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Alessia Ruggiero
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Naples - Castellino
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Via Pietro Castellino 111, 80131 Naples - Italy
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alessia.ruggiero
unina.it
▼
Biomolecules for biosensing applications
▼
Generation of innovative scaffolds by manipulating hyperstable proteins
Ruggiero Alessia
Berisio Rita
Vitagliano Luigi
▼
Syntethic metalloproteins and peptides for biosensing applications
Maglio Ornella
▼
Cell wall recognition events for biosensors development
Squeglia Flavia
Ruggiero Alessia
Romano Maria
Berisio Rita
▼
Multispecific Human Albumin Nanoparticles (NP-HSA) decorated with multiple molecular cues for the specific and controlled delivery of cytotoxic agents
Sandomenico Annamaria
Ruvo Menotti
▼
Macromolecules for biomedical and biotechnological applications
▼
Protein-Protein-Interaction network–disease relationship, pathogenicity and therapeutic perspectives
Pedone EmiliaMaria
Di Gaetano Sonia
Diana Donatella
Pirone Luciano
▼
A multi-targeting approach to fight COVID-19
Zaccaro Laura
Del Gatto Annarita
Pedone EmiliaMaria
Pirone Luciano
Di Gaetano Sonia
▼
Galectins: Structure, function and therapeutic potential inhibitors
Pedone EmiliaMaria
Di Gaetano Sonia
Pirone Luciano
▼
Characterization of the KCTD protein family: key factors in several biological processes
Pedone EmiliaMaria
Vitagliano Luigi
Di Gaetano Sonia
Pirone Luciano
▼
Chemical protein synthesis and modification for biomedical applications
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
▼
Biomolecules able to modulate the VEGF-dependent angiogenesis
D'Andrea Luca Domenico
De Rosa Lucia
Di Stasi Rossella
Diana Donatella
Di Gaetano Sonia
▼
Biomolecular NMR: structural studies of proteins and peptides and drug discovery applications
Maglio Ornella
Diana Donatella
Leone Marilisa
▼
Axl and Gas6 targeting for therapeutic and diagnostic applications
De Rosa Lucia
D'Andrea Luca Domenico
Di Stasi Rossella
▼
Generation of innovative scaffolds by manipulating hyperstable proteins
Ruggiero Alessia
Berisio Rita
Vitagliano Luigi
▼
The fine structure of proteins as a new tool for protein structure validation, quality assessment, and prediction
Vitagliano Luigi
Esposito Luciana
▼
Carbonic Anhydrase IX as target for the development of new anti-tumour drugs
Buonanno Martina
Monti Simona Maria
Langella Emma
Di Fiore Anna
D'Ambrosio Katia
De Simone Giuseppina
Alterio Vincenzo
▼
Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and functional characterization of Protein-Protein and DNA-protein Interaction networks in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
D'Ambrosio Katia
Di Fiore Anna
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Biochemical and structural insights on Chromatin Assembly Factor 1 in physio/pathological events
De Simone Giuseppina
Alterio Vincenzo
Di Fiore Anna
D'Ambrosio Katia
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Plant polypeptides as natural enhancers of biostimulation
Buonanno Martina
Langella Emma
Monti Simona Maria
▼
Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
De Luca Stefania
▼
Protein-based biotherapeutics
Sandomenico Annamaria
Doti Nunzianna
Ruvo Menotti
▼
Understanding SARS-CoV-2 interaction with its host of for therapeutic applications
Squeglia Flavia
Ruggiero Alessia
Romano Maria
Berisio Rita
▼
Nanoparticles and biomaterials
▼
Structural characterization of self-assembling systems of biomedical and biotechnological interest
Vitagliano Luigi
Esposito Luciana
Ruggiero Alessia
▼
Syntethic metalloproteins and peptides for biosensing applications
Maglio Ornella
▼
Chemical modification of natural molecules, such as peptides and polysaccharides, to be employed as therapeutic agents as well as sensor diagnostic tools
De Luca Stefania
▼
Molecules of immunologic interest
▼
BactiVax – Innovative vaccine development against bacterial pathogens
Romano Maria
Squeglia Flavia
Ruggiero Alessia
Berisio Rita
▼
Monoclonal Antibodies and recombinant fragments for therapeutic and diagnostic applications
Sandomenico Annamaria
Ruvo Menotti
Doti Nunzianna
▼
Generation of innovative scaffolds by manipulating hyperstable proteins
Ruggiero Alessia
Berisio Rita
Vitagliano Luigi
▼
Structural characterization of self-assembling systems of biomedical and biotechnological interest
Vitagliano Luigi
Esposito Luciana
Ruggiero Alessia
▼
Cell wall recognition events for biosensors development
Squeglia Flavia
Ruggiero Alessia
Romano Maria
Berisio Rita
▼
BactiVax – Innovative vaccine development against bacterial pathogens
Romano Maria
Squeglia Flavia
Ruggiero Alessia
Berisio Rita
▼
Understanding SARS-CoV-2 interaction with its host of for therapeutic applications
Squeglia Flavia
Ruggiero Alessia
Romano Maria
Berisio Rita
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*
Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation
(
222 views
)
Sandomenico A
,
Ruggiero A
,
Iaccarino E
, Oliver A,
Squeglia F
, Moreira M,
Esposito L
,
Ruvo M
,
Berisio R
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic)
,
2023 May 10;
24(10): 500-519.
Impact Factor:
6.21
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*
A Structural View at Vaccine Development against M. tuberculosis
(
144 views
)
Romano M
,
Squeglia F
, Kramarska E, Barra G, Choi HG, Kim HJ,
Ruggiero A
,
Berisio R
Cells (ISSN: 2073-4409linking, 2073-4409electronic)
,
2023 Jan 14;
12(2): N/D-N/D.
Impact Factor:
7.7
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*
Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis
(
168 views
)
Ruggiero A
, Choi HG, Barra G,
Squeglia F
, Back YW, Kim HJ,
Berisio R
Front Mol Biosci (ISSN: 2296-889xlinking)
,
2022 Aug 11;
9: 964645-964645.
Impact Factor:
6.11
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*
Structure-Based Development of SARS-CoV-2 Spike Interactors
(
107 views
)
Squeglia F
,
Romano M
,
Esposito L
, Barra G, Campiglia P, Sala M, Scala MC,
Ruggiero A
,
Berisio R
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic)
,
2022 May 17;
23(10): N/D-N/D.
Impact Factor:
6.21
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*
Structural and Binding Properties of the Active Cell Wall Hydrolase RipA from M. tuberculosis, a Promising Biosensing Molecule for Early Warning Bacterial Detection
(
131 views
)
Squeglia F
,
Marasco D
,
Ruggiero A
, Testa G,
Esposito L
,
Berisio R
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic)
,
2022;
29(24): 4282-4292.
Impact Factor:
4.74
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*
Structural and Biochemical Characterization of Endo--1, 4-glucanase from Dictyoglomus thermophilum, a Hyperthermostable and Halotolerant Cellulase
(
209 views
)
(PDF
40 views
)
Berisio R
, Barra G,
Romano M
,
Squeglia F
,
Ruggiero A
Catalysts
,
2022;
302: N/D-N/D.
Impact Factor:
4.5
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*
AlphaFold-Predicted Structures of KCTD Proteins Unravel Previously Undetected Relationships among the Members of the Family
(
175 views
)
Esposito L
, Balasco N, Smaldone G,
Berisio R
,
Ruggiero A
,
Vitagliano L
Biomolecules (ISSN: 2218-273xlinking)
,
2021 Dec 10;
11(12): N/D-N/D.
Impact Factor:
6.06
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*
Members of the GADD45 Protein Family Show Distinct Propensities to form Toxic Amyloid-Like Aggregates in Physiological Conditions
(
126 views
)
Smaldone G, Caruso D,
Sandomenico A
,
Iaccarino E
, Focà A,
Ruggiero A
,
Ruvo M
,
Vitagliano L
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic)
,
2021 Oct 2;
22 (19 ): N/D-N/D.
Impact Factor:
2.598
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*
A structure-based approach for the development of a bicyclic peptide acting as a miniaturized anti-CD55 antibody
(
230 views
)
(PDF
45 views
)
Moreira M,
Ruggiero A
,
Iaccarino E
, Barra G,
Sandomenico A
,
Ruvo M
,
Berisio R
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic)
,
2021 May 17;
182: 1455-1462.
Impact Factor:
6.95
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*
Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins
(
201 views
)
Squeglia F
,
Romano M
,
Ruggiero A
, Maga G,
Berisio R
Front Chem (ISSN: 2296-2646linking)
,
2020 Dec 10;
8: 602162-602162.
Impact Factor:
3.693
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*
Guanidinium binding to proteins: The intriguing effects on the D1 and D2 domains of Thermotoga maritima Arginine Binding Protein and a comprehensive analysis of the Protein Data Bank
(
157 views
)
Cozzolino S, Balasco N, Vigorita M,
Ruggiero A
, Smaldone G, Del Vecchio P,
Vitagliano L
, Graziano G
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic)
,
2020 Nov 15;
163: 375-385.
Impact Factor:
5.162
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*
Development of a Protein Scaffold for Arginine Sensing Generated through the Dissection of the Arginine-Binding Protein from Thermotoga maritima
(
261 views
)
Smaldone G,
Ruggiero A
, Balasco N,
Vitagliano L
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596)
,
2020 Oct 12;
21(20): N/D-N/D.
Impact Factor:
4.556
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*
Structural and Functional Studies of a Klebsiella Phage Capsule Depolymerase Tailspike: Mechanistic Insights into Capsular Degradation
(
267 views
)
Squeglia F
, Maciejewska B, Łątka A,
Ruggiero A
, Briers Y, Drulis-kawa Z,
Berisio R
Structure (ISSN: 0969-2126linking, 1878-4186)
,
2020 Jun 2;
28(6): 613-624.
Impact Factor:
4.86
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*
A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping
(
954 views
)
Romano M
,
Ruggiero A
,
Squeglia F
, Maga G,
Berisio R
Cells (ISSN: 2073-4409linking, 2073-4409electronic)
,
2020 May 20;
9(5): 1297-1297.
Impact Factor:
6.6
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*
Structural features of HtpGMtb and HtpG-ESAT6Mtb vaccine antigens against tuberculosis: Molecular determinants of antigenic synergy and cytotoxicity modulation
(
228 views
)
(PDF
38 views
)
Moreira M,
Ruggiero A
,
Esposito L
, Choi HG, Kim HJ,
Berisio R
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic)
,
2020 May 4;
158: 305-317.
Impact Factor:
6.95
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The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima
(
253 views
)
Smaldone G,
Ruggiero A
, Balasco N, Abuhammad A,
Autiero I
, Caruso D,
Esposito D
, Ferraro G, Gelardi E, L , M , Moreira M, Quareshy M,
Romano M
, Saaret A, Selvam I,
Squeglia F
, Troisi R, Kroon-batenburg L, M , J ,
Esposito L
,
Berisio R
,
Vitagliano L
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xlinking)
,
2019 Nov 1;
75(Pt11): 707-713.
Impact Factor:
0.968
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*
Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests
(
348 views
)
Meccariello A, Salvemini M, Primo P, Hall B, Koskinioti P, Dalikova M, Gravina A, Gucciardino MA, Forlenza F, Gregoriou ME, Ippolito D,
Monti SM
, Petrella V, Perrotta MM, Schmeing S,
Ruggiero A
, Scolari F, Giordano E, Tsoumani KT, Marec F, Windbichler N, Arunkumar KP, Bourtzis K, Mathiopoulos KD, Ragoussis J,
Vitagliano L
, Tu Z, Papathanos PA, Robinson MD, Saccone G
Science (ISSN: 0036-8075linking)
,
2019 Sep 27;
365(6460): 1457-1460.
Impact Factor:
41.037
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*
Structure, stability and aggregation propensity of a Ribonuclease A-Onconase chimera
(
416 views
)
Esposito L
, Donnarumma F,
Ruggiero A
, Leone S,
Vitagliano L
, Picone D
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic)
,
2019 Jul 15;
133: 1125-1133.
Impact Factor:
4.784
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*
Binding and enzymatic properties of Ageritin, a fungal ribotoxin with novel zinc-dependent function
(
430 views
)
Ruggiero A
, Garcia-ortega L, Moreira M, Ragucci S, Landi N, Di Maro A,
Berisio R
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic)
,
2019 Jun 18;
136: 625-631.
Impact Factor:
4.78
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*
The Cell Wall Hydrolytic NlpC/P60 Endopeptidases in Mycobacterial Cytokinesis: A Structural Perspective
(
393 views
)
Squeglia F
, Moreira M,
Ruggiero A
,
Berisio R
Cells (ISSN: 2073-4409linking, 2073-4409electronic)
,
2019 Jun 18;
8(6): N/D-N/D.
Impact Factor:
5.7
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*
Loop size optimization induces a strong thermal stabilization of the thioredoxin fold
(
357 views
)
Ruggiero A
, Smaldone G,
Esposito L
, Balasco N,
Vitagliano L
Febs J (ISSN: 1742-464xlinking)
,
2019 May;
286(9): 1752-1764.
Impact Factor:
3.129
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*
The characterization of Thermotoga maritima Arginine Binding Protein variants demonstrates that minimal local strains have an important impact on protein stability
(
245 views
)
Balasco N, Smaldone G, Vigorita M, Del Vecchio P, Graziano G,
Ruggiero A
,
Vitagliano L
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic)
,
2019 Apr 29;
9(1): 6617-6617.
Impact Factor:
5.078
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*
Domain communication in Thermotoga maritima Arginine Binding Protein unraveled through protein dissection
(
327 views
)
Smaldone G, Balasco N, Vigorita M,
Ruggiero A
, Cozzolino S,
Berisio R
, Del Vecchio P, Graziano G,
Vitagliano L
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic)
,
2018 Nov;
119: 758-769.
Impact Factor:
3.909
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*
Local structural motifs in proteins: Detection and characterization of fragments inserted in helices
(
371 views
)
Balasco N, Smaldone G,
Ruggiero A
, De Simone A,
Vitagliano L
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic)
,
2018 Oct 15;
118(PtB): 1924-1930.
Impact Factor:
3.909
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*
Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest
(
568 views
)
Squeglia F
,
Ruggiero A
,
Berisio R
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print)
,
2018 Oct 11;
475(19): 3123-3140.
Impact Factor:
4.897
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*
Structural and enzymatic properties of Ageritin, a novel metal-dependent ribotoxin-like protein with antitumor activity
(
477 views
)
Ruggiero A
, Garcia-ortega L, Ragucci S, Russo R, Landi N,
Berisio R
, Di Maro A
Bba-Gen Subjects (ISSN: 1872-8006electronic, 0304-4165linking, 0304-4165print)
,
2018 Sep 18;
1862(12): 2888-2894.
Impact Factor:
3.679
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*
Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization
(
383 views
)
Smaldone G,
Berisio R
, Balasco N, D'Auria S,
Vitagliano L
,
Ruggiero A
Bba-Gen Subjects (ISSN: 1570-9639print, 1570-9639linking, 0005-2728)
,
2018 May 31;
1866(9): 952-962.
Impact Factor:
2.773
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*
Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation
(
255 views
)
Squeglia F
,
Ruggiero A
,
Berisio R
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic)
,
2018 Feb 21;
24 (11 ): 2533-2546.
Impact Factor:
5.476
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*
A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics
(
347 views
)
Squeglia F
,
Ruggiero A
, De Simone A,
Berisio R
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking)
,
2018 Feb;
27(2): 369-380.
Impact Factor:
2.523
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*
The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis
(
445 views
)
Squeglia F
,
Berisio R
,
Ruggiero A
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xelectronic, 2053-230xlinking)
,
2018 Jan 1;
74(Pt1): 1-5.
Impact Factor:
0.8
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*
Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation
(
621 views
)
(PDF
257 views
)
Squeglia F
,
Ruggiero A
,
Berisio R
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking)
,
2018;
24: 2533-2546.
Impact Factor:
5.317
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*
Editorial: Molecular Scenarios Behind Infectious Diseases
(
540 views
)
Berisio R
,
Squeglia F
,
Ruggiero A
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic)
,
2017 Nov 24;
24(36): 3939-3941.
Impact Factor:
3.469
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*
Molecular players in Tuberculosis drug development: another break in the cell wall
(
495 views
)
Squeglia F
,
Romano M
,
Ruggiero A
,
Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic)
,
2017 Nov 24;
24(36): 3954-3969.
Impact Factor:
3.469
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*
Structural Versatility of Hepatitis C Virus Proteins: Implications for the Design of Novel Anti-HCV Intervention Strategies
(
396 views
)
Balasco N,
Barone D
,
Sandomenico A
,
Ruggiero A
,
Doti N
,
Berisio R
,
Ruvo M
,
Vitagliano L
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic)
,
2017 Nov 24;
24(36): 4081-4101.
Impact Factor:
3.469
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*
Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis
(
539 views
)
Ruggiero A
,
Squeglia F
,
Romano M
,
Vitagliano L
, De Simone A,
Berisio R
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking)
,
2017 May;
35(6): 1322-1330.
Impact Factor:
3.107
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The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation
(
433 views
)
Dennehy R, RomanoM,
Ruggiero A
, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA,
Berisio R
, Mcclean S
Cell Microbiol (ISSN: 1462-5814)
,
2017 May;
19(5): e12691-e12691.
Impact Factor:
4.41
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*
Molecular mechanisms of defense response induced by chitin oligosaccharides
(
462 views
)
Berisio R
,
Ruggiero A
,
Squeglia F
, Esposito C,
Molinaro A
, Silipo A, Marchetti R, Shibuya N
Research Reports
,
2017;
N/D: N/D-N/D.
Impact Factor:
0
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Proline 235 plays a key role in the regulation of the oligomeric states of Thermotoga maritima Arginine Binding Protein
(
733 views
)
Smaldone G, Vigorita M,
Ruggiero A
, Balasco N, Dattelbaum JD, D'Auria S, Del Vecchio P, Graziano G,
Vitagliano L
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print)
,
2016 Jul;
1864(7): 814-824.
Impact Factor:
4.932
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Generation and characterization of monoclonal antibodies against a cyclic variant of Hepatitis C Virus E2 epitope 412-422
(
710 views
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(PDF
227 views
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Sandomenico A
, Leonardi A,
Berisio R
, Sanguigno L, Foca G, Foca A,
Ruggiero A
,
Doti N
, Muscariello L,
Barone D
, Farina C, Owsianka A,
Vitagliano L
, Patel AH,
Ruvo M
J Virol (ISSN: 0022-538x, 0022-538xlinking)
,
2016 Jan 27;
90(7): 3745-3759.
Impact Factor:
4.663
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Peptidoglycan-associated lipoprotein is a virulence factor that is involved in host cell attachment of Burkholderia cepacia complex
(
374 views
)
Dennehy R,
Romano M
,
Ruggiero A
, Troncoso CM, Fathy Y, Callaghan M, Valvano M,
Berisio R
, Mcclean S
Cellular Microbiology
,
2016;
inpress: N/D-N/D.
Impact Factor:
4.46
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Use of hydrolytic enzymes for algal biomass treatment
(
412 views
)
Ruggiero A
,
Squeglia F
,
Romano M
,
Berisio R
Current Biotechnology
,
2016;
5: 296-304.
Impact Factor:
2.922
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NMR Structure and Dynamics of the Resuscitation Promoting Factor RpfC Catalytic Domain
(
487 views
)
Maione V,
Ruggiero A
, Russo L, De Simone A, Pedone PV, Malgieri G,
Berisio R
, Isernia C
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking)
,
2015 Nov 17;
10(11): e0142807-e0142807.
Impact Factor:
3.057
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The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains
(
498 views
)
Ruggiero A
,
Squeglia F
,
Romano M
,
Vitagliano L
, De Simone A,
Berisio R
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print)
,
2015 Nov 5;
1860(2): 445-451.
Impact Factor:
4.864
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A product of RpfB and RipA joint enzymatic action promotes the resuscitation of dormant mycobacteria
(
694 views
)
Nikitushkin VD, Demina GR, Shleeva MO, Guryanova SV,
Ruggiero A
,
Berisio R
, Kaprelyants AS
Febs J (ISSN: 1742-464x)
,
2015 Apr 3;
282(13): 2500-2511.
Impact Factor:
4.237
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Exit from mycobacterial dormancy: a structural perspective
(
749 views
)
Squeglia F
,
Ruggiero A
,
Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic)
,
2015 Feb 9;
22(14): 1698-1709.
Impact Factor:
3.455
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Differential thermodynamic behaviours of the extra-cellular regions of two Ser/Thr PrkC kinases revealed by calorimetric studies
(
589 views
)
Berisio R
,
Squeglia F
,
Ruggiero A
, Petraccone L, Stellato MI, Del Vecchio P
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639)
,
2015 Feb 8;
1854(5): 402-409.
Impact Factor:
5.158
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Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine
(
606 views
)
Squeglia F
,
Ruggiero A
,
Romano M
,
Vitagliano L
,
Berisio R
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking)
,
2014 Sep;
70(9): 2295-2300.
Impact Factor:
14.1
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Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis
(
881 views
)
Calvanese L,
Falcigno L
, Maglione C,
Marasco D
,
Ruggiero A
,
Squeglia F
,
Berisio R
,
D'Auria G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print)
,
2014 Jul;
101(7): 712-719.
Impact Factor:
2.385
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A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima
(
829 views
)
Ruggiero A
, Dattelbaum JD, Staiano M,
Berisio R
, D'Auria S,
Vitagliano L
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking)
,
2014 May 15;
9(5): e96560-e96560.
Impact Factor:
3.234
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Temozolomide is an active agent in children with recurrent medulloblastoma/primitive neuroectodermal tumor: An Italian multi-institutional phase II trial
(
480 views
)
Cefalo G, Massimino M,
Ruggiero A
, Barone G, Ridola V, Spreafico F, Potepan P, Abate ME, Mascarin M, Garrè ML, Perilongo G, Madon E, Colosimo C, Riccardi R
Neuro-Oncology (ISSN: 1522-8517)
,
2014 May;
16(5): 748-753.
Impact Factor:
6.776
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Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization
(
1784 views
)
Hayafune M,
Berisio R
, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S,
Squeglia F
,
Ruggiero A
, Tokuyasu K,
Molinaro A
, Kaku H, Shibuya N
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print)
,
2014 Jan 21;
111(3): E404-E404.
Impact Factor:
9.674
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Structures of free and inhibited forms of the L, D-transpeptidase LdtMt1 from Mycobacterium tuberculosis
(
587 views
)
Correale S,
Ruggiero A
, Capparelli R,
Pedone E
,
Berisio R
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking)
,
2013 Sep;
69(Pt9): 1697-1706.
Impact Factor:
7.232
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Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses
(
740 views
)
Squeglia F
,
Romano M
,
Ruggiero A
,
Vitagliano L
, De Simone A,
Berisio R
Biophysical Journal (ISSN: 0006-3495, 1542-0086)
,
2013 Jun 4;
104(11): 2530-2539.
Impact Factor:
3.832
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Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis
(
567 views
)
Correale S,
Ruggiero A
,
Pedone E
,
Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309)
,
2013 Mar 1;
69(3): 253-256.
Impact Factor:
0.568
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Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis
(
726 views
)
Ruggiero A
, Marchant J,
Squeglia F
, Makarov V, De Simone A,
Berisio R
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking)
,
2013 Feb 1;
31(2): 195-205.
Impact Factor:
2.983
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Role of mutual interactions in the chemical and thermal stability of nucleophosmin NPM1 domains
(
412 views
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Marasco D
,
Ruggiero A
, Vascotto C, Poletto M, Scognamiglio PL, Tell G,
Vitagliano L
Biochemical And Biophysical Research Communications (ISSN: 0006-291x)
,
2013 Jan 11;
430(2): 523-528.
Impact Factor:
2.281
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Bacterial cell division regulation by Ser/Thr kinases: A structural perspective
(
766 views
)
Ruggiero A
, De Simone P, Smaldone G,
Squeglia F
,
Berisio R
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking)
,
2012 Dec;
13(8): 756-766.
Impact Factor:
2.326
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Resuscitation-promoting Factors (Rpf): In Search of Inhibitors
(
698 views
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Kaprelyants AS, Mukamolova GV,
Ruggiero A
, Makarov VA, Demina GR, Shleeva MO, Potapov VD, Shramko PA
Protein Pept Lett (ISSN: 0929-8665, 1875-5305)
,
2012 Oct;
19(10): 1026-1034.
Impact Factor:
1.994
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HIV p24 as Scaffold for Presenting Conformational HIV Env Antigens
(
668 views
)
Tagliamonte M,
Marasco D
,
Ruggiero A
, de Stradis A, Tornesello ML, Totrov M, Buonaguro FM, Buonaguro L
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking)
,
2012 Sep 17;
7(8): N/D-N/D.
Impact Factor:
3.73
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Enhanced crystallizability by protein engineering approaches: A general overview
(
2198 views
)
Ruggiero A
, Smaldone G,
Squeglia F
,
Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305)
,
2012 Jul;
19(7): 732-742.
Impact Factor:
1.994
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Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica
(
558 views
)
Di Maro A,
Berisio R
,
Ruggiero A
, Tamburino R, Severino V, Zacchia E, Parente A
Biochem Biophys Res Commun (ISSN: 0006-291x)
,
2012 May 11;
421(3): 514-520.
Impact Factor:
2.406
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Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability
(
476 views
)
Esposito L
,
Ruggiero A
, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A,
Vitagliano L
J Struct Biol (ISSN: 1047-8477, 1047-8477linking)
,
2012 Feb;
177(2): 506-512.
Impact Factor:
3.361
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Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy
(
486 views
)
Squeglia F
, Marchetti R,
Ruggiero A
, Lanzetta R,
Marasco D
, Dworkin J, Petoukhov M,
Molinaro A
,
Berisio R
, Silipo A
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126)
,
2011 Dec 28;
133(51): 20676-20679.
Impact Factor:
9.907
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Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein
(
808 views
)
Ruggiero A
, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS,
Berisio R
, D'Auria S,
Vitagliano L
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309)
,
2011 Nov 1;
67(11): 1462-1465.
Impact Factor:
0.506
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X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus
(
1070 views
)
Ruggiero A
,
Squeglia F
,
Marasco D
, Marchetti R,
Molinaro A
,
Berisio R
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking)
,
2011 Apr 1;
435(1): 33-41.
Impact Factor:
4.897
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Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis
(
539 views
)
Ruggiero A
,
Squeglia F
,
Pirone L
, Correale S,
Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309)
,
2011 Jan 1;
67(1): 164-168.
Impact Factor:
0.506
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Dynamical properties of cold shock protein A from Mycobacterium tuberculosis
(
588 views
)
D'Auria G
, Esposito C,
Falcigno L
, Calvanese L,
Iaccarino E
,
Ruggiero A
,
Pedone C
,
Pedone E
,
Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic)
,
2010 Nov 26;
402(4): 693-698.
Impact Factor:
2.595
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Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus
(
821 views
)
Ruggiero A
,
Squeglia F
, Izzo V, Silipo A,
Vitagliano L
,
Molinaro A
,
Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305)
,
2010 Oct;
17(10): 1296-1299.
Impact Factor:
1.849
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Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation
(
695 views
)
Ruggiero A
,
Marasco D
,
Squeglia F
, Soldini S,
Pedone E
,
Pedone C
,
Berisio R
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking)
,
2010 Sep 8;
18(9): 1184-1190.
Impact Factor:
6.337
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Elongation Factors Efia And Ef-Tu: Their Role In Translation And Beyond
(
745 views
)
Berisio R
,
Ruggiero A
,
Vitagliano L
Israel Journal Of Chemistry
,
2010 Jun;
50(1): 71-79.
Impact Factor:
2.561
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Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis
(
532 views
)
Ruggiero A
,
Squeglia F
, Esposito C,
Marasco D
,
Pedone E
,
Pedone C
,
Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305)
,
2010 Jan;
17(1): 70-73.
Impact Factor:
1.849
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The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves
(
492 views
)
Severino V, Chambery A, Di Maro A,
Marasco D
,
Ruggiero A
,
Berisio R
, Giansanti F, Ippoliti R, Parente A
Mol Biosyst (ISSN: 1742-206x)
,
2010;
6(3): 570-579.
Impact Factor:
3.825
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Crystal structure of PD-L1, a ribosome inactivating protein from Phytolacca dioica L. leaves with the property to induce DNA cleavage
(
567 views
)
Ruggiero A
, Di Maro A, Severino V, Chambery A,
Berisio R
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print)
,
2009 Dec;
91(12): 1135-1142.
Impact Factor:
2.605
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The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability
(
580 views
)
Ruggiero A
, Masullo M,
Marasco D
, Ruocco MR, Grimaldi P, Arcari P, Zagari A,
Vitagliano L
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic)
,
2009 Dec;
77(4): 1004-1008.
Impact Factor:
3.085
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Biochemical Characterisation Of The D60a Mutant Of The Elongation Factor 1 Alpha From The Archaeon Sulfolobus Solfataricus
(
473 views
)
Ruggiero I, Cantiello P, Lamberti A, Sorrentino A, Martucci NM,
Ruggiero A
, Arcone R,
Vitagliano L
, Arcari P, Masullo M
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic)
,
2009 Jul;
91(7): 835-842.
Impact Factor:
3.897
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Crystallization and preliminary X-ray crystallographic analysis of two dimeric hyperthermostable thioredoxins isolated from Sulfolobus solfataricus
(
480 views
)
Ruggiero A
, Lanzotti MA, Ruocco MR, Grimaldi P,
Marasco D
, Arcari P, Masullo M, Zagari A,
Vitagliano L
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309)
,
2009 Jun;
65: 604-607.
Impact Factor:
0.551
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Molecular dynamics studies of the P pilus rod subunit PapA
(
807 views
)
Vitagliano L
,
Ruggiero A
,
Pedone C
,
Berisio R
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print)
,
2009 Mar;
15(3): 192-199.
Impact Factor:
1.807
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Role of side chains in collagen triple helix stabilization and partner recognition
(
956 views
)
Berisio R
, De Simone A,
Ruggiero A
,
Improta R
,
Vitagliano L
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print)
,
2009 Mar;
15(3): 131-140.
Impact Factor:
1.807
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Structure and stability of a thioredoxin reductase from Sulfolobus solfataricus: A thermostable protein with two functions
(
660 views
)
Ruggiero A
, Masullo M, Ruocco MR, Grimaldi P, Lanzotti MA, Arcari P, Zagari A,
Vitagliano L
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439)
,
2009 Mar;
1794(3): 554-562.
Impact Factor:
2.48
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Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis
(
832 views
)
Ruggiero A
, Tizzano B,
Pedone E
,
Pedone C
, Wilmanns M,
Berisio R
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic)
,
2009 Jan 9;
385(1): 153-162.
Impact Factor:
3.871
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Conformational states and association mechanism of Yersinia pestis Caf1 subunits
(
581 views
)
Vitagliano L
,
Ruggiero A
,
Pedone C
,
Berisio R
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic)
,
2008 Sep 8;
372(4): 804-810.
Impact Factor:
2.648
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Characterisation of the components of the thioredoxin system in the archaeon Sulfolobus solfataricus
(
538 views
)
Grimaldi P, Ruocco MR, Lanzotti MA,
Ruggiero A
, Ruggiero I, Arcari P,
Vitagliano L
, Masullo M
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic)
,
2008 Jul;
12(4): 553-562.
Impact Factor:
1.782
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Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis
(
581 views
)
Esposito C, Pethoukov MV, Svergun DI,
Ruggiero A
,
Pedone C
,
Pedone E
,
Berisio R
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530)
,
2008 Jul;
190(13): 4749-4753.
Impact Factor:
3.636
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Atomic Resolution (1. 1 Angstrom) Structure Of The Ribosome-Inactivating Protein Pd-L4 From Phytolacca Dioica L. Leaves
(
793 views
)
Ruggiero A
, Chambery A, Di Maro A, Parente A,
Berisio R
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic)
,
2008 Apr;
71(1): 8-15.
Impact Factor:
3.419
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Stability Against Temperature Of Sulfolobus Solfataricus Elongation Factor 1 Alpha, A Multi-Domain Protein
(
707 views
)
Granata V, Graziano G,
Ruggiero A
, Raimo G, Masullo M, Arcari P,
Vitagliano L
, Zagari A
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439)
,
2008 Apr;
1784(4): 573-581.
Impact Factor:
2.233
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Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis
(
584 views
)
Ruggiero A
, Tizzano B, Geerlof A,
Pedone E
,
Pedone C
, Wilmanns M,
Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309)
,
2007 Oct 1;
63(10): 870-873.
Impact Factor:
0.645
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A Molecular Dynamics Study of Pilus Subunits: Insights into Pilus Biogenesis
(
620 views
)
Vitagliano L
,
Ruggiero A
,
Pedone C
,
Berisio R
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic)
,
2007 Apr 6;
367(4): 935-941.
Impact Factor:
4.472
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Crystallization and preliminary X-ray diffraction analysis of PD-L1, a highly glycosylated ribosome inactivating protein with DNase activity
(
776 views
)
Ruggiero A
, Chambery A, Di Maro A, Mastroianni A, Parente A,
Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305)
,
2007;
14(4): 407-409.
Impact Factor:
1.097
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Crystallization and preliminary x-ray diffraction analysis of PD-L4, a ribosome inactivating protein from Phytolacca dioica L. leaves
(
456 views
)
Ruggiero A
, Chambery A, Di Maro A, Pisante M, Parente A,
Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305)
,
2007;
14(1): 97-100.
Impact Factor:
1.097
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Chemical Denaturation Of The Elongation Factor 1 Alpha Isolated From The Hyperthermophilic Archaeon Sulfolobus Solfataricus
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608 views
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Granata V, Graziano G,
Ruggiero A
, Raimo G, Masullo M, Arcari P,
Vitagliano L
, Zagari A
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic)
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2006 Jan 24;
45(3): 719-726.
Impact Factor:
3.633
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Crystallization And Preliminary X-Ray Crystallographic Analysis Of The Sulfolobus Solfataricus Nucleotide-Exchange Factor 1 Beta
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501 views
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Ruggiero A
, Masullo M, Arcari P, Raimo G,
Vitagliano L
, Zagari A
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309)
,
2005 Nov;
61(11): 1000-1002.
Impact Factor:
0.568
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Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase
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Ruggiero A
, Ruocco MR, Grimaldi P, Arcari P, Masullo M, Zagari A,
Vitagliano L
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309)
,
2005 Oct;
61: 906-909.
Impact Factor:
0.568
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The Crystal Structure Of Sulfolobus Solfataricus Elongation Factor 1 Alpha In Complex With Magnesium And Gdp
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632 views
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Vitagliano L
,
Ruggiero A
, Masullo M, Cantiello P, Arcari P, Zagari A
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic)
,
2004;
43(21): 6630-6636.
Impact Factor:
4.008
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93
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92
excluding Abstracts).
Total impact factor:
390.947
(
387.217
excluding Abstracts).
Total 5 year impact factor:
373.175
(
368.931
excluding Abstracts).
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