic Chemistry



Papers selected for Journal's cover page:


1)     Roviello V, Gilhen-Baker M, Vicidomini C, Roviello GN* The healing power of clean rivers: in silico evaluation of the antipsoriatic potential of apiin and hyperoside plant metabolites contained in river waters.§ Int J Environ Res Public Health. 2022 . DOI: 10.3390/ijerph19052502

§selected for the cover of the Issue 5,  Volume 19 (March-1 2022 – 656 articles) https://www.mdpi.com/1660-4601/19/5


Vicidomini, C.; Roviello, V.; Roviello, G.N. In Silico Investigation on the Interaction of Chiral Phytochemicals from Opuntia ficus-indica with SARS-CoV-2 Mpro. Symmetry 2021, 13, 1041. https://doi.org/10.3390/sym13061041§§


§§selected as paper recommended by the Scientific Editor ('Editor's choice' appointment)


BOOKS:

Roviello, Giovanni N., and Caterina Vicidomini. 2023. Potential Anti-SARS-CoV-2 Molecular Strategies. ISBN 978-3-0365-6963-5; (hardback); ISBN 978-3-0365-6962-8 (PDF); DOI: 10.3390/books978-3-0365-6962-8;  MDPI St. Alban-Anlage 66 4052 Basel, Switzerland

Editorial Board Member, Modern Issues of Medicine and Management, publisher: Geomedi University, Georgia, ISSN 1512-4169

Topic Editor:

Molecules, publisher: MDPI, ISSN 1420-3049

 

Guest Editor:

Molecules, publisher: MDPI, ISSN 1420-3049

Biomolecules, publisher: MDPI, ISSN 2218-273X

Pharmaceuticals, publisher: MDPI, ISSN 1424-8247 

Inorganics, publisher: MDPI, ISSN 2304-6740

Membership in conference scientific/organizing committees: 


1- 3rd International Conference of Young Scientists – Chemistry Today - 2013, Georgia;

2- 4th International Conference of Young Scientists - Chemistry Today -  2014, Armenia;

3- Novel Strategies in Anticancer Therapy and Diagnostics - Workshop in the frame of the POR FESR 2014 - 2020  - 2019, Italy.

4- Towards Novel Anticancer Strategies: It’s Time to Build a New Research Community - Workshop in the frame of the POR FESR 2014 - 2020  - 2019, Italy.

https://sites.google.com/view/anti-cancer-strategy/home

5-I Chimici per le Biotecnologie- Workshop Federico II University, Naples, 2023 -Italy https://www.chimiciperlebiotecnologie.it/workshop-2023




Some conferences and achievements:

Aug 2011 EBSA bursary by European Biophysical Societies\' Association for the attendance to the \"8th EBSA European Biophysics Congress\" August 23rd–27th 2011, Budapest, Hungary, as reported in Eur Biophys J (2011) 40 (Suppl 1):S11

Oct 2011 CNR bursary – Individual Training Plan for the attendance to the \"ESF-COST High-Level Research Conference - Systems Chemistry III 23-28 October 2011 – Amoudara – Crete, Greece. (formazione individuale CNR Quota A; prot. N. 0009547 - 31/01/11).

 


Referee

Journal of Physical Chemistry - American Chemical Society, Bioconjugate Chemistry - American Chemical Society, Molecular Biology and Evolution - Oxford University Press, International Journal of Biological Macromolecules - Elsevier, New Journal of Chemistry - Royal Society of Chemistry,  Current Medicinal Chemistry, Bentham Science Publishers; Current Pharmaceutical Design, Bentham Science Publishers; Medicinal Chemistry, Bentham Science Publishers; International Journal of Nanomedicine, Dove Medical Press; International Journal of Pharmaceutics, Elsevier; Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis.

 



 Memberships:

EPS (European Peptide Society), member since 2008.

EFB (European Federation of Biotechnology), member since 2016

Reviewer Credits, member since  2017

 SCI (Società Chimica Italiana)

 

 

 

 

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* Deciphering the Relationship between SARS-CoV-2 and Cancer (2 views)
Costanzo M, De Giglio MAR, Roviello GN
International Journal Of Molecular Sciences, 2023 Apr; 24: 7803-7803.
Impact Factor: 6.208
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* Nucleic Acid Probes in Bio-Imaging and Diagnostics: Recent Advances in ODN-Based Fluorescent and Surface-Enhanced Raman Scattering Nanoparticle and Nanostructured Systems (4 views)
Sardaru M-C, Marangoci N-L, Palumbo R, Roviello GN, Rotaru A
Molecules, 2023 Apr; 28: 3561-3561.
Impact Factor: 4.927
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* Targeting Mitochondrial Therapy in the Regulation of HPV Infection and HPV-Related Cancers (7 views)
Cruz-gregorio A, Aranda-rivera AK, Roviello GN, Pedraza-chaverri J
Pathogens (ISSN: 2076-0817linking), 2023 Mar 2; 12(3): 402-417.
Impact Factor: 4.531
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* Interaction of Laurusides 1 and 2 with the 3C-like Protease (Mpro) from Wild-Type and Omicron Variant of SARS-CoV-2: A Molecular Dynamics Study (8 views)
Autiero I, Roviello GN
International Journal Of Molecular Sciences, 2023 Mar; 25: 5511-5511.
Impact Factor: 6.208
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* Potential Anti-SARS-CoV-2 Molecular Strategies (10 views)
Vicidomini C, Roviello GN
Molecules (ISSN: 1420-3049linking), 2023 Feb 24; 28(5): 2118-2123.
Impact Factor: 4.9
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* Exploring the Protective Effect of Food Drugs against Viral Diseases: Interaction of Functional Food Ingredients and SARS-CoV-2, Influenza Virus, and HSV (13 views)
Ricci A, Roviello GN
Life, 2023 Feb; 13: 402-417.
Impact Factor: 3.253
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* Graffiti Paint on Urban Trees: A Review of Removal Procedures and Ecological and Human Health Considerations (4 views)
Roviello V, Gilhen-baker M, Roviello GN
Sustainability, 2023 Feb; 15: 4022-4037.
Impact Factor: 3.889
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* Self‑assembly of thyminyl l‑tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems (13 views)
Scognamiglio PL, Riccardi C, Palumbo R, Gale TF, Musumeci D, Roviello GN
Journal Of Nanostructure In Chemistry, 2023 Feb; N/D: N/D-N/D.
Impact Factor: 8
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* The Potential Role of Vaccines in Preventing Antimicrobial Resistance (AMR): An Update and Future Perspectives (5 views)
Costanzo V, Roviello GN
Vaccines, 2023 Feb; 11: 333-353.
Impact Factor: 4.961
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* Synthesis, Characterization, and Study of Catalytic Activity of Chiral Cu(II) and Ni(II) Salen Complexes in the α-Amino Acid C-α Alkylation Reaction (7 views)
Tovmasyan AS, Mkrtchyan AF, Khachatryan HN, Hayrapetyan MV, Hakobyan RM, Poghosyan AS, Tsaturyan AH, Minasyan EV, Maleev VI, Larionov VA, Ayvazyan AG, Shibata N, Roviello GN, Saghyan AS
Molecules, 2023 Jan 25; 28: 1180-1196.
Impact Factor: 4.927
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* New N4-Donor Ligands as Supramolecular Guests for DNA and RNA: Synthesis, Structural Characterization, In Silico, Spectrophotometric and Antimicrobial Studies (23 views)
Ewert E, Pospieszna-markiewicz I, Szymańska M, Kurkiewicz A, Belter A, Kubicki M, Patroniak V, Fik-jaskółka MA, Roviello GN
Molecules (ISSN: 1420-3049linking), 2023 Jan; 28: 400-421.
Impact Factor: 4.927
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* The Role of Nutrition and Forest-Bathing in the Physical Rehabilitation of Physically Inactive Patients: From the Molecular Aspects to New Nature-Inspired Techniques (21 views)
Baker S, Gilhen-baker M, Roviello GN
International Journal Of Environmental Research And Public Health, 2023 Jan; 20: 793-805.
Impact Factor: 4.614
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* Exploring the relationship between G-quadruplex nucleic acids and plants: from plant G-quadruplex function to phytochemical G4 ligands with pharmaceutic potential (8 views)
Falanga AP, Terracciano M, Oliviero G, Roviello GN, Borbone N
Pharmaceutics, 2022 Nov 4; N/D: N/D-N/D.
Impact Factor: 6.525
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* Cytosine-rich oligonucleotides incorporating a non-nucleotide loop: A further step towards the obtainment of physiologically stable i-motif DNA (8 views)
Greco F, Marzano M, Falanga AP, Terracciano M, Piccialli G, Roviello GN, D , #xerrico S, Borbone N, Oliviero G
Int J Biol Macromol (ISSN: 0141-8130linking), 2022 Oct 31; 219: 626-636.
Impact Factor: 8.025
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* New Cu(i) square grid-type and Ni(ii) triangle-type complexes: synthesis and characterization of effective binders of DNA and serum albumins (8 views)
Szymańska M, Kubicki M, Roviello GN, Consiglio G, Fik-jaskółka MA, Patroniak V
Dalton Transactions, 2022 Oct 13; N/D: N/D-N/D.
Impact Factor: 4.569
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* Willardiine and Its Synthetic Analogues: Biological Aspects and Implications in Peptide Chemistry of This Nucleobase Amino Acid (12 views)
Palumbo R, Omodei D, Vicidomini C, Roviello GN
Pharmaceuticals, 2022 Oct 10; 15: 1243-1243.
Impact Factor: 5.2
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* CD, UV, and In Silico Insights on the Effect of 1, 3-Bis(1'-uracilyl)-2-propanone on Serum Albumin Structure (7 views)
Greco F, Falanga AP, Terracciano M, D , #xambrosio C, Piccialli G, Oliviero G, Roviello GN, Borbone N
Biomolecules (ISSN: 2218-273xlinking), 2022 Aug 3; 12(8): 1071-1088.
Impact Factor: 6.064
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* Tree-inhabiting polypore fungi as sources of a cornucopia of bioactive compounds (20 views) (PDF 7 views)
Costanzo V, Gilhen-baker M, Beresford-kroeger D, Roviello GN
Future Microbiol (ISSN: 1746-0913linking), 2022 Aug; 17: 899-902.
Impact Factor: 3.553
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* Nucleic Acids as Biotools at the Interface between Chemistry and Nanomedicine in the COVID-19 Era (33 views)
Borbone N, Piccialli I, Falanga AP, Piccialli V, Roviello GN, Oliviero G
International Journal Of Molecular Sciences, 2022 Jun; 23: 4359-4375.
Impact Factor: 5.924
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* River therapy (75 views) (PDF 21 views)
Roviello V, Gilhen-baker M, Roviello GN, Lichtfouse E
Environ Chem Lett (ISSN: 1610-3653linking), 2022 Jun; N/D: 1-6.
Impact Factor: 13.615
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* Exploring the Parallel G-Quadruplex Nucleic Acid World: A Spectroscopic and Computational Investigation on the Binding of the c-myc Oncogene NHE III1 Region by the Phytochemical Polydatin (25 views)
Greco F, Musumeci D, Borbone N, Falanga AP, D , #xerrico S, Terracciano M, Piccialli I, Roviello GN, Oliviero G
Molecules (ISSN: 1420-3049linking), 2022 May 7; 27(9): 2997-3006.
Impact Factor: 4.412
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* Old growth forests and large old trees as critical organisms connecting ecosystems and human health. A review (52 views) (PDF 11 views)
Gilhen-baker M, Roviello V, Beresford-kroeger D, Roviello GN
Environ Chem Lett (ISSN: 1610-3653linking), 2022 May; 20(2): 1529-1538.
Impact Factor: 13.615
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* The Healing Power of Clean Rivers: In Silico Evaluation of the Antipsoriatic Potential of Apiin and Hyperoside Plant Metabolites Contained in River Waters (35 views)
Roviello V, Gilhen-baker M, Vicidomini C, Roviello GN
Int J Environ Res Public Health (ISSN: 1660-4601linking), 2022 Feb 22; 19(5): 2502-2510.
Impact Factor: 3.39
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* Protein Binding of Benzofuran Derivatives: A CD Spectroscopic and In Silico Comparative Study of the Effects of 4-Nitrophenyl Functionalized Benzofurans and Benzodifurans on BSA Protein Structure (55 views)
Scognamiglio PL, Vicidomini C, Fontanella F, De Stefano C, Palumbo R, Roviello GN
Biomolecules (ISSN: 2218-273xlinking), 2022 Feb; 12(2): 262-273.
Impact Factor: 6.064
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* Evaluating In Silico the Potential Health and Environmental Benefits of Houseplant Volatile Organic Compounds for an Emerging 'Indoor Forest Bathing' Approach (35 views)
Roviello V, Scognamiglio PL, Caruso U, Vicidomini C, Roviello GN
Int J Environ Res Public Health (ISSN: 1660-4601linking), 2022 Jan 16; 19(1): 273-273.
Impact Factor: 3.39
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* Anti-Coronavirus Vaccines: Past Investigations on SARS-CoV-1 and MERS-CoV, the Approved Vaccines from BioNTech/Pfizer, Moderna, Oxford/AstraZeneca and others under Development Against SARSCoV- 2 Infection (5 views)
Costanzo M, De Giglio MAR, Roviello GN
Curr Med Chem (ISSN: 0929-8673linking), 2022; 29 (1 ): 4-18.
Impact Factor:
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* Forest-bathing and physical activity as weapons against COVID-19: a review (423 views)
Roviello V, Gilhen-baker M, Vicidomini C, Roviello GN
Environ Chem Lett (ISSN: 1610-3653linking), 2022; 20(1): 131-140.
Impact Factor: 13.615
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* Less COVID-19 deaths in southern and insular Italy explained by forest bathing, Mediterranean environment, and antiviral plant volatile organic compounds (21 views)
Roviello V, Roviello GN
Environ Chem Lett (ISSN: 1610-3653linking), 2022; 20(1): 7-17.
Impact Factor: 13.615
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* River therapy (5 views)
Roviello V, Gilhen-baker M, Roviello GN, Lichtfouse E
Environ Chem Lett (ISSN: 1610-3653linking), 2022; 20 (5 ): 2729-2734.
Impact Factor:
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* Novel insights on nucleopeptide binding: a spectroscopic and in silico investigation on the interaction of a thymine-bearing tetrapeptide with a homoadenine DNA (48 views)
Musumeci D, Ullah S, Ikram A, Roviello GN
Journal Of Molecular Liquids, 2021 Dec; 117975: 14140-14148.
Impact Factor: 6.165
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* Less COVID-19 deaths in southern and insular Italy explained by forest bathing, Mediterranean environment, and antiviral plant volatile organic compounds (34 views)
Roviello V, Roviello GN
Environ Chem Lett (ISSN: 1610-3653linking), 2021 Nov; N/D: 1-11.
Impact Factor: 9.027
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* Probing the Ca2+ Mobilizing Properties on Primary Cortical Neurons of a New Stable cADPR Mimic (18 views)
D'Errico S, Greco F, Falanga AP, Tedeschi V, Piccialli I, Marzano M, Terracciano M, Secondo A, Roviello GN, Oliviero G, Borbone N
Bioorg Chem (ISSN: 0045-2068linking), 2021 Oct 2; 117: 105401-105411.
Impact Factor: 5.275
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* Forest-bathing and physical activity as weapons against COVID-19: a review (15 views)
Roviello V, Gilhen-baker M, Vicidomini C, Roviello GN
Environ Chem Lett (ISSN: 1610-3653linking), 2021 Oct; N/D: 1-10.
Impact Factor: 9.027
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* Evidence of Protein Binding by a Nucleopeptide Based on a Thyminedecorated L-Diaminopropanoic Acid through CD and In Silico Studies (26 views) (PDF 12 views)
Roviello V, Musumeci D, Mokhir A, Roviello GN
Curr Med Chem (ISSN: 0929-8673linking), 2021 Jul; 28(24): 5004-5015.
Impact Factor: 4.53
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* In Silico Investigation on the Interaction of Chiral Phytochemicals from Opuntia ficus-indica with SARS-CoV-2 Mpro (15 views)
Vicidomini C, Roviello V, Roviello GN
Symmetry, 2021 Jul; 13: 1041-1048.
Impact Factor: 2.713
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* From Prebiotic Chemistry to Supramolecular Biomedical Materials: Exploring the Properties of Self-Assembling Nucleobase-Containing Peptides (28 views)
Scognamiglio PL, Platella C, Napolitano E, Musumeci D, Roviello GN
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Jun 10; 26(12): 3558-3558.
Impact Factor: 4.411
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* Spectroscopic and In Silico Studies on the Interaction of Substituted Pyrazolo[1, 2-a]benzo[1, 2, 3, 4]tetrazine-3-one Derivatives with c-Myc G4-DNA (26 views)
Mulliri S, Laaksonen A, Spanu P, Farris R, Farci M, Mingoia F, Roviello GN, Mocci F
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2021 Jun 2; 22(11): 6028-6028.
Impact Factor: 5.923
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* Anti-Coronavirus Vaccines: Past Investigations on SARS-CoV-1 and MERS-CoV, the Approved Vaccines from BioNTech/Pfizer, Moderna, Oxford/AstraZeneca and others under Development Against SARS-CoV-2 Infection (27 views)
Costanzo M, De Giglio MAR, Roviello GN
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021 May 21; DOI:10.2174/09298673: 1-1.
Impact Factor: 4.53
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* Molecular Basis of the Therapeutical Potential of Clove (Syzygium aromaticum L. ) and Clues to Its Anti-COVID-19 Utility (78 views)
Vicidomini C, Roviello V, Roviello GN
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Mar 26; 26(7): 1880-1886.
Impact Factor: 4.411
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* Synthesis and Spectroscopic Investigation of a Hexaaza Lanthanum(III) Macrocycle with a Hybrid-Type G4 DNA Stabilizing Effect (102 views)
Fik-jaskółka MA, Pospieszna-markiewicz I, Roviello GN, Kubicki M, Radecka-paryzek W, Patroniak V
Inorg Chem (ISSN: 0020-1669linking, 1520-510x), 2021 Feb 15; 60(4): 2122-2126.
Impact Factor: 5.165
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* Nucleoside Analogs and Nucleoside Precursors as Drugs in the Fight against SARS-CoV-2 and Other Coronaviruses (109 views)
Borbone N, Piccialli G, Roviello GN, Oliviero G
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Feb 13; 26(4): 986-1002.
Impact Factor: 4.411
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* Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine based compounds on β-amyloid aggregation (145 views)
Marasco D, Vicidomini C, Krupa P, Cioffi F, Pham DQH, Li MS, Florio D, Broersen K, De Pandis MF, Roviello GN
Chem Biol Interact (ISSN: 0009-2797linking), 2021 Jan 25; 334: 109300-109301.
Impact Factor: 5.192
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* Lower COVID-19 mortality in Italian forested areas suggests immunoprotection by Mediterranean plants (179 views)
Roviello V, Roviello GN
Environ Chem Lett (ISSN: 1610-3653linking), 2021 Jan; 19: 699-710.
Impact Factor: 9.027
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* Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes (150 views)
Riccardi C, Capasso D, Coppola A, Platella C, Montesarchio D, Di Gaetano S, Roviello GN, Musumeci D
Pharmaceuticals (ISSN: 1424-8247linking, 1424-8247print), 2020 Sep 30; 13(10): 284-284.
Impact Factor: 4.421
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* Thiophene-benzothiazole dyad ligand and its Ag(I) complex – synthesis, characterization, interactions with DNA and BSA (124 views)
Szymańska M, Insińska-rak M, Dutkiewicz G, Roviello GN, Fik-jaskółka MA, Patroniak V
Journal Of Molecular Liquids, 2020 Sep; 319: 114182-114182.
Impact Factor: 5.065
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* Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex (136 views)
D’errico S, Falanga AP, Capasso D, Di Gaetano S, Marzano M, Terracciano M, Roviello GN, Piccialli G, Oliviero G, Borbone N
Pharmaceutics (ISSN: 1999-4923linking), 2020 Jul 4; 12(7): 627-627.
Impact Factor: 4.421
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* Synthesis and nucleic acid binding evaluation of a thyminyl L-diaminobutanoic acid-based nucleopeptide (151 views)
Musumeci D, Mokhir A, Roviello GN
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2020 Jul; 100: 103862-103870.
Impact Factor: 4.831
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* Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach (205 views)
Platella C, Raucci U, Rega N, D’atri S, Levati L, Roviello GN, Fuggetta MP, Musumeci D, Montesarchio D
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2020 May 15; 151: 1163-1172.
Impact Factor: 5.162
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* Biological macromolecule binding and anticancer activity of synthetic alkyne-containing L-phenylalanine derivatives (143 views)
Fik-jaskółkaa MA, Mkrtchyand AF, Saghyand AS, Palumbo R, Belter A, Hayriyand LA, Simonyane H, Roviello V, Roviello GN
Amino Acids (ISSN: 0939-4451linking, 1438-2199electronic), 2020 May; 52(5): 755-769.
Impact Factor: 3.063
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* SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavirus (317 views)
Costanzo M, De Giglio MAR, Roviello GN
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2020 Apr 16; 27(27): 4536-4541.
Impact Factor: 4.184
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* Intestinimonas-like bacteria are important butyrate producers that 1 utilize Nε-fructosyllysine and lysine in formula-fed infants and adults (122 views)
Bui N, Troise AD, Nijsse B, Roviello GN, Fogliano V, Devos W
Journal Of Functional Foods, 2020 Apr; 70: 103974-103980.
Impact Factor: 3.701
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* Spectroscopic and SEM evidences for G4-DNA binding by a synthetic alkyne-containing amino acid with anticancer activity (210 views) (PDF 75 views)
Fik-jaskółka MA, Mkrtchyan AF, Saghyan AS, Palumbo R, Belter A, Hayriyan LA, Simonyan H, Roviello V, Roviello GN
Spectrochim Acta A (ISSN: 1386-1425linking), 2020 Mar 15; 229: 117884-117884.
Impact Factor: 3.232
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* Structural and Functional Characterization of New SsoPox Variant Points to the Dimer Interface as a Driver for the Increase in Promiscuous Paraoxonase Activity (199 views) (PDF 58 views)
Suzumoto Y, Dim O, Roviello GN, Worek F, Sussman JL, Manco G
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2020 Mar 1; 21(5): 1683-1707.
Impact Factor: 4.556
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* Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)- complexes with an L-alanyl-based ligand (261 views)
Riccardi C, Capasso D, Rozza GM, Platella C, Montesarchio D, Di Gaetano S, Marzo T, Pratesi A, Messori L, Roviello GN, Musumeci D
J Chem Res (ISSN: 0162-0134linking, 0162-0134print), 2020 Feb; 203: 110868-110868.
Impact Factor: 3.224
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* Evaluation of an Analogue of the Marine ε-PLL Peptide as a Ligand of G-quadruplex DNA Structures (164 views) (PDF 61 views)
Marzano M, Falanga AP, Marasco D, Borbone N, D , #errico S, Piccialli G, Roviello GN, Oliviero G
Mar Drugs (ISSN: 1660-3397linking), 2020 Jan 11; 18(1): 49-60.
Impact Factor: 4.073
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* Synthesis, self-assembly-behavior and biomolecular recognition properties of thyminyl dipeptides (444 views) (PDF 78 views)
Roviello GN, Oliviero G, Di Napoli A, Borbone N, Piccialli G
Arabian Journal Of Chemistry, 2020; 13: 1966-1974.
Impact Factor: 4.762
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* Recent Advances in Nuclear Imaging of Receptor Expression to Guide Targeted Therapies in Breast Cancer (219 views) (PDF 90 views)
Salvatore B, Caprio MG, Hill BS, Sarnella A, Roviello GN, Zannetti A
Cancers (ISSN: 2072-6694linking), 2019 Oct 22; 11(10): N/D-N/D.
Impact Factor: 6.162
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* New artificial biomimetic enzyme analogues based on iron(II/III) Schiff Base complexes: an effect of (benz)imidazole organic moieties on phenoxazinone synthase and DNA recognition (225 views)
Bocian A, Szymańska M, Brykczyńska D, Kubicki M, Wałęsa-chorab M, Roviello GN, Fik-jaskółka MA, Gorczyński A, Patroniak V
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2019 Aug 31; 24(17): 3173-3173.
Impact Factor: 3.06
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* Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound (570 views)
Vicidomini C, Cioffi F, Broersen K, Roviello V, Riccardi C, Montesarchio D, Capasso D, Gaetano SD, Musumeci D, Roviello GN
Future Med Chem (ISSN: 1756-8919linking, 1756-8927electronic), 2019 Feb 25; 11: 285-302.
Impact Factor: 3.617
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* New G-quadruplex-forming oligodeoxynucleotides incorporating a bifunctional Double-Ended Linker (DEL): effects of DEL size and ODNs orientation on the topology, stability and molecularity of DEL-G-quadruplexes (279 views)
Marzano M, Falanga AP, D'Errico S, Pinto B, Roviello GN, Piccialli G, Oliviero G, Borbone N
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2019 Feb 12; 24(3): 654-654.
Impact Factor: 3.06
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* Evaluating the biological properties of synthetic 4-nitrophenyl functionalized benzofuran derivatives with telomeric DNA binding and antiproliferative activities (411 views)
Carella A, Roviello V, Iannitti R, Palumbo R, La Manna S, Marasco D, Trifuoggi M, Diana R, Roviello GN
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Jan; 121: 77-88.
Impact Factor: 4.784
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* Novel insights into nucleoamino acids: biomolecular recognition and aggregation studies of a thymine-conjugated L-phenyl alanine (379 views)
Roviello GN
Amino Acids (ISSN: 1438-2199electronic, 0939-4451linking), 2018 May 15; DOI10.1007/s00726-01: 933-941.
Impact Factor: 3.173
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* DNA- and RNA-binding ability of oligoDapT, a nucleobase-decorated peptide, for biomedical applications (1959 views)
Musumeci D, Roviello V, Roviello GN
Int J Nanomed (ISSN: 1176-9114linking, 1178-2013electronic), 2018 May 1; 2018:13: 2613-2629.
Impact Factor: 4.3
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* A COMPUTER MODELING STUDY OF BINDING PROPERTIES OF CHIRAL NUCLEOPEPTIDE FOR BIOMEDICAL APPLICATIONS (430 views)
Pirtskhalava M, Egoyan A, Mirtskhulava M, Roviello GN
Georgian Med News (ISSN: 1512-0112print, 1512-0112linking), 2017 Dec; (273): 1123-1128.
Impact Factor: 0
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* Antitumour activity of resveratrol on human melanoma cells: a possible mechanism related to its interaction with malignant cell telomerase (290 views)
Platella C, Guida S, Bonmassar L, Aquino A, Bonmassar E, Ravagnan G, Montesarchio D, Roviello GN, Musumeci D, Fuggetta MP
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2017 Aug 02; 1861(11PtA): 2843-2851.
Impact Factor: 4.28
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* Lac-L-TTA, a novel lactose-based amino acid-sugar conjugate for anti-metastatic applications (338 views)
Roviello GN, Iannitti R, Palumbo R, Simonyan H, Vicidomini C, Roviello V
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2017 May 06; 49(8): 1347-1353.
Impact Factor: 2.906
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* G-quadruplex-based aptamers against protein targets in therapy and diagnostics (307 views)
Platella C, Riccardi C, Montesarchio D, Roviello GN, Musumeci D
Bba-Gen Subjects (ISSN: 0304-4165, 0006-3002, 1872-8006electronic), 2017 May; 1861(5PtB): 1429-1447.
Impact Factor: 3.679
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* Synthesis and biological evaluation of a novel Amadori compound (407 views)
Roviello GN, Iannitti R, Roviello V, Palumbo R, Simonyan H, Vicidomini C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2017 Feb; 49(2): 327-335.
Impact Factor: 2.906
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* Benzodifuran derivatives as potential antiproliferative agents: possible correlation between the bioactivity and their aggregation properties (477 views)
Musumeci D, Roviello GN, Rigione G, Capasso D, Di Gaetano S, Riccardi C, Roviello V, Montesarchio D
Chempluschem, 2017; 82: 251-260.
Impact Factor: 2.8
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* Nucleic acid binding and other biomedical properties of artificial oligolysines (283 views)
Roviello GN, Vicidomini C, Costanzo V, Roviello V
International Journal Of Nanomedicine, 2016 Nov; 11: 5897-5904.
Impact Factor: 4.32
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* Synthetic approaches to nucleopeptides containing all the four nucleobases, and nucleic acid-binding studies on a mixed-sequence nucleo-oligolysine (435 views)
Roviello GN, Musumeci D
Rsc Adv (ISSN: 2046-2069), 2016 Jun; 6: 63578-63585.
Impact Factor: 3.108
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* Synthesis and Enantiomeric Separation of a Novel Spiroketal derivative: A Potent Human Telomerase Inhibitor with High In Vitro Anticancer Activity (363 views)
Fuggetta MP, De Mico A, Cottarelli A, Morelli F, Zonfrillo M, Ulgheri F, Peluso P, Mannu A, Deligia F, Marchetti M, Roviello GN, Romero AR, Dömling A, Spanu P
Journal Of Medicinal Chemistry, 2016 Mar; 59: 9140-9149.
Impact Factor: 5.589
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* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (402 views)
Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
Rsc Adv (ISSN: 2046-2069), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
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* Solid phase synthesis of TyrT, a thymine-tyrosine conjugate with poly(A) RNA-binding ability (505 views)
Roviello GN, Roviello V, Autiero I, Saviano M
Rsc Adv (ISSN: 2046-2069), 2016; 6(33): 27607-27613.
Impact Factor: 3.108
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* In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET (736 views) (PDF 263 views)
Vicidomini C, Panico M, Greco A, Gargiulo S, Coda ARD, Zannetti A, Gramanzini M, Roviello GN, Quarantelli M, Alfano B, Tavitian B, Dolle F, Salvatore M, Brunetti A, Pappata S
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 2015 Mar; 42(3): 309-316.
Impact Factor: 2.429
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* Solid phase synthesis of a novel folate-conjugated 5-aminolevulinic acid methyl ester based photosensitizer for selective photodynamic therapy (422 views)
Guaragna A, Roviello GN, D'Errico S, Paolella C, Palumbo G, D'Alonzo D
Tetrahedron Lett (ISSN: 0040-4039), 2015 Feb 4; 56(6): 775-778.
Impact Factor: 2.347
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* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (1375 views)
Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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* Cationic peptides as RNA compaction agents: A study on the polyA compaction activity of a linear alpha, epsilon-oligo-l-lysine (480 views)
Roviello GN, Musumeci D, Roviello V
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2015; 485(1-2): 244-248.
Impact Factor: 3.994
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* Natural and artificial binders of polyriboadenylic acid and their effect on RNA structure (380 views)
Roviello GN, Musumeci D, Roviello V, Pirtskhalava M, Egoyan A, Mirtskhulava M
Beilstein J Nanotech (ISSN: 2190-4286), 2015; 6(1): 1338-1347.
Impact Factor: 2.778
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* Thiophenyl-substituted triazolyl-thione L-alanine: asymmetric synthesis, aggregation and biological properties (489 views)
Saghyan AS, Simonyan HM, Petrosyan SG, Geolchanyan AV, Roviello GN, Musumeci D, Roviello V
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014 Oct; 46(10): 2325-2332.
Impact Factor: 3.293
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* Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo (375 views)
Romano M, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2014 May 6; 22(5): 719-730.
Impact Factor: 5.618
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* An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies (559 views)
Musumeci D, Roviello GN, Montesarchio D
Pharmacol Ther (ISSN: 0163-7258, 0163-7258linking), 2014 Mar; 141(3): 347-357.
Impact Factor: 9.723
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* Binding ability of a thymine-functionalized oligolysine towards nucleic acids (347 views)
Roviello GN, Musumeci D, D'Alessandro C, Pedone C
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2014 Feb 1; 22(3): 997-1002.
Impact Factor: 2.793
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* Synthesis and supramolecular assembly of 1, 3-bis(1 '-uracilyl)-2-propanone (404 views)
Roviello GN, Roviello GN, Musumeci D, Capasso D, Di Gaetano S, Costanzo M, Pedone C
Rsc Adv (ISSN: 2046-2069), 2014; 4(54): 28691-28698.
Impact Factor: 3.84
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* Synthesis of a thymine-functionalized nucleoamino acid for the solid phase assembly of cationic nucleopeptides (486 views)
Roviello GN, Musumeci D, D'Alessandro C, Pedone C
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2013 Oct; 45(4): 779-784.
Impact Factor: 3.653
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* Dipentyl 2, 6-diaminobenzo[1, 2-b: 4, 5-b']difuran-3, 7-dicarboxylate (275 views)
Roviello G, Borbone F, Carella A, Roviello GN, Tuzi A
Acta Crystallographica Section E Structure Reports Online (ISSN: 1600-5368, 1600-5368electronic), 2013 Sep 12; 69(Pt10): o1526-o1526.
Impact Factor: 2.069
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* Synthesis of a novel benzodifuran derivative and its molecular recognition of poly rA RNA (365 views)
Roviello GN, Roviello V, Musumeci D, Pedone C
Biol Chem Biological Chemistry (ISSN: 1437-4315, 1431-6730), 2013 Sep; 394(9): 1235-1239.
Impact Factor: 2.689
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* Hairpin ODN-based ligands as potential inhibitors of HMGB1 cytokine activity (436 views)
Musumeci D, Roviello GN, Montesarchio D, Sapio R, Valente M, Anr V, Bucci EM
Rsc Adv (ISSN: 2046-2069), 2013; 3(30): 12176-12184.
Impact Factor: 3.708
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* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (444 views)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
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* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (439 views)
Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
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* Synthesis and aggregation properties of a novel enzymatically resistant nucleoamino acid (423 views)
Roviello GN, Mottola A, Musumeci D, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Oct; 43(4): 1465-1470.
Impact Factor: 3.914
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* G-quadruplex-forming oligonucleotide conjugated to magnetic nanoparticles: Synthesis, characterization, and enzymatic stability assays (816 views)
Musumeci D, Oliviero G, Roviello GN, Bucci EM, Piccialli G
Bioconjug Chem (ISSN: 1043-1802, 1520-4812, 1520-4812electronic), 2012 Mar 21; 23(3): 382-391.
Impact Factor: 4.58
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* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (531 views)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
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* Nucleobase-containing peptides: a spectroscopic study of their properties and nucleic acids recognition ability (394 views)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Eur Biophys J (ISSN: 0175-7571, 1432-1017, 0175-7571linking), 2011 Sep; 40: N/D-N/D.
Impact Factor: 2.139
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* DNA-based strategies for blocking HMGB1 cytokine activity: Design, synthesis and preliminary in vitro/in vivo assays of DNA and DNA-like duplexes (481 views)
Musumeci D, Bucci EM, Roviello GN, Sapio R, Valente M, Moccia M, Bianchi ME, Pedone C
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1742-1752.
Impact Factor: 3.534
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* Synthesis, biological evaluation and supramolecular assembly of novel analogues of peptidyl nucleosides (1543 views)
Roviello GN, Ricci A, Bucci EM, Pedone C
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 May; 7(5): 1773-1778.
Impact Factor: 3.534
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* RNA-binding and viral reverse transcriptase inhibitory activity of a novel cationic diamino acid-based peptide (610 views)
Roviello GN, Di Gaetano S, Capasso D, Franco S, Crescenzo C, Bucci EM, Pedone C
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2011 Apr 14; 54(7): 2095-2101.
Impact Factor: 5.248
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* Evidences for supramolecular organization of nucleopeptides: Synthesis, spectroscopic and biological studies of a novel dithymine l-serine tetrapeptide (578 views)
Roviello GN, Musumeci D, Bucci EM, Pedone C
Mol Biosyst (ISSN: 1742-206x, 1742-2051, 1742-2051electronic), 2011 Apr; 7(4): 1073-1080.
Impact Factor: 3.534
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* Synthesis of a l-lysine-based alternate alpha, epsilon-peptide: A novel linear polycation with nucleic acids-binding ability (465 views)
Moccia M, Roviello GN, Bucci EM, Pedone C, Saviano M
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2010 Sep 15; 397(1-2): 179-183.
Impact Factor: 3.607
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* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (464 views)
Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
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* Nucleobase-containing peptides: An overview of their characteristic features and applications (753 views)
Roviello GN, Benedetti E, Pedone C, Bucci EM
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jun; 39(1): 45-57.
Impact Factor: 4.106
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* Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (804 views)
Roviello GN, Gröschel S, Pedone C, Diederichsen U
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2010 May; 38(5): 1301-1309.
Impact Factor: 4.106
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* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (443 views)
Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
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* Alternate dab-aegPNAs: synthesis, nucleic acid binding studies and biological activity (526 views)
Roviello GN, Musumeci D, De Cristofaro A, Capasso D, Di Gaetano S, Bucci EM, Pedone C
Mol Biosyst (ISSN: 1742-2051, 1742-206x, 1742-2051electronic), 2010 Jan; 6(1): 199-205.
Impact Factor: 3.825
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* Synthesis, Characterization And Hybridization Studies Of An Alternate Nucleo-Epsilon/Gamma-Peptide: Complexes Formation With Natural Nucleic Acids (494 views)
Roviello GN, Musumeci D, Pedone C, Bucci EM
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Jan; 38(1): 103-111.
Impact Factor: 4.106
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* Erratum: Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras (Amino Acids DOI: 10. 1007/s00726-009-0324-x) (312 views)
Roviello GN, Gröschel S, Pedone C, Diederichsen U
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010; 38(5): 1311-1312.
Impact Factor: 4.106
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* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (928 views)
Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
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* Synthesis, structure and reactivity of amino-benzodifurane derivatives (430 views)
Caruso U, Panunzi B, Roviello GN, Roviello GN, Tingoli M, Tuzi A
Comptes Rendus Chimie (ISSN: 1631-0748), 2009 May; 12(5): 622-634.
Impact Factor: 1.58
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* Evidences Of Complex Formation Between Daba-Based Nucleo-Gamma-Peptides With Alternate Configuration Backbone (431 views)
Roviello GN, Musumeci D, Moccia M, Castiglione M, Cesarani A, Bucci EM, Saviano M, Pedone C, Benedetti E
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 147-154.
Impact Factor: 1.807
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* Solid Phase Synthesis And Rna-Binding Studies Of A Serum-Resistant Nucleo-Epsilon-Peptide (435 views)
Roviello GN, Musumeci D, Castiglione M, Bucci EM, Pedone C, Benedetti E
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 155-160.
Impact Factor: 1.807
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* Evidences for complex formation between l-dabPNA and aegPNA (304 views)
Roviello GN, Musumeci D, Bucci EM, Castiglione M, Cesarani A, Pedone C, Piccialli G
Bioorg Med Chem Lett (ISSN: 0960-894x, 1464-3405, 1464-3405electronic), 2008 Sep 1; 18(17): 4757-4760.
Impact Factor: 2.531
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* Bent oligonucleotide duplexes as HMGB1 inhibitors: A comparative study (350 views)
Musumeci D, Roviello GN, Moccia M, Pedone C, Bucci EM, Sapio R, Valente M, Fumero S
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1447-1450.
Impact Factor: 0.723
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* Dabpna: Design, Synthesis And Nucleic Acids Binding Studies (430 views)
Roviello GN, Musumeci D, Moccia M, Castiglione M, Sapio R, Valente M, Bucci EM, Perretta G, Pedone C
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(10-12): 1307-1310.
Impact Factor: 0.723
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* ODN-based drugs for targeting of extracellular proteins (284 views)
Bucci EM, Valente M, Musumeci D, Sapio R, Anrò V, Roviello GN, Moccia M
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1047-1050.
Impact Factor: 0.723
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* Thermodynamic studies on PNA and PNA/DNA dendrimer formation (242 views)
Moccia M, Musumeci D, Valente M, Roviello GN, Sapio R, Pedone C, Bucci EM
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1173-1176.
Impact Factor: 0.723
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* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (493 views)
Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
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116 Records (113 excluding Abstracts).
Total impact factor: 507.467 (499.58 excluding Abstracts).
Total 5 year impact factor: 419.775 (395.415 excluding Abstracts).

Last modified by Giovanni Nicola Roviello on Wednesday 10 May 2023, 15:32:57
7940 views. Last view on Thursday 08 June 2023, 13:22:53