* High-Resolution Conformational Analysis of RGDechi-Derived Peptides Based on a Combination of NMR Spectroscopy and MD Simulations (27 views)
Acconcia C, Paladino A, Valle MD, Farina B, Del Gatto A, Gaetano SD, Capasso D, Gentile MT, Malgieri G, Isernia C, Saviano M, Fattorusso R, Zaccaro L, Russo L
Int J Mol Sci (ISSN: 1422-0067linking), 2022 Sep 20; 23 (19 ): N/D-N/D.
Impact Factor:
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* An Overview of Peptide-Based Molecules as Potential Drug Candidates for Multiple Sclerosis (100 views)
Del Gatto A, Saviano M, Zaccaro L
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2021 Aug 28; 26(17): N/D-N/D.
Impact Factor: 4.411
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* A novel approach for studying receptor-ligand interactions on living cells surface by using NUS/T1ρ-NMR methodologies combined with computational techniques: The RGDechi15D-α(v)β(5) integrin complex (137 views)
Farina B, Andrea C, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Paladino A, Acconcia C, Teresa Gentile M, Saviano M, Fattorusso R, Zaccaro L, Russo L
Comput Struct Biotechnol J (ISSN: 2001-0370linking), 2021 May 29; 19: 3303-3318.
Impact Factor: 7.271
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* Selective Targeting of αvβ5 Integrin in HepG2 Cell Line by RGDechi15D Peptide (163 views)
Capasso D, Del Gatto A, Comegna D, Russo L, Fattorusso R, Saviano M, Di Gaetano S, Zaccaro L
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2020 Sep 19; 25(18): N/D-N/D.
Impact Factor: 3.267
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* Gold-Speckled SPION@SiO(2) Nanoparticles Decorated with Thiocarbohydrates for ASGPR1 Targeting: Towards HCC Dual Mode Imaging Potential Applications (131 views)
Siciliano G, Corricelli M, Iacobazzi RM, Canepa F, Comegna D, Fanizza E, Del Gatto A, Saviano M, Laquintana V, Comparelli R, Mascolo G, Murgolo S, Striccoli M, Agostiano A, Denora N, Zaccaro L, Curri ML, Depalo N
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2020 Aug 26; 26(48): 11048-11059.
Impact Factor: 4.857
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* A Multi-Targeting Approach to Fight SARS-CoV-2 Attachment (701 views) (PDF 187 views)
Pirone L, Del Gatto A, Di Gaetano S, Saviano M, Capasso D, Zaccaro L, Pedone E
Front Mol Biosci (ISSN: 2296-889xlinking), 2020 Aug 3; 7: 186-186.
Impact Factor: 4.188
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* On-Bead Peptoid Dimerization Induced by Incorporation of Glycosylated Bridging Units in Submonomer Solid-Phase Approach to Glycopeptoids (265 views)
Comegna D, Del Gatto A, Saviano M, Zaccaro L
Org Lett (ISSN: 1523-7052linking, 1523-7052electronic, 1523-7060), 2019 Jun 21; 21(12): 4454-4458.
Impact Factor: 5.128
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* Conformational studies of RGDechi peptide by natural-abundance NMR spectroscopy (298 views)
Farina B, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Isernia C, Saviano M, Fattorusso R, Zaccaro L, Russo L
J Pept Sci (ISSN: 1075-2617linking, 1099-1387electronic), 2019 May; 25(5): e3166-e3166.
Impact Factor: 1.807
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* Therapeutic Potential of a Novel alphavbeta(3) Antagonist to Hamper the Aggressiveness of Mesenchymal Triple Negative Breast Cancer Sub-Type (422 views) (PDF 118 views)
Hill BS, Sarnella A, Capasso D, Comegna D, Del Gatto A, Gramanzini M, Albanese S, Saviano M, Zaccaro L, Zannetti A
Cancers (ISSN: 2072-6694linking), 2019 Jan 24; 11(2): 139-139.
Impact Factor: 6.126
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* [(99m)Tc][Tc(N)PNP43]-Labeled RGD Peptides As New Probes for a Selective Detection of alphavbeta3 Integrin: Synthesis, Structure-Activity and Pharmacokinetic Studies (473 views)
Bolzati C, Salvarese N, Carpanese D, Seraglia R, Melendez-alafort L, Rosato A, Capasso D, Saviano M, Del Gatto A, Comegna D, Zaccaro L
J Med Chem (ISSN: 0022-2623linking, 0022-2623print, 1520-4804electronic), 2018 Nov 8; 61(21): 9596-9610.
Impact Factor: 6.253
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* A selective αvβ5 integrin antagonist hidden into the anophelin family protein cE5 from the malaria vector Anopheles gambiae (350 views)
Di Gaetano S, Del Gatto A, Pirone L, Comegna D, Zaccaro L, Saviano M, Arcà B, Capasso D, Pedone E
Peptide Science, 2018; N/D: N/D-N/D.
Impact Factor: 2.081
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* Deciphering RGDechi peptide‐α5β1 integrin interaction mode in isolated cell membranes (334 views)
Russo L, Farina B, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Liguoro D, Malgieri G, Saviano M, Fattorusso R, Zaccaro L
Peptide Science, 2018; N/D: N/D-N/D.
Impact Factor: 2.081
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* Chemical Modification for Proteolytic Stabilization of the Selective alphavbeta3 Integrin RGDechi Peptide: in Vitro and in Vivo Activities on Malignant Melanoma Cells (1015 views) (PDF 223 views)
Comegna D, Zannetti A, Del Gatto A, De Paola I, Russo L, Di Gaetano S, Liguoro A, Capasso D, Saviano M, Zaccaro L
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2017 Dec 14; 60(23): 9874-9884.
Impact Factor: 6.253
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* NIR Emitting Nanoprobes Based on Cyclic RGD Motif Conjugated PbS Quantum Dots for Integrin-Targeted Optical Bioimaging (497 views) (PDF 199 views)
Depalo N, Corricelli M, De Paola I, Valente G, Iacobazzi RM, Altamura E, Debellis D, Comegna D, Fanizza E, Denora N, Laquintana V, Mavelli F, Striccoli M, Saviano M, Agostiano A, Del Gatto A, Zaccaro L, Curri ML
Acs Appl Mater Inter (ISSN: 1944-8244), 2017 Dec 13; 9(49): 43113-43126.
Impact Factor: 8.097
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* Insights into the anticancer properties of the first antimicrobial peptide from Archaea (466 views)
Gaglione R, Pirone L, Farina B, Fusco S, Smaldone G, Aulitto M, Dell'Olmo E, Roscetto E, Del Gatto A, Fattorusso R, Notomista E, Zaccaro L, Arciello A, Pedone E, Contursi P
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 0304-4165linking), 2017 Jun 15; 1861(9): 2155-2164.
Impact Factor: 4.28
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* A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 beta-like: from in silico identification to experimental evidence (439 views)
Bosso A, Pirone L, Gaglione R, Pane K, Del Gatto A, Zaccaro L, Di Gaetano S, Diana D, Fattorusso R, Pedone E, Cafaro V, Haagsman HP, Van Dijk A, Scheenstra MR, Zanfardino A, Crescenzi O, Arciello A, Varcamonti M, Veldhuizen EJA, Di Donato A, Notomista E, Pizzo E
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2017 Apr 25; N/D: N/D-N/D.
Impact Factor: 4.28
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* Silver nanoparticles functionalized with a fluorescent cyclic RGD peptide: a versatile integrin targeting platform for cells and bacteria (368 views) (PDF 181 views)
Di Pietro P, Zaccaro L, Comegna D, Del Gatto A, Saviano M, Snyders R, Cossement D, Satriano C, Rizzarelli E
The Royal Society Of Chemistry, 2016 Jan 01; 6: N/D-N/D.
Impact Factor: 3.564
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* Integrin-targeting with peptide-bioconjugated semiconductor-magnetic nanocrystalline heterostructures (461 views)
Valente G, Depalo N, De Paola I, Iacobazzi RM, Denora N, Laquintana V, Comparelli R, Altamura E, Latronico T, Altomare M, Fanizza E, Striccoli M, Agostiano A, Saviano M, Del Gatto A, Zaccaro L, Curri ML
Nano Res (ISSN: 1998-0124), 2016; 9(3): 644-662.
Impact Factor: 7.354
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* Straightforward entry to s-glycosylated fmoc-amino acids and their application to solid phase synthesis of glycopeptides and glycopeptidomimetics (668 views)
Comegna D, de Paola I, Saviano M, Del Gatto A, Zaccaro L
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2015; 17(3): 640-643.
Impact Factor: 6.732
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* Rgdechi-Hcit: Alpha V Beta 3 Selective Pro-Apoptotic Peptide As Potential Carrier For Drug Delivery Into Melanoma Metastatic Cells (600 views)
Capasso D, De Paola I, Liguoro A, Del Gatto A, Di Gaetano S, Guarnieri D, Saviano M, Zaccaro L
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2014 Sep 23; 9(9): e106441-e106441.
Impact Factor: 3.234
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* Selective alpha v beta 3 receptor peptide antagonist for therapeutic and diagnostic applications (1225 views)
Del Gatto A, Zaccaro L, Pedone C, Saviano M
Patents Official Gazette Of The United States Patent And Trademark Office (ISSN: 0098-1133), 2013 Oct 1; N/D: N/D-N/D.
Impact Factor: 0
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* Structural Zn(II) Implies a Switch from Fully Cooperative to Partly Downhill Folding in Highly Homologous Proteins (464 views)
Palmieri M, Malgieri G, Russo L, Baglivo I, Esposito S, Netti F, Del Gatto A, De Paola I, Zaccaro L, Pedone PV, Isernia C, Milardi D, Fattorusso R
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2013 Apr 2; 135(13): 5220-5228.
Impact Factor: 11.444
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* In vitro activity of the alphavbeta3 integrin antagonist RGDechi-hCit on malignant melanoma cells (634 views)
Pisano M, De Paola I, Nieddu V, Sassu I, Cossu S, Galleri G, Del Gatto A, Budroni M, Cossu A, Saviano M, Palmieri G, Zaccaro L, Rozzo C
Anticancer Res (ISSN: 0250-7005, 0250-0700, 1791-7530electronic), 2013 Mar; 33(3): 871-879.
Impact Factor: 1.045
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* Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting (722 views)
Scarí G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, Saviano M, Leone M, Del Gatto A, Pedone C, Zaccaro L
Bioconjug Chem (ISSN: 1520-4812, 1043-1802, 1520-4812electronic), 2012 Mar 21; 23(3): 340-349.
Impact Factor: 4.58
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* Structure-based design of a potent artificial transactivation domain based on p53 (538 views)
Langlois C, Del Gatto A, Arseneault G, Lafrance-vanasse J, De Simone M, Morse T, De Paola I, Lussier-price M, Legault P, Pedone C, Zaccaro L, Omichinski JG
J Am Chem Soc (ISSN: 1520-5126, 0002-2786, 0002-7863), 2012 Jan 25; 134(3): 1715-1723.
Impact Factor: 5.65
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* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (504 views)
Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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* Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo (698 views)
Basile A, Del Gatto A, Diana D, Di Stasi R, Falco A, Festa M, Rosati A, Barbieri A, Franco R, Arra C, Pedone C, Fattorusso R, Turco MC, D'Andrea LD
J Med Chem (ISSN: 1520-4804, 0022-2623, 0022-2623print), 2011 Mar 10; 54(5): 1391-1400.
Impact Factor: 5.248
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* Investigation of the Best Conditions to Obtain c(RGDfK) Peptide on Solid Phase (603 views)
Saviano M, Del Gatto A, De Simone M, De Paola I, Saviano M, Zaccaro L
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2011 Mar; 17(1): 39-45.
Impact Factor: 0.986
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* Evaluation of the anti-angiogenic properties of the new selective alphaVbeta3 integrin antagonist RGDechiHCit (587 views)
Santulli G, Basilicata MF, De Simone M, Del Giudice C, Anastasio A, Sorriento D, Saviano M, Del Gatto A, Trimarco B, Pedone C, Zaccaro L, Iaccarino G
J Transl Med (ISSN: 1479-5876electronic, 1479-5876linking), 2011 Jan 13; 9: 7-7.
Impact Factor: 3.474
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* AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress (512 views)
Perrino C, Feliciello A, Schiattarella GG, Esposito G, Guerriero R, Zaccaro L, Del Gatto A, Saviano M, Garbi C, Carangi R, Di Lorenzo E, Donato G, Indolfi C, Avvedimento VE, Chiariello M
Cardiovascular Research (ISSN: 0008-6363), 2010 Oct; 88(1): 101-110.
Impact Factor: 6.051
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* Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5) (545 views)
Zannetti A, Del Vecchio S, Iommelli F, Del Gatto A,  De Luca S, Zaccaro L, Papaccioli A, Sommella J, Panico M, Speranza A, Grieco P, Novellino E, Saviano M, Pedone C, Salvatore M
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2009 Sep 15; 15(16): 5224-5233.
Impact Factor: 6.747
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* Imaging of αvβ3 expression by a bifunctional chimeric RGD peptide not cross-reacting with α vβ5 (1046 views)
Zannetti A, Del Vecchio S, Iommelli F, Del Gatto A, De Luca S, Zaccaro L, Papaccioli A, Sommella J, Panico M, Speranza A, Grieco P, Novellino E, Saviano M, Pedone C, Salvatore M
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2009 Sep 15; 15(16): 5224-5233.
Impact Factor: 6.747
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* MicroPET/CT of mice bearing alpha(v)beta(3)-expressing tumors by a 18F-labeled bifunctional chimeric RGD peptide (463 views)
Zannetti A, Iommelli F, Panico M, Del Gatto A, Zaccaro L, Saviano M, Pedone C, Salvatore M, Del Vecchio S
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Sep; 36: N/D-N/D.
Impact Factor: 4.531
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* New high yield HPLC purification with ethanol of 18F-RGDEchi and directly injection in mice (555 views)
Panico MM, Lang L, Greco A, Greco A, Gargiulo S, Larobina M, Del Vecchio S, Zannetti A, Zaccaro L, Zaccaro L, Del Gatto A, Saviano M, Alfano B, Salvatore M
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Sep; 36: N/D-N/D.
Impact Factor: 4.531
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* Peptides targeting angiogenesis related growth factor receptors (14800 views)
D'Andrea LD, Del Gatto A, De Rosa L, Romanelli A, Pedone C
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1873-4286, 1381-6128), 2009 Jul; 15(21): 2414-2429.
Impact Factor: 4.414
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* Peptides for tumour therapy and diagnosis: current status and future directions (1584 views)
Zaccaro L, Del Gatto A, Pedone C, Saviano M
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2009 Mar; 16(7): 780-795.
Impact Factor: 4.708
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* A new and selective radiolabeled alpha(V)beta(3) peptide antagonist as tracer in tumor diagnosis (543 views)
De Luca S, Del Gatto A, Ruvo M, Panico M, Zannetti A, Del Vecchio S, Salvatore M, Pedone C, Saviano M, Zaccaro L
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print), 2009; 611: 439-440.
Impact Factor: 2.02
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* An Improved Radiolabeling Synthesis of RGDECHI with 18F-Fluoride (561 views)
Panico M, Lang L, Del Vecchio S, Nardelli A, Castaldi E, Zaccaro L, Del Gatto A, Saviano M, Zannetti A, Larobina M, Gargiulo S, Pedone C, Salvatore M
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Oct; 35: N/D-N/D.
Impact Factor: 4.532
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* Development of new molecules that compete with p53 for Binding to TFIIH (435 views)
Zaccaro L, Del Gatto A, Saviano M, Langella E, Langlois C, Di Lello P, Baffreau J, Mas C, Legault P, Omichinski JG, Pedone C
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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* In vivo imaging of alpha(v) beta(3) integrin expression with a radiolabeled chimeric RGD peptide (481 views)
Del Vecchio S, Zannetti A, Panico M, Speranza A, Iommelli F, Papaccioli A, Sommella J, Lettieri A, Saviano M, Zaccaro L, Del Gatto A, Lang L, Pedone C, Salvatore M
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Oct; 34: N/D-N/D.
Impact Factor: 4.101
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* A new and selective radiolabeled alpha(v)beta 3 peptide antagonist as tracer in tumor diagnosis (445 views)
Zaccaro L, Del Gatto A,  De Luca S, Ruvo M, Zannetti A, Del Vecchio S, Salvatore M, Pedone C, Saviano M
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(4): N/D-N/D.
Impact Factor: 2.389
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* Integrin Receptor Family: Promising Target For Therapeutic And Diagnostic Applications (394 views)
Zaccaro L, Del Gatto A, Pedone C, Saviano M
Current Topics In Biochemical Research (ISSN: 0972-4583), 2007; 9(2): 45-56.
Impact Factor: 0
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* Novel And Selective Alpha (v) Beta3 Receptor Peptide Antagonist: Design, Synthesis, And Biological Behavior (904 views)
Del Gatto A, Zaccaro L, Grieco P, Novellino E, Zannetti A, Del Vecchio S, Iommelli F, Salvatore M, Pedone C, Saviano M
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Jun 1; 49(11): 3416-3420.
Impact Factor: 5.115
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* Peptide-based molecules in angiogenesis (954 views)
D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285, 1747-0277linking), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
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* Engineering Peptides In Angiogenesis (484 views)
Del Gatto A, D'Andrea LD, Zaccaro L, Saviano M, Pedone C, Benedetti E
Biopolymers, 2006; 0: 215-216.
Impact Factor: 2.288
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* Novel and selective alpha v beta 3 receptor peptide antagonist: Design, synthesis and biological behaviour (480 views)
Del Gatto A, Zaccaro L, Zannetti A, Del Vecchio S, Benedetti E, Salvatore M, Pedone C, Saviano M
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006; 12: N/D-N/D.
Impact Factor: 1.801
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* Peptides reproducing the ApoA-I 141-164 region: Studies on Hpt recognition (472 views)
D'Andrea LD, Spagnuolo M, De Stefano A, Morra M, Carlucci A, Del Gatto A, Caso P, Pedone C, Abrescia P, Benedetti E
Understanding Biology Using Peptides, 2006; N/D: N/D-N/D.
Impact Factor: 2.614
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* Characterization of a novel RGD-containing peptide with improved selectivity for imaging alpha v beta 3 integrin expression (542 views)
Del Vecchio S, Zannetti A, Del Gatto A, Grieco P, Iommelli F, Zaccaro L, Panico M, Saviano M, Blystone SD, Pedone C, Salvatore M
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
Impact Factor: 3.883
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* A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: A conformational study (769 views)
De Capua A, Del Gatto A, Zaccaro L, Saviano G, Carlucci A, Livigni A, Gedressi C, Tancredi T, Pedone C, Saviano M
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 459-466.
Impact Factor: 2.863
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* Development of peptides able to modulate the interaction of AKAP121 with mitochondria (516 views)
Saviano M, Zaccaro L, Benedetti E, Pedone C, Del Gatto A, Feliciello A, Affaiatati A, Avvedimento EV
Peptide Revolution, 2004; N/D: N/D-N/D.
Impact Factor: 4.659
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