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Emma Langella
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Researcher
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Naples - Castellino
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Via Pietro Castellino 111, 80131 Naples - Italy
E-mail
emma.langella
cnr.it
▼
Structure and function of proteins involved in physio-pathologic processes
▼
Carbonic Anhydrase IX as target for the development of new anti-tumour drugs
Buonanno Martina
Monti Simona Maria
Langella Emma
Di Fiore Anna
D'Ambrosio Katia
De Simone Giuseppina
Alterio Vincenzo
▼
Biomolecules able to modulate the VEGF-dependent angiogenesis
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
Diana Donatella
Di Gaetano Sonia
▼
A multi-targeting approach to fight COVID-19
Zaccaro Laura
Del Gatto Annarita
Pedone EmiliaMaria
Pirone Luciano
Di Gaetano Sonia
▼
Galectins: Structure, function and therapeutic potential inhibitors
Pedone EmiliaMaria
Di Gaetano Sonia
Pirone Luciano
▼
Carbonic Anhydrase family as target for rational drug design
Monti Simona Maria
De Simone Giuseppina
Alterio Vincenzo
▼
Characterization of the KCTD protein family: key factors in several biological processes
Pedone EmiliaMaria
Vitagliano Luigi
Di Gaetano Sonia
Pirone Luciano
▼
Chemical protein synthesis and modification for biomedical applications
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
▼
Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives
Pedone EmiliaMaria
Di Gaetano Sonia
Diana Donatella
Pirone Luciano
▼
Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications
Maglio Ornella
Diana Donatella
Leone Marilisa
▼
Structural characterization of the porphyrins/proteasome interaction
Diana Donatella
▼
Axl and Gas6 targeting for therapeutic and diagnostic applications
De Rosa Lucia
D'Andrea Luca Domenico
Di Stasi Rossella
▼
Drug discovery by mirror-image phage display
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
▼
Analysis of Sam domain druggability through computational and experimental studies
Leone Marilisa
Palumbo Rosanna
Pedone EmiliaMaria
Pirone Luciano
▼
Targeting Sam-Sam interactions mediated by EphA2 receptor: design and evaluation of peptide inhibitors
Leone Marilisa
Marasco Daniela
Palumbo Rosanna
Pedone EmiliaMaria
Pirone Luciano
▼
Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
Musumeci Domenica
Vicidomini Caterina
Palumbo Rosanna
Roviello Giovanni Nicola
▼
Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and functional characterization of Protein-Protein and DNA-protein Interaction networks in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and structural insights on Chromatin Assembly Factor 1 in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
Di Fiore Anna
D'Ambrosio Katia
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Targeting Of Protein-Protein Interactions For Therapeutic Purposes
Ruvo Menotti
Sandomenico Annamaria
Doti Nunzianna
▼
Cancer Diseases
▼
Gadd45 beta and its implication in chronic inflammation
Ruvo Menotti
Monti Simona Maria
▼
Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions
D'Ambrosio Katia
Vitagliano Luigi
Pedone EmiliaMaria
De Simone Giuseppina
Esposito Luciana
Alterio Vincenzo
▼
Characterization of the KCTD protein family: key factors in several biological processes
Pedone EmiliaMaria
Vitagliano Luigi
Di Gaetano Sonia
Pirone Luciano
▼
Characterization of neurotoxic and neuroprotective factors by using computational methodologies
Vitagliano Luigi
Esposito Luciana
▼
Monoclonal Antibodies for therapeutic and diagnostic applications
Ruvo Menotti
▼
Targeted Drug Delivery by integrin avb3 antagonist
Panico Mariarosaria
Zaccaro Laura
Zannetti Antonella
▼
Chemical protein synthesis and modification for biomedical applications
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
▼
Biomolecules able to modulate the VEGF-dependent angiogenesis
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
Diana Donatella
Di Gaetano Sonia
▼
Imaging Tumor Acidosis
Longo Dario Livio
▼
Bioactive peptide-membrane assemblies
No results.
▼
Carbonic Anhydrase IX as target for the development of new anti-tumour drugs
Buonanno Martina
Monti Simona Maria
Langella Emma
Di Fiore Anna
D'Ambrosio Katia
De Simone Giuseppina
Alterio Vincenzo
▼
Clinical Oncology
De Rosa Viviana
Iommelli Francesca
Salvatore Barbara
Del Vecchio Silvana
Fonti Rosa
▼
Translational Molecular Imaging in Cancer
Del Vecchio Silvana
Fonti Rosa
Panico Mariarosaria
De Rosa Viviana
Iommelli Francesca
▼
Molecular imaging for personalized therapy in oncology
Del Vecchio Silvana
Fonti Rosa
Iommelli Francesca
De Rosa Viviana
▼
Modeling radiation induced normal tissue effects
Pacelli Roberto
Conson Manuel
Palma Giuseppe
Liuzzi Raffaele
Cella Laura
▼
Evaluation of new molecular probes by preclinical imaging
Gargiulo Sara
▼
Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
Musumeci Domenica
Vicidomini Caterina
Palumbo Rosanna
Roviello Giovanni Nicola
▼
Brain segmentation for radiation oncology application
Quarantelli Mario
Comerci Marco
Pacelli Roberto
Conson Manuel
Liuzzi Raffaele
Cella Laura
▼
Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
De Luca Stefania
▼
Drug discovery by mirror-image phage display
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
▼
Axl and Gas6 targeting for therapeutic and diagnostic applications
De Rosa Lucia
D'Andrea Luca Domenico
Di Stasi Rossella
▼
Macromolecules for biomedical and biotechnological applications
▼
Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives
Pedone EmiliaMaria
Di Gaetano Sonia
Diana Donatella
Pirone Luciano
▼
A multi-targeting approach to fight COVID-19
Zaccaro Laura
Del Gatto Annarita
Pedone EmiliaMaria
Pirone Luciano
Di Gaetano Sonia
▼
Galectins: Structure, function and therapeutic potential inhibitors
Pedone EmiliaMaria
Di Gaetano Sonia
Pirone Luciano
▼
Characterization of the KCTD protein family: key factors in several biological processes
Pedone EmiliaMaria
Vitagliano Luigi
Di Gaetano Sonia
Pirone Luciano
▼
Chemical protein synthesis and modification for biomedical applications
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
▼
Biomolecules able to modulate the VEGF-dependent angiogenesis
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
Diana Donatella
Di Gaetano Sonia
▼
Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications
Maglio Ornella
Diana Donatella
Leone Marilisa
▼
Axl and Gas6 targeting for therapeutic and diagnostic applications
De Rosa Lucia
D'Andrea Luca Domenico
Di Stasi Rossella
▼
Generation of innovative scaffolds by manipulating hyperstable proteins
Ruggiero Alessia
Berisio Rita
Vitagliano Luigi
▼
The fine structure of proteins as a new tool for protein structure validation, quality assessment, and prediction
Vitagliano Luigi
Esposito Luciana
▼
Carbonic Anhydrase IX as target for the development of new anti-tumour drugs
Buonanno Martina
Monti Simona Maria
Langella Emma
Di Fiore Anna
D'Ambrosio Katia
De Simone Giuseppina
Alterio Vincenzo
▼
Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and functional characterization of Protein-Protein and DNA-protein Interaction networks in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and structural insights on Chromatin Assembly Factor 1 in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
Di Fiore Anna
D'Ambrosio Katia
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Plant polypeptides as natural enhancers of biostimulation
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
De Luca Stefania
▼
Protein-based biotherapeutics
Sandomenico Annamaria
Doti Nunzianna
Ruvo Menotti
▼
Understanding SARS-CoV-2 interaction with its host of for therapeutic applications
Squeglia Flavia
Ruggiero Alessia
Romano Maria
Berisio Rita
▼
Small molecules and peptides/modified peptides for diagnostic, therapeutic and biotechnological applications
▼
Biomolecules able to modulate the VEGF-dependent angiogenesis
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
Diana Donatella
Di Gaetano Sonia
▼
New peptide–based molecules as NGF mimetics in the therapy of neurological dysfunctions
Del Gatto Annarita
Zaccaro Laura
▼
Peptide-based molecules for αvβ3 integrin modulation in Th17 cells-dependent demyelinating diseases
Del Gatto Annarita
Zaccaro Laura
▼
Development of integrin subtypes selective ligands: from a first rationally designed peptide to a wide range of molecules
Di Gaetano Sonia
Zaccaro Laura
Del Gatto Annarita
Zannetti Antonella
▼
Design of New FSHR-Specific Peptides for therapeutic and diagnostic applications
Del Gatto Annarita
Zaccaro Laura
▼
New synthetic molecules for active targeting of multifunctional theranostic nanosystems
Zaccaro Laura
Del Gatto Annarita
▼
Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications
Maglio Ornella
Diana Donatella
Leone Marilisa
▼
Galectins: Structure, function and therapeutic potential inhibitors
Pedone EmiliaMaria
Di Gaetano Sonia
Pirone Luciano
▼
Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives
Pedone EmiliaMaria
Di Gaetano Sonia
Diana Donatella
Pirone Luciano
▼
A multi-targeting approach to fight COVID-19
Zaccaro Laura
Del Gatto Annarita
Pedone EmiliaMaria
Pirone Luciano
Di Gaetano Sonia
▼
Axl and Gas6 targeting for therapeutic and diagnostic applications
De Rosa Lucia
D'Andrea Luca Domenico
Di Stasi Rossella
▼
Drug discovery by mirror-image phage display
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
▼
Peptides of therapeutic interest with antimicrobial and/ or antitumoral activity
Pedone EmiliaMaria
Di Gaetano Sonia
Pirone Luciano
▼
Analysis of Sam domain druggability through computational and experimental studies
Leone Marilisa
Palumbo Rosanna
Pedone EmiliaMaria
Pirone Luciano
▼
Targeting Sam-Sam interactions mediated by EphA2 receptor: design and evaluation of peptide inhibitors
Leone Marilisa
Marasco Daniela
Palumbo Rosanna
Pedone EmiliaMaria
Pirone Luciano
▼
Environmental chemistry & human health. Computational studies. Synthesis of small molecules, modified peptides and nucleobase-decorated peptides. Spectroscopic and computational investigation on the potential of natural products in biomedicine. Nucleic acid and protein binding studies
Musumeci Domenica
Vicidomini Caterina
Palumbo Rosanna
Roviello Giovanni Nicola
▼
Plant polypeptides as natural enhancers of biostimulation
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
De Luca Stefania
▼
Design and screening of molecular repertoires as a source for new bioactive compounds
Doti Nunzianna
Sandomenico Annamaria
Ruvo Menotti
▼
Targeting Of Protein-Protein Interactions For Therapeutic Purposes
Ruvo Menotti
Sandomenico Annamaria
Doti Nunzianna
▼
Carbonic Anhydrase IX as target for the development of new anti-tumour drugs
Buonanno Martina
Monti Simona Maria
Langella Emma
Di Fiore Anna
D'Ambrosio Katia
De Simone Giuseppina
Alterio Vincenzo
▼
Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and functional characterization of Protein-Protein and DNA-protein Interaction networks in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and structural insights on Chromatin Assembly Factor 1 in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
Di Fiore Anna
D'Ambrosio Katia
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Plant polypeptides as natural enhancers of biostimulation
Buonanno Martina
Langella Emma
Monti Simona Maria
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*
Zeta-carbonic anhydrases show CS(2) hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?
(
162 views
)
Alterio V
,
Langella E
,
Buonanno M
,
Esposito D
, Nocentini A, Berrino E, Bua S, Polentarutti M, Supuran CT,
Monti SM
,
De Simone G
Comput Struct Biotechnol J (ISSN: 2001-0370linking)
,
2021 Jun 5;
19: 3427-3436.
Impact Factor:
7.271
View
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*
Cadmium-containing carbonic anhydrase CDCA1 in marine diatom Thalassiosira weissflogii
(
857 views
)
Alterio V
,
Langella E
,
De Simone G
,
Monti SM
Mar Drugs (ISSN: 1660-3397, 1660-3397linking)
,
2015 Mar 25;
13(4): 1688-1697.
Impact Factor:
3.345
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*
Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii
(
617 views
)
Alterio V
,
Langella E
, Viparelli F, Vullo D, Ascione G, Dathan NA, Morel FM, Supuran CT,
De Simone G
,
Monti SM
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic)
,
2012 May;
94(5): 1232-1241.
Impact Factor:
3.142
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*
Insights Into The Mechanism Of Interaction Between Trehalose-Conjugated Beta-Sheet Breaker Peptides And Aβ(1-42) Fibrils By Molecular Dynamics Simulations
(
997 views
)
Autiero I
,
Langella E
, Saviano M
Mol Biosyst (ISSN: 1742-206x, 1742-2206, 1742-2051linking)
,
2013 Nov;
9(11): 2835-2841.
Impact Factor:
3.18
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*
Conformational studies of chiral D-Lys-PNA and achiral PNA system in binding with DNA or RNA through a molecular dynamics approach
(
674 views
)
Autiero I
, Saviano M,
Langella E
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking)
,
2015 Feb 16;
91: 109-117.
Impact Factor:
3.902
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*
In silico investigation and targeting of amyloid beta oligomers of different size
(
608 views
)
Autiero I
, Saviano M,
Langella E
Mol Biosyst (ISSN: 1742-206x, 1742-2051electronic, 1742-2051linking)
,
2013 Aug;
9(8): 2118-2124.
Impact Factor:
3.18
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*
Molecular Dynamics Simulations Of Pna-Pna And Pna-Dna Duplexes By The Use Of New Parameters Implemented In The Gromacs Package: A Conformational And Dynamics Study
(
1237 views
)
Autiero I
, Saviano M,
Langella E
Phys Chem Chem Phys (ISSN: 1463-9076, 1463-3907, 1463-9084electronic)
,
2014 Feb 7;
16(5): 1868-1874.
Impact Factor:
4.493
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*
A computational protocol to probe the role of solvation effects on the reduction potential of azurin mutants
(
446 views
)
Barone V, De Rienzo F,
Langella E
, Menziani MC, Rega N, Sola M
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic)
,
2006 Jan 1;
62(1): 262-269.
Impact Factor:
3.73
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*
Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein
(
477 views
)
Buonanno M
, Coppola M, Di Lelio I, Molisso D,
Leone M
, Pennacchio F,
Langella E
, Rao R,
Monti SM
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking)
,
2018 Mar;
27(3): 620-632.
Impact Factor:
2.937
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*
The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior
(
450 views
)
Buonanno M
,
Di Fiore A
,
Langella E
, D’ambrosio K, Supuran CT,
Monti SM
,
De Simone G
Int J Mol Sc (ISSN: 1661-6596, 1422-0067, 1422-0067electronic)
,
2018 May;
19(6): 19-24.
Impact Factor:
3.687
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*
Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements
(
459 views
)
Buonanno M
,
Langella E
, Zambrano N, Succoio M, Sasso E,
Alterio V
,
Di Fiore A
,
Sandomenico A
, Supuran CT, Scaloni A,
Monti SM
,
De Simone G
Acs Chem Biol (ISSN: 1554-8929)
,
2017 Apr 19;
N/D: N/D-N/D.
Impact Factor:
4.592
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*
A novel member of the protein disulfide oxidoreductase family from Aeropyrum pernix K1: Structure, function and electrostatics
(
668 views
)
D'Ambrosio K
,
Pedone E
,
Langella E
,
De Simone G
, Rossi M,
Pedone C
, Bartolucci S
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic)
,
2006 Sep 29;
362(4): 743-752.
Impact Factor:
4.89
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*
Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach
(
307 views
)
De Simone G
,
Di Fiore A
, Truppo E,
Langella E
, Vullo D, Supuran CT,
Monti SM
J Enzym Inhib Med Ch (ISSN: 1475-6366linking, 1475-6374electronic)
,
2019 Dec;
34(1): 1506-1510.
Impact Factor:
4.027
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*
Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations
(
319 views
)
De Simone G
,
Langella E
,
Esposito D
, Supuran CT,
Monti SM
, Winum JY,
Alterio V
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking)
,
2017 Dec;
32(1): 1002-1011.
Impact Factor:
3.638
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*
Biochemical, structural, and computational studies of a γ-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei
(
81 views
)
Di Fiore A
, De Luca V,
Langella E
, Nocentini A,
Buonanno M
,
Monti SM
, Supuran CT, Capasso C,
De Simone G
Comput Struct Biotechnol J (ISSN: 2001-0370linking)
,
2022 Jul 27;
20: 4185-4194.
Impact Factor:
6.155
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*
Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe
(
361 views
)
Honarvar H, Calce E,
Doti N
,
Langella E
, Orlova A, Buijs J, D’amato V, Bianco R, Saviano M, Tolmachev V,
De Luca S
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic)
,
2018 Feb 14;
8(1): 2998-2998.
Impact Factor:
4.259
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*
Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity
(
321 views
)
Langella E
,
Alterio V
,
D'Ambrosio K
, Cadoni R, Winum JY, Supuran CT,
Monti SM
,
De Simone G
,
Di Fiore A
J Enzym Inhib Med Ch (ISSN: 1475-6366linking, 1475-6374electronic)
,
2019 Dec;
34(1): 1498-1505.
Impact Factor:
4.027
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*
Intrinsically disordered features of carbonic anhydrase IX proteoglycan-like domain
(
154 views
)
Langella E
,
Buonanno M
,
De Simone G
,
Monti SM
Cell Mol Life Sci (ISSN: 1420-682xlinking)
,
2020;
21: 8405-8405.
Impact Factor:
6.496
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*
Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX
(
394 views
)
Langella E
,
Buonanno M
, Vullo D, Dathan N,
Leone M
, Supuran C,
De Simone G
,
Monti SM
Cell Mol Life Sci (ISSN: 1420-682xlinking)
,
2018 Sep;
75(17): 3283-3296.
Impact Factor:
6.721
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*
Structural identification of an HER2 receptor model binding pocket to optimize lead compounds: a combined experimental and computational approach
(
430 views
)
Langella E
, Calce E, Saviano M,
De Luca S
Mol Biosyst (ISSN: 1742-206x)
,
2016 Jun 21;
12(7): 2159-2167.
Impact Factor:
2.781
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*
A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases
(
410 views
)
Langella E
,
D'Ambrosio K
, D'Ascenzio M, Carradori S,
Monti SM
, Supuran CT,
De Simone G
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic)
,
2016 Jan 4;
22(1): 97-100.
Impact Factor:
5.317
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A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
(
167 views
)
Langella E
,
Esposito D
,
Monti SM
, Supuran CT,
De Simone G
,
Alterio V
Biology (ISSN: 2079-7737linking)
,
2023 Feb 10;
12 (2 ): N/D-N/D.
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Checking the pH-induced conformational transition of prion protein by molecular dynamics simulations: Effect of protonation of histidine residues
(
629 views
)
Langella E
,
Improta R
, Barone V
Biophysical Journal (ISSN: 0006-3495, 1542-0086)
,
2004 Dec;
87(6): 3623-3632.
Impact Factor:
4.585
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Conformational and spectroscopic analysis of the tyrosyl radical dipeptide analogue in the gas phase and in aqueous solution by a density functional/continuum solvent model
(
874 views
)
Langella E
,
Improta R
, Barone V
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126)
,
2002 Sep 25;
124(38): 11531-11540.
Impact Factor:
6.201
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Assessing the acid-base and conformational properties of histidine residues in human prion protein (125-228) by means of pKα calculations and molecular dynamics simulations
(
804 views
)
Langella E
,
Improta R
, Crescenzi O, Barone V
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic)
,
2006 Jul 1;
64(1): 167-177.
Impact Factor:
3.73
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Probing The Peptidylglycine Alpha-Hydroxylating Monooxygenase Active Site With Novel 4-Phenyl-3-Butenoic Acid Based Inhibitors
(
490 views
)
Langella E
, Pierre S, Ghattas W, Giorgi M, Réglier M, Saviano M,
Esposito L
, Hardré R
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic)
,
2010 Sep 3;
5(9): 1568-1576.
Impact Factor:
3.306
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Exploring Phm Active Site: Characterization Of Novel Pba-Derived Inhibitors Using A Combined Experimental And Computational Approach
(
416 views
)
Langella E
, Pierre S, Ghattas W, Giorgi M, Rglier M, Saviano M, Esposito L, Hardr R
Chemmedchem
,
2010;
5: 1568-1576.
Impact Factor:
3.046
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Conformational analysis of the tyrosine dipeptide analogue in the gas phase and in aqueous solution by a density functional/continuum solvent model
(
430 views
)
Langella E
, Rega N,
Improta R
, Crescenzi O, Barone V
J Comput Chem (ISSN: 0192-8651, 1096-987xelectronic)
,
2002 Apr 30;
23(6): 650-661.
Impact Factor:
2.931
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Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus
(
575 views
)
Limauro D,
D'Ambrosio K
,
Langella E
,
De Simone G
, Galdi I,
Pedone C
,
Pedone E
, Bartolucci S
Biochimie (ISSN: 1638-6183, 0300-9084, 1638-6183electronic)
,
2010 Oct;
92(10): 1435-1444.
Impact Factor:
3.787
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Seeking for binding determinants of the prion protein to human plasminogen
(
539 views
)
Menziani MC, De Benedetti PG,
Langella E
, Barone V
Mol Phys (ISSN: 0026-8976)
,
2003;
101(17): 2763-2773.
Impact Factor:
1.591
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Structural Insights on Tiny Peptide Nucleic Acid (PNA) Analogues of miRNA-34a: An in silico and Experimental Integrated Approach
(
168 views
)
Moccia M,
Mercurio FA
,
Langella E
, Piacenti V,
Leone M
, Adamo MFA, Saviano M
Front Chem (ISSN: 2296-2646linking)
,
2020 Nov 23;
8: 568575-568575.
Impact Factor:
3.693
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Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage
(
465 views
)
Monti DM,
De Simone G
,
Langella E
, Supuran CT,
Di Fiore A
,
Monti SM
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking)
,
2017 Dec;
32(1): 5-12.
Impact Factor:
3.638
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The Amazing World of IDPs in Human Diseases
(
132 views
)
Monti SM
,
De Simone G
,
Langella E
,
Monti SM
,
De Simone G
,
Langella E
Biomolecules (ISSN: 2218-273xlinking)
,
2021 Feb 23;
11(2): 333-333.
Impact Factor:
4.879
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Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation
(
838 views
)
Palmieri G, Bergamo P, Luini A,
Ruvo M
, Gogliettino M,
Langella E
, Saviano M, Hegde RN,
Sandomenico A
, Rossi M
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking)
,
2011 Oct 10;
6(10): e25888-e25888.
Impact Factor:
4.092
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First archaeal PEPB-serine protease inhibitor from sulfolobus solfataricus with noncanonical amino acid sequence in the reactive-site loop
(
488 views
)
Palmieri G, Catara G, Saviano M,
Langella E
, Gogliettino M, Rossi M
J Proteome Res (ISSN: 1535-3893)
,
2009 Jan;
8(1): 327-334.
Impact Factor:
5.132
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A novel class of protease targets of phosphatidylethanolamine-binding proteins (PEBP): A study of the acylpeptide hydrolase and the PEBP inhibitor from the archaeon Sulfolobus solfataricus
(
429 views
)
Palmieri G,
Langella E
, Gogliettino M, Saviano M, Pocsfalvi G, Rossi M
Mol Biosyst (ISSN: 1742-206x)
,
2010;
6(12): 2498-2507.
Impact Factor:
3.825
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Insight into the stereospecificity of short-chain Thermus thermophilus alcohol dehydrogenase showing pro-S hydride transfer and Prelog enantioselectivity
(
708 views
)
Pennacchio A, Giordano A,
Esposito L
,
Langella E
, Rossi M, Raia CA
Protein Pept Lett (ISSN: 0929-8665, 1875-5305)
,
2010 Apr;
17(4): 437-443.
Impact Factor:
1.849
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A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a
(
306 views
)
Piacenti V,
Langella E
,
Autiero I
, Nolan JC, Piskareva O, Adamo MFA, Saviano M, Moccia M
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic)
,
2019 Oct;
91: 103165-103165.
Impact Factor:
3.9
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Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments
(
758 views
)
Ronga L,
Langella E
, Palladino P,
Marasco D
, Tizzano B, Saviano M,
Pedone C
,
Improta R
,
Ruvo M
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic)
,
2007 Feb 15;
66(3): 707-715.
Impact Factor:
3.354
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Development of new molecules that compete with p53 for Binding to TFIIH
(
480 views
)
Zaccaro L
,
Del Gatto A
, Saviano M,
Langella E
, Langlois C, Di Lello P, Baffreau J, Mas C, Legault P, Omichinski JG,
Pedone C
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print)
,
2008 Sep;
14(8): N/D-N/D.
Impact Factor:
1.654
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40
Records (
38
excluding Abstracts).
Total impact factor:
156.963
(
151.05
excluding Abstracts).
Total 5 year impact factor:
142.601
(
135.972
excluding Abstracts).
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Emma Langella
on Monday 28 October 2019, 10:53:33
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