* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (492 views)
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
Impact Factor: 1.849
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* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (644 views)
Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2010 Sep 8; 18(9): 1184-1190.
Impact Factor: 6.337
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* Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus (684 views)
Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
Impact Factor: 1.849
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (506 views)
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
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* X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus (1019 views)
Ruggiero A, Squeglia F, Marasco D, Marchetti R, Molinaro A, Berisio R
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2011 Apr 1; 435(1): 33-41.
Impact Factor: 4.897
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* Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy (451 views)
Squeglia F, Marchetti R, Ruggiero A, Lanzetta R, Marasco D, Dworkin J, Petoukhov M, Molinaro A, Berisio R, Silipo A
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2011 Dec 28; 133(51): 20676-20679.
Impact Factor: 9.907
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* Enhanced crystallizability by protein engineering approaches: A general overview (2160 views)
Ruggiero A, Smaldone G, Squeglia F, Berisio R
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Jul; 19(7): 732-742.
Impact Factor: 1.994
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* Structural and Dynamic properties of incomplete immunoglobulin-like fold domains (682 views)
Berisio R, Ciccarelli L, Squeglia F, De Simone A, Vitagliano L
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1045-1053.
Impact Factor: 1.994
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* Bacterial cell division regulation by Ser/Thr kinases: A structural perspective (694 views)
Ruggiero A, De Simone P, Smaldone G, Squeglia F, Berisio R
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 756-766.
Impact Factor: 2.326
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* Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis (689 views)
Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2013 Feb 1; 31(2): 195-205.
Impact Factor: 2.983
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* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (696 views)
Squeglia F, Romano M, Ruggiero A, Vitagliano L, De Simone A, Berisio R
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
Impact Factor: 3.832
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* Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2. 3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes (502 views)
Squeglia F, Bachert B, Romano M, Lukomski S, Berisio R
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Sep; 69(9): 1023-1025.
Impact Factor: 0.568
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* Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization (1650 views)
Hayafune M, Berisio R, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S, Squeglia F, Ruggiero A, Tokuyasu K, Molinaro A, Kaku H, Shibuya N
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Jan 21; 111(3): E404-E404.
Impact Factor: 9.674
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* The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 (667 views)
Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2014 Feb 21; 289(8): 5122-5133.
Impact Factor: 4.573
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* Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (781 views)
Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
Impact Factor: 2.385
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* Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine (577 views)
Squeglia F, Ruggiero A, Romano M, Vitagliano L, Berisio R
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Sep; 70(9): 2295-2300.
Impact Factor: 14.1
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* Differential thermodynamic behaviours of the extra-cellular regions of two Ser/Thr PrkC kinases revealed by calorimetric studies (542 views)
Berisio R, Squeglia F, Ruggiero A, Petraccone L, Stellato MI, Del Vecchio P
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Feb 8; 1854(5): 402-409.
Impact Factor: 5.158
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* Exit from mycobacterial dormancy: a structural perspective (705 views)
Squeglia F, Ruggiero A, Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Feb 9; 22(14): 1698-1709.
Impact Factor: 3.455
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* Structure and Function of RNase AS, a Novel Virulence Factor from Mycobacterium Tuberculosis (592 views)
Romano M, Squeglia F, Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Apr 17; 22(14): 1745-1756.
Impact Factor: 3.455
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* The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains (468 views)
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2015 Nov 5; 1860(2): 445-451.
Impact Factor: 4.864
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* Use of hydrolytic enzymes for algal biomass treatment (390 views)
Ruggiero A, Squeglia F, Romano M, Berisio R
Current Biotechnology, 2016; 5: 296-304.
Impact Factor: 2.922
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* Unique Footprint in the scl1. 3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus (418 views)
Bachert BA, Choi SJ, Lasala PR, Harper TI, Mcnitt DH, Boehm DT, Caswell CC, Ciborowski P, Keene DR, Flores AR, Musser JM, Squeglia F, Marasco D, Berisio R, Lukomski S
Front Cell Infect Mi (ISSN: 2235-2988), 2016 Aug 31; 6: 90-90.
Impact Factor: 4.3
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* Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy (520 views)
Majkowska-skrobek G, Latka A, Berisio R, Maciejewska B, Squeglia F, RomanoM, Lavigne R, Struve C, Drulis-kawa Z
Viruses (ISSN: 1999-4915, 1999-4915linking, 1999-4915electronic), 2016 Dec 1; 8(12): N/D-N/D.
Impact Factor: 3.465
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* Collagen-like proteins of pathogenic streptococci (310 views)
Lukomski S, Bachert B, Squeglia F, Berisio R
Mol Microbiol (ISSN: 0950-382x), 2017; 103: 919-930.
Impact Factor: 3.816
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* Molecular mechanisms of defense response induced by chitin oligosaccharides (394 views)
Berisio R, Ruggiero A, Squeglia F, Esposito C, Molinaro A, Silipo A, Marchetti R, Shibuya N
Research Reports, 2017; N/D: N/D-N/D.
Impact Factor: 0
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* Structural and dynamic features of PASTA domains with different functional roles (403 views)
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
Journal Of Biomolecular Structure & Dynamics, 2017; 35(10): 2293-2300.
Impact Factor: 3.123
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* Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis (499 views)
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2017 May; 35(6): 1322-1330.
Impact Factor: 3.107
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* Defense Against Pathogens: Structural Insights into the Mechanism of Chitin Induced Activation of Innate Immunity (340 views)
Squeglia F, Berisio R, Shibuya N, Kaku H
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3980-3986.
Impact Factor: 3.469
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* Editorial: Molecular Scenarios Behind Infectious Diseases (513 views)
Berisio R, Squeglia F, Ruggiero A
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3939-3941.
Impact Factor: 3.469
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* Molecular players in Tuberculosis drug development: another break in the cell wall (429 views)
Squeglia F, Romano M, Ruggiero A, Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3954-3969.
Impact Factor: 3.469
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* PASTA in Penicillin Binding Proteins and Serine/Threonine Kinases: A Recipe of Structural, Dynamic and Binding Properties (391 views)
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 4038-4056.
Impact Factor: 3.469
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* Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation (570 views) (PDF 247 views)
Squeglia F, Ruggiero A, Berisio R
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018; 24: 2533-2546.
Impact Factor: 5.317
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* Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin (347 views)
Mcnitt DH, Choi SJ, Keene DR, Van De Water L, Squeglia F, Berisio R, Lukomski S
J Biol Chem, 2018; N/D: N/D-N/D.
Impact Factor: 4.12
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* The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis (416 views)
Squeglia F, Berisio R, Ruggiero A
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xelectronic, 2053-230xlinking), 2018 Jan 1; 74(Pt1): 1-5.
Impact Factor: 0.8
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* A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics (319 views)
Squeglia F, Ruggiero A, De Simone A, Berisio R
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Feb; 27(2): 369-380.
Impact Factor: 2.523
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* Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation (204 views)
Squeglia F, Ruggiero A, Berisio R
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2018 Feb 21; 24 (11 ): 2533-2546.
Impact Factor: 5.476
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* PASTA sequence composition is a predictive tool for protein class identification (364 views)
Calvanese L, Falcigno L, Squeglia F, Berisio R, D'Auria G
Amino Acids (ISSN: 1438-2199electronic, 0939-4451linking), 2018 Oct; 50(10): 1441-1450.
Impact Factor: 4.106
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* Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest (491 views)
Squeglia F, Ruggiero A, Berisio R
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2018 Oct 11; 475(19): 3123-3140.
Impact Factor: 4.897
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* Phage-Borne Depolymerases Decrease Klebsiella pneumoniae Resistance to Innate Defense Mechanisms (649 views)
Majkowska-skrobek G, Latka A, Berisio R, Squeglia F, Maciejewska B, Briers Y, Drulis-kawa Z
Front Microbiol (ISSN: 1664-302xprint, 1664-302xlinking, 1664-302xelectronic), 2018 Oct 23; 9(OCT): 2517-2517.
Impact Factor: 4.076
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* The Mycobacterial HBHA Protein: a Promising Biomarker for Tuberculosis (343 views)
De Maio F, Squeglia F, Goletti D, Delogu G
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018 Oct 29; 26(11): 2051-2060.
Impact Factor: 3.519
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* The Cell Wall Hydrolytic NlpC/P60 Endopeptidases in Mycobacterial Cytokinesis: A Structural Perspective (362 views)
Squeglia F, Moreira M, Ruggiero A, Berisio R
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2019 Jun 18; 8(6): N/D-N/D.
Impact Factor: 5.7
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The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima (212 views)
Smaldone G, Ruggiero A, Balasco N, Abuhammad A, Autiero I, Caruso D, Esposito D, Ferraro G, Gelardi E, L , M , Moreira M, Quareshy M, Romano M, Saaret A, Selvam I, Squeglia F, Troisi R, Kroon-batenburg L, M , J , Esposito L, Berisio R, Vitagliano L
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xlinking), 2019 Nov 1; 75(Pt11): 707-713.
Impact Factor: 0.968
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* Structural and dynamic studies provide insights into specificity and allosteric regulation of Ribonuclease AS, a key enzyme in mycobacterial virulence (336 views) (PDF 25 views)
Calvanese L, Squeglia F, Romano M, D'Auria G, Falcigno L, Berisio R
J Biomol Struct Dyn (ISSN: 0739-1102linking, 1538-0254electronic), 2020; N/D: 1-19.
Impact Factor: 3.11
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* A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping (785 views)
Romano M, Ruggiero A, Squeglia F, Maga G, Berisio R
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2020 May 20; 9(5): 1297-1297.
Impact Factor: 6.6
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* Structural and Functional Studies of a Klebsiella Phage Capsule Depolymerase Tailspike: Mechanistic Insights into Capsular Degradation (209 views)
Squeglia F, Maciejewska B, Łątka A, Ruggiero A, Briers Y, Drulis-kawa Z, Berisio R
Structure (ISSN: 0969-2126linking, 1878-4186), 2020 Jun 2; 28(6): 613-624.
Impact Factor: 4.86
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* Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins (169 views)
Squeglia F, Romano M, Ruggiero A, Maga G, Berisio R
Front Chem (ISSN: 2296-2646linking), 2020 Dec 10; 8: 602162-602162.
Impact Factor: 3.693
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* PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response (105 views)
Kramarska E, Squeglia F, De Maio F, Delogu G, Berisio R
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2021 Jan 15; 10(1): N/D-N/D.
Impact Factor: 6.6
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* Structural and Binding Properties of the Active Cell Wall Hydrolase RipA from M. tuberculosis, a Promising Biosensing Molecule for Early Warning Bacterial Detection (86 views)
Squeglia F, Marasco D, Ruggiero A, Testa G, Esposito L, Berisio R
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2022; 29(24): 4282-4292.
Impact Factor: 4.74
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* Structural and Biochemical Characterization of Endo--1, 4-glucanase from Dictyoglomus thermophilum, a Hyperthermostable and Halotolerant Cellulase (119 views) (PDF 23 views)
Berisio R, Barra G, Romano M, Squeglia F, Ruggiero A
Catalysts, 2022; 302: N/D-N/D.
Impact Factor: 4.5
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* Structure-Based Development of SARS-CoV-2 Spike Interactors (77 views)
Squeglia F, Romano M, Esposito L, Barra G, Campiglia P, Sala M, Scala MC, Ruggiero A, Berisio R
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic), 2022 May 17; 23(10): N/D-N/D.
Impact Factor: 6.21
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* Structure based design of effective HtpG-derived vaccine antigens against M. tuberculosis (92 views)
Ruggiero A, Choi HG, Barra G, Squeglia F, Back YW, Kim HJ, Berisio R
Front Mol Biosci (ISSN: 2296-889xlinking), 2022 Aug 11; 9: 964645-964645.
Impact Factor: 6.11
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* A Structural View at Vaccine Development against M. tuberculosis (112 views)
Romano M, Squeglia F, Kramarska E, Barra G, Choi HG, Kim HJ, Ruggiero A, Berisio R
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2023 Jan 14; 12(2): N/D-N/D.
Impact Factor: 7.7
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* Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation (134 views)
Sandomenico A, Ruggiero A, Iaccarino E, Oliver A, Squeglia F, Moreira M, Esposito L, Ruvo M, Berisio R
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic), 2023 May 10; 24(10): 500-519.
Impact Factor: 6.21
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